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4,929 results

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Page 1
Differentiating visceral sensory ganglion organoids from induced pluripotent stem cells.
Ahn K, Park HS, Choi S, Lee H, Choi H, Hong SB, Han J, Han JW, Ahn J, Song J, Park K, Cha B, Kim M, Liu HW, Song H, Kim SJ, Chung S, Kim JI, Mook-Jung I. Ahn K, et al. Nat Methods. 2024 Nov;21(11):2135-2146. doi: 10.1038/s41592-024-02455-8. Epub 2024 Oct 22. Nat Methods. 2024. PMID: 39438735
The ability to generate visceral sensory neurons (VSN) from induced pluripotent stem (iPS) cells may help to gain insights into how the gut-nerve-brain axis is involved in neurological disorders. We established a protocol to differentiate human iPS-cell-deriv …
The ability to generate visceral sensory neurons (VSN) from induced pluripotent stem (iPS) cells may help to gain insights int …
Deciduous autologous tooth stem cells regenerate dental pulp after implantation into injured teeth.
Xuan K, Li B, Guo H, Sun W, Kou X, He X, Zhang Y, Sun J, Liu A, Liao L, Liu S, Liu W, Hu C, Shi S, Jin Y. Xuan K, et al. Sci Transl Med. 2018 Aug 22;10(455):eaaf3227. doi: 10.1126/scitranslmed.aaf3227. Sci Transl Med. 2018. PMID: 30135248 Clinical Trial.
We show that implantation of autologous tooth stem cells from deciduous teeth regenerated dental pulp with an odontoblast layer, blood vessels, and nerves in two animal models. ...We randomly allocated 30 patients to the human deciduous pulp stem cell
We show that implantation of autologous tooth stem cells from deciduous teeth regenerated dental pulp with an odontoblast laye …
Scalable generation of sensory neurons from human pluripotent stem cells.
Deng T, Jovanovic VM, Tristan CA, Weber C, Chu PH, Inman J, Ryu S, Jethmalani Y, Ferreira de Sousa J, Ormanoglu P, Twumasi P, Sen C, Shim J, Jayakar S, Bear Zhang HX, Jo S, Yu W, Voss TC, Simeonov A, Bean BP, Woolf CJ, Singeç I. Deng T, et al. Stem Cell Reports. 2023 Apr 11;18(4):1030-1047. doi: 10.1016/j.stemcr.2023.03.006. Stem Cell Reports. 2023. PMID: 37044067 Free PMC article.
Development of new non-addictive analgesics requires advanced strategies to differentiate human pluripotent stem cells (hPSCs) into relevant cell types. Following principles of developmental biology and translational applicability, here we developed an effici …
Development of new non-addictive analgesics requires advanced strategies to differentiate human pluripotent stem cells (hPSCs) …
Human PSC-derived organoids model sympathetic ganglion development and its functional crosstalk with the heart.
Liu Y, Zhu J, Lu X, Zhuang X, Wei J, Jiang L, Zhou W, Pang W, Yin Y, Chen Z, Cao Y, Zhang Q, Chen S, Chu S, Zhang X, Xiang Y. Liu Y, et al. Cell Stem Cell. 2026 Jan 8;33(1):29-43.e7. doi: 10.1016/j.stem.2025.11.003. Epub 2025 Dec 11. Cell Stem Cell. 2026. PMID: 41386226 Free article.
Here, we report a method to differentiate human pluripotent stem cells into 3D neural organoids that resemble peripheral sympathetic ganglia, producing both neurons and glial cells of the ganglia in a self-organized manner. We developed an organ …
Here, we report a method to differentiate human pluripotent stem cells into 3D neural organoids that resemble peripheral sympa …
Chemokinetics.
Miller RJ, Tran PB. Miller RJ, et al. Neuron. 2005 Sep 1;47(5):621-3. doi: 10.1016/j.neuron.2005.08.012. Neuron. 2005. PMID: 16129389 Free PMC article.
