ganoderma - Search Results

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1

A Review of Ganoderma Triterpenoids and Their Bioactivities.

Galappaththi MCA, Patabendige NM, Premarathne BM, Hapuarachchi KK, Tibpromma S, Dai DQ, Suwannarach N, Rapior S, Karunarathna SC. Galappaththi MCA, et al. Biomolecules. 2022 Dec 22;13(1):24. doi: 10.3390/biom13010024. Biomolecules. 2022. PMID: 36671409 Free PMC article. Review.

For centuries, Ganoderma has been used as a traditional medicine in Asian countries to prevent and treat various diseases. Numerous publications are stating that Ganoderma species have a variety of beneficial medicinal properties, and investigations on different met …

For centuries, Ganoderma has been used as a traditional medicine in Asian countries to prevent and treat various diseases. Numerous p …

2

Health-Promoting of Polysaccharides Extracted from Ganoderma lucidum.

Seweryn E, Ziała A, Gamian A. Seweryn E, et al. Nutrients. 2021 Aug 7;13(8):2725. doi: 10.3390/nu13082725. Nutrients. 2021. PMID: 34444885 Free PMC article. Review.

Ganoderma lucidum is an important source of biologically active compounds. The pharmacologically active fraction of polysaccharides has antioxidant, immunomodulatory, antineurodegenerative and antidiabetic activities. In this review, we summarize the activity of Ganoder …

Ganoderma lucidum is an important source of biologically active compounds. The pharmacologically active fraction of polysaccharides h …

3

Polysaccharide of Ganoderma and Its Bioactivities.

Zhang J, Liu Y, Tang Q, Zhou S, Feng J, Chen H. Zhang J, et al. Adv Exp Med Biol. 2019;1181:107-134. doi: 10.1007/978-981-13-9867-4_4. Adv Exp Med Biol. 2019. PMID: 31677141 Review.

Ganoderma, named lingzhi in China, has been used for centuries as drug and nutraceutical to treat diseases. ...In addition, on the basis of a large number of studies on Ganoderma polysaccharides, we suggest that more clinical studies should be carried out so that …

Ganoderma, named lingzhi in China, has been used for centuries as drug and nutraceutical to treat diseases. ...In addition, on the ba …

4

Ganoderma immunomodulatory proteins: mushrooming functional FIPs.

Lin J, Chen H, Bai Y, Li S, Liang G, Fan T, Gao N, Wu X, Li H, Chen G, Gao Y, Fan J. Lin J, et al. Appl Microbiol Biotechnol. 2022 Apr;106(7):2367-2380. doi: 10.1007/s00253-022-11839-9. Epub 2022 Mar 29. Appl Microbiol Biotechnol. 2022. PMID: 35348851 Review.

Among all known FIPs, the firstly discovered FIP was isolated from Ganoderma lucidum, and most FIP members were from Ganoderma genus. Compared with other FIPs, Ganoderma FIPs possess some advantageous bioactivities, like stronger anti-tumor activity. ...Combi …

Among all known FIPs, the firstly discovered FIP was isolated from Ganoderma lucidum, and most FIP members were from Ganoderma …

5

The Phytochemistry of Ganoderma Species and their Medicinal Potentials.

Blundell R, Camilleri E, Baral B, Karpiński TM, Neza E, Atrooz OM. Blundell R, et al. Am J Chin Med. 2023;51(4):859-882. doi: 10.1142/S0192415X23500404. Epub 2023 Mar 31. Am J Chin Med. 2023. PMID: 36999543 Review.

The Ganoderma genus is known for its diverse use as a functional food and therapeutic agent. This fungus has over 428 species, with Ganoderma lucidum being the most studied. The Ganoderma species produce several secondary metabolites and bioactive compounds l …

The Ganoderma genus is known for its diverse use as a functional food and therapeutic agent. This fungus has over 428 species, with …

6

Chemical Components of Ganoderma.

Gong T, Yan R, Kang J, Chen R. Gong T, et al. Adv Exp Med Biol. 2019;1181:59-106. doi: 10.1007/978-981-13-9867-4_3. Adv Exp Med Biol. 2019. PMID: 31677140 Review.

So far, more than 20 species of Ganoderma (Lingzhi) fungi have been studied, including G. lucidum, G. sinense, G. japonicum, G. capense, G. australe, G. tsugae, G. applanatum, G. tropicus, G. boniense, G. duropora, G. resinaceum, G. theaecolum, G. cochlear, G. atrum, G. fo …

So far, more than 20 species of Ganoderma (Lingzhi) fungi have been studied, including G. lucidum, G. sinense, G. japonicum, G. capen …

7

Ganoderma sinense polysaccharide: An adjunctive drug used for cancer treatment.

Zhang Y, Jiang Y, Zhang M, Zhang L. Zhang Y, et al. Prog Mol Biol Transl Sci. 2019;163:165-177. doi: 10.1016/bs.pmbts.2019.02.008. Epub 2019 Mar 25. Prog Mol Biol Transl Sci. 2019. PMID: 31030747 Review.

Ganoderma sinense is one of well-known herb medicine and has been used for 2000 years in China. G. lucidum and G. sinense are two family members of Ganoderma, a genus of polypore fungi. In Chinese, "Lingzhi" is designated as G. lucidum or red "Lingzhi" whereas "Zizh …

Ganoderma sinense is one of well-known herb medicine and has been used for 2000 years in China. G. lucidum and G. sinense are two fam …

8

Ganoderma lucidum dry extract supplementation modulates T lymphocyte function in older women.

Iser-Bem PN, Lobato TB, Alecrim-Zeza AL, Dos Santos de Oliveira LC, Passos MEP, Manuel R, Diniz VLS, Correa IS, de Oliveira SP, Silva EBD, Almeida MM, Dias BB, Gritte RB, Levada-Pires AC, Masi LN, Hatanaka E, Pithon-Curi TC, Hirabara SM, Fabi JP, Curi R, Gorjao R. Iser-Bem PN, et al. Br J Nutr. 2024 Jul 28;132(2):130-140. doi: 10.1017/S0007114524001144. Epub 2024 May 27. Br J Nutr. 2024. PMID: 38800991 Clinical Trial.

However, studies on the physiological effects of Ganoderma lucidum dry extract food supplements are few. Therefore, here, we aimed to investigate the effects of Ganoderma lucidum dry extract food supplement on the lymphocyte function of older women. This was a doubl …

However, studies on the physiological effects of Ganoderma lucidum dry extract food supplements are few. Therefore, here, we aimed to …

9

Ganoderma (Lingzhi) in Traditional Chinese Medicine and Chinese Culture.

Lin Z. Lin Z. Adv Exp Med Biol. 2019;1181:1-13. doi: 10.1007/978-981-13-9867-4_1. Adv Exp Med Biol. 2019. PMID: 31677138 Review.

Shen Nong Ben Cao Jing (Shennong Materia Medica) and many other books in early Chinese history began to study, discuss, and report the scientific aspects of Ganoderma (Lingzhi) in respect to its categorization, habitat, bionomics, herbal nature, medication, etc. ...Present …

Shen Nong Ben Cao Jing (Shennong Materia Medica) and many other books in early Chinese history began to study, discuss, and report the scien …

10

Ganoderma.

Weber RW. Weber RW. Ann Allergy Asthma Immunol. 2009 Jul;103(1):A4, front cover. doi: 10.1016/s1081-1206(10)60133-0. Ann Allergy Asthma Immunol. 2009. PMID: 19663118 No abstract available.

11

A novel promising neuroprotective agent: Ganoderma lucidum polysaccharide.

Liu X, Yang L, Li G, Jiang Y, Zhang G, Ling J. Liu X, et al. Int J Biol Macromol. 2023 Feb 28;229:168-180. doi: 10.1016/j.ijbiomac.2022.12.276. Epub 2022 Dec 29. Int J Biol Macromol. 2023. PMID: 36587634 Review.

A traditional valuable medicine known as Ganoderma lucidum (GL) has a significant role to play in preserving health and treating diseases. Ganoderma lucidum polysaccharides (GLP) is one of the cardinal effective active ingredients of GL, which has a number of pharma …

A traditional valuable medicine known as Ganoderma lucidum (GL) has a significant role to play in preserving health and treating dise …

12

Ganoderma: insights into anticancer effects.

Kladar NV, Gavarić NS, Božin BN. Kladar NV, et al. Eur J Cancer Prev. 2016 Sep;25(5):462-71. doi: 10.1097/CEJ.0000000000000204. Eur J Cancer Prev. 2016. PMID: 26317382 Review.

The genus Ganoderma includes about 80 species growing on cut or rotten trees. The most commonly used species is Ganoderma ludicum. ...In-vivo studies have confirmed the anticancer potential and the antimetastatic effects of compounds originating from Ganoderma …

The genus Ganoderma includes about 80 species growing on cut or rotten trees. The most commonly used species is Ganoderma ludi …

13

Ganoderma proteins and their potential applications in cosmetics.

Li LD, Mao PW, Shao KD, Bai XH, Zhou XW. Li LD, et al. Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9239-9250. doi: 10.1007/s00253-019-10171-z. Epub 2019 Oct 29. Appl Microbiol Biotechnol. 2019. PMID: 31659419 Review.

Ganoderma have been regarded as a traditional source of natural bioactive compounds for centuries and have recently been exploited for potential components in the cosmetics industry. Besides Ganoderma polysaccharides and triterpenes, multiple proteins have been foun …

Ganoderma have been regarded as a traditional source of natural bioactive compounds for centuries and have recently been exploited fo …

14

Immunomodulating Effect of Ganoderma (Lingzhi) and Possible Mechanism.

Wang X, Lin Z. Wang X, et al. Adv Exp Med Biol. 2019;1182:1-37. doi: 10.1007/978-981-32-9421-9_1. Adv Exp Med Biol. 2019. PMID: 31777013 Review.

Ganoderma (Lingzhi) has been used for a long time in China to prevent and treat various diseases. Accumulated studies have demonstrated that the Ganoderma modulates immune function both in vivo and in vitro. The immunomodulating effects of Ganoderma were exte …

Ganoderma (Lingzhi) has been used for a long time in China to prevent and treat various diseases. Accumulated studies have demonstrat …

15

Ganoderma lucidum (Reishi) in cancer treatment.

Sliva D. Sliva D. Integr Cancer Ther. 2003 Dec;2(4):358-64. doi: 10.1177/1534735403259066. Integr Cancer Ther. 2003. PMID: 14713328 Free article. Review.

The popular edible mushroom Ganoderma lucidum (Reishi) has been widely used for the general promotion of health and longevity in Asian countries. ...However, because of the availability of Ganoderma lucidum from different sources, it is advisable to test its biologi …

The popular edible mushroom Ganoderma lucidum (Reishi) has been widely used for the general promotion of health and longevity in Asia …

16

Researches and Application of Ganoderma Spores Powder.

Xu J, Li P. Xu J, et al. Adv Exp Med Biol. 2019;1181:157-186. doi: 10.1007/978-981-13-9867-4_6. Adv Exp Med Biol. 2019. PMID: 31677143 Review.

Ganoderma lucidum spores (GLS) are the mature germ cells of Ganoderma lucidum. They have all the genetic substances and similar active components of Ganoderma lucidum. Similar to the fruiting body of Ganoderma lucidum, ganoderma spores powder ha …

Ganoderma lucidum spores (GLS) are the mature germ cells of Ganoderma lucidum. They have all the genetic substances and simila …

17

Development and Innovation of Ganoderma Industry and Products in China.

Li Z, Zhou J, Lin Z. Li Z, et al. Adv Exp Med Biol. 2019;1181:187-204. doi: 10.1007/978-981-13-9867-4_7. Adv Exp Med Biol. 2019. PMID: 31677144 Review.

Ganoderma (Lingzhi) has been used as a medicinal mushroom to promote health in China for more than 2000 years. The modern research and development of Ganoderma industry started from the 1950s, in which the successful cultivation of Ganoderma fruiting body and …

Ganoderma (Lingzhi) has been used as a medicinal mushroom to promote health in China for more than 2000 years. The modern research an …

18

Cellular and Molecular Mechanism of Ganoderma (Lingzhi) Against Tumor.

Sun Y, Sun L. Sun Y, et al. Adv Exp Med Biol. 2019;1182:79-118. doi: 10.1007/978-981-32-9421-9_3. Adv Exp Med Biol. 2019. PMID: 31777015 Review.

Intrinsic- and extrinsic-initiated apoptotic pathway in association with cell cycle arresting, telomerase inhibiting, autophagy, and oxidative stress is involved in the antiproliferative and apoptosis inductive activities of Ganoderma and its extracts. The inhibition of tu …

Intrinsic- and extrinsic-initiated apoptotic pathway in association with cell cycle arresting, telomerase inhibiting, autophagy, and oxidati …

19

Ganoderma - a therapeutic fungal biofactory.

Paterson RR. Paterson RR. Phytochemistry. 2006 Sep;67(18):1985-2001. doi: 10.1016/j.phytochem.2006.07.004. Epub 2006 Aug 14. Phytochemistry. 2006. PMID: 16905165 Review.

Ganoderma is a basidiomycete white rot fungus which has been used for medicinal purposes for centuries particularly in China, Japan and Korea. A great deal of work has been carried out on Ganoderma lucidum. The common names for preparations include Lingzhi, Munnerta …

Ganoderma is a basidiomycete white rot fungus which has been used for medicinal purposes for centuries particularly in China, Japan a …

20

Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells.

Ren L, Zhang J, Zhang T. Ren L, et al. Food Chem. 2021 Mar 15;340:127933. doi: 10.1016/j.foodchem.2020.127933. Epub 2020 Aug 26. Food Chem. 2021. PMID: 32882476 Review.

Polysaccharides from Ganoderma exhibit unique biological properties, including anti-tumor, anti-inflammatory, and immunomodulatory activities. Herein, the sources and structures of polysaccharides from Ganoderma were presented. This work also reviews the immunomodul …

Polysaccharides from Ganoderma exhibit unique biological properties, including anti-tumor, anti-inflammatory, and immunomodulatory ac …

21

Insights into Ganoderma fungi meroterpenoids opening a new era of racemic natural products in mushrooms.

Zhang JJ, Qin FY, Cheng YX. Zhang JJ, et al. Med Res Rev. 2024 May;44(3):1221-1266. doi: 10.1002/med.22006. Epub 2024 Jan 10. Med Res Rev. 2024. PMID: 38204140 Review.

Ganoderma meroterpenoids (GMs) containing 688 structures to date were discovered to have multiple remarkable biological activities. 65.6% of meroterpenoids featuring stereogenic centers from Ganoderma species are racemates. Further, GMs from different Ganoderma …

Ganoderma meroterpenoids (GMs) containing 688 structures to date were discovered to have multiple remarkable biological activities. 6 …

22

Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Diabetes.

Liu Q, Tie L. Liu Q, et al. Adv Exp Med Biol. 2019;1182:201-215. doi: 10.1007/978-981-32-9421-9_8. Adv Exp Med Biol. 2019. PMID: 31777020 Review.

As extracts from Ganoderma lucidum (G. lucidum, Lingzhi) have been reported to be an alternative adjuvant treatment for diabetes, numerous of work have been carried out on it. Among the many biologically active constituents of Ganoderma, polysaccharides, proteoglyca …

As extracts from Ganoderma lucidum (G. lucidum, Lingzhi) have been reported to be an alternative adjuvant treatment for diabetes, num …

23

Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Skin Diseases and Care.

Yin Z, Yang B, Ren H. Yin Z, et al. Adv Exp Med Biol. 2019;1182:311-321. doi: 10.1007/978-981-32-9421-9_14. Adv Exp Med Biol. 2019. PMID: 31777026 Review.

Traditionally, polysaccharides and ganoderic acids have been reported as the major functional metabolites of Ganoderma possessing antioxidant and anti-inflammatory functions. Based on our research and other studies, Ganoderma extracts, such as Ganoderma polys …

Traditionally, polysaccharides and ganoderic acids have been reported as the major functional metabolites of Ganoderma possessing ant …

24

Neuropharmacological Effect and Clinical Applications of Ganoderma (Lingzhi).

Cui X, Zhang Y. Cui X, et al. Adv Exp Med Biol. 2019;1182:143-157. doi: 10.1007/978-981-32-9421-9_5. Adv Exp Med Biol. 2019. PMID: 31777017 Review.

Ganoderma lucidum (G. lucidum, Lingzhi) is a kind of medical mushroom with various pharmacological compounds. ...Compared with its immunomodulatory effect, there are a few studies on the neuropharmacological actions of Ganoderma, and the mechanism has not been fully …

Ganoderma lucidum (G. lucidum, Lingzhi) is a kind of medical mushroom with various pharmacological compounds. ...Compared with its im …

25

Protective Effect of Ganoderma (Lingzhi) on Radiation and Chemotherapy.

Chen L, Abulizi A, Li M. Chen L, et al. Adv Exp Med Biol. 2019;1182:119-142. doi: 10.1007/978-981-32-9421-9_4. Adv Exp Med Biol. 2019. PMID: 31777016 Review.

This chapter reviewed the protective effects of Ganoderma (Lingzhi) on radiation and chemotherapy, including the preventive effects on myelosuppression, intestinal injury, nephrotoxicity, cardiovascular toxicity, and other side effects. Both basic researches and clinical s …

This chapter reviewed the protective effects of Ganoderma (Lingzhi) on radiation and chemotherapy, including the preventive effects o …

26

Classification, Biological Characteristics and Cultivations of Ganoderma.

Du Z, Dong CH, Wang K, Yao YJ. Du Z, et al. Adv Exp Med Biol. 2019;1181:15-58. doi: 10.1007/978-981-13-9867-4_2. Adv Exp Med Biol. 2019. PMID: 31677139 Review.

Species of Ganoderma (Ling-zhi) have been widely researched and cultivated due to their highly prized medicinal value, which is famous as a traditional Chinese medicine. The aims of this chapter are to (1) review the historical taxonomy of the family Ganodermataceae, (2) p …

Species of Ganoderma (Ling-zhi) have been widely researched and cultivated due to their highly prized medicinal value, which is famou …

27

Anti-aging Effect of Ganoderma (Lingzhi) with Health and Fitness.

Pan Y, Lin Z. Pan Y, et al. Adv Exp Med Biol. 2019;1182:299-309. doi: 10.1007/978-981-32-9421-9_13. Adv Exp Med Biol. 2019. PMID: 31777025 Review.

Although Ganoderma (Lingzhi in Chinese) has been used as an elixir for thousands of years, its anti-aging effects still need to be clarified. ...Ganoderma's anti-aging effect on human remains a mystery, and its potential mechanisms underlying anti-aging effect for i …

Although Ganoderma (Lingzhi in Chinese) has been used as an elixir for thousands of years, its anti-aging effects still need to be cl …

28

Anti-osteoporosis Effect of Ganoderma (Lingzhi) by Inhibition of Osteoclastogenesis.

