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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 17
1947 4
1948 9
1949 7
1950 12
1951 27
1952 26
1953 23
1954 16
1955 31
1956 32
1957 36
1958 40
1959 49
1960 69
1961 56
1962 54
1963 38
1964 44
1965 49
1966 8
1967 11
1968 29
1969 27
1970 28
1971 59
1972 67
1973 114
1974 96
1975 174
1976 225
1977 168
1978 173
1979 230
1980 220
1981 247
1982 279
1983 304
1984 381
1985 440
1986 441
1987 480
1988 520
1989 790
1990 1065
1991 1243
1992 1624
1993 2563
1994 2663
1995 3474
1996 3908
1997 4556
1998 5248
1999 6155
2000 7450
2001 7982
2002 8963
2003 9928
2004 10684
2005 12173
2006 13058
2007 13840
2008 15297
2009 16101
2010 18246
2011 20104
2012 21903
2013 23810
2014 26115
2015 28412
2016 28835
2017 29792
2018 30549
2019 31976
2020 35195
2021 36732
2022 31711
2023 30528
2024 36550
2025 39959
2026 427

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562,481 results

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Page 1
Gene therapy.
Brody H. Brody H. Nature. 2018 Dec;564(7735):S5. doi: 10.1038/d41586-018-07639-9. Nature. 2018. PMID: 30542191 No abstract available.
Gene therapy: a double-edged sword with great powers.
Tang R, Xu Z. Tang R, et al. Mol Cell Biochem. 2020 Nov;474(1-2):73-81. doi: 10.1007/s11010-020-03834-3. Epub 2020 Jul 21. Mol Cell Biochem. 2020. PMID: 32696132 Review.
Gene therapy is the treatment of a disease through transferring genetic material into cells of the patients. ...However, concerns about its efficacy and safety have accompanied gene therapy since its birth. In the present manuscript, we first in …
Gene therapy is the treatment of a disease through transferring genetic material into cells of the patients. ...However …
Nonintegrating Gene Therapy Vectors.
Athanasopoulos T, Munye MM, Yáñez-Muñoz RJ. Athanasopoulos T, et al. Hematol Oncol Clin North Am. 2017 Oct;31(5):753-770. doi: 10.1016/j.hoc.2017.06.007. Hematol Oncol Clin North Am. 2017. PMID: 28895845 Free article. Review.
Gene delivery vectors that do not rely on host cell genome integration offer several advantages for gene transfer, chiefly the avoidance of insertional mutagenesis and position effect variegation. ...This article provides an overview of the main nonintegrating viral …
Gene delivery vectors that do not rely on host cell genome integration offer several advantages for gene transfer, chiefly the …
Non-viral Vectors in Gene Therapy: Recent Development, Challenges, and Prospects.
Zu H, Gao D. Zu H, et al. AAPS J. 2021 Jun 2;23(4):78. doi: 10.1208/s12248-021-00608-7. AAPS J. 2021. PMID: 34076797 Free PMC article. Review.
Gene therapy has been experiencing a breakthrough in recent years, targeting various specific cell groups in numerous therapeutic areas. ...Non-viral vectors have been a fast-paced research topic in gene delivery, such as polymers, lipids, inorganic particles …
Gene therapy has been experiencing a breakthrough in recent years, targeting various specific cell groups in numerous therapeu …
Gene Therapy: Towards a New Era of Medicine.
Bhagat M, Kamal R, Sharma J, Kaur K, Sharma A, Singh TG, Bhatia R, Awasthi A. Bhagat M, et al. AAPS PharmSciTech. 2024 Dec 19;26(1):17. doi: 10.1208/s12249-024-03010-6. AAPS PharmSciTech. 2024. PMID: 39702810 Review.
Over the past years, many significant advances have been made in the field of gene therapy and shown promising results in clinical trials conducted. Gene therapy aims at modifying or replacing a defective, inefficient, or nonfunctional gene with …
Over the past years, many significant advances have been made in the field of gene therapy and shown promising results in clin …
A brief history of gene therapy.
Friedmann T. Friedmann T. Nat Genet. 1992 Oct;2(2):93-8. doi: 10.1038/ng1092-93. Nat Genet. 1992. PMID: 1303270 Review.
The concepts of gene therapy arose initially during the 1960s and early 1970s whilst the development of genetically marked cells lines and the clarification of mechanisms of cell transformation by the papaovaviruses polyoma and SV40 was in progress. With the arrival …
The concepts of gene therapy arose initially during the 1960s and early 1970s whilst the development of genetically marked cel …
Entering the Modern Era of Gene Therapy.
Anguela XM, High KA. Anguela XM, et al. Annu Rev Med. 2019 Jan 27;70:273-288. doi: 10.1146/annurev-med-012017-043332. Epub 2018 Nov 26. Annu Rev Med. 2019. PMID: 30477394 Review.
Gene therapies are gaining momentum as promising early successes in clinical studies accumulate and examples of regulatory approval for licensing increase. Investigators are advancing with cautious optimism that effective, durable, and safe therapies will provide benefit t …
Gene therapies are gaining momentum as promising early successes in clinical studies accumulate and examples of regulatory approval f …
Gene Therapy for ALS-A Perspective.
Cappella M, Ciotti C, Cohen-Tannoudji M, Biferi MG. Cappella M, et al. Int J Mol Sci. 2019 Sep 6;20(18):4388. doi: 10.3390/ijms20184388. Int J Mol Sci. 2019. PMID: 31500113 Free PMC article. Review.
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) with no cure. Recent advances in gene therapy open a new perspective to treat this disorder-particularly for the characterized genetic forms. Gene therapy approaches, invo …
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) with no cure. Recent advances in gene therapy open a …
Cochlear Gene Therapy.
Lustig L, Akil O. Lustig L, et al. Cold Spring Harb Perspect Med. 2019 Sep 3;9(9):a033191. doi: 10.1101/cshperspect.a033191. Cold Spring Harb Perspect Med. 2019. PMID: 30323014 Free PMC article. Review.
The past decade has seen significant advances in the understanding of the molecular mechanisms that contribute to hearing, and the environmental and genetic factors that can go awry and lead to hearing loss. This in turn has sparked enormous interest in developing gene …
The past decade has seen significant advances in the understanding of the molecular mechanisms that contribute to hearing, and the environme …
Gene Therapy Now?
Pederson T. Pederson T. FASEB J. 2018 Apr;32(4):1731-1732. doi: 10.1096/fj.180401ufm. FASEB J. 2018. PMID: 29592791 No abstract available.
562,481 results
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