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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1994 7
1995 8
1996 4
1997 5
1998 10
1999 6
2000 10
2001 11
2002 17
2003 7
2004 14
2005 21
2006 19
2007 18
2008 23
2009 21
2010 19
2011 22
2012 35
2013 30
2014 37
2015 36
2016 31
2017 22
2018 32
2019 20
2020 32
2021 26
2022 7
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490 results
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Page 1
Galectin-3 and cancer stemness.
Nangia-Makker P, Hogan V, Raz A. Nangia-Makker P, et al. Glycobiology. 2018 Apr 1;28(4):172-181. doi: 10.1093/glycob/cwy001. Glycobiology. 2018. PMID: 29315388 Free PMC article. Review.
This structural complexity permits galectin-3 to associate with numerous molecules utilizing protein-protein and/or protein-carbohydrate interactions in the extra-cellular as well as intracellular milieu and regulate diverse signaling pathways, a number of which app …
This structural complexity permits galectin-3 to associate with numerous molecules utilizing protein-protein and/or protein-ca …
Platelet glycoprotein VI promotes metastasis through interaction with cancer cell-derived galectin-3.
Mammadova-Bach E, Gil-Pulido J, Sarukhanyan E, Burkard P, Shityakov S, Schonhart C, Stegner D, Remer K, Nurden P, Nurden AT, Dandekar T, Nehez L, Dank M, Braun A, Mezzano D, Abrams SI, Nieswandt B. Mammadova-Bach E, et al. Blood. 2020 Apr 2;135(14):1146-1160. doi: 10.1182/blood.2019002649. Blood. 2020. PMID: 32040544 Free article.
Increasing evidence suggests that platelets play a predominant role in colon and breast cancer metastasis, but the underlying molecular mechanisms remain elusive. ...In vitro and in vivo analyses supported that mouse, as well as human GPVI, had platelet adhesion to …
Increasing evidence suggests that platelets play a predominant role in colon and breast cancer metastasis, but the underlying …
Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis.
Caputo S, Grioni M, Brambillasca CS, Monno A, Brevi A, Freschi M, Piras IS, Elia AR, Pieri V, Baccega T, Lombardo A, Galli R, Briganti A, Doglioni C, Jachetti E, Bellone M. Caputo S, et al. Front Immunol. 2020 Sep 10;11:1820. doi: 10.3389/fimmu.2020.01820. eCollection 2020. Front Immunol. 2020. PMID: 33013832 Free PMC article.
Galectin-3 (Gal-3) is an extracellular matrix glycan-binding protein with several immunosuppressive and pro-tumor functions. The role of Galectin-3 in cancer stem-like cells (CSCs) is poorly investigated. ...
Galectin-3 (Gal-3) is an extracellular matrix glycan-binding protein with several immunosuppressive and pro-tumor funct …
Galectin-3 Inhibits Cancer Metastasis by Negatively Regulating Integrin β3 Expression.
Hayashi Y, Jia W, Kidoya H, Muramatsu F, Tsukada Y, Takakura N. Hayashi Y, et al. Am J Pathol. 2019 Apr;189(4):900-910. doi: 10.1016/j.ajpath.2018.12.005. Epub 2019 Jan 14. Am J Pathol. 2019. PMID: 30653955 Free article.
Galectin-3 (Gal-3; gene LGALS3) is a member of the beta-galactose-binding lectin family. ...It was found that overexpression of Gal-3 in melanoma cells in fact suppresses metastasis. In contrast, knocking out Gal-3 expression in cancer …
Galectin-3 (Gal-3; gene LGALS3) is a member of the beta-galactose-binding lectin family. ...It was found that overexpre …
Galectin-3 in cancer.
Song L, Tang JW, Owusu L, Sun MZ, Wu J, Zhang J. Song L, et al. Clin Chim Acta. 2014 Apr 20;431:185-91. doi: 10.1016/j.cca.2014.01.019. Epub 2014 Feb 12. Clin Chim Acta. 2014. PMID: 24530298 Review.