Yang Y, Yang B. Yang Y, et al. Adv Exp Med Biol. 2019;1182:263-269. doi: 10.1007/978-981-32-9421-9_11. Adv Exp Med Biol. 2019. PMID: 31777023 Review.

The anti-osteoporosis effect of Ganoderma lucidum (G. lucidum, Lingzhi) is closely associated with inhibition of osteoclastogenesis in the charge of osteoclasts. This article reviewed the anti-osteoporosis effect of Ganoderma and its active components, including a k …

The anti-osteoporosis effect of Ganoderma lucidum (G. lucidum, Lingzhi) is closely associated with inhibition of osteoclastogenesis i …

29

Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Liver Injury.

Qiu Z, Zhong D, Yang B. Qiu Z, et al. Adv Exp Med Biol. 2019;1182:217-242. doi: 10.1007/978-981-32-9421-9_9. Adv Exp Med Biol. 2019. PMID: 31777021 Review.

Ganoderma lucidum (G. lucidum, Lingzhi) has a wide range of hepatoprotective effects. Its bioactive substances include triterpenoids, polysaccharides, sterols, steroids, peptides, and other bioactive ingredients. ...

Ganoderma lucidum (G. lucidum, Lingzhi) has a wide range of hepatoprotective effects. Its bioactive substances include triterpenoids, …

30

Ganoderma formosanum Exopolysaccharides Inhibit Tumor Growth via Immunomodulation.

Kuo HC, Liu YW, Lum CC, Hsu KD, Lin SP, Hsieh CW, Lin HW, Lu TY, Cheng KC. Kuo HC, et al. Int J Mol Sci. 2021 Oct 19;22(20):11251. doi: 10.3390/ijms222011251. Int J Mol Sci. 2021. PMID: 34681911 Free PMC article.

Ganoderma formosanum (GF) is a medicinal mushroom endemic to Taiwan. Previous research established the optimal culture conditions to produce exopolysaccharide rich in beta-glucan (GF-EPS) from submerged fermentation of GF. ...

Ganoderma formosanum (GF) is a medicinal mushroom endemic to Taiwan. Previous research established the optimal culture conditions to …

31

From 2000years of Ganoderma lucidum to recent developments in nutraceuticals.

Bishop KS, Kao CH, Xu Y, Glucina MP, Paterson RR, Ferguson LR. Bishop KS, et al. Phytochemistry. 2015 Jun;114:56-65. doi: 10.1016/j.phytochem.2015.02.015. Epub 2015 Mar 17. Phytochemistry. 2015. PMID: 25794896 Review.

Medicinal mushrooms have been used for centuries as nutraceuticals to improve health and to treat numerous chronic and infectious diseases. One such mushroom is Ganoderma lucidum, commonly known as Lingzhi, a species revered as a medicinal mushroom for treating assorted di …

Medicinal mushrooms have been used for centuries as nutraceuticals to improve health and to treat numerous chronic and infectious diseases. …

32

A review of Ganoderma lucidum polysaccharides: Health benefit, structure-activity relationship, modification, and nanoparticle encapsulation.

Kou F, Ge Y, Wang W, Mei Y, Cao L, Wei X, Xiao H, Wu X. Kou F, et al. Int J Biol Macromol. 2023 Jul 15;243:125199. doi: 10.1016/j.ijbiomac.2023.125199. Epub 2023 Jun 6. Int J Biol Macromol. 2023. PMID: 37285888 Review.

Ganoderma lucidum polysaccharides possess unique functional properties. Various processing technologies have been used to produce and modify G. lucidum polysaccharides to improve their yield and utilization. ...

Ganoderma lucidum polysaccharides possess unique functional properties. Various processing technologies have been used to produce and …

33

Molecular defense response of oil palm to Ganoderma infection.

Ho CL, Tan YC. Ho CL, et al. Phytochemistry. 2015 Jun;114:168-77. doi: 10.1016/j.phytochem.2014.10.016. Epub 2014 Nov 12. Phytochemistry. 2015. PMID: 25457484 Review.

Basal stem rot (BSR) of oil palm roots is due to the invasion of fungal mycelia of Ganoderma species which spreads to the bole of the stem. In addition to root contact, BSR can also spread by airborne basidiospores. ...The transmission and mode of action of Ganoderma …

Basal stem rot (BSR) of oil palm roots is due to the invasion of fungal mycelia of Ganoderma species which spreads to the bole of the …

34

Traditional to technological advancements in Ganoderma detection methods in oil palm.

Amrutha Lakshmi M, B R A, Manyam P, Javeedvali S, Khan AS, Palnam DW, Kandan A. Amrutha Lakshmi M, et al. Folia Microbiol (Praha). 2024 Oct;69(5):953-973. doi: 10.1007/s12223-024-01177-w. Epub 2024 Jul 8. Folia Microbiol (Praha). 2024. PMID: 38976188 Review.

Ganoderma sp., the fungal agent causing basal stem rot (BSR), poses a severe threat to global oil palm production. ...Recent advancements, including real-time PCR, biosensors, and isothermal amplification methods, facilitate accurate, specific, and sensitive Ganoderma …

Ganoderma sp., the fungal agent causing basal stem rot (BSR), poses a severe threat to global oil palm production. ...Recent advancem …

35

Pharmacological effects of natural Ganoderma and its extracts on neurological diseases: A comprehensive review.

Zhao C, Zhang C, Xing Z, Ahmad Z, Li JS, Chang MW. Zhao C, et al. Int J Biol Macromol. 2019 Jan;121:1160-1178. doi: 10.1016/j.ijbiomac.2018.10.076. Epub 2018 Oct 18. Int J Biol Macromol. 2019. PMID: 30342128 Review.

Ganoderma, has been used for clinical applications for thousands of years as a highly-nutritious and significantly-effective medicinal herb. The active components and efficacy of Ganoderma are constantly being explored and supplemented every year. In recent years, m …

Ganoderma, has been used for clinical applications for thousands of years as a highly-nutritious and significantly-effective medicina …

36

Ganoderma pfeifferi--A European relative of Ganoderma lucidum.

Lindequist U, Jülich WD, Witt S. Lindequist U, et al. Phytochemistry. 2015 Jun;114:102-8. doi: 10.1016/j.phytochem.2015.02.018. Epub 2015 Mar 25. Phytochemistry. 2015. PMID: 25817834 Review.

In contrast to well-studied and broadly used Ganoderma species, such as Ganoderma lucidum and Ganoderma applanatum, knowledge regarding Ganoderma pfeifferi is very limited. ...

In contrast to well-studied and broadly used Ganoderma species, such as Ganoderma lucidum and Ganoderma applanatum, kno …

37

A review update on Ganoderma species: etiology and management approaches.

Thakur P, Khanal S, Tapwal A, Sharma N, Chauhan P, Thakur TS, Kumar D, Verma R. Thakur P, et al. Antonie Van Leeuwenhoek. 2025 Nov 1;118(12):185. doi: 10.1007/s10482-025-02193-7. Antonie Van Leeuwenhoek. 2025. PMID: 41176521 Review.

Ganoderma is a diversified genus of wood decaying fungi known to cause diseases such as stem, butt, and root rot in economically significant trees and perennial crops. ...The distinctive features observed across different Ganoderma species render them valuable for n …

Ganoderma is a diversified genus of wood decaying fungi known to cause diseases such as stem, butt, and root rot in economically sign …

38

Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity of Ganoderma meroterpenoids.

Peng XR, Unsicker SB, Gershenzon J, Qiu MH. Peng XR, et al. Nat Prod Rep. 2023 Aug 16;40(8):1354-1392. doi: 10.1039/d3np00006k. Nat Prod Rep. 2023. PMID: 37051770 Review.

Covering: 2018 to 2022Meroterpenoids found in fungal species of the genus Ganoderma and known as Ganoderma meroterpenoids (GMs) are substances composed of a 1,2,4-trisubstituted benzene and a polyunsaturated side chain. ...We propose for the first time a plausible b …

Covering: 2018 to 2022Meroterpenoids found in fungal species of the genus Ganoderma and known as Ganoderma meroterpenoids (GMs …

39

Ganoderma lucidum-Derived Meroterpenoids Show Anti-Inflammatory Activity In Vitro.

Liu YY, Cai D, Tang XP, Cheng YX. Liu YY, et al. Molecules. 2024 Mar 5;29(5):1149. doi: 10.3390/molecules29051149. Molecules. 2024. PMID: 38474661 Free PMC article.

Ganoderma lucidum, known as the "herb of spiritual potency", is used for the treatment and prevention of various diseases, but the responsible constituents for its therapeutic effects are largely unknown. ...The current study will aid in enriching the structural and biolog …

Ganoderma lucidum, known as the "herb of spiritual potency", is used for the treatment and prevention of various diseases, but the re …

40

Accessing biological actions of Ganoderma secondary metabolites by in silico profiling.

Grienke U, Kaserer T, Pfluger F, Mair CE, Langer T, Schuster D, Rollinger JM. Grienke U, et al. Phytochemistry. 2015 Jun;114:114-24. doi: 10.1016/j.phytochem.2014.10.010. Epub 2014 Nov 6. Phytochemistry. 2015. PMID: 25457486 Free PMC article. Review.

However, due to this remarkable amount of information, a rationalization of the individual Ganoderma constituents to biological actions on a molecular level is quite challenging. ...Accordingly, this study discloses putative ligand target interactions for a plethora of …

However, due to this remarkable amount of information, a rationalization of the individual Ganoderma constituents to biological actio …

41

Liposoluble compounds from Ganoderma lipsiense grown on solid red rice medium with antiparasitic and antibacterial properties.

Costa TM, Lenzi J, Paganelli CJ, Filho HHDS, Alberton MD, Tavares LBB, de Oliveira D. Costa TM, et al. Biotechnol Appl Biochem. 2020 Mar;67(2):180-185. doi: 10.1002/bab.1851. Epub 2019 Nov 27. Biotechnol Appl Biochem. 2020. PMID: 31710143 Review.

The present study aimed to identify liposoluble molecules produced by Ganoderma lipsiense grown in red rice medium using solid-state fermentation (SSF) techniques, and to investigate the antigiardial and antibacterial activities potential of extracts in vitro. ...

The present study aimed to identify liposoluble molecules produced by Ganoderma lipsiense grown in red rice medium using solid-state …

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Antitumor Effect of Ganoderma (Lingzhi) Mediated by Immunological Mechanism and Its Clinical Application.

Lin Z, Sun L. Lin Z, et al. Adv Exp Med Biol. 2019;1182:39-77. doi: 10.1007/978-981-32-9421-9_2. Adv Exp Med Biol. 2019. PMID: 31777014 Review.

The antitumor effect of Ganoderma (Lingzhi) is closely related to immunoregulation. Based on our research and other references, this article discussed the antitumor effect of Ganoderma mediated by immunological mechanism, including promoting the function of mononucl …

The antitumor effect of Ganoderma (Lingzhi) is closely related to immunoregulation. Based on our research and other references, this …

43

Characterizing novel anti-oncogenic triterpenoids from ganoderma.

Li X, Xie Y, Yang BB. Li X, et al. Cell Cycle. 2018;17(5):527-528. doi: 10.1080/15384101.2017.1315493. Cell Cycle. 2018. PMID: 28402700 Free PMC article. No abstract available.

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Genome analysis of medicinal Ganoderma spp. with plant-pathogenic and saprotrophic life-styles.

Kües U, Nelson DR, Liu C, Yu GJ, Zhang J, Li J, Wang XC, Sun H. Kües U, et al. Phytochemistry. 2015 Jun;114:18-37. doi: 10.1016/j.phytochem.2014.11.019. Epub 2015 Feb 11. Phytochemistry. 2015. PMID: 25682509 Review.

Ganoderma is a fungal genus belonging to the Ganodermataceae family and Polyporales order. ...In addition to the nuclear genome, two mitochondrial genomes for Ganoderma species have also been reported. Complementing genome analysis, four transcriptome studies on var …

Ganoderma is a fungal genus belonging to the Ganodermataceae family and Polyporales order. ...In addition to the nuclear genome, two …

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Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities.

Ferreira IC, Heleno SA, Reis FS, Stojkovic D, Queiroz MJ, Vasconcelos MH, Sokovic M. Ferreira IC, et al. Phytochemistry. 2015 Jun;114:38-55. doi: 10.1016/j.phytochem.2014.10.011. Epub 2014 Nov 5. Phytochemistry. 2015. PMID: 25457487 Review.

Ganoderma genus comprises one of the most commonly studied species worldwide, Ganoderma lucidum. However, other Ganoderma species have been also reported as important sources of bioactive compounds. Polysaccharides are important contributors to the medicinal …

Ganoderma genus comprises one of the most commonly studied species worldwide, Ganoderma lucidum. However, other Ganoderma …

46

A Comprehensive Review on the Chemical Composition, Pharmacology and Clinical Applications of Ganoderma.

Liu C, Song X, Li Y, Ding C, Li X, Dan L, Xu H, Zhang D. Liu C, et al. Am J Chin Med. 2023;51(8):1983-2040. doi: 10.1142/S0192415X23500878. Epub 2023 Oct 31. Am J Chin Med. 2023. PMID: 37903715 Review.

Ganoderma is the dried fruiting bodiy of Ganoderma lucidum (Leyss.ex Fr.) Karst. or Ganoderma sinense Zhao, Xu et Zhang, belonging to the family Polyporaceae, which grows mainly in tropical, subtropical, and temperate regions. ...Modern pharmacological studie …

Ganoderma is the dried fruiting bodiy of Ganoderma lucidum (Leyss.ex Fr.) Karst. or Ganoderma sinense Zhao, Xu et Zhang …

47

From nutraceutical to clinical trial: frontiers in Ganoderma development.

Hsu KD, Cheng KC. Hsu KD, et al. Appl Microbiol Biotechnol. 2018 Nov;102(21):9037-9051. doi: 10.1007/s00253-018-9326-5. Epub 2018 Sep 4. Appl Microbiol Biotechnol. 2018. PMID: 30182215 Review.

Ganoderma spp. are medical mushrooms with various pharmacological compounds which are regarded as a nutraceutical for improving health and treating diseases. ...However, since these medical fungi are rare in natural environment, and that the cost of cultivation of fruiting …

Ganoderma spp. are medical mushrooms with various pharmacological compounds which are regarded as a nutraceutical for improving healt …

48

Meroterpenoids and alkaloids from Ganoderma australe.

Zhang JJ, Dong Y, Qin FY, Yan YM, Cheng YX. Zhang JJ, et al. Nat Prod Res. 2021 Oct;35(19):3226-3232. doi: 10.1080/14786419.2019.1693565. Epub 2019 Nov 19. Nat Prod Res. 2021. PMID: 31741407

Two new mertoterpenoids, australins A (1) and B (2), and a new alkaloid, australine (4), together with five known compounds (3, 5-8) were isolated from the fruiting bodies of Ganoderma australe. Their structures including absolute configurations were assigned by using spec …

Two new mertoterpenoids, australins A (1) and B (2), and a new alkaloid, australine (4), together with five known compounds (3, 5-8) were is …

49

Antiinflammatory lanostane triterpenoids from Ganoderma lucidum.

Koo MH, Chae HJ, Lee JH, Suh SS, Youn UJ. Koo MH, et al. Nat Prod Res. 2021 Nov;35(22):4295-4302. doi: 10.1080/14786419.2019.1705815. Epub 2019 Dec 24. Nat Prod Res. 2021. PMID: 31872776

Phytochemical and biological studies of the methanolic extracts from Ganoderma lucidum (Polyporaceae) have led to the identification and isolation of a new lanostane triterpenoid, ganosidone A (1), and its eight known derivatives (2-9). ...

Phytochemical and biological studies of the methanolic extracts from Ganoderma lucidum (Polyporaceae) have led to the identification …

50

Ganoderma diseases of perennial crops in India--an overview.

Sankaran KV, Bridge PD, Gokulapalan C. Sankaran KV, et al. Mycopathologia. 2005 Jan;159(1):143-52. doi: 10.1007/s11046-004-4437-1. Mycopathologia. 2005. PMID: 15750747 Review.

The species of Ganoderma recorded from India as causing diseases of perennial crops are listed, and their host range and taxonomy discussed. ...Ganoderma diseases have been recorded on 144 hosts in India, the major pathogens being G. lucidum and G. applanatum. ...

The species of Ganoderma recorded from India as causing diseases of perennial crops are listed, and their host range and taxonomy dis …

51

Cytotoxic ergostane-type steroids from Ganoderma lingzhi.

Yu JH, Yu SJ, Liu KL, Wang C, Liu C, Sun JY, Zhang H. Yu JH, et al. Steroids. 2021 Jan;165:108767. doi: 10.1016/j.steroids.2020.108767. Epub 2020 Nov 16. Steroids. 2021. PMID: 33212127

Two new ergostane-type steroids (1 and 2) have been isolated from the fruiting body of a medicinal macro fungus Ganoderma lingzhi. The structures including the absolute configurations of them were elucidated by a combination of different spectroscopic analyses especially ( …

Two new ergostane-type steroids (1 and 2) have been isolated from the fruiting body of a medicinal macro fungus Ganoderma lingzhi. Th …

52

Triterpene-farnesyl hydroquinone conjugates from Ganoderma calidophilum.

Zhang LJ, Xie Y, Wang YQ, Xu YY, Mei RQ. Zhang LJ, et al. Nat Prod Res. 2021 Jul;35(13):2199-2204. doi: 10.1080/14786419.2019.1667346. Epub 2019 Sep 23. Nat Prod Res. 2021. PMID: 31542946

Two new lanostane-type triterpenoids characterized with farnesyl hydroquinone moieties, ganocalidoins A (1) and B (2), were isolated from the fruiting body of Ganoderma calidophilum, together with two known tripterpenes (3-4). The structures of compounds 1 and 2 were deter …

Two new lanostane-type triterpenoids characterized with farnesyl hydroquinone moieties, ganocalidoins A (1) and B (2), were isolated from th …

53

Quantitative Analysis of Components in Ganoderma.

Chen R, Kang J. Chen R, et al. Adv Exp Med Biol. 2019;1181:135-155. doi: 10.1007/978-981-13-9867-4_5. Adv Exp Med Biol. 2019. PMID: 31677142

The components in Ganoderma, including triterpenes, polysaccharides, nucleosides or nucleobases, steroids, and ergothioneine, were quantitatively analyzed. ...

The components in Ganoderma, including triterpenes, polysaccharides, nucleosides or nucleobases, steroids, and ergothioneine, were qu …

54

Ganoderma oerstedii (Fr.) murrill (higher Basidiomycetes), a tree parasite species in Mexico: taxonomic description, rDNA study, and review of its medical applications.

