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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 17
1947 4
1948 9
1949 7
1950 12
1951 27
1952 26
1953 23
1954 16
1955 31
1956 32
1957 36
1958 40
1959 49
1960 69
1961 56
1962 54
1963 38
1964 44
1965 49
1966 8
1967 11
1968 29
1969 27
1970 28
1971 59
1972 67
1973 114
1974 96
1975 174
1976 225
1977 168
1978 174
1979 230
1980 220
1981 247
1982 279
1983 304
1984 381
1985 440
1986 441
1987 480
1988 520
1989 790
1990 1065
1991 1243
1992 1624
1993 2511
1994 2663
1995 3474
1996 3908
1997 4556
1998 5246
1999 6155
2000 7451
2001 7982
2002 8959
2003 9927
2004 10684
2005 12170
2006 13058
2007 13838
2008 15296
2009 16100
2010 18246
2011 20105
2012 21889
2013 23811
2014 26116
2015 28410
2016 28841
2017 29801
2018 30563
2019 31986
2020 35201
2021 36611
2022 31599
2023 29913
2024 7613

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497,621 results

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Page 1
Predicting the prognosis of glioma patients with TERT promoter mutations and guiding the specific immune profile of immune checkpoint blockade therapy.
Cao W, Lan J, Hu C, Kong J, Xiang L, Zhang Z, Sun Y, Zeng Z, Lei S. Cao W, et al. Aging (Albany NY). 2024 Mar 18;16. doi: 10.18632/aging.205668. Online ahead of print. Aging (Albany NY). 2024. PMID: 38499392
Data from TCGA were used to identify and validate survival-associated gene signatures, and immune and stromal scores were calculated using the ESTIMATE algorithm. ...TIDE analysis indicated that immune checkpoint blockade (ICB) therapy may benefit glioma patients wi …
Data from TCGA were used to identify and validate survival-associated gene signatures, and immune and stromal scores were calculated …
Disease-specific variant interpretation highlighted the genetic findings in 2325 Japanese patients with retinitis pigmentosa and allied diseases.
Goto K, Koyanagi Y, Akiyama M, Murakami Y, Fukushima M, Fujiwara K, Iijima H, Yamaguchi M, Endo M, Hashimoto K, Ishizu M, Hirakata T, Mizobuchi K, Takayama M, Ota J, Sajiki AF, Kominami T, Ushida H, Fujita K, Kaneko H, Ueno S, Hayashi T, Terao C, Hotta Y, Murakami A, Kuniyoshi K, Kusaka S, Wada Y, Abe T, Nakazawa T, Ikeda Y, Momozawa Y, Sonoda KH, Nishiguchi KM. Goto K, et al. J Med Genet. 2024 Mar 18:jmg-2023-109750. doi: 10.1136/jmg-2023-109750. Online ahead of print. J Med Genet. 2024. PMID: 38499336
BACKGROUND: As gene-specific therapy for inherited retinal dystrophy (IRD) advances, unified variant interpretation across institutes is becoming increasingly important. ...CONCLUSION: A large-scale genetic analysis using the J-IRD-VI guidelines highlighted t …
BACKGROUND: As gene-specific therapy for inherited retinal dystrophy (IRD) advances, unified variant interpretation across ins …
Glanzmann Thrombasthenia 10 Years Later: Progress Made and Future Directions.
Nurden AT, Nurden P. Nurden AT, et al. Semin Thromb Hemost. 2024 Mar 18. doi: 10.1055/s-0044-1782519. Online ahead of print. Semin Thromb Hemost. 2024. PMID: 38499192
The setting up of national networks for IPDs and GT is improving patient care. Hematopoietic stem cell therapy provides a long-term cure for severe cases; however, prophylaxis by monoclonal antibodies designed to accelerate fibrin formation at injured sites in the vasculat …
The setting up of national networks for IPDs and GT is improving patient care. Hematopoietic stem cell therapy provides a long-term c …
Prophylactic Treatment of Children with Hemophilia in Sweden.
