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162 results

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Page 1
The potential of GHK as an anti-aging peptide.
Dou Y, Lee A, Zhu L, Morton J, Ladiges W. Dou Y, et al. Aging Pathobiol Ther. 2020 Mar 27;2(1):58-61. doi: 10.31491/apt.2020.03.014. Aging Pathobiol Ther. 2020. PMID: 35083444 Free PMC article.
The molecule has a very high affinity for copper and forms the chelate GHK-Cu. The peptide as well as its Cu (II) chelate have anti-inflammatory and tissue remodeling properties. GHK-Cu has been shown to promote skin remodeling, wound healing and regen …
The molecule has a very high affinity for copper and forms the chelate GHK-Cu. The peptide as well as its Cu (II) chelate have …
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective.
Mortazavi SM, Mohammadi Vadoud SA, Moghimi HR. Mortazavi SM, et al. Bioimpacts. 2024 Apr 28;15:30071. doi: 10.34172/bi.30071. eCollection 2025. Bioimpacts. 2024. PMID: 39963574 Free PMC article. Review.
INTRODUCTION: Peptides are promising and attractive anti-wrinkle active ingredients, amongst which glycyl-histidyl-lysine peptide (GHK) is one of the most broadly promoted peptide for topical application. ...Consequently, GHK has several properties, from woun …
INTRODUCTION: Peptides are promising and attractive anti-wrinkle active ingredients, amongst which glycyl-histidyl-lysine …
Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application.
Dymek M, Olechowska K, Hąc-Wydro K, Sikora E. Dymek M, et al. Pharmaceutics. 2023 Oct 18;15(10):2485. doi: 10.3390/pharmaceutics15102485. Pharmaceutics. 2023. PMID: 37896245 Free PMC article.
They can be used as carriers of both hydrophobic and hydrophilic substances, such as the anti-aging and wound-healing copper-binding peptide, GHK-Cu (glycyl-L-histidyl-L-lysine). Anionic (AL) and cationic (CL) hydrogenated lecithin-based liposomes were obtained as …
They can be used as carriers of both hydrophobic and hydrophilic substances, such as the anti-aging and wound-healing copper-binding peptide …
Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?
Ogórek K, Nowak K, Wadych E, Ruzik L, Timerbaev AR, Matczuk M. Ogórek K, et al. Molecules. 2025 Jan 1;30(1):136. doi: 10.3390/molecules30010136. Molecules. 2025. PMID: 39795193 Free PMC article. Review.
One such CAC that occurs naturally in the human body and displays many beneficial properties (via reducing fine lines and wrinkles, tightening skin, improving its elasticity, etc.) is the glycyl-L-histidyl-L-lysine tripeptide complex of copper (GHK-Cu). GHK- …
One such CAC that occurs naturally in the human body and displays many beneficial properties (via reducing fine lines and wrinkles, tighteni …
Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms.
Mao S, Huang J, Li J, Sun F, Zhang Q, Cheng Q, Zeng W, Lei D, Wang S, Yao J. Mao S, et al. Front Pharmacol. 2025 Jul 2;16:1551843. doi: 10.3389/fphar.2025.1551843. eCollection 2025. Front Pharmacol. 2025. PMID: 40672369 Free PMC article.
In addition to suppressing p-STAT3 expression, GHK-Cu may utilize additional pathways to inhibit inflammatory factors. Furthermore, GHK-Cu may reduce the number of Th17 cells. In summary, GHK-Cu may treat UC by acting on the SIRT1/STAT3 p …
In addition to suppressing p-STAT3 expression, GHK-Cu may utilize additional pathways to inhibit inflammatory factors. Further …
Synergy of GHK-Cu and hyaluronic acid on collagen IV upregulation via fibroblast and ex-vivo skin tests.
Jiang F, Wu Y, Liu Z, Hong M, Huang Y. Jiang F, et al. J Cosmet Dermatol. 2023 Sep;22(9):2598-2604. doi: 10.1111/jocd.15763. Epub 2023 Apr 16. J Cosmet Dermatol. 2023. PMID: 37062921
INTRODUCTION: GHK-Cu and HA are two commonly used skin care ingredients, both of which were reported to enhance collagen synthesis. ...CONCLUSION: The co-effect of GHK-Cu and HA was revealed. Their synergy brings an insight to anti-aging technology: ch …
INTRODUCTION: GHK-Cu and HA are two commonly used skin care ingredients, both of which were reported to enhance collagen synth …
GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis.
Wang X, Liu B, Xu Q, Sun H, Shi M, Wang D, Guo M, Yu J, Zhao C, Feng B. Wang X, et al. Wound Repair Regen. 2017 Apr;25(2):270-278. doi: 10.1111/wrr.12520. Epub 2017 Apr 27. Wound Repair Regen. 2017. PMID: 28370978
The nanoscaled GHK-Cu-liposomes promoted HUVECs proliferation, with a 33.1% increased rate. Flow cytometry analysis showed increased cell number at G1 stage and decreased cell number at G2 stage after GHK-Cu-liposomes treatment. ...In a mice scald mode …
The nanoscaled GHK-Cu-liposomes promoted HUVECs proliferation, with a 33.1% increased rate. Flow cytometry analysis showed inc …
162 results