Mendoza G, Guzman G, Ramirez-Guillen F, Luna M, Trigos A. Mendoza G, et al. Int J Med Mushrooms. 2011;13(6):545-52. doi: 10.1615/intjmedmushr.v13.i6.60. Int J Med Mushrooms. 2011. PMID: 22181842 Review.

We present a description of macro- and microscopic taxonomical features of a medicinal mushroom, Ganoderma oerstedii, based on Mexican specimens from the states of Chiapas, Morelos, Sinaloa, and Veracruz, and discuss its relationships with species of the G. lucidum complex …

We present a description of macro- and microscopic taxonomical features of a medicinal mushroom, Ganoderma oerstedii, based on Mexica …

55

Semisynthetic modifications of antitubercular lanostane triterpenoids from Ganoderma.

Chinthanom P, Vichai V, Dokladda K, Sappan M, Thongpanchang C, Isaka M. Chinthanom P, et al. J Antibiot (Tokyo). 2021 Jul;74(7):435-442. doi: 10.1038/s41429-021-00422-5. Epub 2021 May 12. J Antibiot (Tokyo). 2021. PMID: 33981028 Free PMC article.

Antitubercular lanostane triterpenoids isolated from mycelial cultures of the basidiomycete Ganoderma australe were structurally modified by semisynthesis. One of the synthetic compounds, named GA003 (9), showed more potent activity against Mycobacterium tuberculosis H37Ra …

Antitubercular lanostane triterpenoids isolated from mycelial cultures of the basidiomycete Ganoderma australe were structurally modi …

56

Enzymatic Glycosylation of Ganoderma Terpenoid via Bacterial Glycosyltransferases and Glycoside Hydrolases.

Chang TS, Wu JY, Ding HY, Wang TY. Chang TS, et al. Biomolecules. 2025 May 1;15(5):655. doi: 10.3390/biom15050655. Biomolecules. 2025. PMID: 40427548 Free PMC article. Review.

This review explored the role of two primary enzyme classes-glycosyltransferases (GTs) and glycoside hydrolases (GHs, glycosidases)-in catalyzing the glycosylation of natural products, with a specific focus on Ganoderma triterpenoids. While GTs typically use activated suga …

This review explored the role of two primary enzyme classes-glycosyltransferases (GTs) and glycoside hydrolases (GHs, glycosidases)-in catal …

57

Prospects of Ganoderma polysaccharides: Structural features, structure-function relationships, and quality evaluation.

Deng Y, Lei J, Luo X, Wang SP, Tan HM, Zhang JY, Wu DT. Deng Y, et al. Int J Biol Macromol. 2025 May;309(Pt 2):142836. doi: 10.1016/j.ijbiomac.2025.142836. Epub 2025 Apr 3. Int J Biol Macromol. 2025. PMID: 40187470 Review.

Polysaccharides, the primary bioactive compounds found in Ganoderma, are responsible for a multitude of biological activities. The bioactivity of Ganoderma polysaccharides (GPs) closely correlates to their physicochemical properties. ...

Polysaccharides, the primary bioactive compounds found in Ganoderma, are responsible for a multitude of biological activities. The bi …

58

Biosynthesis, Gene Expression, and Pharmacological Properties of Triterpenoids of Ganoderma Species (Agaricomycetes): A Review.

Angulo-Sanchez LT, López-Peña D, Torres-Moreno H, Gutiérrez A, Gaitán-Hernández R, Esqueda M. Angulo-Sanchez LT, et al. Int J Med Mushrooms. 2022;24(6):1-17. doi: 10.1615/IntJMedMushrooms.2022044016. Int J Med Mushrooms. 2022. PMID: 35695634 Review.

For more than 6 millennia, Ganoderma species have been used in traditional Asian medicine due to their health benefits. Ganoderma synthesizes several compounds with biological activity, including lanostane-type triterpenoids like ganoderic acids (GAs), lucidones, an …

For more than 6 millennia, Ganoderma species have been used in traditional Asian medicine due to their health benefits. Ganoderma …

59

Applied modern biotechnology for cultivation of Ganoderma and development of their products.

Zhou XW, Su KQ, Zhang YM. Zhou XW, et al. Appl Microbiol Biotechnol. 2012 Feb;93(3):941-63. doi: 10.1007/s00253-011-3780-7. Epub 2011 Dec 15. Appl Microbiol Biotechnol. 2012. PMID: 22170106 Free PMC article. Review.

In order to analyze the current status of Ganoderma products, the detailed process of cultivation of Ganoderma spp. and development of their products are restated in this review article. These include the breeding, cultivating, extracting bioactive component, and pr …

In order to analyze the current status of Ganoderma products, the detailed process of cultivation of Ganoderma spp. and develo …

60

Revision of Ganoderma species associated with stem rot of coconut palm.

Vinjusha N, Arun Kumar TK. Vinjusha N, et al. Mycologia. 2022 Jan-Feb;114(1):157-174. doi: 10.1080/00275514.2021.1974724. Epub 2021 Nov 19. Mycologia. 2022. PMID: 34797203

Morphological and molecular investigations revealed that these specimens were distinct from all the Ganoderma species so far identified and reported from coconut. Although with a close morphological resemblance to many Ganoderma species collected from palms, they ex …

Morphological and molecular investigations revealed that these specimens were distinct from all the Ganoderma species so far identifi …

61

Diseases caused by Ganoderma spp. on perennial crops in Pakistan.

Nasir N. Nasir N. Mycopathologia. 2005 Jan;159(1):119-21. doi: 10.1007/s11046-004-4433-5. Mycopathologia. 2005. PMID: 15750743 Review.

Ganoderma applanatum (Pres. Wallr) Pat. and G. lucidum (Leyss. ex Fr.) Karst attack species of Pinus, Dalbergia, Artocarpus, Morus, Cedrus, Melia, Quercus, Populus and other trees in Pakistan causing stem, butt and root rot diseases. ...

Ganoderma applanatum (Pres. Wallr) Pat. and G. lucidum (Leyss. ex Fr.) Karst attack species of Pinus, Dalbergia, Artocarpus, Morus, C …

62

Secondary metabolites from Ganoderma.

Baby S, Johnson AJ, Govindan B. Baby S, et al. Phytochemistry. 2015 Jun;114:66-101. doi: 10.1016/j.phytochem.2015.03.010. Epub 2015 May 11. Phytochemistry. 2015. PMID: 25975187

Ganoderma is a genus of medicinal mushrooms. This review deals with secondary metabolites isolated from Ganoderma and their biological significance. ...Ganoderma applanatum, Ganoderma colossum, Ganoderma sinense, Ganoderma cochlear, Ga …

Ganoderma is a genus of medicinal mushrooms. This review deals with secondary metabolites isolated from Ganoderma and their bi …

63

Ganoderma carnosum and Ganoderma pfeifferi: Metal concentration, phenolic content, and biological activity.

Yalcin OU, Sarikurkcu C, Cengiz M, Gungor H, Ćavar Zeljković S. Yalcin OU, et al. Mycologia. 2020 Jan-Feb;112(1):1-8. doi: 10.1080/00275514.2019.1689748. Epub 2020 Jan 3. Mycologia. 2020. PMID: 31900077

Medicinal Ganoderma mushrooms have long tradition in Asia, and recently they began to be consumed in Europe as well. ...Overall results indicate that these two Ganoderma species have strong potential to be used for medicinal purposes....

Medicinal Ganoderma mushrooms have long tradition in Asia, and recently they began to be consumed in Europe as well. ...Overall resul …

64

Editorial for the special issue on Ganoderma.

Paterson RR, Lima N. Paterson RR, et al. Phytochemistry. 2015 Jun;114:5-6. doi: 10.1016/j.phytochem.2015.04.008. Epub 2015 May 12. Phytochemistry. 2015. PMID: 25979139 No abstract available.

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Bioactive compounds of Ganoderma species: molecular mechanisms and therapeutic potential in cancer and metabolic disorders.

Sharma A, Suvedi D, Kumar A, Khanal S, Verma R, Kumar D, Kumar D, Tapwal A, Kumar V, Peter L. Sharma A, et al. World J Microbiol Biotechnol. 2025 Dec 4;41(12):497. doi: 10.1007/s11274-025-04687-y. World J Microbiol Biotechnol. 2025. PMID: 41342967 Review.

Special emphasis is given to Ganoderma leucocontextum, a species identified in Tibet in 2015, with notable pharmacological properties. ...This review underlines the microbial biotechnological potential of Ganoderma species against cancer and metabolic disorders, adv …

Special emphasis is given to Ganoderma leucocontextum, a species identified in Tibet in 2015, with notable pharmacological properties …

66

Ganoderma tsugae suppresses the proliferation of endometrial carcinoma cells via Akt signaling pathway.

Tsai YT, Kuo PH, Kuo HP, Hsu CY, Lee YJ, Kuo CL, Liu JY, Lee SL, Kao MC. Tsai YT, et al. Environ Toxicol. 2021 Mar;36(3):320-327. doi: 10.1002/tox.23037. Epub 2020 Oct 12. Environ Toxicol. 2021. PMID: 33044769

Ganoderma is one of the common medicinal mushrooms in traditional Chinese medicine. Previous researches have unveiled the multifaceted biological activity of Ganoderma extract. ...This study aimed to demonstrate the first study of Ganoderma on treating endome …

Ganoderma is one of the common medicinal mushrooms in traditional Chinese medicine. Previous researches have unveiled the multifacete …

67

Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action.

Karunarathna SC, Patabendige NM, Hapuarachchi KK, Promputtha I. Karunarathna SC, et al. Front Cell Infect Microbiol. 2025 Jul 18;15:1535246. doi: 10.3389/fcimb.2025.1535246. eCollection 2025. Front Cell Infect Microbiol. 2025. PMID: 40756033 Free PMC article. Review.

Ganoderma, a well-known medicinal mushroom, has garnered attention for its broad therapeutic properties, particularly its potent antimicrobial activities. This review focuses on the mechanisms of action and bioactive compounds responsible for the ability of Ganoderma …

Ganoderma, a well-known medicinal mushroom, has garnered attention for its broad therapeutic properties, particularly its potent anti …

68

The Pharmacological Rationales and Molecular Mechanisms of Ganoderma lucidum Polysaccharides for the Therapeutic Applications of Multiple Diseases.

Luo H, Tan D, Peng B, Zhang S, Vong CT, Yang Z, Wang Y, Lin Z. Luo H, et al. Am J Chin Med. 2022;50(1):53-90. doi: 10.1142/S0192415X22500033. Epub 2021 Dec 28. Am J Chin Med. 2022. PMID: 34963429 Review.

As a versatile Chinese herb, Ganoderma lucidum (Leyss. ex Fr.) Karst (G. lucidum) has been applied to treat multiple diseases in clinics and improve the quality of life of patients. ...In this review, we used the keywords of "Ganoderma lucidum polysaccharides" and " …

As a versatile Chinese herb, Ganoderma lucidum (Leyss. ex Fr.) Karst (G. lucidum) has been applied to treat multiple diseases in clin …

69

Renoprotective meroterpenoids from the fungus Ganoderma cochlear.

Wang XL, Wu ZH, Di L, Zhou FJ, Yan YM, Cheng YX. Wang XL, et al. Fitoterapia. 2019 Jan;132:88-93. doi: 10.1016/j.fitote.2018.12.002. Epub 2018 Dec 4. Fitoterapia. 2019. PMID: 30521858

Nine multifarious new meroterpenoids, cochlearols E-M (1-9), along with seven known meroterpenoids 10-16, were isolated from the fruiting bodies of Ganoderma cochlear. Racemic 1, 6-8, 10 and 13 were separated by chiral HPLC. The structures were elucidated based on detailed …

Nine multifarious new meroterpenoids, cochlearols E-M (1-9), along with seven known meroterpenoids 10-16, were isolated from the fruiting bo …

70

Natural Compounds and Health Benefits of Ganoderma capense.

Liu L, Shi X, Jia L, Wang R, Liu C. Liu L, et al. Molecules. 2025 May 21;30(10):2250. doi: 10.3390/molecules30102250. Molecules. 2025. PMID: 40430421 Free PMC article. Review.

Ganoderma capense, a member of the Ganoderma genus within the Polyporaceae family, has long been recognized for its high nutritional value and extensive use in traditional medicine. ...

Ganoderma capense, a member of the Ganoderma genus within the Polyporaceae family, has long been recognized for its high nutri …

71

A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp.

Xia Q, Zhang H, Sun X, Zhao H, Wu L, Zhu D, Yang G, Shao Y, Zhang X, Mao X, Zhang L, She G. Xia Q, et al. Molecules. 2014 Oct 30;19(11):17478-535. doi: 10.3390/molecules191117478. Molecules. 2014. PMID: 25361420 Free PMC article. Review.

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. ...This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the liter …

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularl …

72

Meroterpenoids from Ganoderma petchii inhibiting migration of triple negative breast cancer cells.

Zhang JJ, Guo PX, Yang ZH, Cai D, Dai WF, Lu Q, Cheng YX. Zhang JJ, et al. Fitoterapia. 2023 Jun;167:105505. doi: 10.1016/j.fitote.2023.105505. Epub 2023 Apr 7. Fitoterapia. 2023. PMID: 37031876

Ganoderpetchoids A-E and (-)-dayaolingzhiol H, six undescribed meroterpenoids, were isolated from Ganoderma petchii. Their structures including the relative configurations were identified by means of spectroscopic methods and (13)C NMR calculations. ...

Ganoderpetchoids A-E and (-)-dayaolingzhiol H, six undescribed meroterpenoids, were isolated from Ganoderma petchii. Their structures …

73

Natural products of the medicinal fungus Ganoderma lucidum: occurrence, biological activities, and pharmacological functions.

Shiao MS. Shiao MS. Chem Rec. 2003;3(3):172-80. doi: 10.1002/tcr.10058. Chem Rec. 2003. PMID: 12900937 Review.

Among the Ganoderma triterpenoids, many pairs of C-3 alpha/beta stereoisomers and C-3/C-15 positional isomers have been identified. ...A combination treatment of lovastatin and Ganoderma triterpenoids in animal studies has exhibited a potential anticancer effect....

Among the Ganoderma triterpenoids, many pairs of C-3 alpha/beta stereoisomers and C-3/C-15 positional isomers have been identified. . …

74

Renoprotective phenolic meroterpenoids from the mushroom Ganoderma cochlear.

Wang XL, Wu ZH, Di L, Zhou FJ, Yan YM, Cheng YX. Wang XL, et al. Phytochemistry. 2019 Jun;162:199-206. doi: 10.1016/j.phytochem.2019.03.019. Epub 2019 Apr 1. Phytochemistry. 2019. PMID: 30947089

Twelve previously undescribed phenolic meroterpenoids, cochlearols N-Y, along with two known analogs, ganocochlearins B and C, were isolated from the fruiting bodies of Ganoderma cochlear. Most of these substances were isolated as racemic mixtures. The structures of cochle …

Twelve previously undescribed phenolic meroterpenoids, cochlearols N-Y, along with two known analogs, ganocochlearins B and C, were isolated …

75

Optimization of Ganoderma lucidum Polysaccharides Fermentation Process for Large-Scale Production.

Feng J, Feng N, Tang QJ, Liu YF, Yang Y, Liu F, Zhang JS, Lin CC. Feng J, et al. Appl Biochem Biotechnol. 2019 Nov;189(3):972-986. doi: 10.1007/s12010-019-02968-5. Epub 2019 Jun 3. Appl Biochem Biotechnol. 2019. PMID: 31161381

The objective of this study was to increase the intracellular polysaccharide yield of Ganoderma lucidum. The accordingly optimized fermentation medium by central composite design method contains glucose 40 g L(-1), yeast powder 12 g L(-1), potassium dihydrogen phosphate 3 …

The objective of this study was to increase the intracellular polysaccharide yield of Ganoderma lucidum. The accordingly optimized fe …

76

Ligninolytic enzymes from Ganoderma spp: current status and potential applications.

Zhou XW, Cong WR, Su KQ, Zhang YM. Zhou XW, et al. Crit Rev Microbiol. 2013 Nov;39(4):416-26. doi: 10.3109/1040841X.2012.722606. Epub 2012 Sep 20. Crit Rev Microbiol. 2013. PMID: 22992227 Review.

The current literature regarding lignin-modifying enzymes from the genus Ganoderma, their potential uses, and the components, structures and processes of lignocellulose degradation are discussed. ...This review will provide insight on the valuable applications of Ganode …

The current literature regarding lignin-modifying enzymes from the genus Ganoderma, their potential uses, and the components, structu …

77

Ganoderma boninense mycelia for phytochemicals and secondary metabolites with antibacterial activity.

Abdullah S, Jang SE, Kwak MK, Chong K. Abdullah S, et al. J Microbiol. 2020 Dec;58(12):1054-1064. doi: 10.1007/s12275-020-0208-z. Epub 2020 Dec 2. J Microbiol. 2020. PMID: 33263896

Antiplasmodial nortriterpenes with 3,4-seco-27-norlanostane skeletons, almost entirely obtained from fruiting bodies, represent the main evidential source for bioactive secondary metabolites derived from a relatively unexplored phytopathogenic fungus, Ganoderma boninense. …

Antiplasmodial nortriterpenes with 3,4-seco-27-norlanostane skeletons, almost entirely obtained from fruiting bodies, represent the main evi …

78

In vitro anti-Toxoplasma gondii activity of Ganoderma lucidum extracts.

Ahmadi M, Salimi M, Saraei M, Nezhad NS, Javadi A, Mohammadi F, Heydarian P, Ali E, Hajialilo E. Ahmadi M, et al. BMC Res Notes. 2023 May 18;16(1):82. doi: 10.1186/s13104-023-06355-6. BMC Res Notes. 2023. PMID: 37202827 Free PMC article.

OBJECTIVE: Ganoderma extracts have the potential to be used as anti-cancer, anti-inflammatory, immunomodulator, and antimicrobial agents, as evaluated in numerous studies. ...The highest percentage of mortality was related to hydroalcoholic extract. The EC50 of Ganoderm …

OBJECTIVE: Ganoderma extracts have the potential to be used as anti-cancer, anti-inflammatory, immunomodulator, and antimicrobial age …

79

Current Advances in the Antimicrobial Potential of Species of Genus Ganoderma (Higher Basidiomycetes) against Human Pathogenic Microorganisms (Review).

Rai MK, Gaikwad S, Nagaonkar D, dos Santos CA. Rai MK, et al. Int J Med Mushrooms. 2015;17(10):921-32. doi: 10.1615/intjmedmushrooms.v17.i10.20. Int J Med Mushrooms. 2015. PMID: 26756184 Review.

