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1995 1
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2004 3
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2006 1
2007 2
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2009 6
2010 8
2011 6
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2013 11
2014 5
2015 7
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2020 5
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84 results
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Page 1
Galectin-3 and cancer stemness.
Nangia-Makker P, Hogan V, Raz A. Nangia-Makker P, et al. Glycobiology. 2018 Apr 1;28(4):172-181. doi: 10.1093/glycob/cwy001. Glycobiology. 2018. PMID: 29315388 Free PMC article. Review.
This structural complexity permits galectin-3 to associate with numerous molecules utilizing protein-protein and/or protein-carbohydrate interactions in the extra-cellular as well as intracellular milieu and regulate diverse signaling pathways, a number of which app …
This structural complexity permits galectin-3 to associate with numerous molecules utilizing protein-protein and/or protein-ca …
Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis.
Caputo S, Grioni M, Brambillasca CS, Monno A, Brevi A, Freschi M, Piras IS, Elia AR, Pieri V, Baccega T, Lombardo A, Galli R, Briganti A, Doglioni C, Jachetti E, Bellone M. Caputo S, et al. Front Immunol. 2020 Sep 10;11:1820. doi: 10.3389/fimmu.2020.01820. eCollection 2020. Front Immunol. 2020. PMID: 33013832 Free PMC article.
The role of Galectin-3 in cancer stem-like cells (CSCs) is poorly investigated. ...In fact, the prevalent nuclear and cytoplasmic distribution of Gal-3 in prostate CSCs made them less susceptible to apoptosis, when compared to more differentiate …
The role of Galectin-3 in cancer stem-like cells (CSCs) is poorly investigated. ...In fact, the prevalent nuclear and c …
Overexpression of the galectin-3 during tumor progression in prostate cancer and its clinical implications.
Gao J, Li T, Mo Z, Hu Y, Yi Q, He R, Zhu X, Zhou X, She S, Chen Y. Gao J, et al. Int J Clin Exp Pathol. 2018 Feb 1;11(2):839-846. eCollection 2018. Int J Clin Exp Pathol. 2018. PMID: 31938173 Free PMC article.
Galectin-3 (gal-3) is a carbohydrate-binding protein involved in cancer progression and metastasis, including prostate tissues. ...Our results showed gal-3 cleavage occurred in prostate cancer but not normal prostate.
Galectin-3 (gal-3) is a carbohydrate-binding protein involved in cancer progression and metastasis, including
Galectin-3 and cancer (Review).
Califice S, Castronovo V, Van Den Brûle F. Califice S, et al. Int J Oncol. 2004 Oct;25(4):983-92. Int J Oncol. 2004. PMID: 15375548 Review.
Its carbohydrate-binding properties constitute the basis for cell-cell and cell-matrix interactions and cancer progression. Modulation of galectin-3 expression in cancer cells has indeed been reported. These observations lead to the recognition of g
Its carbohydrate-binding properties constitute the basis for cell-cell and cell-matrix interactions and cancer progression. Modulatio …
Combining inhibition of galectin-3 with and before a therapeutic vaccination is critical for the prostate-tumor-free outcome.
Tiraboschi C, Gentilini L, Velazquez C, Corapi E, Jaworski FM, Garcia Garcia JD, Rondón Y, Chauchereau A, Laderach DJ, Compagno D. Tiraboschi C, et al. J Immunother Cancer. 2020 Dec;8(2):e001535. doi: 10.1136/jitc-2020-001535. J Immunother Cancer. 2020. PMID: 33293356 Free PMC article.
We also used two different methods to inhibit the expression of galectin-3 (Gal-3) in tumor cells: a stable RNA interference method to control the expression of this galectin efficiently only in tumor cells, and low and non-cytotoxic doses of docetaxel …
We also used two different methods to inhibit the expression of galectin-3 (Gal-3) in tumor cells: a stable RNA interfe …
Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis.
