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Metabolites of the ellagitannin, geraniin inhibit human ACE; in vitro and in silico evidence.
Looi D, Goh BH, Khan SU, Ahemad N, Palanisamy UD. Looi D, et al. Int J Food Sci Nutr. 2021 Jun;72(4):470-477. doi: 10.1080/09637486.2020.1830263. Epub 2020 Oct 9. Int J Food Sci Nutr. 2021. PMID: 33032478
Among the risk factors of cardiovascular disease, hypertension is the most preventable and treatable, with drugs such as ACE inhibitors. Many ACE inhibitors are known to have undesirable side effects and hence, natural alternatives are being sought. ...It is specula …
Among the risk factors of cardiovascular disease, hypertension is the most preventable and treatable, with drugs such as ACE inhibito …
Antioxidant, anti-semicarbazide-sensitive amine oxidase, and anti-hypertensive activities of geraniin isolated from Phyllanthus urinaria.
Lin SY, Wang CC, Lu YL, Wu WC, Hou WC. Lin SY, et al. Food Chem Toxicol. 2008 Jul;46(7):2485-92. doi: 10.1016/j.fct.2008.04.007. Epub 2008 Apr 13. Food Chem Toxicol. 2008. PMID: 18495318
The inhibitory activities against xanthine oxidase (IC50 were 30.49 microM) were measured. Geraniin also showed dose-dependent inhibitory activities against semicarbazide-sensitive amine oxidase (SSAO, IC50 were 6.58 microM) and against angiotensin converting enzyme (AC …
The inhibitory activities against xanthine oxidase (IC50 were 30.49 microM) were measured. Geraniin also showed dose-dependent inhibi …