Ganoderma spp. are very important therapeutic mushrooms and have been used traditionally for 4000 years in the treatment of various human disorders. ...The main aim of this review is to discuss the possible use of Ganoderma extracts and their active principles in an …

Ganoderma spp. are very important therapeutic mushrooms and have been used traditionally for 4000 years in the treatment of various h …

80

Lanostane triterpenoids with anti-inflammatory activities from Ganoderma lucidum.

Su HG, Peng XR, Shi QQ, Huang YJ, Zhou L, Qiu MH. Su HG, et al. Phytochemistry. 2020 May;173:112256. doi: 10.1016/j.phytochem.2019.112256. Epub 2020 Feb 12. Phytochemistry. 2020. PMID: 32062196

Ganoderma lucidum is one of the most famous medicinal fungi and is traditional Chinese medicine with various biological activities in Asian countries. ...Ganoluciduone A was an unusual octonorlanostane, which was isolated from Ganoderma for the first time. In additi …

Ganoderma lucidum is one of the most famous medicinal fungi and is traditional Chinese medicine with various biological activities in …

81

Zizhines G-O, AchE inhibitory meroterpenoids from Ganoderma sinensis.

Luo Q, Cao WW, Wu ZH, Wang SM, Cheng YX. Luo Q, et al. Fitoterapia. 2019 Apr;134:411-416. doi: 10.1016/j.fitote.2019.03.016. Epub 2019 Mar 20. Fitoterapia. 2019. PMID: 30902752

Zizhines G-O (1-9), nine new meroterpenoids, and seven known analogs (10-16) were isolated from the dried fruiting bodies of Ganoderma sinensis. Their structures were identified by using spectroscopic data and CD curve comparison. ...

Zizhines G-O (1-9), nine new meroterpenoids, and seven known analogs (10-16) were isolated from the dried fruiting bodies of Ganoderma …

82

Lanostane triterpenoids from mycelia-associated Ganoderma sinense and their anti-inflammatory activity.

Teng L, Wang C, Cui B, Zhang J, Zhou S, Pan X, Pan F, Dai Y, Feng N. Teng L, et al. Phytochemistry. 2023 Nov;215:113870. doi: 10.1016/j.phytochem.2023.113870. Epub 2023 Sep 20. Phytochemistry. 2023. PMID: 37734511

Seven previously undescribed lanostane triterpenoids, ganoderic acid M1 (1), M2 (2), M3 (3), M4 (4), M5 (5), M6 (6), and M7 (7), together with eight known compounds, were isolated from mycelia of the basidiomycete Ganoderma sinense (Ganodermataceae). The structures of all …

Seven previously undescribed lanostane triterpenoids, ganoderic acid M1 (1), M2 (2), M3 (3), M4 (4), M5 (5), M6 (6), and M7 (7), together wi …

83

[Triterpenoids from Ganoderma theaecolum].

Liu LY, Kang J, Wu CH, Li Y, Chen RY. Liu LY, et al. Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(6):1075-1080. doi: 10.4268/cjcmm20160617. Zhongguo Zhong Yao Za Zhi. 2016. PMID: 28875673 Chinese.

Fifteenlanostane triterpenoids were isolated from the ethanol extract of Ganoderma theaecolum by means of preparative HPLC,column chromatography over silica gel,ODS and were identified as lucidone C(1),lucidone D(2),7-oxo-ganoderic acid Z2(3),7-oxo-ganoderic acid Z(4),gano …

Fifteenlanostane triterpenoids were isolated from the ethanol extract of Ganoderma theaecolum by means of preparative HPLC,column chr …

84

Novel Ganoderma triterpenoid saponins from the biotransformation-guided purification of a commercial Ganoderma extract.

Ding HY, Wang TY, Wu JY, Zhang YR, Chang TS. Ding HY, et al. J Biosci Bioeng. 2023 May;135(5):402-410. doi: 10.1016/j.jbiosc.2023.02.004. Epub 2023 Mar 6. J Biosci Bioeng. 2023. PMID: 36889998

Ganoderma sp. contains high amounts of diverse triterpenoids; however, few triterpenoid saponins could be isolated from the medicinal fungus. To produce novel Ganoderma triterpenoid saponins, biotransformation-guided purification (BGP) process was applied to a comme …

Ganoderma sp. contains high amounts of diverse triterpenoids; however, few triterpenoid saponins could be isolated from the medicinal …

85

Spiroganodermaines A-G from Ganoderma species and their activities against insulin resistance and renal fibrosis.

Zhang JJ, Wang DW, Peng YL, Cai D, Cheng YX. Zhang JJ, et al. Phytochemistry. 2022 Oct;202:113324. doi: 10.1016/j.phytochem.2022.113324. Epub 2022 Aug 2. Phytochemistry. 2022. PMID: 35931232

Ganoderma mushrooms are a renowned Chinese medicine and functional food used worldwide. Seven undescribed spiro Ganoderma meroterpenoids spiroganodermaines A-G were isolated from Ganoderma species. Their structures were characterized by using spectroscopic, c …

Ganoderma mushrooms are a renowned Chinese medicine and functional food used worldwide. Seven undescribed spiro Ganoderma mero …

86

De novo assembly and annotation of the Ganoderma australe genome.

Agudelo-Valencia D, Uribe-Echeverry PT, Betancur-Pérez JF. Agudelo-Valencia D, et al. Genomics. 2020 Jan;112(1):930-933. doi: 10.1016/j.ygeno.2019.06.008. Epub 2019 Jun 6. Genomics. 2020. PMID: 31175979 Free article.

The Ganoderma genus represents clear biotechnological potential, due to the large quantity of molecules with biological activity that could be explored. However, available information regarding the biotechnological importance of species within Ganoderma, other than …

The Ganoderma genus represents clear biotechnological potential, due to the large quantity of molecules with biological activity that …

87

Pharmacological and anti-tumor activities of ganoderma spores processed by top-down approaches.

Liu X, Wang JH, Yuan JP. Liu X, et al. J Nanosci Nanotechnol. 2005 Dec;5(12):2001-13. doi: 10.1166/jnn.2005.448. J Nanosci Nanotechnol. 2005. PMID: 16430134 Review.

However, the efficiency of Ganoderma in therapy has long been hindered by the uncertainty of its effectual constituents and the pharmaceutical mechanisms. ...The production of raw Ganoderma spores, the processing techniques to produce the sporoderm-broken germinatin …

However, the efficiency of Ganoderma in therapy has long been hindered by the uncertainty of its effectual constituents and the pharm …

88

GANODERMA LUCIDUM IMPROVES PHYSICAL FITNESS IN WOMEN WITH FIBROMYALGIA.

Collado Mateo D, Pazzi F, Domínguez Muñoz FJ, Martín Martínez JP, Olivares PR, Gusi N, Adsuar JC. Collado Mateo D, et al. Nutr Hosp. 2015 Nov 1;32(5):2126-35. doi: 10.3305/nh.2015.32.5.9601. Nutr Hosp. 2015. PMID: 26545669 Free article. Clinical Trial.

OBJECTIVE: to evaluate the effects of 6-week treatment of Ganoderma lucidum and Ceratonia siliqua on physical fitness in patients suffering from fibromyalgia. ...RESULTS: after the 6-week treatment period, Ganoderma lucidum significantly improved aerobic endurance, …

OBJECTIVE: to evaluate the effects of 6-week treatment of Ganoderma lucidum and Ceratonia siliqua on physical fitness in patients suf …

89

Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits.

Batra P, Sharma AK, Khajuria R. Batra P, et al. Int J Med Mushrooms. 2013;15(2):127-43. doi: 10.1615/intjmedmushr.v15.i2.20. Int J Med Mushrooms. 2013. PMID: 23557365 Review.

Ganoderma lucidum (Lingzhi or Reishi) is known as a bitter mushroom with remarkable health benefits. ...

90

Metabolic fingerprinting of Ganoderma spp. using UHPLC-ESI-QTOF-MS and its chemometric analysis.

Biswal RP, Dandamudi RB, Patnana DP, Pandey M, Vutukuri VNRK. Biswal RP, et al. Phytochemistry. 2022 Jul;199:113169. doi: 10.1016/j.phytochem.2022.113169. Epub 2022 Mar 22. Phytochemistry. 2022. PMID: 35331732

A UHPLC-QTOF-MS method was developed to separate and identify 70 triterpenes present in each of the 18 strains of Ganoderma spp. Collected from various parts of India. A PCDL MS library was used to retrieve and identify these 70 triterpenes by meticulous analysis of MS/MS …

A UHPLC-QTOF-MS method was developed to separate and identify 70 triterpenes present in each of the 18 strains of Ganoderma spp. Coll …

91

Phylogenetic analysis and morphological characteristics of laccate Ganoderma specimens in Finland.

Cortina-Escribano M, Veteli P, Wingfield MJ, Wingfield BD, Coetzee MPA, Vanhanen H, Linnakoski R. Cortina-Escribano M, et al. Mycologia. 2024 Nov-Dec;116(6):1046-1062. doi: 10.1080/00275514.2024.2381424. Epub 2024 Sep 12. Mycologia. 2024. PMID: 39264327 Free article.

The Ganoderma lucidum complex includes fungi with similar morphologies but which are thought to represent different species. ...But further investigation into the relationship between G. tsugae and G. lucidum from Europe will be needed to clarify the identity of the laccat …

The Ganoderma lucidum complex includes fungi with similar morphologies but which are thought to represent different species. ...But f …

92

Ganoderma adspersum, the Cause of Extensive Wood Decay of Almond Trees in California Orchards.

Ahumada DH, Johnson A', Cortez FES, Gordon PE, Culumber CM, Rizzo DM. Ahumada DH, et al. Plant Dis. 2025 Aug;109(8):1753-1759. doi: 10.1094/PDIS-03-24-0631-RE. Epub 2025 Aug 19. Plant Dis. 2025. PMID: 39970107

Ganoderma adspersum, previously unreported in North America, was identified as the primary causal agent of root and butt rot-related failure in almond trees in California's Central Valley. ...The most common sign is reddish-brown basidiomata that develop at the base of the …

Ganoderma adspersum, previously unreported in North America, was identified as the primary causal agent of root and butt rot-related …

93

Siderophores and secondary metabolites produced by Ganoderma adspersum.

Reyes C, Ahrendt S, Riley R, Lipzen A, Ng V, Grigoriev IV, Schwarze FWMR, Baars O. Reyes C, et al. Microbiology (Reading). 2025 Nov;171(11):001621. doi: 10.1099/mic.0.001621. Microbiology (Reading). 2025. PMID: 41237045 Free PMC article.

Ganoderma adspersum is a white-rot wood-degrading basidiomycete of ecological, biotechnological and medicinal interest. ...However, the mechanisms of iron acquisition, including siderophore-mediated pathways, remain poorly characterized in Ganoderma species. Improve …

Ganoderma adspersum is a white-rot wood-degrading basidiomycete of ecological, biotechnological and medicinal interest. ...However, t …

94

Optimization, purification and characterization of laccase from Ganoderma leucocontextum along with its phylogenetic relationship.

Umar A, Ahmed S. Umar A, et al. Sci Rep. 2022 Feb 14;12(1):2416. doi: 10.1038/s41598-022-06111-z. Sci Rep. 2022. PMID: 35165332 Free PMC article.

The aim of this work to study an efficient laccase producing fungus Ganoderma leucocontextum, which was identified by ITS regions of DNA and phylogenetic tree was constructed. ...

The aim of this work to study an efficient laccase producing fungus Ganoderma leucocontextum, which was identified by ITS regions of …

95

Isolation and Characterization of trans-p-Hydroxycinnamoyl Meroterpenoids from Ganoderma sinensis.

Yin YJ, Zhou H, Zhang JJ, Cai D, Yuan YN, Yang ZH, Cheng YX. Yin YJ, et al. Chem Biodivers. 2023 Apr;20(4):e202300022. doi: 10.1002/cbdv.202300022. Epub 2023 Mar 27. Chem Biodivers. 2023. PMID: 36971262

Zizhines V, W, Y, Z, ()-zizhines X, and Z1-Z3, and ()-ganosinensol L, thirteen new compounds including four pairs of enantiomers and a known compound (-)-ganosinensol L, were isolated from the fruiting bodies of Ganoderma sinensis. Their structures were identified by spect …

Zizhines V, W, Y, Z, ()-zizhines X, and Z1-Z3, and ()-ganosinensol L, thirteen new compounds including four pairs of enantiomers and a known …

96

Diverse meroterpenoids with alpha-glucosidase inhibitory activity from Ganoderma cochlear.

Fang DS, Cheng CR, Qiu MH, Peng XR. Fang DS, et al. Fitoterapia. 2023 Mar;165:105420. doi: 10.1016/j.fitote.2022.105420. Epub 2022 Dec 29. Fitoterapia. 2023. PMID: 36586625

Three new meroterpenoids, cochlearins J-L (1-3) and three known meroterpenoids (4-6) were isolated from the fruiting bodies of Ganoderma cochlear. NMR ((1)H and (13)C NMR, (1)H - (1)H COSY, HSQC, HMBC and ROESY), and HRESIMS were employed for the structure elucidation of n …

Three new meroterpenoids, cochlearins J-L (1-3) and three known meroterpenoids (4-6) were isolated from the fruiting bodies of Ganoderma …

97

[Molecular mechanism of Ganoderma against gastric cancer based on network pharmacology and experimental test].

Zhong JY, Chen HB, Ye DZ, Deng ZJ, Shao JJ, Han JW, Yuan JH, Deng NY. Zhong JY, et al. Zhongguo Zhong Yao Za Zhi. 2022 Jan;47(1):203-223. doi: 10.19540/j.cnki.cjcmm.20210902.701. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 35178927 Chinese.

This study aims to explore the molecular mechanism of Ganoderma against gastric cancer based on network pharmacology, molecular docking, and cell experiment. ...Molecular docking was performed between beta-sitosterol(the key component in Ganoderma) and the top 15 ta …

This study aims to explore the molecular mechanism of Ganoderma against gastric cancer based on network pharmacology, molecular docki …

98

Meroterpenoids containing benzopyran or benzofuran motif from Ganoderma cochlear.

Qin FY, Wang DW, Xu T, Zhang BS, Cheng YX. Qin FY, et al. Phytochemistry. 2022 Jul;199:113184. doi: 10.1016/j.phytochem.2022.113184. Epub 2022 Apr 9. Phytochemistry. 2022. PMID: 35405148

Five undescribed benzopyran containing meroterpenoids, ganodercins Q-U, two undescribed benzofuran containing meroterpenoids, ganodercins V and W, and two known meroterpenoids were isolated from Ganoderma cochlear. Their structures were elucidated by using HRESIMS, NMR spe …

Five undescribed benzopyran containing meroterpenoids, ganodercins Q-U, two undescribed benzofuran containing meroterpenoids, ganodercins V …

99

Whole-genome assembly of Ganoderma leucocontextum (Ganodermataceae, Fungi) discovered from the Tibetan Plateau of China.

Liu Y, Huang L, Hu H, Cai M, Liang X, Li X, Zhang Z, Xie Y, Xiao C, Chen S, Chen D, Yong T, Pan H, Gao X, Wu Q. Liu Y, et al. G3 (Bethesda). 2021 Dec 8;11(12):jkab337. doi: 10.1093/g3journal/jkab337. G3 (Bethesda). 2021. PMID: 34586388 Free PMC article.

Ganoderma leucocontextum, a newly discovered species of Ganodermataceae in China, has diverse pharmacological activities. Ganoderma leucocontextum was widely cultivated in southwest China, but the systematic genetic study has been impeded by the lack of a reference …

Ganoderma leucocontextum, a newly discovered species of Ganodermataceae in China, has diverse pharmacological activities. Ganoderm …

100

Taxonomy and species diversity of Ganoderma species in the Garden Route National Park of South Africa inferred from morphology and multilocus phylogenies.

Tchotet Tchoumi JM, Coetzee MPA, Rajchenberg M, Roux J. Tchotet Tchoumi JM, et al. Mycologia. 2019 Sep-Oct;111(5):730-747. doi: 10.1080/00275514.2019.1635387. Epub 2019 Aug 26. Mycologia. 2019. PMID: 31449474

Identification was achieved by means of multilocus phylogenetic inference combined with morphological evaluation. In total, eight distinct species of Ganoderma were recovered from different hosts and localities across the country. Of these, Ganoderma cf. cupreum and …

Identification was achieved by means of multilocus phylogenetic inference combined with morphological evaluation. In total, eight distinct s …

101

The effect of Ganoderma lucidum polysaccharide extract on sensitizing prostate cancer cells to flutamide and docetaxel: an in vitro study.

Rahimnia R, Akbari MR, Yasseri AF, Taheri D, Mirzaei A, Ghajar HA, Farashah PD, Baghdadabad LZ, Aghamir SMK. Rahimnia R, et al. Sci Rep. 2023 Nov 2;13(1):18940. doi: 10.1038/s41598-023-46118-8. Sci Rep. 2023. Retraction in: Sci Rep. 2026 Jan 6;16(1):427. doi: 10.1038/s41598-025-34603-1. PMID: 37919464 Free PMC article. Retracted.

Ganoderma lucidum polysaccharide is the most widely used complementary therapy in cancer. ...Ganoderma lucidum polysaccharide synergistically increased the effect of Docetaxel and Flutamide and increased the sensitivity of the prostate cancer cell lines to these dru …

Ganoderma lucidum polysaccharide is the most widely used complementary therapy in cancer. ...Ganoderma lucidum polysaccharide …

102

Australeols A-F, neuroprotective meroterpenoids from Ganoderma australe.

Zhang JJ, Dong Y, Qin FY, Cheng YX. Zhang JJ, et al. Fitoterapia. 2019 Apr;134:250-255. doi: 10.1016/j.fitote.2019.02.021. Epub 2019 Feb 28. Fitoterapia. 2019. PMID: 30825574

Six new meroterpenoids, australeols A-F (1-6), together with nineteen known compounds (7-25), were isolated from the fruiting bodies of Ganoderma australe. Their structures including absolute configurations were assigned by using spectroscopic methods, CD comparison, and X …

Six new meroterpenoids, australeols A-F (1-6), together with nineteen known compounds (7-25), were isolated from the fruiting bodies of G …

103

[Research progress on chemical constituents and pharmacological effects of Ganoderma lucidum spore oil].

Kang XH, Li P. Kang XH, et al. Zhongguo Zhong Yao Za Zhi. 2025 Apr;50(8):2071-2079. doi: 10.19540/j.cnki.cjcmm.20250131.203. Zhongguo Zhong Yao Za Zhi. 2025. PMID: 40461239 Review. Chinese.

Originating from sporoderm-broken Ganoderma lucidum spores, Ganoderma lucidum spore oil(GLSO) is prepared by supercritical fluid extraction. ...