Nakajima K, Kho DH, Yanagawa T, Harazono Y, Hogan V, Chen W, Ali-Fehmi R, Mehra R, Raz A. Nakajima K, et al. Cancer Res. 2016 Mar 15;76(6):1391-402. doi: 10.1158/0008-5472.CAN-15-1793. Epub 2016 Feb 2. Cancer Res. 2016. PMID: 26837763 Free PMC article.
Proteolytic cleavage of Gal-3 may also contribute to malignant cellular behaviors, but has not been addressed in cancer metastasis. ...Pathologically, bone metastatic cancers expressed and released an intact form of Gal-3, mainly detected in breast cancer
Proteolytic cleavage of Gal-3 may also contribute to malignant cellular behaviors, but has not been addressed in cancer metast …
Positive associations between galectin-3 and PSA levels in prostate cancer patients: a prospective clinical study-I.
Nakajima K, Heilbrun LK, Hogan V, Smith D, Heath E, Raz A. Nakajima K, et al. Oncotarget. 2016 Dec 13;7(50):82266-82272. doi: 10.18632/oncotarget.12619. Oncotarget. 2016. PMID: 27741512 Free PMC article.
Galectin-3 (Gal-3), an oncogenic pro-inflammatory protein, has been suggested as a possible complementary diagnostic candidate to prostate specific antigen (PSA) blood test for prostate cancer patients. ...The data show positive associati
Galectin-3 (Gal-3), an oncogenic pro-inflammatory protein, has been suggested as a possible complementary diagnostic ca
Development of (G3-C12)-mediated camptothecin polymeric prodrug targeting to Galectin-3 receptor against androgen-independent prostate cancer.
Yuan X, Liu L, Wang W, Gao YR, Zhang D, Jia TT, Zeng HR, Pan G, Yuan Y. Yuan X, et al. Int J Pharm. 2020 Apr 30;580:119123. doi: 10.1016/j.ijpharm.2020.119123. Epub 2020 Feb 5. Int J Pharm. 2020. PMID: 32035258
In this study, we synthesized a novel G3-C12-mediated esterase-sensitive tumor-targeting polymeric prodrug of camptothecin (CPT), P(OEGMA-co-CPT-co-G3-C12), and explored its anticancer activity against androgen-independent prostate cancer in vitro and in vivo. Compa …
In this study, we synthesized a novel G3-C12-mediated esterase-sensitive tumor-targeting polymeric prodrug of camptothecin (CPT), P(OEGMA-co …
Galectin-3 regulates p21 stability in human prostate cancer cells.
Wang Y, Balan V, Kho D, Hogan V, Nangia-Makker P, Raz A. Wang Y, et al. Oncogene. 2013 Oct 17;32(42):5058-65. doi: 10.1038/onc.2012.528. Epub 2012 Nov 19. Oncogene. 2013. PMID: 23160381 Free PMC article.
Galectin-3 (Gal-3) is a multifunctional protein involved in cancer through regulation of cell adhesion, cell growth, apoptosis and metastasis, while p21 (Cip1/WAF1) is a negative regulator of the cell cycle, involved in apoptosis, transcription, DNA re
Galectin-3 (Gal-3) is a multifunctional protein involved in cancer through regulation of cell adhesion, cell gro
The significance of galectin-3 as a new basal cell marker in prostate cancer.
Wang Y, Balan V, Gao X, Reddy PG, Kho D, Tait L, Raz A. Wang Y, et al. Cell Death Dis. 2013 Aug 1;4(8):e753. doi: 10.1038/cddis.2013.277. Cell Death Dis. 2013. PMID: 23907467 Free PMC article.
Galectin-3 (Gal-3) and androgen receptor (AR) have been reported to play important roles in the progression of prostate cancer, and their heterogeneous expressions might be associated with different cancer subtypes. ...Downregulation of G
Galectin-3 (Gal-3) and androgen receptor (AR) have been reported to play important roles in the progression of prost
84 results