How do migrating neural progenitor cells and growing axons know where to go? In this issue of Neuron, two papers (Knaut et al. and Lieberam et al.) demonstrate that activation of Cxcr4 chemokine receptors by the chemokine SDF1/Cxcl12 can direct both of these tasks....
How do migrating neural progenitor cells and growing axons know where to go? In this issue of Neuron, two papers (Knaut et al. and Li …
[Erythropoietins].
Goll KH. Goll KH. Folia Haematol Int Mag Klin Morphol Blutforsch. 1974;101(5):771-5. Folia Haematol Int Mag Klin Morphol Blutforsch. 1974. PMID: 4140816 Review. German. No abstract available.
LncRNA-MEG3 protects against ganglion cell dysplasia in congenital intestinal atresia through directly regulating miR-211-5p/GDNF axis.
Xia Z, Ding D, Zhang N, Wang J, Yang H, Zhang D. Xia Z, et al. Biomed Pharmacother. 2019 Mar;111:436-442. doi: 10.1016/j.biopha.2018.11.089. Epub 2018 Dec 27. Biomed Pharmacother. 2019. PMID: 30594782 Free article.
The effects of MEG3 on the cell proliferation and apoptosis of isolated intestinal ganglion cells were detected with an MTT assay and flow cytometry, respectively. ...MEG3 promoted the differentiation of BMSCs into intestinal ganglion cells and …
The effects of MEG3 on the cell proliferation and apoptosis of isolated intestinal ganglion cells were detected with an …
Application of stem cell for the regeneration of spiral ganglion neurons.
Mohammadian F, Eatemadi A, Daraee H. Mohammadian F, et al. Cell Mol Biol (Noisy-le-grand). 2017 Jan 30;63(1):6-12. doi: 10.14715/cmb/2017.63.1.2. Cell Mol Biol (Noisy-le-grand). 2017. PMID: 28234627 Review.
In this review, we propose the regeneration of spiral ganglion neurons which is an interface neuron using human amniotic fluid mesenchymal stem cells (hAFMSCs), due to its high pluripotency potentials, this stem cell source can regenerate the sp …
In this review, we propose the regeneration of spiral ganglion neurons which is an interface neuron using human amniotic fluid mesenc …
Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons.
LeBlang CJ, Pazyra-Murphy MF, Silagi ES, Dasgupta S, Tsolias M, Miller T, Petrova V, Zhen S, Jovanovic VM, Castellano D, Gerrish K, Ormanoglu P, Tristan CA, Singeç I, Woolf CJ, Tasdemir-Yilmaz O, Segal RA. LeBlang CJ, et al. Stem Cell Reports. 2025 Oct 14;20(10):102639. doi: 10.1016/j.stemcr.2025.102639. Epub 2025 Sep 18. Stem Cell Reports. 2025. PMID: 40972585 Free PMC article.
Sensory neurons generated from induced pluripotent stem cells (idSNs) are used to model human peripheral neuropathies; however, current differentiation protocols produce cells with an embryonic phenotype. ...Here, we show that terminal differentiation of idSN …
Sensory neurons generated from induced pluripotent stem cells (idSNs) are used to model human peripheral neuropathies; however …
Cell-extracellular matrix versus cell-cell interactions during the development of the cochlear-vestibular ganglion.
Davies D. Davies D. J Neurosci Res. 2011 Sep;89(9):1375-87. doi: 10.1002/jnr.22664. Epub 2011 May 6. J Neurosci Res. 2011. PMID: 21557292
Cells destined to become the neurones of the cochlear-vestibular ganglion (CVG) originate within the otic epithelium. ...Importantly, neuroblasts retained the ability to segregate from the epithelium but remained compacted immediately adjacent to the originating tis
Cells destined to become the neurones of the cochlear-vestibular ganglion (CVG) originate within the otic epithelium. ...Impor
4,929 results