Originating from sporoderm-broken Ganoderma lucidum spores, Ganoderma lucidum spore oil(GLSO) is prepared by supercritical flu …

104

Interspecific hybridization between Ganoderma lingzhi and G. applanatum through protoplast fusion.

Raman J, Jang KY, Oh YL, Oh M, Im JH, Lakshmanan H, Kong WS. Raman J, et al. World J Microbiol Biotechnol. 2021 Jun 11;37(7):114. doi: 10.1007/s11274-021-03084-5. World J Microbiol Biotechnol. 2021. PMID: 34115218

Interspecific hybridization between Ganoderma lingzhi and G. applanatum was attempted through polyethylene glycol (PEG) induced fusion technique. The protoplast isolation procedure was simplified, and we obtained a significant number of protoplasts from both Ganoderma …

Interspecific hybridization between Ganoderma lingzhi and G. applanatum was attempted through polyethylene glycol (PEG) induced fusio …

105

[The pharmacological study of Ganoderma spores and their active components].

Lin ZB, Wang PY. Lin ZB, et al. Beijing Da Xue Xue Bao Yi Xue Ban. 2006 Oct 18;38(5):541-7. Beijing Da Xue Xue Bao Yi Xue Ban. 2006. PMID: 17068632 Free article. Review. Chinese.

Recently, the pharmacological study of Ganoderma spores and active components has become a focus of attention in the world. The present review is based on the auctorial research on Ganoderma spores. It involves pharmacological effects of Ganoderma spores and …

Recently, the pharmacological study of Ganoderma spores and active components has become a focus of attention in the world. The prese …

106

Antimicrobial lanostane triterpenoids from the fruiting bodies of Ganoderma applanatum.

Shi JX, Chen GY, Sun Q, Meng SY, Chi WQ. Shi JX, et al. J Asian Nat Prod Res. 2022 Nov;24(11):1001-1007. doi: 10.1080/10286020.2021.2017899. Epub 2021 Dec 20. J Asian Nat Prod Res. 2022. PMID: 34923886

A chemical investigation on the 90% EtOH extract of the fruiting bodies of Ganoderma applanatum led to the isolation of three new lanostane triterpenoids, designated as 25-methoxy-11-oxo-ganoderiol D (1), 3-oxo-25-methoxy-24,26-dihydroxy-lanosta-7,9(11)-diene (2), and 3bet …

A chemical investigation on the 90% EtOH extract of the fruiting bodies of Ganoderma applanatum led to the isolation of three new lan …

107

Triterpenoids from the fruiting bodies of Ganoderma lucidum and their inhibitory activity against FAAH.

Lin YX, Sun JT, Liao ZZ, Sun Y, Tian XG, Jin LL, Wang C, Leng AJ, Zhou J, Li DW. Lin YX, et al. Fitoterapia. 2022 Apr;158:105161. doi: 10.1016/j.fitote.2022.105161. Epub 2022 Feb 22. Fitoterapia. 2022. PMID: 35217118

Seventeen triterpenoids including four new lanostane triterpenoids (1-3 and 5) were isolated from the fruiting bodies of Ganoderma lucidum by various chromatographic techniques. Their chemical structures were determined by extensive spectroscopic data, including 1D-NMR, 2D …

Seventeen triterpenoids including four new lanostane triterpenoids (1-3 and 5) were isolated from the fruiting bodies of Ganoderma lu …

108

Intraspecific Identification of Lingzhi Medicinal Mushroom, Ganoderma lingzhi (Agaricomycetes), Using ISSR Markers.

He L, Yao K, Xu X, Li F, Luo X. He L, et al. Int J Med Mushrooms. 2022;24(4):43-52. doi: 10.1615/IntJMedMushrooms.2022043141. Int J Med Mushrooms. 2022. PMID: 35695595

This study aimed to obtain a set of specific inter simple sequence repeat (ISSR) primers and establish a stable and accurate intraspecific identification method for Ganoderma lingzhi. A total of 117 G. lingzhi strains were identified using internal transcribed spacer seque …

This study aimed to obtain a set of specific inter simple sequence repeat (ISSR) primers and establish a stable and accurate intraspecific i …

109

The bHLH-zip transcription factor SREBP regulates triterpenoid and lipid metabolisms in the medicinal fungus Ganoderma lingzhi.

Liu YN, Wu FY, Tian RY, Shi YX, Xu ZQ, Liu JY, Huang J, Xue FF, Liu BY, Liu GQ. Liu YN, et al. Commun Biol. 2023 Jan 3;6(1):1. doi: 10.1038/s42003-022-04154-6. Commun Biol. 2023. PMID: 36596887 Free PMC article.

Ganoderic acids (GAs) are well recognized as important pharmacological components of the medicinal species belonging to the basidiomycete genus Ganoderma. However, transcription factors directly regulating the expression of GA biosynthesis genes remain poorly understood. H …

Ganoderic acids (GAs) are well recognized as important pharmacological components of the medicinal species belonging to the basidiomycete ge …

110

An insight into spore dispersal of Ganoderma boninense on oil palm.

Sanderson FR. Sanderson FR. Mycopathologia. 2005 Jan;159(1):139-41. doi: 10.1007/s11046-004-4436-2. Mycopathologia. 2005. PMID: 15750746 Review.

The disease of oil palm caused by Ganoderma boninense, although universally referred to as Ganoderma basal stem rot, occurs in three very distinct phases, with basal stem rot only part of the disease cycle. ...

The disease of oil palm caused by Ganoderma boninense, although universally referred to as Ganoderma basal stem rot, occurs in …

111

The Domestication and Cultivation of Ganoderma (Agaricomycetes) Medicinal Mushroom Species from Nigeria.

Ofodile LN, Isikhuemhen OS, Anike FN, Adekunle AA. Ofodile LN, et al. Int J Med Mushrooms. 2022;24(6):69-78. doi: 10.1615/IntJMedMushrooms.2022043906. Int J Med Mushrooms. 2022. PMID: 35695639

Commercial cultivation of Ganoderma species found in Nigeria does not exist. Four Ganoderma isolates (YCT-BKS, YCT-Q2, YCT-Q14, and YCT-Q18) collected in Lagos were tested for mycelia growth and cultivation in sawdust-based substrates. ...Results indicate the need t …

Commercial cultivation of Ganoderma species found in Nigeria does not exist. Four Ganoderma isolates (YCT-BKS, YCT-Q2, YCT-Q14 …

112

Ganoderma australe from southern India.

Kaliyaperumal M, Kalaichelvan PT. Kaliyaperumal M, et al. Microbiol Res. 2008;163(3):286-92. doi: 10.1016/j.micres.2007.01.003. Epub 2007 Apr 25. Microbiol Res. 2008. PMID: 17462872 Free article.

The genetic diversity of Ganoderma australe (Fr.) Pat. from southern India was investigated by using ITS1/2 rDNA. ...

113

Lanostane triterpenoids from the fruiting bodies of Ganoderma amboinense.

Yang L, Dong GH, Ma QY, Xie QY, Guo JC, Lu JJ, Wu YG, Dai HF, Zhao YX. Yang L, et al. Phytochemistry. 2024 Feb;218:113952. doi: 10.1016/j.phytochem.2023.113952. Epub 2023 Dec 12. Phytochemistry. 2024. PMID: 38096963

Lanostane-type triterpenoids are the main characteristic constituents in Ganoderma mushrooms. Phytochemical analysis on the ethanol extract of the fruiting bodies of Ganoderma amboinense led to isolation and identification of twelve previously undescribed lanostane …

Lanostane-type triterpenoids are the main characteristic constituents in Ganoderma mushrooms. Phytochemical analysis on the ethanol e …

114

Drimane sesquiterpenoids from cultures of basidiomycete Ganoderma subresinosum.

Yangchum A, Sappan M, Choowong W, Thummarukcharoen T, Boonpratuang T, Isaka M, Seephonkai P. Yangchum A, et al. J Nat Med. 2025 Sep;79(5):1081-1090. doi: 10.1007/s11418-025-01931-5. Epub 2025 Jul 7. J Nat Med. 2025. PMID: 40622675

Nine previously undescribed drimane sesquiterpenoids, ganoresinosins A-I (1-9), were isolated from cultures of basidiomycete Ganoderma subresinosum. The absolute configuration of ganoresinosin H (8) was determined using the modified Mosher's method. ...

Nine previously undescribed drimane sesquiterpenoids, ganoresinosins A-I (1-9), were isolated from cultures of basidiomycete Ganoderma …

115

Ganoderma lucidum mycelia enhance innate immunity by activating NF-kappaB.

Kuo MC, Weng CY, Ha CL, Wu MJ. Kuo MC, et al. J Ethnopharmacol. 2006 Jan 16;103(2):217-22. doi: 10.1016/j.jep.2005.08.010. Epub 2005 Sep 15. J Ethnopharmacol. 2006. PMID: 16169168

Ganoderma lucidum is a popular medicinal mushroom in China and Japan for its immunomodulatory and antitumor effects. ...IFN-gamma release from human whole blood was also enhanced after 3 day-culture with Ganoderma lucidum mycelia (0.2-1.0mg/ml). However, Ganoderm …

Ganoderma lucidum is a popular medicinal mushroom in China and Japan for its immunomodulatory and antitumor effects. ...IFN-gamma rel …

116

Multilocus, Multiplex Detection of Ganoderma zonatum from Environmental Samples.

Chakrabarti S, Loyd AL, Dhillon B. Chakrabarti S, et al. Plant Dis. 2023 Mar;107(3):682-687. doi: 10.1094/PDIS-12-21-2837-RE. Epub 2023 Mar 3. Plant Dis. 2023. PMID: 35869585

Ganoderma butt rot of palms is caused by a white rot basidiomycete fungus, Ganoderma zonatum. ...Primers tailored to end on single-nucleotide polymorphisms (SNPs), that differentiate G. zonatum from 14 other Ganoderma taxa, were designed from multiple regions …

Ganoderma butt rot of palms is caused by a white rot basidiomycete fungus, Ganoderma zonatum. ...Primers tailored to end on si …

117

Investigating the therapeutic potential of Ganoderma lucidum in treating optic nerve atrophy through network pharmacology and experimental validation.

Zhilin L, Haobo F, Juan W, AiRui X, XiaoDong L, Yuan Y, Junguo D. Zhilin L, et al. Biochem Biophys Res Commun. 2025 May 26;760:151702. doi: 10.1016/j.bbrc.2025.151702. Epub 2025 Mar 26. Biochem Biophys Res Commun. 2025. PMID: 40158404

In the first part, the chemical composition and Target of Ganoderma lucidum compound were predicted by TCMSP and Swiss Target Prediction, and the crossover gene between OA and Ganoderma lucidum target gene was screened based on GeneCards and OMIM database. ...These …

In the first part, the chemical composition and Target of Ganoderma lucidum compound were predicted by TCMSP and Swiss Target Predict …

118

Time-dependent change in Reishi (Ganoderma lingzhi) triterpenoids in culture with rumen fluid.

Baba A, Ichikawa N, Yamanaka M, Wang D, Isa A, Hirayama T, Shimizu K, Nakagawa T. Baba A, et al. Anim Sci J. 2024 Jan-Dec;95(1):e13957. doi: 10.1111/asj.13957. Anim Sci J. 2024. PMID: 38783587

The purpose of this study was to investigate the time-dependent change in Reishi (Ganoderma lingzhi) triterpenoids in rumen fluid. G. lingzhi fruiting bodies were milled and incubated in a tube with rumen fluid for 0, 4, 8, 12, 24, and 48 h at 39C. ...

The purpose of this study was to investigate the time-dependent change in Reishi (Ganoderma lingzhi) triterpenoids in rumen fluid. G. …

119

Identification a novel Ganoderma FIP gene from Ganoderma capense and its functional expression in Pichia pastoris.

Lin J, Liao Y, Yang S, Jin T, Yu B, Zhao K, Sai Y, Lin C, Song Y, Ma H, Wang Z. Lin J, et al. World J Microbiol Biotechnol. 2024 Jan 16;40(2):69. doi: 10.1007/s11274-023-03869-w. World J Microbiol Biotechnol. 2024. PMID: 38225505

Ganoderma capense is a precious medicinal fungus in China. In this study, a novel fungal immunomodulatory protein gene, named as FIP-gca, was cloned from G. capense by homologous cloning. ...Protein sequence blasting and phylogenetic analysis showed that FIP-gca shared hom …

Ganoderma capense is a precious medicinal fungus in China. In this study, a novel fungal immunomodulatory protein gene, named as FIP- …

120

Phylogenetic analysis and morphology of Ganoderma multipileum, a Ganoderma species associated with dieback of the metropolitan woody plant Delonix regia (Boj. ex Hook.) Raf. in Vietnam.

Nguyen TTT, Nguyen HD, Bui AT, Pham KHT, Van KTP, Tran LT, Tran MH. Nguyen TTT, et al. Sci Prog. 2023 Jul-Sep;106(3):368504231195503. doi: 10.1177/00368504231195503. Sci Prog. 2023. PMID: 37611190 Free PMC article.

Ganoderma multipileum, a wood decay mushroom, was initially discovered and classified in Taiwan through the analysis of its morphology and the internal transcribed spacer (ITS) region of nuclear ribosomal DNA. ...Notably, scanning electron microscopy of the basidiospores r …

Ganoderma multipileum, a wood decay mushroom, was initially discovered and classified in Taiwan through the analysis of its morpholog …

121

Nor-triterpenoids from the fruiting bodies of Ganoderma lucidum and their inhibitory activity against FAAH.

Li D, Leng Y, Liao Z, Hu J, Sun Y, Deng S, Wang C, Tian X, Zhou J, Wang R. Li D, et al. Nat Prod Res. 2023 Feb;37(4):579-585. doi: 10.1080/14786419.2022.2078817. Epub 2022 May 24. Nat Prod Res. 2023. PMID: 35608196

Two new nor-triterpenoids ganodrenol A (1), B (2), and a new natural product ganodrenol C (3), along with three known nor-triterpenoids (4-6) were isolated from the fruiting bodies of Ganoderma lucidum. The chemical structures of these isolates were determined by 1 D and 2 …

Two new nor-triterpenoids ganodrenol A (1), B (2), and a new natural product ganodrenol C (3), along with three known nor-triterpenoids (4-6 …

122

Overexpression of phosphomannomutase increases the production and bioactivities of Ganoderma exopolysaccharides.

Zhao LN, Cao YB, Luo Q, Xu YL, Li N, Wang CX, Xu JW. Zhao LN, et al. Carbohydr Polym. 2022 Oct 15;294:119828. doi: 10.1016/j.carbpol.2022.119828. Epub 2022 Jul 5. Carbohydr Polym. 2022. PMID: 35868775

In this study, we explored a novel approach to enhancing the production and bioactivities of Ganoderma exopolysaccharides. The homologous phosphomannomutase gene (PMM1) was cloned and overexpressed in Ganoderma for the first time. ...In conclusion, this study is hel …

In this study, we explored a novel approach to enhancing the production and bioactivities of Ganoderma exopolysaccharides. The homolo …

123

Lanostane triterpenoids with anti-proliferative and anti-inflammatory activities from medicinal mushroom Ganoderma lingzhi.

Zhao ZZ, Ji BY, Wang ZZ, Si YY, Sun YJ, Chen H, Feng WS, Zheng XK, Liu JK. Zhao ZZ, et al. Phytochemistry. 2023 Sep;213:113791. doi: 10.1016/j.phytochem.2023.113791. Epub 2023 Jul 14. Phytochemistry. 2023. PMID: 37454886

Eight previously undescribed lanostane triterpenoids and nine known ones were identified from the fruiting bodies of Ganoderma lingzhi S.H. Wu, Y. Cao & Y.C. Dai. Their structures were determined based on spectroscopic data and quantum chemical calculations. ...

Eight previously undescribed lanostane triterpenoids and nine known ones were identified from the fruiting bodies of Ganoderma lingzh …

124

On the Typification of Ganoderma sichuanense (Agaricomycetes)-the Widely Cultivated Lingzhi Medicinal Mushroom.

Yao YJ, Li Y, Du Z, Wang K, Wang XC, Kirk PM, Spooner BM. Yao YJ, et al. Int J Med Mushrooms. 2020;22(1):45-54. doi: 10.1615/IntJMedMushrooms.2019033189. Int J Med Mushrooms. 2020. PMID: 32463997

The well-known and widely cultivated lingzhi has had a significant impact on Chinese culture and is now an important fungal crop providing medicinal benefits to human health and economic value to social development within China and around the world. The European mushroom name, …

The well-known and widely cultivated lingzhi has had a significant impact on Chinese culture and is now an important fungal crop providing m …

125

Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents.

Su HG, Wang Q, Zhou L, Peng XR, Xiong WY, Qiu MH. Su HG, et al. Bioorg Chem. 2021 Jul;112:104977. doi: 10.1016/j.bioorg.2021.104977. Epub 2021 May 7. Bioorg Chem. 2021. PMID: 34020237

Previously, we have demonstrated the antiadipogenic benefits of Ganoderma triterpenoids (GTs), which indicated GTs have potential therapeutic implications for obesity. In this study, the EtOAc extract of Ganoderma applanatum was further phytochemically investigated …

Previously, we have demonstrated the antiadipogenic benefits of Ganoderma triterpenoids (GTs), which indicated GTs have potential the …

126

Autotoxicity of Endogenous Organic Acid Stress in Two Ganoderma lucidum Cultivars.

Zou P, Guo Y, Ding S, Song Z, Cui H, Zhang Y, Zhang Z, Chen X. Zou P, et al. Molecules. 2022 Oct 9;27(19):6734. doi: 10.3390/molecules27196734. Molecules. 2022. PMID: 36235268 Free PMC article.

Ganoderma lucidum has been used as a rare medical mushroom for centuries in China, due to its health-promoting properties. ...

127

Antitubercular Activity of Mycelium-Associated Ganoderma Lanostanoids.

Isaka M, Chinthanom P, Sappan M, Supothina S, Vichai V, Danwisetkanjana K, Boonpratuang T, Hyde KD, Choeyklin R. Isaka M, et al. J Nat Prod. 2017 May 26;80(5):1361-1369. doi: 10.1021/acs.jnatprod.6b00973. Epub 2017 May 15. J Nat Prod. 2017. PMID: 28504879

In a continuation of our research into antitubercular lanostane triterpenoids from submerged cultures of Ganoderma species, three strains, Ganoderma orbiforme BCC 22325, Ganoderma sp. BCC 60695, and Ganoderma australe BCC 22314, have been investigated. …

In a continuation of our research into antitubercular lanostane triterpenoids from submerged cultures of Ganoderma species, three str …

128

Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay.

