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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
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26 results

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Page 1
Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.
Ishihara T, Ariizumi Y, Shiga A, Kato T, Tan CF, Sato T, Miki Y, Yokoo M, Fujino T, Koyama A, Yokoseki A, Nishizawa M, Kakita A, Takahashi H, Onodera O. Ishihara T, et al. Hum Mol Genet. 2013 Oct 15;22(20):4136-47. doi: 10.1093/hmg/ddt262. Epub 2013 Jun 4. Hum Mol Genet. 2013. PMID: 23740936
Disappearance of TAR-DNA-binding protein 43 kDa (TDP-43) from the nucleus contributes to the pathogenesis of amyotrophic lateral sclerosis (ALS), but the nuclear function of TDP-43 is not yet fully understood. TDP-43 associates with nuclear bodies including Gemini o …
Disappearance of TAR-DNA-binding protein 43 kDa (TDP-43) from the nucleus contributes to the pathogenesis of amyotrophic lateral sclerosis ( …
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.
Shan X, Chiang PM, Price DL, Wong PC. Shan X, et al. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16325-30. doi: 10.1073/pnas.1003459107. Epub 2010 Aug 24. Proc Natl Acad Sci U S A. 2010. PMID: 20736350 Free PMC article.
Whereas an elevated level of TDP-43 disrupts the normal nuclear distribution of survival motor neuron (SMN)-associated Gemini of coiled bodies (GEMs) in motor neurons, its absence prevents the formation of GEMs in the nuclei of these cells. ...
Whereas an elevated level of TDP-43 disrupts the normal nuclear distribution of survival motor neuron (SMN)-associated Gemini of c …
Coiled bodies and gems: Janus or gemini?
Matera AG, Frey MR. Matera AG, et al. Am J Hum Genet. 1998 Aug;63(2):317-21. doi: 10.1086/301992. Am J Hum Genet. 1998. PMID: 9683623 Free PMC article. Review. No abstract available.
[Molecular Pathogenesis of Amyotrophic Lateral Sclerosis].
Tsuboguchi S, Ishihara T, Sugai A, Yokoseki A, Onodera O. Tsuboguchi S, et al. Brain Nerve. 2019 Nov;71(11):1183-1189. doi: 10.11477/mf.1416201428. Brain Nerve. 2019. PMID: 31722304 Japanese.
The formation of cytoplasmic inclusions results in the loss of TDP-43 from the nucleus, resulting in abnormalities in RNA metabolism, through the alteration of spliceosomes and Gemini of coiled bodies. Furthermore, in ALS, the regulation of TDP-43 mRNA/protei …
The formation of cytoplasmic inclusions results in the loss of TDP-43 from the nucleus, resulting in abnormalities in RNA metabolism, throug …
Linker Length-Dependent Control of Gemini Surfactant Aqueous Lyotropic Gyroid Phase Stability.
Perroni DV, Baez-Cotto CM, Sorenson GP, Mahanthappa MK. Perroni DV, et al. J Phys Chem Lett. 2015 Mar 19;6(6):993-8. doi: 10.1021/acs.jpclett.5b00092. Epub 2015 Mar 5. J Phys Chem Lett. 2015. PMID: 26262858 Free article.
However, few known surfactants enable access to these mesophases over wide temperature and amphiphile concentration phase windows. Recent studies have demonstrated that gemini ("twin tail") dicarboxylate surfactants, in which alkyl carboxylates are covalently linked near t …
However, few known surfactants enable access to these mesophases over wide temperature and amphiphile concentration phase windows. Recent st …
[Mystic gems].
BOEHNE C. BOEHNE C. Med Welt. 1962 Mar 10;10:553-4. Med Welt. 1962. PMID: 13870474 German. No abstract available.
Minor splicing pathway is not minor any more: implications for the pathogenesis of motor neuron diseases.
Onodera O, Ishihara T, Shiga A, Ariizumi Y, Yokoseki A, Nishizawa M. Onodera O, et al. Neuropathology. 2014 Feb;34(1):99-107. doi: 10.1111/neup.12070. Epub 2013 Sep 22. Neuropathology. 2014. PMID: 24112438 Review.
TDP-43 is a nuclear protein that colocalizes with Cajal body or Gem in cultured cells. Several recent studies have reported that the decreasing number of Gems accompanied the depletion of the causative genes for ALS, TDP-43 and FUS. ...Although the molecular mechanisms und …
TDP-43 is a nuclear protein that colocalizes with Cajal body or Gem in cultured cells. Several recent studies have reported that the …
The spinal muscular atrophy disease gene product, SMN: A link between snRNP biogenesis and the Cajal (coiled) body.
Carvalho T, Almeida F, Calapez A, Lafarga M, Berciano MT, Carmo-Fonseca M. Carvalho T, et al. J Cell Biol. 1999 Nov 15;147(4):715-28. doi: 10.1083/jcb.147.4.715. J Cell Biol. 1999. PMID: 10562276 Free PMC article.
It was previously reported that in HeLa cells, SMN and SIP1 form discrete foci located next to Cajal (coiled) bodies, the so-called "gemini of coiled bodies" or "gems." An intriguing feature of gems is that they do not appear to contain snRNPs. …
It was previously reported that in HeLa cells, SMN and SIP1 form discrete foci located next to Cajal (coiled) bodies, the so-c …
Higher order arrangement of the eukaryotic nuclear bodies.
Wang IF, Reddy NM, Shen CK. Wang IF, et al. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13583-8. doi: 10.1073/pnas.212483099. Epub 2002 Oct 2. Proc Natl Acad Sci U S A. 2002. PMID: 12361981 Free PMC article.
Through the analysis of TDP, a protein functional in both transcriptional repression and alternative splicing, we have identified a new category of nuclear bodies within which the TDP molecules reside. Remarkably, the TDP bodies (TBs) colocalize or overlap with seve …
Through the analysis of TDP, a protein functional in both transcriptional repression and alternative splicing, we have identified a new cate …
26 results