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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1994 7
1995 8
1996 4
1997 5
1998 10
1999 6
2000 10
2001 11
2002 17
2003 7
2004 14
2005 21
2006 19
2007 18
2008 23
2009 21
2010 19
2011 22
2012 35
2013 30
2014 37
2015 36
2016 31
2017 22
2018 32
2019 19
2020 27
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459 results
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Page 1
Galectin-3 and cancer stemness.
Nangia-Makker P, Hogan V, Raz A. Nangia-Makker P, et al. Glycobiology. 2018 Apr 1;28(4):172-181. doi: 10.1093/glycob/cwy001. Glycobiology. 2018. PMID: 29315388 Free PMC article. Review.
Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been unique due to the regulatory roles it performs in processes associated with tumor progression and metastasis such as cell proliferat …
Over the last few decades galectin-3, a carbohydrate binding protein, with affinity for N-acetyllactosamine residues, has been …
Galectin-3 Inhibits Cancer Metastasis by Negatively Regulating Integrin β3 Expression.
Hayashi Y, Jia W, Kidoya H, Muramatsu F, Tsukada Y, Takakura N. Hayashi Y, et al. Am J Pathol. 2019 Apr;189(4):900-910. doi: 10.1016/j.ajpath.2018.12.005. Epub 2019 Jan 14. Am J Pathol. 2019. PMID: 30653955 Free article.
It was found that overexpression of Gal-3 in melanoma cells in fact suppresses metastasis. In contrast, knocking out Gal-3 expression in cancer cells promoted cell aggregation mediated through interactions with platelets and fibrinogen in vitro and inc …
It was found that overexpression of Gal-3 in melanoma cells in fact suppresses metastasis. In contrast, knocking out Gal-3 …
The clinical importance of serum galectin-3 levels in breast cancer patients with and without metastasis.
Topcu TO, Kavgaci H, Gunaldi M, Kocoglu H, Akyol M, Mentese A, Yaman SO, Orem A, Ozdemir F, Aydin F. Topcu TO, et al. J Cancer Res Ther. 2018 Sep;14(Supplement):S583-S586. doi: 10.4103/0973-1482.176425. J Cancer Res Ther. 2018. PMID: 30249872 Free article.
OBJECTIVE: Studies have investigated expression status of galectin-3 (Gal-3), but very little is known about the importance of circulating Gal-3 in patients with breast cancer (BC). ...Levels of Gal-3 were investigated in BC patients and …
OBJECTIVE: Studies have investigated expression status of galectin-3 (Gal-3), but very little is known about the import …
Galectin 3 as a guardian of the tumor microenvironment.
Ruvolo PP. Ruvolo PP. Biochim Biophys Acta. 2016 Mar;1863(3):427-437. doi: 10.1016/j.bbamcr.2015.08.008. Epub 2015 Aug 8. Biochim Biophys Acta. 2016. PMID: 26264495 Free article. Review.
Galectin 3's ability to support cancer cell survival by intra-cellular and extra-cellular mechanisms suggests this molecule is an important component of the tumor microenvironment that potentially could be targeted for therapy. Data is emerging that …
Galectin 3's ability to support cancer cell survival by intra-cellular and extra-cellular mechanisms suggests th …
Galectin-3 in cancer.
Song L, Tang JW, Owusu L, Sun MZ, Wu J, Zhang J. Song L, et al. Clin Chim Acta. 2014 Apr 20;431:185-91. doi: 10.1016/j.cca.2014.01.019. Epub 2014 Feb 12. Clin Chim Acta. 2014. PMID: 24530298 Review.
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis in normal and pathologic tissues. Accumulated evidences indicate that Gal-3 is closely involved in tumor cell transformation, migratio …
Galectin-3 (Gal-3) plays important roles in cell proliferation, adhesion, differentiation, angiogenesis and apoptosis i …
Synergistic interaction between galectin-3 and carcinoembryonic antigen promotes colorectal cancer metastasis.
Wu KL, Huang EY, Yeh WL, Hsiao CC, Kuo CM. Wu KL, et al. Oncotarget. 2017 Jun 27;8(37):61935-61943. doi: 10.18632/oncotarget.18721. eCollection 2017 Sep 22. Oncotarget. 2017. PMID: 28977916 Free PMC article.
In this study, we investigated the role of galectin-3 and carcinoembryonic antigen (CEA) in metastasis and survival of colorectal cancer (CRC) patients. ...These findings suggest interaction between galectin-3 and CEA promotes CRC migrati …
In this study, we investigated the role of galectin-3 and carcinoembryonic antigen (CEA) in metastasis and survival of …
Roles of galectin-3 in metabolic disorders and tumor cell metabolism.
Li YS, Li XT, Yu LG, Wang L, Shi ZY, Guo XL. Li YS, et al. Int J Biol Macromol. 2020 Jan 1;142:463-473. doi: 10.1016/j.ijbiomac.2019.09.118. Epub 2019 Oct 8. Int J Biol Macromol. 2020. PMID: 31604080 Review.
The galactoside-binding protein galectin-3 is commonly overexpressed by cancer cells and promotes cancer progression and metastasis. ...This brief review summarizes the current understanding of the roles and actions of galectin-3 i …
The galactoside-binding protein galectin-3 is commonly overexpressed by cancer cells and promotes cancer progres …
An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.
Vuong L, Kouverianou E, Rooney CM, McHugh BJ, Howie SEM, Gregory CD, Forbes SJ, Henderson NC, Zetterberg FR, Nilsson UJ, Leffler H, Ford P, Pedersen A, Gravelle L, Tantawi S, Schambye H, Sethi T, MacKinnon AC. Vuong L, et al. Cancer Res. 2019 Apr 1;79(7):1480-1492. doi: 10.1158/0008-5472.CAN-18-2244. Epub 2019 Jan 23. Cancer Res. 2019. PMID: 30674531 Free article.
Galectin-3 is a β-galactoside-binding lectin that is highly expressed within the tumor microenvironment of aggressive cancers and whose expression correlates with poor survival particularly in patients with non-small cell lung cancer (NSCLC). ...Oral a …
Galectin-3 is a β-galactoside-binding lectin that is highly expressed within the tumor microenvironment of aggressive cance …
The expression of galectin-3 in breast cancer and its association with chemoresistance: a systematic review of the literature.
Boutas I, Potiris A, Brenner W, Lebrecht A, Hasenburg A, Kalantaridou S, Schmidt M. Boutas I, et al. Arch Gynecol Obstet. 2019 Nov;300(5):1113-1120. doi: 10.1007/s00404-019-05292-9. Epub 2019 Sep 9. Arch Gynecol Obstet. 2019. PMID: 31502061
It seems that galectin-3 plays an important role in tumor progression, cell growth, invasion and metastasis. Galectin-3 is the only member of the chimeric galectins that has an N-terminal glycine and proline domain and a C-terminal carbohydrate …
It seems that galectin-3 plays an important role in tumor progression, cell growth, invasion and metastasis. Galecti …
Galectin-3 and metastasis.
Takenaka Y, Fukumori T, Raz A. Takenaka Y, et al. Glycoconj J. 2002;19(7-9):543-9. doi: 10.1023/B:GLYC.0000014084.01324.15. Glycoconj J. 2002. PMID: 14758078 Review.
Galectin-3 is expressed widely in epithelial and immune cells and its expression is correlated with cancer aggressiveness and metastasis. ...Recently, we and others have shown that galectin-3 can be a reliable diagnostic marker in certain …
Galectin-3 is expressed widely in epithelial and immune cells and its expression is correlated with cancer aggressivene …
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