Zhou H, Peng X, Hou T, Zhao N, Qiu M, Zhang X, Liang X. Zhou H, et al. J Ethnopharmacol. 2020 Jan 10;246:112218. doi: 10.1016/j.jep.2019.112218. Epub 2019 Sep 5. J Ethnopharmacol. 2020. PMID: 31494202

The current research studied five fungi from the genus Ganoderma and five plants: Ganoderma hainanense J.D. Zhao, L.W. Hsu & X.Q. Zhang; Ganoderma capense (Lloyd) Teng, Zhong Guo De Zhen Jun; Ganoderma cochlear (Blume & T. Nees) Bres., Hedwigia …

The current research studied five fungi from the genus Ganoderma and five plants: Ganoderma hainanense J.D. Zhao, L.W. Hsu &am …

129

Renoprotective ganodermaones A and B with rearranged meroterpenoid carbon skelotons from Ganoderma fungi.

Zhang JJ, Qin FY, Meng XH, Yan YM, Cheng YX. Zhang JJ, et al. Bioorg Chem. 2020 Jul;100:103930. doi: 10.1016/j.bioorg.2020.103930. Epub 2020 May 14. Bioorg Chem. 2020. PMID: 32450386

Two structurally novel meroterpenoids, ganodermaones A (1) and B (2), were isolated from Ganoderma fungi (G. cochlear and G. lucidum). The structures of 1 and 2 were assigned by spectroscopic, computational, and X-ray diffraction methods. Compounds 1 and 2 represent the fi …

Two structurally novel meroterpenoids, ganodermaones A (1) and B (2), were isolated from Ganoderma fungi (G. cochlear and G. lucidum) …

130

Antimicrobial Activities of Ganoderma mbrekobenum Strain EGDA (Agaricomycetes) from Egypt.

El-Dein MMN, El-Fallal AA, El-Sayed AKA, El-Esseily SR. El-Dein MMN, et al. Int J Med Mushrooms. 2023;25(9):31-41. doi: 10.1615/IntJMedMushrooms.2023049502. Int J Med Mushrooms. 2023. PMID: 37824404

Ganoderma is a well-known genus of medicinal mushrooms. The biological activity of the fruiting bodies of G. mbrekobenum (previously identified as Ganoderma sp. ...

Ganoderma is a well-known genus of medicinal mushrooms. The biological activity of the fruiting bodies of G. mbrekobenum (previously …

131

Bioprospecting of the agaricomycete Ganoderma australe GPC191 as novel source for L-asparaginase production.

Chakraborty M, Shivakumar S. Chakraborty M, et al. Sci Rep. 2021 Mar 18;11(1):6192. doi: 10.1038/s41598-021-84949-5. Sci Rep. 2021. PMID: 33737513 Free PMC article.

The isolate displaying the desired enzyme production was subjected to morphological, molecular identification, and phylogenetic analysis with statistical validation using Jukes-Cantor by Neighbour-joining tree of Maximum Likelihood statistical method. Among the isolates, Ganod …

The isolate displaying the desired enzyme production was subjected to morphological, molecular identification, and phylogenetic analysis wit …

132

The complete mitochondrial genomes of five important medicinal Ganoderma species: Features, evolution, and phylogeny.

Li Q, Xiang D, Wan Y, Wu Q, Wu X, Ma C, Song Y, Zhao G, Huang W. Li Q, et al. Int J Biol Macromol. 2019 Oct 15;139:397-408. doi: 10.1016/j.ijbiomac.2019.08.003. Epub 2019 Aug 2. Int J Biol Macromol. 2019. PMID: 31381907

In order to assess variation and conservation among Ganoderma species and reconstruct the phylogeny of the Ganoderma lucidum complex, complete mitogenomes of five Ganoderma species were sequenced and successfully assembled. The five Ganoderma mitogenom …

In order to assess variation and conservation among Ganoderma species and reconstruct the phylogeny of the Ganoderma lucidum c …

133

Comparative proteomic analysis of two divergent strains provides insights into thermotolerance mechanisms of Ganoderma lingzhi.

Cai M, Wu X, Liang X, Hu H, Liu Y, Yong T, Li X, Xiao C, Gao X, Chen S, Xie Y, Wu Q. Cai M, et al. Fungal Genet Biol. 2023 Jun;167:103796. doi: 10.1016/j.fgb.2023.103796. Epub 2023 May 4. Fungal Genet Biol. 2023. PMID: 37146899

However, the genetic basis of thermotolerance in Ganoderma lingzhi (G. lingzhi) remains largely unknown. In this study, we investigated the thermotolerance capacities of 21 G. lingzhi strains and screened the thermo-tolerant (S566) and heat-sensitive (Z381) strains. ...

However, the genetic basis of thermotolerance in Ganoderma lingzhi (G. lingzhi) remains largely unknown. In this study, we investigat …

134

Aromatic constituents from Ganoderma lucidum and their neuroprotective and anti-inflammatory activities.

Lu SY, Peng XR, Dong JR, Yan H, Kong QH, Shi QQ, Li DS, Zhou L, Li ZR, Qiu MH. Lu SY, et al. Fitoterapia. 2019 Apr;134:58-64. doi: 10.1016/j.fitote.2019.01.013. Epub 2019 Feb 11. Fitoterapia. 2019. PMID: 30763720

Five new aromatic compounds, designed as lucidumins A-D (1-4) and lucidimine E (9), along with seven known aromatic compounds (5-8, 10-12) were isolated from Ganoderma lucidum. Their structures were determined by spectroscopic method. Bioactive evaluation showed that compo …

Five new aromatic compounds, designed as lucidumins A-D (1-4) and lucidimine E (9), along with seven known aromatic compounds (5-8, 10-12) w …

135

Lanostane triterpenoids from the fruiting bodies of Ganoderma hainanense and their cytotoxic activity.

Xu Q, Sheng CY. Xu Q, et al. J Asian Nat Prod Res. 2023 Apr;25(4):342-348. doi: 10.1080/10286020.2022.2094787. Epub 2022 Jun 30. J Asian Nat Prod Res. 2023. PMID: 35771834

Three undescribed lanostane triterpenoids, 24E-en-11-oxo-ganoderiol D (1), 11beta-hydroxy-ganoderiol D (2), and 11beta-hydroxy-lucidone H (3) were isolated from the 80% EtOH extract of the fruiting bodies of Ganoderma hainanense. Structural elucidation of all the compounds …

Three undescribed lanostane triterpenoids, 24E-en-11-oxo-ganoderiol D (1), 11beta-hydroxy-ganoderiol D (2), and 11beta-hydroxy-lucidone H (3 …

136

What Is Ganoderma lucidum in the Molecular Era?

Papp V, Dima B, Wasser SP. Papp V, et al. Int J Med Mushrooms. 2017;19(7):575-593. doi: 10.1615/IntJMedMushrooms.2017021195. Int J Med Mushrooms. 2017. PMID: 29199580

The scientific name Ganoderma lucidum has long been used in the global medicinal mushroom market, and many publications have proven its pharmacological properties and chemical components. Although several Ganoderma species have been described worldwide as having mor …

The scientific name Ganoderma lucidum has long been used in the global medicinal mushroom market, and many publications have proven i …

137

Protective effects of Ganoderma triterpenoids on cadmium-induced oxidative stress and inflammatory injury in chicken livers.

Li T, Yu H, Song Y, Zhang R, Ge M. Li T, et al. J Trace Elem Med Biol. 2019 Mar;52:118-125. doi: 10.1016/j.jtemb.2018.12.010. Epub 2018 Dec 15. J Trace Elem Med Biol. 2019. PMID: 30732871

Several studies have been conducted on liver damage caused by cadmium, but few on the protective effects of Ganoderma triterpenoids against liver damage due to cadmium. This experiment was designed to evaluate the protective effects of Ganoderma triterpenoids on the …

Several studies have been conducted on liver damage caused by cadmium, but few on the protective effects of Ganoderma triterpenoids a …

138

Exploration of the anti-insomnia mechanism of Ganoderma by central-peripheral multi-level interaction network analysis.

Qiu Y, Mao ZJ, Ruan YP, Zhang X. Qiu Y, et al. BMC Microbiol. 2021 Oct 29;21(1):296. doi: 10.1186/s12866-021-02361-5. BMC Microbiol. 2021. PMID: 34715778 Free PMC article.

However, the mechanism by which Ganoderma ameliorates insomnia is unclear. We explored the mechanism of the anti-insomnia effect of Ganoderma using systems pharmacology from the perspective of central-peripheral multi-level interaction network analysis. ...Therefore …

However, the mechanism by which Ganoderma ameliorates insomnia is unclear. We explored the mechanism of the anti-insomnia effect of …

139

Inhibitory Effect of Five Ganoderma Species (Agaricomycetes) against Key Digestive Enzymes Related to Type 2 Diabetes Mellitus.

Chen SD, Yong TQ, Zhang YF, Hu HP, Xie YZ. Chen SD, et al. Int J Med Mushrooms. 2019;21(7):703-711. doi: 10.1615/IntJMedMushrooms.v21.i7.70. Int J Med Mushrooms. 2019. PMID: 31679304

Ganoderma mushrooms are widely used in clinical therapies and functional foods. The antidiabetic effect of Ganoderma has become a research hot spot in recent decades. To search for a superior antidiabetic Ganoderma extract, five common Ganoderma specie …

Ganoderma mushrooms are widely used in clinical therapies and functional foods. The antidiabetic effect of Ganoderma has becom …

140

Biophysical characterization of antibacterial compounds derived from pathogenic fungi Ganoderma boninense.

Abdullah S, Oh YS, Kwak MK, Chong K. Abdullah S, et al. J Microbiol. 2021 Feb;59(2):164-174. doi: 10.1007/s12275-021-0551-8. Epub 2020 Dec 23. J Microbiol. 2021. PMID: 33355891 Free PMC article.

There have been relatively few studies which support a link between Ganoderma boninense, a phytopathogenic fungus that is particularly cytotoxic and pathogenic to plant tissues and roots, and antimicrobial compounds. ...

There have been relatively few studies which support a link between Ganoderma boninense, a phytopathogenic fungus that is particularl …

141

Lanostane triterpenoids from artificially cultivated fruiting bodies of Ganoderma cf. mastoporum.

Yangchum A, Rachtawee P, Srichomthong K, Choeyklin R, Boonpratuang T, Thongpanchang C, Isaka M. Yangchum A, et al. Nat Prod Res. 2024 Aug;38(15):2644-2652. doi: 10.1080/14786419.2023.2196723. Epub 2023 Apr 11. Nat Prod Res. 2024. PMID: 37039449

In the quest for bioactive compounds from Ganoderma, artificially cultivated fruiting bodies of Ganoderma cf. mastoporum, strain TBRC-BCC 47851 were chemically investigated. ...

In the quest for bioactive compounds from Ganoderma, artificially cultivated fruiting bodies of Ganoderma cf. mastoporum, stra …

142

Antioxidant farnesylated hydroquinones from Ganoderma capense.

Peng X, Li L, Wang X, Zhu G, Li Z, Qiu M. Peng X, et al. Fitoterapia. 2016 Jun;111:18-23. doi: 10.1016/j.fitote.2016.04.006. Epub 2016 Apr 13. Fitoterapia. 2016. PMID: 27083379

Phytochemical investigation of the fruiting bodies of Ganoderma capense led to isolation of eight aromatic meroterpenoids (1-8). Ganocapensins A and B (1, 2) possessed a thirteen-membered and a fourteen-membered ether rings, respectively. ...

Phytochemical investigation of the fruiting bodies of Ganoderma capense led to isolation of eight aromatic meroterpenoids (1-8). Gano …

143

Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum.

Peng X, Li L, Dong J, Lu S, Lu J, Li X, Zhou L, Qiu M. Peng X, et al. Phytochemistry. 2019 Jan;157:103-110. doi: 10.1016/j.phytochem.2018.10.011. Epub 2018 Nov 1. Phytochemistry. 2019. PMID: 30390604

Twelve previously undescribed lanostane-type triterpenoids, including three triterpenoids with a gamma-lactone ring, namely applanlactones A-C, four highly oxygenated lanostane triterpenoids, namely methyl applaniate A and applanoic acids B-D, as well as five C21 nortriterpenoids …

Twelve previously undescribed lanostane-type triterpenoids, including three triterpenoids with a gamma-lactone ring, namely applanlactones A …

144

Intraspecific comparison of mitochondrial genomes reveals the evolution in medicinal fungus Ganoderma lingzhi.

Meng G, Ye L, Ma S, Wu L, Deng Y, Wu X. Meng G, et al. J Biosci Bioeng. 2022 Nov;134(5):374-383. doi: 10.1016/j.jbiosc.2022.07.003. Epub 2022 Sep 6. J Biosci Bioeng. 2022. PMID: 36075811

Several mitogenomes of the genus Ganoderma have been assembled, but intraspecific comparisons of mitogenomes in Ganoderma lingzhi have not been reported. ...

Several mitogenomes of the genus Ganoderma have been assembled, but intraspecific comparisons of mitogenomes in Ganoderma ling …

145

Systems Pharmacology-based Drug Discovery and Active Mechanism of Ganoderma lucidum Triterpenoids for Type 2 Diabetes Mellitus by Integrating Network Pharmacology and Molecular Docking.

Shi J, Chen J, Cheng C, Li W, Li M, Ye S, Liu Z, Ding Y. Shi J, et al. Curr Pharm Des. 2025;31(33):2666-2690. doi: 10.2174/0113816128365423250126035306. Curr Pharm Des. 2025. PMID: 39949090

BACKGROUND: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease primarily characterized by insufficient insulin secretion or reduced insulin sensitivity in the body's cells, leading to persistently high blood glucose levels. Ganoderma lucidum triterpenoids, as i …

BACKGROUND: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease primarily characterized by insufficient insulin secretion or redu …

146

Racemic alkaloids from the fungus Ganoderma cochlear.

Wang XL, Dou M, Luo Q, Cheng LZ, Yan YM, Li RT, Cheng YX. Wang XL, et al. Fitoterapia. 2017 Jan;116:93-98. doi: 10.1016/j.fitote.2016.11.011. Epub 2016 Nov 25. Fitoterapia. 2017. PMID: 27894905

Seven pairs of new alkaloid enantiomers, ganocochlearines C-I (1, 3-8), and three pairs of known alkaloids were isolated from the fruiting bodies of Ganoderma cochlear. The chemical structures of new compounds were elucidated on the basis of 1D and 2D NMR data. ...

Seven pairs of new alkaloid enantiomers, ganocochlearines C-I (1, 3-8), and three pairs of known alkaloids were isolated from the fruiting b …

147

Potential mycotoxin production from Ganoderma boninense report by Nagappan et al. is premature.

Paterson RRM. Paterson RRM. Mol Biol Rep. 2024 Jul 30;51(1):868. doi: 10.1007/s11033-024-09702-3. Mol Biol Rep. 2024. PMID: 39080078 No abstract available.

148

Lanostane-type triterpenoids from the mycelial mat of Ganoderma lucidum and their hepatoprotective activities.

Zhang X, Gao X, Long G, Yang Y, Chen G, Hou G, Huo X, Jia J, Wang A, Hu G. Zhang X, et al. Phytochemistry. 2022 Jun;198:113131. doi: 10.1016/j.phytochem.2022.113131. Epub 2022 Mar 4. Phytochemistry. 2022. PMID: 35248578

Ganoderma lucidum (G. lucidum), a well-known Polyporaceae family fungus, is valued for its edibility and medicinal properties. ...

149

NMR-based Structural Classification, Identification, and Quantification of Triterpenoids from Edible Mushroom Ganoderma resinaceum.

Huang Y, Li X, Peng X, Adegoke AT, Chen J, Su H, Hu G, Wei G, Qiu M. Huang Y, et al. J Agric Food Chem. 2020 Mar 4;68(9):2816-2825. doi: 10.1021/acs.jafc.9b07791. Epub 2020 Feb 20. J Agric Food Chem. 2020. PMID: 32040905

Ganoderma mushrooms have been widely used as functional food in China, Japan, and Korea. Ganoderma triterpenoids are deemed to be the main functional constituents. The structures of Ganoderma triterpenoids are complex but quite similar, which makes their anal …

Ganoderma mushrooms have been widely used as functional food in China, Japan, and Korea. Ganoderma triterpenoids are deemed to …

150

Protective Effect of Ganoderma Triterpenoids on Cadmium-Induced Testicular Toxicity in Chickens.

Wang H, Zhang R, Song Y, Li T, Ge M. Wang H, et al. Biol Trace Elem Res. 2019 Jan;187(1):281-290. doi: 10.1007/s12011-018-1364-4. Epub 2018 May 2. Biol Trace Elem Res. 2019. PMID: 29717433

The control group was fed with normal full-fodder, the model group was fed with normal full-fodder with 140 mg/kg of CdCl(2), the Ganoderma triterpenoid treatment group was fed with a full-fodder diet containing 140 mg/kg of CdCl(2) and 0.5 mL of Ganoderma triterpen …

The control group was fed with normal full-fodder, the model group was fed with normal full-fodder with 140 mg/kg of CdCl(2), the Ganoder …

151

Triterpenoids from Ganoderma cochlear against inflammation and renal fibrosis.

Zhang JB, Li SH, Li ZY, Yan YM, Cheng YX. Zhang JB, et al. Fitoterapia. 2025 Jun;183:106543. doi: 10.1016/j.fitote.2025.106543. Epub 2025 Apr 14. Fitoterapia. 2025. PMID: 40233858

Seven new triterpenoids, fornicatins N - T (1-7), were isolated from Ganoderma cochlear. Their structures including absolute configurations were determined by 1D and 2D nuclear magnetic resonance (NMR) spectroscopy, computational methods, and HRESIMS. ...

Seven new triterpenoids, fornicatins N - T (1-7), were isolated from Ganoderma cochlear. Their structures including absolute configur …

152

Population genetics provides insights into the important agronomic traits of Ganoderma cultivation varieties in China.

Sun L, Li SD, Li Y, Wang L, Pu XM, Ge YP, Na Q, Li WH, Cheng XH. Sun L, et al. Gene. 2024 Jan 30;893:147938. doi: 10.1016/j.gene.2023.147938. Epub 2023 Oct 29. Gene. 2024. PMID: 38381508 Free article.

This study aimed to investigate the species diversity and genetic differentiation of the genome of the main cultivated strains of Ganoderma in China. Population genomics analysis was conducted based on 150 cultivated strains of Ganoderma collected nationwide. The re …

This study aimed to investigate the species diversity and genetic differentiation of the genome of the main cultivated strains of Ganoder …

153

Ganoderma lucidum suppresses growth of breast cancer cells through the inhibition of Akt/NF-kappaB signaling.

