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Year Number of Results
2014 2
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2017 5
2018 2
2019 4
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2023 4
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27 results

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Page 1
Integrative clinical genomics of advanced prostate cancer.
Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM. Robinson D, et al. Cell. 2015 May 21;161(5):1215-1228. doi: 10.1016/j.cell.2015.05.001. Cell. 2015. PMID: 26000489 Free PMC article.
Aberrations of AR, ETS genes, TP53, and PTEN were frequent (40%-60% of cases), with TP53 and AR alterations enriched in mCRPC compared to primary prostate cancer. We identified new genomic alterations in PIK3CA/B, R-spondin, BRAF/RAF1, APC, beta-catenin, and ZBTB16/PLZF. M …
Aberrations of AR, ETS genes, TP53, and PTEN were frequent (40%-60% of cases), with TP53 and AR alterations enriched in mCRPC compared to pr …
CD38 in Advanced Prostate Cancers.
Guo C, Crespo M, Gurel B, Dolling D, Rekowski J, Sharp A, Petremolo A, Sumanasuriya S, Rodrigues DN, Ferreira A, Pereira R, Figueiredo I, Mehra N, Lambros MBK, Neeb A, Gil V, Seed G, Terstappen L, Alimonti A, Drake CG, Yuan W, de Bono JS; International SU2C PCF Prostate Cancer Dream Team. Guo C, et al. Eur Urol. 2021 Jun;79(6):736-746. doi: 10.1016/j.eururo.2021.01.017. Epub 2021 Mar 5. Eur Urol. 2021. PMID: 33678520 Free PMC article.
OBJECTIVE: To characterise CD38 expression on prostate cancer (PC) epithelial cells and TIICs, and to associate this expression with clinical outcomes. DESIGN, SETTING, AND PARTICIPANTS: RNAseq from 159 patients with metastatic castration-resistant prostate cancer ( …
OBJECTIVE: To characterise CD38 expression on prostate cancer (PC) epithelial cells and TIICs, and to associate this expression with …
Targeted radionuclide therapy: frontiers in theranostics.
Gallivanone F, Valente M, Savi A, Canevari C, Castiglioni I. Gallivanone F, et al. Front Biosci (Landmark Ed). 2017 Jun 1;22(10):1750-1759. doi: 10.2741/4569. Front Biosci (Landmark Ed). 2017. PMID: 28410143 Free article. Review.
Effects of a differentiating therapy on cancer-stem-cell-driven tumors.
Fotinós J, Barberis L, Condat CA. Fotinós J, et al. J Theor Biol. 2023 Sep 7;572:111563. doi: 10.1016/j.jtbi.2023.111563. Epub 2023 Jun 28. J Theor Biol. 2023. PMID: 37391126
The growth of many solid tumors has been found to be driven by chemo- and radiotherapy-resistant cancer stem cells (CSCs). A suitable therapeutic avenue in these cases may involve the use of a differentiating agent (DA) to force the differentiation of the CSCs and of conve …
The growth of many solid tumors has been found to be driven by chemo- and radiotherapy-resistant cancer stem cells (CSCs). A suitable …
Magnetic layered double hydroxides with carbamazepine for breast cancer treatment.
Peralta MF, Mendieta SN, Scolari IR, Gerbaldo MV, Oliva MI, Gil GA, Granero GE, Crivello ME. Peralta MF, et al. Heliyon. 2023 Oct 14;9(10):e21030. doi: 10.1016/j.heliyon.2023.e21030. eCollection 2023 Oct. Heliyon. 2023. PMID: 37916071 Free PMC article.
Current cancer chemotherapy is associated with many side effects and, in some cases, drug resistance, which makes the search for new active molecules and drug delivery strategies imperative. ...Carbamazepine administered with magnetic clays as a carrier is a promising trea …
Current cancer chemotherapy is associated with many side effects and, in some cases, drug resistance, which makes the search for new …
Integrative Clinical Genomics of Advanced Prostate Cancer.
Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Sboner A, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM. Robinson D, et al. Cell. 2015 Jul 16;162(2):454. doi: 10.1016/j.cell.2015.06.053. Epub 2015 Jul 16. Cell. 2015. PMID: 28843286 Free article. No abstract available.
Smart material based on boron crosslinked polymers with potential applications in cancer radiation therapy.
Vedelago J, Mattea F, Triviño S, Montesinos MDM, Keil W, Valente M, Romero M. Vedelago J, et al. Sci Rep. 2021 Jun 10;11(1):12269. doi: 10.1038/s41598-021-91413-x. Sci Rep. 2021. PMID: 34112821 Free PMC article.
Organoboron compounds have been playing an increasingly important role in analytical chemistry, material science, health applications, and particularly as functional polymers like boron carriers for cancer therapy. There are two main applications of boron isotopes in radia …
Organoboron compounds have been playing an increasingly important role in analytical chemistry, material science, health applications, and p …
Understanding the influence of substrate when growing tumorspheres.
Benítez L, Barberis L, Vellón L, Condat CA. Benítez L, et al. BMC Cancer. 2021 Mar 15;21(1):276. doi: 10.1186/s12885-021-07918-1. BMC Cancer. 2021. PMID: 33722191 Free PMC article.
We find that, in the presence of stem cell growth factors, the interspecific cooperation between cancer stem cells and differentiated cancer cells induces a positive feedback loop that determines growth, independently of substrate hardness. ...A specific condition f …
We find that, in the presence of stem cell growth factors, the interspecific cooperation between cancer stem cells and differentiated …
27 results