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Gap-junction-mediated cell-to-cell communication.
Hervé JC, Derangeon M. Hervé JC, et al. Cell Tissue Res. 2013 Apr;352(1):21-31. doi: 10.1007/s00441-012-1485-6. Epub 2012 Sep 1. Cell Tissue Res. 2013. PMID: 22940728 Review.
These channels are densely packed into plasma-membrane spatial microdomains termed "gap junctions" and allow cells to exchange ions and small molecules directly. A hemichannel is a hexameric torus of junctional proteins around an aqueous pore. Vertebrates express tw …
These channels are densely packed into plasma-membrane spatial microdomains termed "gap junctions" and allow cells to exchange …
Gap Junction Channels of Innexins and Connexins: Relations and Computational Perspectives.
Sánchez A, Castro C, Flores DL, Gutiérrez E, Baldi P. Sánchez A, et al. Int J Mol Sci. 2019 May 19;20(10):2476. doi: 10.3390/ijms20102476. Int J Mol Sci. 2019. PMID: 31109150 Free PMC article. Review.
Gap junction (GJ) channels in invertebrates have been used to understand cell-to-cell communication in vertebrates. ...Dysregulation and structural alteration of the gap junction-mediated communication have been proven to be associated with a myriad of …
Gap junction (GJ) channels in invertebrates have been used to understand cell-to-cell communication in vertebrates. ...Dysregu …
Targeting gap junction in epilepsy: Perspectives and challenges.
Li Q, Li QQ, Jia JN, Liu ZQ, Zhou HH, Mao XY. Li Q, et al. Biomed Pharmacother. 2019 Jan;109:57-65. doi: 10.1016/j.biopha.2018.10.068. Epub 2018 Nov 2. Biomed Pharmacother. 2019. PMID: 30396092 Free article. Review.
Gap junctions (GJs) are multiple cellular intercellular connections that allow ions to pass directly into the cytoplasm of neighboring cells. ...
Gap junctions (GJs) are multiple cellular intercellular connections that allow ions to pass directly into the cytoplasm of nei …
Gap junction gene and protein families: Connexins, innexins, and pannexins.
Beyer EC, Berthoud VM. Beyer EC, et al. Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):5-8. doi: 10.1016/j.bbamem.2017.05.016. Epub 2017 May 27. Biochim Biophys Acta Biomembr. 2018. PMID: 28559187 Free PMC article. Review.
Gap junction channels facilitate the intercellular exchange of ions and small molecules. While this process is critical to all multicellular organisms, the proteins that form gap junction channels are not conserved. Vertebrate gap junctions …
Gap junction channels facilitate the intercellular exchange of ions and small molecules. While this process is critical to all …
Structural insights into gap junction channels boosted by cryo-EM.
Oshima A. Oshima A. Curr Opin Struct Biol. 2020 Aug;63:42-48. doi: 10.1016/j.sbi.2020.03.008. Epub 2020 Apr 24. Curr Opin Struct Biol. 2020. PMID: 32339861 Free article. Review.
Regulating intercellular communication is essential for multicellular organisms. Gap junction channels are the major components mediating this function, but the molecular mechanisms underlying their opening and closing remain unclear. ...This review focuses on recen …
Regulating intercellular communication is essential for multicellular organisms. Gap junction channels are the major component …
Gap junction proteins are key drivers of endocrine function.
Meda P. Meda P. Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):124-140. doi: 10.1016/j.bbamem.2017.03.005. Epub 2017 Mar 8. Biochim Biophys Acta Biomembr. 2018. PMID: 28284720 Free article. Review.
It has long been known that the main secretory cells of exocrine and endocrine glands are connected by gap junctions, made by a variety of connexin species that ensure their electrical and metabolic coupling. ...This article is part of a Special Issue entitled: G …
It has long been known that the main secretory cells of exocrine and endocrine glands are connected by gap junctions, made by …
Accessing gap-junction channel structure-function relationships through molecular modeling and simulations.
Villanelo F, Escalona Y, Pareja-Barrueto C, Garate JA, Skerrett IM, Perez-Acle T. Villanelo F, et al. BMC Cell Biol. 2017 Jan 17;18(Suppl 1):5. doi: 10.1186/s12860-016-0121-9. BMC Cell Biol. 2017. PMID: 28124624 Free PMC article. Review.
BACKGROUND: Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. ...RESULTS AND DISCUSSION: By comparing results obtained by molecular modeling and simulations techniques with structural and functional information obt …
BACKGROUND: Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. ...RESULTS A …
Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications.
Totland MZ, Rasmussen NL, Knudsen LM, Leithe E. Totland MZ, et al. Cell Mol Life Sci. 2020 Feb;77(4):573-591. doi: 10.1007/s00018-019-03285-0. Epub 2019 Sep 9. Cell Mol Life Sci. 2020. PMID: 31501970 Free PMC article. Review.
Gap junctions consist of arrays of intercellular channels that enable adjacent cells to communicate both electrically and metabolically. ...Gap junctions are highly dynamic structures and by modulating the turnover rate of connexins, cells can rapidly …
Gap junctions consist of arrays of intercellular channels that enable adjacent cells to communicate both electrically and meta …
Gap junction channel gating.
Bukauskas FF, Verselis VK. Bukauskas FF, et al. Biochim Biophys Acta. 2004 Mar 23;1662(1-2):42-60. doi: 10.1016/j.bbamem.2004.01.008. Biochim Biophys Acta. 2004. PMID: 15033578 Free PMC article. Review.
Over the last two decades, the view of gap junction (GJ) channel gating has changed from one with GJs having a single transjunctional voltage-sensitive (V(j)-sensitive) gating mechanism to one with each hemichannel of a formed GJ channel, as well as unapposed hemich …
Over the last two decades, the view of gap junction (GJ) channel gating has changed from one with GJs having a single transjun …
Structure of an innexin gap junction channel and cryo-EM sample preparation.
Oshima A. Oshima A. Microscopy (Oxf). 2017 Dec 1;66(6):371-379. doi: 10.1093/jmicro/dfx035. Microscopy (Oxf). 2017. PMID: 29036409 Free PMC article. Review.
Gap junction channels are essential for mediating intercellular communication in most multicellular organisms. ...This review summarizes cutting-edge progress toward determining an innexin gap junction channel structure, as well as essential tips for p …
Gap junction channels are essential for mediating intercellular communication in most multicellular organisms. ...This review …
23,858 results
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