Jiang J, Slivova V, Harvey K, Valachovicova T, Sliva D. Jiang J, et al. Nutr Cancer. 2004;49(2):209-16. doi: 10.1207/s15327914nc4902_13. Nutr Cancer. 2004. PMID: 15489214

Ganoderma lucidum was also used in traditional Chinese medicine to prevent or treat a variety of diseases, including cancer. ...Here, we show that Ganoderma lucidum inhibits proliferation of breast cancer MDA-MB-231 cells by downregulating Akt/NF-kappaB signaling. . …

Ganoderma lucidum was also used in traditional Chinese medicine to prevent or treat a variety of diseases, including cancer. ...Here, …

154

Genome-Wide Characterization and Comparative Analysis of MYB Transcription Factors in Ganoderma Species.

Wang L, Huang Q, Zhang L, Wang Q, Liang L, Liao B. Wang L, et al. G3 (Bethesda). 2020 Aug 5;10(8):2653-2660. doi: 10.1534/g3.120.401372. G3 (Bethesda). 2020. PMID: 32471942 Free PMC article.

However, less is known about the functions of MYBs in Ganoderma In this study, five medicinal macrofungi of genus Ganoderma were subjected to a genome-wide comparative analysis of MYB genes. ...This comprehensive and systematic study of MYB family members provides a …

However, less is known about the functions of MYBs in Ganoderma In this study, five medicinal macrofungi of genus Ganoderma we …

155

Proteomic profiling of Ganoderma tsugae ethanol extract-induced adipogenesis displaying browning features.

Tseng HH, Yeh WC, Tu YC, Yang BF, Lai YT, Lee HK, Yang YC, Huang HC, Lee YJ, Ou CC, Kuo HP, Kuo YH, Kao MC, Liu JY. Tseng HH, et al. FEBS Lett. 2018 May;592(10):1643-1666. doi: 10.1002/1873-3468.13061. Epub 2018 May 11. FEBS Lett. 2018. PMID: 29683472 Free article.

Ganoderma is classified as a top grade traditional Chinese medicine for promoting human health by regulating 'vital energy'. Its potency towards metabolism and energy homeostasis, particularly, metabolic adaptations of adipocytes, needs to be re-evaluated through an eviden …

Ganoderma is classified as a top grade traditional Chinese medicine for promoting human health by regulating 'vital energy'. Its pote …

156

[Identification of phosphatidic acid interacting proteins in Ganoderma lingzhi].

Liu Y, Yin Y, Hao H, Wang R, He Z, Tian R, Liu G. Liu Y, et al. Sheng Wu Gong Cheng Xue Bao. 2021 Sep 25;37(9):3293-3299. doi: 10.13345/j.cjb.210275. Sheng Wu Gong Cheng Xue Bao. 2021. PMID: 34622636 Free article. Chinese.

Ganoderma lingzhi is widely recognized as a medicinal basidiomycetes. Triterpene acids (TAs) are the key bioactive medicinal components of G. lingzhi. ...

Ganoderma lingzhi is widely recognized as a medicinal basidiomycetes. Triterpene acids (TAs) are the key bioactive medicinal componen …

157

A new strategy to improve Ganoderma polysaccharides production by symbiotic fungi elicitors through activating the biosynthetic pathway.

Xu J, Yan X, Jia X, Wang Y, Xu H, Yu H, He L, Zheng B, Wu X. Xu J, et al. Int J Biol Macromol. 2023 Apr 30;235:123798. doi: 10.1016/j.ijbiomac.2023.123798. Epub 2023 Feb 24. Int J Biol Macromol. 2023. PMID: 36841391

Ganoderma lucidum polysaccharides (GLP) attract growing attention due to their remarkable bioactivities, but the low content in raw materials remains a bottleneck severely restricting their application. We previously found a higher polysaccharides accumulation in Ganode …

Ganoderma lucidum polysaccharides (GLP) attract growing attention due to their remarkable bioactivities, but the low content in raw m …

158

Meroterpenoids from the fruiting bodies of Ganoderma theaecolum.

Luo Q, Tu ZC, Yang ZL, Cheng YX. Luo Q, et al. Fitoterapia. 2018 Mar;125:273-280. doi: 10.1016/j.fitote.2018.01.015. Epub 2018 Feb 1. Fitoterapia. 2018. PMID: 29378219

A series of new terminal cyclohexane-type meroterpenoids, ganotheaecoloids A-N (1-6, 8-13, 15, and 16), along with three known ones (7, 14, and 17), were isolated from the dried fruiting bodies of Ganoderma theaecolum. Their chemical structures were identified by using spe …

A series of new terminal cyclohexane-type meroterpenoids, ganotheaecoloids A-N (1-6, 8-13, 15, and 16), along with three known ones (7, 14, …

159

Highly oxygenated lanostane triterpenoids from Ganoderma applanatum as a class of agents for inhibiting lipid accumulation in adipocytes.

Su HG, Wang Q, Zhou L, Peng XR, Xiong WY, Qiu MH. Su HG, et al. Bioorg Chem. 2020 Nov;104:104263. doi: 10.1016/j.bioorg.2020.104263. Epub 2020 Sep 3. Bioorg Chem. 2020. PMID: 32920365

Ganoderma triterpenoids (GTs), a class of major active constituents in Ganoderma species, play an important role in the anti-obesity effect of Ganoderma fungi. In the study, seventeen new highly oxygenated lanostane triterpenoids, ganoapplanoids A-Q (1-17), t …

Ganoderma triterpenoids (GTs), a class of major active constituents in Ganoderma species, play an important role in the anti-o …

160

COX-2 and iNOS inhibitory epimeric meroterpenoids from Ganoderma cochlear and structure revision of cochlearol Q.

Sura MB, Peng YL, Cai D, Cheng YX. Sura MB, et al. Fitoterapia. 2023 Jan;164:105390. doi: 10.1016/j.fitote.2022.105390. Epub 2022 Dec 10. Fitoterapia. 2023. PMID: 36513292

Four novel epimeric meroterpenoids, ganadone A (1), 3',10'-di-epi-ganadone A (2), 10'-epi-ganadone A (3), and 3'-epi-ganadone A (4) as well as another pairs of epimers, ganadone B (5) and 10'-epi-ganadone B (6), with a same basic skeleton compound ganadone C (7), together with tw …

Four novel epimeric meroterpenoids, ganadone A (1), 3',10'-di-epi-ganadone A (2), 10'-epi-ganadone A (3), and 3'-epi-ganadone A (4) as well …

161

Ganoderma neo-japonicum Imazeki revisited: Domestication study and antioxidant properties of its basidiocarps and mycelia.

Tan WC, Kuppusamy UR, Phan CW, Tan YS, Raman J, Anuar AM, Sabaratnam V. Tan WC, et al. Sci Rep. 2015 Jul 27;5:12515. doi: 10.1038/srep12515. Sci Rep. 2015. PMID: 26213331 Free PMC article.

Mushroom cultivation benefits humankind as it deliberately encourages wild mushrooms to be commercially propagated while recycling agricultural wastes. Ganoderma neo-japonicum is a rare polypore mushroom found growing on decaying Schizostachyum brachycladium (a tropical ba …

Mushroom cultivation benefits humankind as it deliberately encourages wild mushrooms to be commercially propagated while recycling agricultu …

162

The role of post-transcriptional modification on a new tRNA(Ile(GAU)) identified from Ganoderma lucidum in its fragments' cytotoxicity on cancer cells.

Ren F, Cao KY, Gong RZ, Yu ML, Tao P, Xiao Y, Jiang ZH. Ren F, et al. Int J Biol Macromol. 2023 Feb 28;229:885-895. doi: 10.1016/j.ijbiomac.2022.12.327. Epub 2023 Jan 2. Int J Biol Macromol. 2023. PMID: 36603719

Ganoderma lucidum (Ganoderma) is a famous Chinese herbal medicine which has been used clinically for thousands of years in China. Despite numerous studies on triterpenes and polysaccharides, the bioactivity of RNAs abundant in Ganoderma remains unknown. Here, …

Ganoderma lucidum (Ganoderma) is a famous Chinese herbal medicine which has been used clinically for thousands of years in Chi …

163

Pan-genomic characterization and structural variant analysis reveal insights into spore development and species diversity in Ganoderma.

Yu H, Wang S, Wang L, Wu W, Xu W, Wu S, Li X, Xu W, Huang Z, Lin Y, Wang H. Yu H, et al. Microb Genom. 2024 Nov;10(11):001328. doi: 10.1099/mgen.0.001328. Microb Genom. 2024. PMID: 39565084 Free PMC article.

Understanding the genomic diversity and functional implications of Ganoderma species is crucial for elucidating their evolutionary history and biotechnological potential. Here, we present the first pan-genomic analysis of Ganoderma spp., combining five newly sequenc …

Understanding the genomic diversity and functional implications of Ganoderma species is crucial for elucidating their evolutionary hi …

164

Elucidating wood decomposition by four species of Ganoderma from the United States.

Loyd AL, Held BW, Linder ER, Smith JA, Blanchette RA. Loyd AL, et al. Fungal Biol. 2018 Apr;122(4):254-263. doi: 10.1016/j.funbio.2018.01.006. Epub 2018 Feb 6. Fungal Biol. 2018. PMID: 29551199

The laccate (shiny or varnished) Ganoderma contain fungi that are important wood decay fungi of living trees and decomposers of woody debris. ...Laboratory decay microcosms (LDMs) were used to study the relative decay ability of G anoderma curtisii, Ganoderma meredi …

The laccate (shiny or varnished) Ganoderma contain fungi that are important wood decay fungi of living trees and decomposers of woody …

165

Anti-androgenic activities of Ganoderma lucidum.

Fujita R, Liu J, Shimizu K, Konishi F, Noda K, Kumamoto S, Ueda C, Tajiri H, Kaneko S, Suimi Y, Kondo R. Fujita R, et al. J Ethnopharmacol. 2005 Oct 31;102(1):107-12. doi: 10.1016/j.jep.2005.05.041. J Ethnopharmacol. 2005. PMID: 16029938

The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats. These results showed that Ganoderma lucidum might be a useful ingredient for the t …

The treatment of the fruit body of Ganoderma lucidum or the extract prepared from it significantly inhibited the testosterone-induced …

166

Characterization and Biological Studies of the Terpenoids from Ganoderma resinaceum and Serpula similis (Agaricomycetes).

Rikame TN, Ranawade PS, Mittal SPK, Barvkar VT, Borde MY, Tak RD. Rikame TN, et al. Int J Med Mushrooms. 2023;25(12):15-31. doi: 10.1615/IntJMedMushrooms.2023050771. Int J Med Mushrooms. 2023. PMID: 37947061

Mycochemical properties and bioactivities of Ganoderma resinaceum and Serpula similis remain unexplored. The present study assessed antioxidant, cytotoxicity, and cell migration abilities of Ganoderma and Serpula extracts, followed by their phytochemical analyses. . …

Mycochemical properties and bioactivities of Ganoderma resinaceum and Serpula similis remain unexplored. The present study assessed a …

167

Studies of Antioxidant and Cytotoxic Activity in Ready-to-Drink Wild Ganoderma Teas: An In Vitro Approach.

Ghosh S, Das S, Saha R, Acharya K. Ghosh S, et al. Int J Med Mushrooms. 2023;25(11):53-63. doi: 10.1615/IntJMedMushrooms.2023050232. Int J Med Mushrooms. 2023. PMID: 37831512

Ganoderma is a medicinally important mushroom and has been used since ancient times. However, mostly G. lucidum has been used for therapeutic purposes, in form of tea, dietary and drug supplements but other species of Ganoderma are still remaining underexploited. Th …

Ganoderma is a medicinally important mushroom and has been used since ancient times. However, mostly G. lucidum has been used for the …

168

An assessment of the genetic diversity within Ganoderma strains with AFLP and ITS PCR-RFLP.

Zheng L, Jia D, Fei X, Luo X, Yang Z. Zheng L, et al. Microbiol Res. 2009;164(3):312-21. doi: 10.1016/j.micres.2007.02.002. Epub 2007 Jul 16. Microbiol Res. 2009. PMID: 17629688 Free article.

Ganoderma lucidum is one of the most important medicinal materials and plant pathogens. ...The cluster analysis revealed that the taxonomical system of subgenus Ganoderma is composed of Sect. Ganoderma and Sect. Phaeonema, and the strain 22 should be a varian …

Ganoderma lucidum is one of the most important medicinal materials and plant pathogens. ...The cluster analysis revealed that the tax …

169

Meroterpenoid enantiomers from Ganoderma sinensis.

Cao WW, Luo Q, Cheng YX, Wang SM. Cao WW, et al. Fitoterapia. 2016 Apr;110:110-5. doi: 10.1016/j.fitote.2016.03.003. Epub 2016 Mar 3. Fitoterapia. 2016. PMID: 26947249

Zizhines A-F (1-6), six pairs of new meroterpenoid enantiomers and a known meroterpenoid (7) were isolated from the fruiting bodies of Ganoderma sinensis. The structures and absolute configurations of the new substances were assigned by spectroscopic and computational meth …

Zizhines A-F (1-6), six pairs of new meroterpenoid enantiomers and a known meroterpenoid (7) were isolated from the fruiting bodies of Ga …

170

Case report: Ganoderma weberianum invasive fungal disease (IFD) during allogeneic hematopoietic stem cell transplantation (HSCT).

Scott AP, Choptiany M, Dwyer J, McCarthy KL. Scott AP, et al. Transpl Infect Dis. 2021 Aug;23(4):e13647. doi: 10.1111/tid.13647. Epub 2021 Jun 13. Transpl Infect Dis. 2021. PMID: 34028924 No abstract available.

171

A new lanostane triterpenoid from Ganoderma resinaceum.

Yang Q, He K, Qiu S, Zheng A, Hu Q, Ma Z, Dong M, Zhou M. Yang Q, et al. J Asian Nat Prod Res. 2020 Nov;22(11):1095-1099. doi: 10.1080/10286020.2019.1674288. Epub 2019 Nov 22. J Asian Nat Prod Res. 2020. PMID: 31755308

A new 23,24,25,26,27-five-nortriterpenoid (1), named resinacein T, was isolated from an ethanol extract of the fruiting bodies in Ganoderma resinaceum of family Ganodermataceae, together with two known lanostane triterpenoids, 3beta,7beta,15alpha,24-tetrahydroxy-11,23-diox …

A new 23,24,25,26,27-five-nortriterpenoid (1), named resinacein T, was isolated from an ethanol extract of the fruiting bodies in Ganoder …

172

Lanostane triterpenoids from cultivated fruiting bodies of basidiomycete Ganoderma mbrekobenum.

Yangchum A, Fujii R, Choowong W, Rachtawee P, Pobkwamsuk M, Boonpratuang T, Mori S, Isaka M. Yangchum A, et al. Phytochemistry. 2022 Apr;196:113075. doi: 10.1016/j.phytochem.2021.113075. Epub 2021 Dec 31. Phytochemistry. 2022. PMID: 34974245

In the quest for medicinally active compounds in mushrooms of the genus Ganoderma, eleven undescribed lanostane triterpenoids, including a novel chlorinated derivative, i.e., (20S,24E)-21-chloro-15beta,20,29-trihydroxy-3,7,11-trioxolanosta-8,24-dien-26-oic acid, were isola …

In the quest for medicinally active compounds in mushrooms of the genus Ganoderma, eleven undescribed lanostane triterpenoids, includ …

173

Characterization of polysaccharides from Ganoderma spp. using saccharide mapping.

Wu DT, Xie J, Hu DJ, Zhao J, Li SP. Wu DT, et al. Carbohydr Polym. 2013 Sep 12;97(2):398-405. doi: 10.1016/j.carbpol.2013.04.101. Epub 2013 May 9. Carbohydr Polym. 2013. PMID: 23911463

The results showed that both 1,3-beta-D-glucosidic and 1,4-alpha-D-galactosiduronic linkages were existed in Lingzhi (Ganoderma lucidum and Ganoderma sinense), and the similarity of polysaccharides from G. lucidum and G. sinense was high, which may contribute to rat …

The results showed that both 1,3-beta-D-glucosidic and 1,4-alpha-D-galactosiduronic linkages were existed in Lingzhi (Ganoderma lucid …

174

Cytotoxic and N-Acetyltransferase Inhibitory Meroterpenoids from Ganoderma cochlear.

Cheng LZ, Qin FY, Ma XC, Wang SM, Yan YM, Cheng YX. Cheng LZ, et al. Molecules. 2018 Jul 20;23(7):1797. doi: 10.3390/molecules23071797. Molecules. 2018. PMID: 30037018 Free PMC article.

Seven compounds, including two pairs of new meroterpenoids, (+)- and (-)-gancochlearol C (1), (+)- and (-)-cochlearoid Q (3), and a new meroterpenoid gancochlearol D (2), together with four known meroterpenoids were isolated from the aqueous EtOH extract of the fruiting bodies of …

Seven compounds, including two pairs of new meroterpenoids, (+)- and (-)-gancochlearol C (1), (+)- and (-)-cochlearoid Q (3), and a new mero …

175

Significance of culture period on the physiochemistry and anti-cancer potentials of polysaccharides from mycelia of Ganoderma lucidum.

Qiu WL, Lo HC, Lu MK, Lin TY. Qiu WL, et al. Int J Biol Macromol. 2023 Jul 1;242(Pt 4):125181. doi: 10.1016/j.ijbiomac.2023.125181. Epub 2023 Jun 1. Int J Biol Macromol. 2023. PMID: 37270134

Ganoderma lucidum polysaccharides (GPS) have many functions. Polysaccharides are abundant in G. lucidum mycelia, but it is unclear whether the production and chemical characteristics of polysaccharides are related to the liquid cultural periods of mycelia. ...

Ganoderma lucidum polysaccharides (GPS) have many functions. Polysaccharides are abundant in G. lucidum mycelia, but it is unclear wh …

176

Ganoderma Triterpenoids Exert Antiatherogenic Effects in Mice by Alleviating Disturbed Flow-Induced Oxidative Stress and Inflammation.

Hsu PL, Lin YC, Ni H, Mo FE. Hsu PL, et al. Oxid Med Cell Longev. 2018 Apr 11;2018:3491703. doi: 10.1155/2018/3491703. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29849882 Free PMC article.

Ganoderma mushrooms, used in traditional Chinese medicine to promote health and longevity, have become widely accepted as herbal supplements. Ganoderma lucidum (GL), a commonly seen ganoderma species, is commercially cultivated under controlled conditions for …

Ganoderma mushrooms, used in traditional Chinese medicine to promote health and longevity, have become widely accepted as herbal supp …

177

Transcriptome analysis reveals insight into the protective effect of N-acetylcysteine against cadmium toxicity in Ganoderma lucidum (Polyporales: Polyporaceae).