Ljung R. Ljung R. Semin Thromb Hemost. 2024 Mar 18. doi: 10.1055/s-0044-1782518. Online ahead of print. Semin Thromb Hemost. 2024. PMID: 38499191
Extended half-life products with half-life increased three to five times have been developed, which can provide superior bleed protection when dosed once-weekly and can maintain therapeutic trough levels when administered less frequently. The ultimate prophylaxis therapy i …
Extended half-life products with half-life increased three to five times have been developed, which can provide superior bleed protection wh …
Epstein-Barr Virus BRLF1 Induces PD-L1 Expression in Nasopharyngeal Carcinoma Cells.
Wu CC, Chen MS, Lee TY, Huang TS, Cho DY, Chen JY. Wu CC, et al. Viral Immunol. 2024 Mar;37(2):115-123. doi: 10.1089/vim.2023.0118. Viral Immunol. 2024. PMID: 38498796
Nasopharyngeal carcinoma (NPC) is a specific human malignancy with unique geographic distribution and genetic backgrounds. Although early treatment with radio-chemotherapy has been proven effective for NPC therapy, its therapeutic efficacy substantially diminishes i …
Nasopharyngeal carcinoma (NPC) is a specific human malignancy with unique geographic distribution and genetic backgrounds. Although e …
Oncolytic vaccinia virus immunotherapy antagonizes image-guided radiotherapy in mouse mammary tumor models.
Umer BA, Noyce RS, Kieser Q, Favis NA, Shenouda MM, Rans KJ, Middleton J, Hitt MM, Evans DH. Umer BA, et al. PLoS One. 2024 Mar 18;19(3):e0298437. doi: 10.1371/journal.pone.0298437. eCollection 2024. PLoS One. 2024. PMID: 38498459
We detected more PD-1 and PD-L1 expression in tumors exposed to IR+VACV but adding an alphaPD-1 antibody to the protocol did not change the way VACV interferes with IG-IR therapy. VACV encodes many immunosuppressive gene products that may interfere with the ability …
We detected more PD-1 and PD-L1 expression in tumors exposed to IR+VACV but adding an alphaPD-1 antibody to the protocol did not change the …
Assessment of treatment outcomes: cytoreductive surgery compared to radiotherapy in oligometastatic prostate cancer - an in-depth quantitative evaluation and retrospective cohort analysis.
Cheng B, He H, Chen B, Zhou Q, Luo T, Li K, Du T, Huang H. Cheng B, et al. Int J Surg. 2024 Mar 18. doi: 10.1097/JS9.0000000000001308. Online ahead of print. Int J Surg. 2024. PMID: 38498388
RESULTS: Five relevant studies' worth of data were included for this meta-analysis, which included 1425 patients with oligometastatic prostate cancer.The outcomes showed that, in comparison to radiation, cytoreductive surgery was linked to a substantially better Cancer Specific S …
RESULTS: Five relevant studies' worth of data were included for this meta-analysis, which included 1425 patients with oligometastatic prosta …
Solid pseudopapillary neoplasm (SPN) of the pancreas: current understanding on its malignant potential and management.
Lu X, Chen H, Zhang T. Lu X, et al. Discov Oncol. 2024 Mar 18;15(1):77. doi: 10.1007/s12672-024-00905-5. Discov Oncol. 2024. PMID: 38498246 Review.
Several confirmed specific pathologic biomarkers are related to its cellular origin, characteristic gene mutation, and cell proliferation. Considering the invasiveness of malignant SPN, it is imperative to enhance the comprehensiveness of its therapy. ...
Several confirmed specific pathologic biomarkers are related to its cellular origin, characteristic gene mutation, and cell prolifera …
Research progress on incomplete partition type 3 inner ear malformation.
Xu K, Xiao Y, Luo J, Chao X, Wang R, Fan Z, Wang H, Xu L. Xu K, et al. Eur Arch Otorhinolaryngol. 2024 Mar 18. doi: 10.1007/s00405-024-08555-7. Online ahead of print. Eur Arch Otorhinolaryngol. 2024. PMID: 38498189 Review.
PURPOSE: This review aims to provides a comprehensive overview of the latest research progress on IP-III inner ear malformation, focusing on its geneticbasis, imaging features, cochlear implantation, and outcome. METHODS: Review the literature on clinical and genetic mecha …
PURPOSE: This review aims to provides a comprehensive overview of the latest research progress on IP-III inner ear malformation, focusing on …
497,621 results
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