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated evidences indicate that Gal-3 is closely involved in tumor cell transformation, migratio …
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis i …
An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.
Vuong L, Kouverianou E, Rooney CM, McHugh BJ, Howie SEM, Gregory CD, Forbes SJ, Henderson NC, Zetterberg FR, Nilsson UJ, Leffler H, Ford P, Pedersen A, Gravelle L, Tantawi S, Schambye H, Sethi T, MacKinnon AC. Vuong L, et al. Cancer Res. 2019 Apr 1;79(7):1480-1492. doi: 10.1158/0008-5472.CAN-18-2244. Epub 2019 Jan 23. Cancer Res. 2019. PMID: 30674531
To examine the role of galectin-3 inhibition in NSCLC, we tested the effects of galectin-3 depletion using genetic and pharmacologic approaches on syngeneic mouse lung adenocarcinoma and human lung adenocarcinoma xenografts. ...Oral administration of a …
To examine the role of galectin-3 inhibition in NSCLC, we tested the effects of galectin-3 depletion using genet …
Chitinase-3 like-protein-1 function and its role in diseases.
Zhao T, Su Z, Li Y, Zhang X, You Q. Zhao T, et al. Signal Transduct Target Ther. 2020 Sep 14;5(1):201. doi: 10.1038/s41392-020-00303-7. Signal Transduct Target Ther. 2020. PMID: 32929074 Free PMC article. Review.
Moreover, following its initial identification in the culture supernatant of the MG63 osteosarcoma cell line, CHI3L1 has been shown to be overexpressed in a wealth of both human cancers and animal tumor models. To date, interleukin-13 receptor subunit alpha-2, transmembran …
Moreover, following its initial identification in the culture supernatant of the MG63 osteosarcoma cell line, CHI3L1 has been shown to be ov …
Role of the interaction between galectin-3 and cell adhesion molecules in cancer metastasis.
Xin M, Dong XW, Guo XL. Xin M, et al. Biomed Pharmacother. 2015 Feb;69:179-85. doi: 10.1016/j.biopha.2014.11.024. Epub 2014 Nov 24. Biomed Pharmacother. 2015. PMID: 25661355 Review.
Galectin-3, a unique chimera-type member of the beta-galactoside-binding soluble lectin family, is present in both normal and cancer cells and plays a crucial role in the regulation of cell adhesion. ...Cell adhesion molecules (CAMs) are membrane receptors th …
Galectin-3, a unique chimera-type member of the beta-galactoside-binding soluble lectin family, is present in both normal and …
Galectin-3--a jack-of-all-trades in cancer.
Newlaczyl AU, Yu LG. Newlaczyl AU, et al. Cancer Lett. 2011 Dec 27;313(2):123-8. doi: 10.1016/j.canlet.2011.09.003. Epub 2011 Sep 17. Cancer Lett. 2011. PMID: 21974805 Review.
Changes in galectin-3 expression and subcellular and intercellular localizations are commonly seen in cancer and pre-cancerous conditions. ...This mini-review summaries the diverse influences of galectin-3 on cancer cell behaviours …
Changes in galectin-3 expression and subcellular and intercellular localizations are commonly seen in cancer and pre- …
The expression of Galectin-3 in endometrial cancer: a systematic review of the literature.
Boutas I, Kontogeorgi A, Dimitrakakis C, Kalantaridou SN. Boutas I, et al. Mol Biol Rep. 2021 Jul;48(7):5699-5705. doi: 10.1007/s11033-021-06536-1. Epub 2021 Jul 9. Mol Biol Rep. 2021. PMID: 34241773
Galectin-3 has been utilized through the years as a diagnostic and prognostic marker for various types of cancers. ...CONCLUSIONS: The part Galectin-3 might potentially have in metastasis of cancers and the offering of a better pro …
Galectin-3 has been utilized through the years as a diagnostic and prognostic marker for various types of cancers. ...C …
490 results