Jin X, Wu P, Li P, Xiong C, Gui M, Huang W. Jin X, et al. Environ Sci Pollut Res Int. 2023 Apr;30(20):58436-58449. doi: 10.1007/s11356-023-26635-9. Epub 2023 Mar 29. Environ Sci Pollut Res Int. 2023. PMID: 36991205

Ganoderma lucidum is widely cultivated and used as traditional medicine in China and other Asian countries. As a member of macrofungi, Ganoderma lucidum is also prone to bioaccumulation of cadmium and other heavy metals in a polluted environment, which affects the g …

Ganoderma lucidum is widely cultivated and used as traditional medicine in China and other Asian countries. As a member of macrofungi …

178

Meroterpenoids with a large conjugated system from Ganoderma lucidum and their inhibitory activities against renal fibrosis.

Wang YX, Peng YL, Qiu B, Lv Q, Huang LS, Cheng YX. Wang YX, et al. Fitoterapia. 2022 Sep;161:105257. doi: 10.1016/j.fitote.2022.105257. Epub 2022 Jul 29. Fitoterapia. 2022. PMID: 35914706

Baoslingzhines A-E (1-5), five new meroterpenoids were isolated from the fruiting bodies of Ganoderma lucidum. The structures including their absolute configurations were characterized by using spectroscopic and computational methods. ...

Baoslingzhines A-E (1-5), five new meroterpenoids were isolated from the fruiting bodies of Ganoderma lucidum. The structures includi …

179

Ganoderma lucidum extract protects DNA from strand breakage caused by hydroxyl radical and UV irradiation.

Kim KC, Kim IG. Kim KC, et al. Int J Mol Med. 1999 Sep;4(3):273-7. Int J Mol Med. 1999. PMID: 10425278

The fruit bodies of Ganoderma lucidum have been used for the prevention and treatment of various diseases in the Orient. ...Our data suggest that Ganoderma mushroom merits investigation as a potential preventive agent in humans....

The fruit bodies of Ganoderma lucidum have been used for the prevention and treatment of various diseases in the Orient. ...Our data …

180

Enhanced polyethylene glycol (PEG)-mediated protoplast transformation system for the phytopathogenic fungus, Ganoderma boninense.

Lim FH, Rasid OA, Idris AS, As'wad AWM, Vadamalai G, Parveez GKA, Wong MY. Lim FH, et al. Folia Microbiol (Praha). 2021 Aug;66(4):677-688. doi: 10.1007/s12223-021-00852-6. Epub 2021 May 27. Folia Microbiol (Praha). 2021. PMID: 34041694

The basidiomycete fungus, Ganoderma boninense, has been identified as the main causal agent of oil palm basal stem rot (BSR) disease which has caused significant economic losses to the industry especially in Malaysia and Indonesia. ...

The basidiomycete fungus, Ganoderma boninense, has been identified as the main causal agent of oil palm basal stem rot (BSR) disease …

181

Five new compounds from the fungus Ganoderma petchii.

Dai WF, Guo PX, Tu ZC, Li RT, Cheng YX. Dai WF, et al. Fitoterapia. 2015 Oct;106:68-71. doi: 10.1016/j.fitote.2015.08.002. Epub 2015 Aug 12. Fitoterapia. 2015. PMID: 26277755

The fungal species of the genus Ganoderma attracted great interest in the last decades. Our recent investigation on Ganoderma petchii afforded five new compounds, (-)-petchioics A and B (1 and 2), petchiates A and B (3 and 4), petchine (5), and a known compound. ...

The fungal species of the genus Ganoderma attracted great interest in the last decades. Our recent investigation on Ganoderma …

182

Metabolic Profile of Scytalidium parasiticum-Ganoderma boninense Co-Cultures Revealed the Alkaloids, Flavonoids and Fatty Acids that Contribute to Anti-Ganoderma Activity.

Ahmad R, Lim CK, Marzuki NF, Goh YK, Azizan KA, Goh YK, Goh KJ, Ramzi AB, Baharum SN. Ahmad R, et al. Molecules. 2020 Dec 16;25(24):5965. doi: 10.3390/molecules25245965. Molecules. 2020. PMID: 33339375 Free PMC article.

In solving the issue of basal stem rot diseases caused by Ganoderma, an investigation of Scytalidium parasiticum as a biological control agent that suppresses Ganoderma infection has gained our interest, as it is more environmentally friendly. ...This comprehensive …

In solving the issue of basal stem rot diseases caused by Ganoderma, an investigation of Scytalidium parasiticum as a biological cont …

183

Ganoderma tsugae extracts inhibit colorectal cancer cell growth via G(2)/M cell cycle arrest.

Hsu SC, Ou CC, Li JW, Chuang TC, Kuo HP, Liu JY, Chen CS, Lin SC, Su CH, Kao MC. Hsu SC, et al. J Ethnopharmacol. 2008 Dec 8;120(3):394-401. doi: 10.1016/j.jep.2008.09.025. Epub 2008 Oct 2. J Ethnopharmacol. 2008. PMID: 18951965

AIM OF THE STUDY: To investigate the inhibitory activity and explore the molecular mechanisms of anti-tumor effect on colorectal cancer cells in vitro and in vivo as well as to test the side effects of Ganoderma tsugae. MATERIALS AND METHODS: Methanol fraction was obtained …

AIM OF THE STUDY: To investigate the inhibitory activity and explore the molecular mechanisms of anti-tumor effect on colorectal cancer cell …

184

Comparative genomics reveals ample evidence to Ganoderma sinense cultivars for molecular identification and new FIP exploration.

Chen TQ, Xu XL, Yang C, Yang L, Ying ZH, Shi XK, Ding MG. Chen TQ, et al. Genomics. 2024 Sep;116(5):110924. doi: 10.1016/j.ygeno.2024.110924. Epub 2024 Aug 22. Genomics. 2024. PMID: 39178996 Free article.

The first dikaryotic genome of Ganoderma cultivar Zizhi S2 (56.76 Mb, 16,681 genes) has been sequenced recently. 98.15% of complete BUSCOs were recovered in this genome assembly and high-confidence annotation rate improved to 91.41%. ...So that, this cultivar Zizhi S2 is c …

The first dikaryotic genome of Ganoderma cultivar Zizhi S2 (56.76 Mb, 16,681 genes) has been sequenced recently. 98.15% of complete B …

185

Biotransformation of triterpenoid ganoderic acids from exogenous diterpene dihydrotanshinone I in the cultures of Ganoderma sessile.

Wang X, Wu H, Wong KH, Wang Y, Chen B, Feng K. Wang X, et al. Microb Cell Fact. 2023 Jul 28;22(1):139. doi: 10.1186/s12934-023-02156-5. Microb Cell Fact. 2023. PMID: 37507727 Free PMC article.

In this work, triterpenoids, ganoderic acids (GAs) were discovered to be produced via biotransformation of a diterpene, 15,16-dihydrotanshinone I (DHT) in the liquid cultured Ganoderma sessile mycelium. RESULTS: Firstly, the biotransformation products, two rare GAs were is …

In this work, triterpenoids, ganoderic acids (GAs) were discovered to be produced via biotransformation of a diterpene, 15,16-dihydrotanshin …

186

Simple and robust differentiation of Ganoderma species by high performance thin-layer chromatography coupled with single quadrupole mass spectrometry QDa.

Yao S, Zhang JQ, Hou JJ, Hu XS, Wang L, DA J, Rao W, Wang DD, Huang Y, Wu WY, Guo DA. Yao S, et al. Chin J Nat Med. 2021 Apr;19(4):295-304. doi: 10.1016/S1875-5364(21)60030-4. Chin J Nat Med. 2021. PMID: 33875169

In this study, a high performance thin-layer chromatography/single quadrupole mass spectrometry QDa (HPTLC-QDa) method for robust authentication of Ganoderma lucidum, a popular and valuable herbal medicine, has been developed. This method is simple and practical, which all …

In this study, a high performance thin-layer chromatography/single quadrupole mass spectrometry QDa (HPTLC-QDa) method for robust authentica …

187

Alkaloids, sesquiterpenoids and hybrids of terpenoid with p-hydroxycinnamic acid from Ganoderma sinensis and their biological evaluation.

Luo Q, Cao WW, Cheng YX. Luo Q, et al. Phytochemistry. 2022 Nov;203:113379. doi: 10.1016/j.phytochem.2022.113379. Epub 2022 Aug 25. Phytochemistry. 2022. PMID: 36029844

The fruiting bodies of Ganoderma sinensis are used as food raw materials of marketed healthcare products. To gain an insight into the chemical and biological profling of G. sinensis, twenty-five compounds including eleven undescribed ones (ganodermasines A-K) and fourteen …

The fruiting bodies of Ganoderma sinensis are used as food raw materials of marketed healthcare products. To gain an insight into the …

188

Response of intestinal metabolome to polysaccharides from mycelia of Ganoderma lucidum.

Jin M, Zhang H, Wang J, Shao D, Yang H, Huang Q, Shi J, Xu C, Zhao K. Jin M, et al. Int J Biol Macromol. 2019 Feb 1;122:723-731. doi: 10.1016/j.ijbiomac.2018.10.224. Epub 2018 Nov 2. Int J Biol Macromol. 2019. PMID: 30395901

Polysaccharides from the mycelia of Ganoderma lucidum (GLP) can improve intestinal barrier function, regulate intestinal immunity and modulate intestinal microbiota. ...

Polysaccharides from the mycelia of Ganoderma lucidum (GLP) can improve intestinal barrier function, regulate intestinal immunity and …

189

Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin.

Zhao S, Ye G, Fu G, Cheng JX, Yang BB, Peng C. Zhao S, et al. Int J Oncol. 2011 May;38(5):1319-27. doi: 10.3892/ijo.2011.965. Epub 2011 Mar 8. Int J Oncol. 2011. PMID: 21399867

In this study, we determined whether Ganoderma lucidum regulates EOC cell activity. Using several cell lines derived from EOC, we found that Ganoderma lucidum strongly decreased cell numbers in a dose-dependent manner. Ganoderma lucidum also inhibited colony …

In this study, we determined whether Ganoderma lucidum regulates EOC cell activity. Using several cell lines derived from EOC, we fou …

190

Progression Over Time of Nutritional Content and Antioxidant Activity of Grains Fermented with the Medicinal Mushrooms Pleurotus ostreatus and Ganoderma sessile (Agaricomycetes).

Mazzola A, Kuhar F, Greslebin AG. Mazzola A, et al. Int J Med Mushrooms. 2024;26(10):55-67. doi: 10.1615/IntJMedMushrooms.2024054939. Int J Med Mushrooms. 2024. PMID: 39171631

This article reports the variation over time in nutritional, polyphenol, and triterpene contents, as well as the antioxidant activity of rice and wheat fermented with Ganoderma sessile and Pleurotus ostreatus. Solid-state fermentation significantly improved the antioxidant …

This article reports the variation over time in nutritional, polyphenol, and triterpene contents, as well as the antioxidant activity of ric …

191

Elucidating "lucidum": Distinguishing the diverse laccate Ganoderma species of the United States.

Loyd AL, Barnes CW, Held BW, Schink MJ, Smith ME, Smith JA, Blanchette RA. Loyd AL, et al. PLoS One. 2018 Jul 18;13(7):e0199738. doi: 10.1371/journal.pone.0199738. eCollection 2018. PLoS One. 2018. PMID: 30020945 Free PMC article.

For the past century, many studies of Ganoderma in North America and other regions of the world have used the name G. lucidum sensu lato for any laccate (shiny or varnished) Ganoderma species growing on hardwood trees or substrates. ...Overall, this study clarifies …

For the past century, many studies of Ganoderma in North America and other regions of the world have used the name G. lucidum sensu l …

192

Rapid differentiation of Ganoderma species by direct ionization mass spectrometry.

Wong HY, Wong MY, Hu B, So PK, Chan CO, Mok DK, Yao ZP. Wong HY, et al. Anal Chim Acta. 2018 Jan 25;999:99-106. doi: 10.1016/j.aca.2017.11.006. Epub 2017 Nov 9. Anal Chim Acta. 2018. PMID: 29254579

Rapid differentiation of the Ganoderma species that are officially stated in the Chinese pharmacopoeia from easily confused Ganoderma species could be achieved based on this method, as the acquired DI-MS spectra showed that ganoderic acids, the major active componen …

Rapid differentiation of the Ganoderma species that are officially stated in the Chinese pharmacopoeia from easily confused Ganode …

193

Three new triterpenoids from Ganoderma theaecolum.

Liu LY, Yan Z, Kang J, Chen RY, Yu DQ. Liu LY, et al. J Asian Nat Prod Res. 2017 Sep;19(9):847-853. doi: 10.1080/10286020.2016.1271793. Epub 2017 Feb 2. J Asian Nat Prod Res. 2017. PMID: 28152606

Three new triterpenoids (1-3), together with four known triterpenoids (4-7), were isolated from the fruiting bodies of Ganoderma theaecolum. Their structures were elucidated on the basis of their spectroscopic data and chemical evidence. ...

Three new triterpenoids (1-3), together with four known triterpenoids (4-7), were isolated from the fruiting bodies of Ganoderma thea …

194

Identification of non-ribosomal peptide synthetase in Ganoderma boninense Pat. that was expressed during the interaction with oil palm.

Shokrollahi N, Ho CL, Zainudin NAIM, Wahab MABA, Wong MY. Shokrollahi N, et al. Sci Rep. 2021 Aug 11;11(1):16330. doi: 10.1038/s41598-021-95549-8. Sci Rep. 2021. PMID: 34381084 Free PMC article.

Basal stem rot (BSR) of oil palm is a disastrous disease caused by a white-rot fungus Ganoderma boninense Pat. Non-ribosomal peptides (NRPs) synthesized by non-ribosomal peptide synthetases (NRPSs) are a group of secondary metabolites that act as fungal virulent factors du …

Basal stem rot (BSR) of oil palm is a disastrous disease caused by a white-rot fungus Ganoderma boninense Pat. Non-ribosomal peptides …

195

Assessment of redox homeostasis via genotoxicity, cytotoxicity, apoptosis and NRF-2 in colorectal cancer cell lines after treatment with Ganoderma lucidum extract.

Tülüce Y, Keleş AY, Köstekci S. Tülüce Y, et al. Drug Chem Toxicol. 2024 Sep;47(5):693-709. doi: 10.1080/01480545.2023.2257403. Epub 2023 Sep 13. Drug Chem Toxicol. 2024. PMID: 37700682

The results showed that Ganoderma lucidum mushroom extract reduces cell proliferation, colony formation, and NRF-2, induces DNA damage, slows cell migration, and increases oxidative stress. This study shows that Ganoderma lucidum mushroom extract reduces cell prolif …

The results showed that Ganoderma lucidum mushroom extract reduces cell proliferation, colony formation, and NRF-2, induces DNA damag …

196

Tubulin polymerization-stimulating activity of Ganoderma triterpenoids.

Kohno T, Hai-Bang T, Zhu Q, Amen Y, Sakamoto S, Tanaka H, Morimoto S, Shimizu K. Kohno T, et al. J Nat Med. 2017 Apr;71(2):457-462. doi: 10.1007/s11418-017-1072-y. Epub 2017 Jan 11. J Nat Med. 2017. PMID: 28078535

This study was conducted to evaluate the effect of Ganoderma triterpenoids on tubulin polymerization. A total of twenty-four compounds were investigated using an in vitro tubulin polymerization assay. ...These findings would be helpful for further studies on the potential …

This study was conducted to evaluate the effect of Ganoderma triterpenoids on tubulin polymerization. A total of twenty-four compound …

197

A General Entry to Ganoderma Meroterpenoids: Synthesis of Applanatumol E, H, and I, Lingzhilactone B, Meroapplanin B, and Lingzhiol.

Rode A, Müller N, Kováč O, Wurst K, Magauer T. Rode A, et al. Org Lett. 2024 Oct 25;26(42):9017-9021. doi: 10.1021/acs.orglett.4c03192. Epub 2024 Oct 11. Org Lett. 2024. PMID: 39392896 Free PMC article.

Ganoderma meroterpenoids are fungal derived hybrid natural product class containing a 1,2,4-trisubstituted benzene ring and a polycyclic terpenoid part. ...

Ganoderma meroterpenoids are fungal derived hybrid natural product class containing a 1,2,4-trisubstituted benzene ring and a polycyc …

198

Global diversity of the Ganoderma lucidum complex (Ganodermataceae, Polyporales) inferred from morphology and multilocus phylogeny.

Zhou LW, Cao Y, Wu SH, Vlasák J, Li DW, Li MJ, Dai YC. Zhou LW, et al. Phytochemistry. 2015 Jun;114:7-15. doi: 10.1016/j.phytochem.2014.09.023. Epub 2014 Oct 25. Phytochemistry. 2015. PMID: 25453909

Species of the Ganoderma lucidum complex are used in many types of health products. However, the taxonomy of this complex has long been chaotic, thus limiting its uses. ...These 13 species were not strongly supported as a single monophyletic lineage, and were further group …

Species of the Ganoderma lucidum complex are used in many types of health products. However, the taxonomy of this complex has long be …

199

Biodegradation of polycyclic aromatic hydrocarbons by native Ganoderma sp. strains: identification of metabolites and proposed degradation pathways.

Torres-Farradá G, Manzano-León AM, Rineau F, Ramos Leal M, Thijs S, Jambon I, Put J, Czech J, Guerra Rivera G, Carleer R, Vangronsveld J. Torres-Farradá G, et al. Appl Microbiol Biotechnol. 2019 Sep;103(17):7203-7215. doi: 10.1007/s00253-019-09968-9. Epub 2019 Jun 29. Appl Microbiol Biotechnol. 2019. PMID: 31256229

The potential of well-adapted indigenous Ganoderma strains to degrade PAHs remains underexplored. Seven native Ganoderma sp. strains with capacity to produce high levels of laccase enzymes and to degrade synthetic dyes were investigated for their degradation potenti …

The potential of well-adapted indigenous Ganoderma strains to degrade PAHs remains underexplored. Seven native Ganoderma sp. s …

200

Ganoderma basidiospores in the air in relation to land cover and weather patterns in a temperate climate zone.

Wójcik-Kanach M, Kasprzyk I. Wójcik-Kanach M, et al. Fungal Biol. 2025 Apr;129(2):101542. doi: 10.1016/j.funbio.2025.101542. Epub 2025 Jan 17. Fungal Biol. 2025. PMID: 40023525

The aim of the work was a spatiotemporal analysis of the concentration of Ganoderma spores in the air of a city and a village in a transitional temperate climate. ...The research confirms the hypothesis that land development, weather factors, and the altitude at which moni …

The aim of the work was a spatiotemporal analysis of the concentration of Ganoderma spores in the air of a city and a village in a tr …

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