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138 results

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Page 1
Ginsenosides for the treatment of metabolic syndrome and cardiovascular diseases: Pharmacology and mechanisms.
Fan W, Huang Y, Zheng H, Li S, Li Z, Yuan L, Cheng X, He C, Sun J. Fan W, et al. Biomed Pharmacother. 2020 Dec;132:110915. doi: 10.1016/j.biopha.2020.110915. Epub 2020 Nov 2. Biomed Pharmacother. 2020. PMID: 33254433 Free article. Review.
Epidemiological studies showed that the metabolic syndromes (MetS) and cardiovascular diseases (CVDs) are responsible for a serious threat to human health worldwide. MetS is a syndromes characterized by fat metabolism disorder, obesity, diabetes, insulin resistance and oth …
Epidemiological studies showed that the metabolic syndromes (MetS) and cardiovascular diseases (CVDs) are responsible for a serious threat t …
Ginsenoside Rg1 Alleviates Ulcerative Colitis in Obese Mice by Regulating the Gut Microbiota-Lipid Metabolism-Th1/Th2/Th17 Cells Axis.
Zhong Y, Xiao Q, Huang J, Yu S, Chen L, Wan Q, Zhang Z, Luo L, Song L, Zhao H, Zhou W, Liu D. Zhong Y, et al. J Agric Food Chem. 2023 Dec 20;71(50):20073-20091. doi: 10.1021/acs.jafc.3c04811. Epub 2023 Dec 8. J Agric Food Chem. 2023. PMID: 38064669
Ginsenoside Rg1 (G-Rg1) has various pharmacological properties including antiobesity, immunomodulatory, and anti-inflammatory effects. ...
Ginsenoside Rg1 (G-Rg1) has various pharmacological properties including antiobesity, immunomodulatory, and anti-inflammatory …
Effects of Dietary Ginsenoside Rg1 Supplementation on Growth Performance, Gut Health, and Serum Immunity in Broiler Chickens.
Song Z, Xie K, Zhang Y, Xie Q, He X, Zhang H. Song Z, et al. Front Nutr. 2021 Nov 29;8:705279. doi: 10.3389/fnut.2021.705279. eCollection 2021. Front Nutr. 2021. PMID: 34912836 Free PMC article.
The restriction and banning of antibiotics in farm animal feed has led to a search for promising substitutes for antibiotics to promote growth and maintain health for livestock and poultry. Ginsenoside Rg1, which is one of the most effective bioactive compone …
The restriction and banning of antibiotics in farm animal feed has led to a search for promising substitutes for antibiotics to promote grow …
Ginsenoside Rg1 reduces cardiac inflammation against myocardial ischemia/reperfusion injury by inhibiting macrophage polarization.
Xu X, Wu Q, Pei K, Zhang M, Mao C, Zhong X, Huang Y, Dai Y, Yin R, Chen Z, Wang X. Xu X, et al. J Ginseng Res. 2024 Nov;48(6):570-580. doi: 10.1016/j.jgr.2024.07.003. Epub 2024 Jul 21. J Ginseng Res. 2024. PMID: 39583164 Free PMC article.
BACKGROUND: Myocardial ischemia/reperfusion (MI/R) injury is the main cause of death worldwide and poses a significant threat to cardiac health. Ginsenoside Rg1 has been shown to have inhibitory effects on inflammatory activation, oxidative stress, and cardia …
BACKGROUND: Myocardial ischemia/reperfusion (MI/R) injury is the main cause of death worldwide and poses a significant threat to cardiac …
Ginsenoside Rg1 modulates PI3K/AKT pathway for enhanced osteogenesis via GPER.
Jiang Z, Deng L, Li M, Alonge E, Wang Y, Wang Y. Jiang Z, et al. Phytomedicine. 2024 Feb;124:155284. doi: 10.1016/j.phymed.2023.155284. Epub 2023 Dec 17. Phytomedicine. 2024. PMID: 38176267
BACKGROUND: Osteoporosis is a systemic skeletal disorder characterized by decreased bone density and the degradation of bone tissue microarchitecture. Ginsenoside Rg1, derived from Panax ginseng, has been a part of traditional Chinese medicine in China for centuries …
BACKGROUND: Osteoporosis is a systemic skeletal disorder characterized by decreased bone density and the degradation of bone tissue microarc …
Ginsenoside Rg1 treats ischemic stroke by regulating CKLF1/CCR5 axis-induced neuronal cell pyroptosis.
Long J, Sun Y, Liu S, Chen C, Yan Q, Lin Y, Zhang Z, Chu S, Yang Y, Yang S, Lin M, Liu X, Liang J, Chen N, Ai Q. Long J, et al. Phytomedicine. 2024 Jan;123:155238. doi: 10.1016/j.phymed.2023.155238. Epub 2023 Nov 24. Phytomedicine. 2024. PMID: 38128394
Thus, there is a crucial need to explore novel therapeutic agents for ischemic stroke. Ginsenoside Rg1 (Rg1), a potential neuroprotective agent, exhibits anti-ischemic effects attributed to its anti-inflammatory, anti-oxidant, and anti-apoptotic properties. ...
Thus, there is a crucial need to explore novel therapeutic agents for ischemic stroke. Ginsenoside Rg1 (Rg1), a potential neur …
Ginsenoside Rg1: A Neuroprotective Natural Dammarane-Type Triterpenoid Saponin With Anti-Depressive Properties.
Han D, Zhao Z, Mao T, Gao M, Yang X, Gao Y. Han D, et al. CNS Neurosci Ther. 2024 Dec;30(12):e70150. doi: 10.1111/cns.70150. CNS Neurosci Ther. 2024. PMID: 39639753 Free PMC article. Review.
MATERIALS AND METHODS: We evaluated preclinical studies to comprehensively discuss the antidepressant mechanism of ginsenoside Rg1 and review its toxicity and medicinal value. Additionally, pharmacological network and molecular docking analyses were performed to fur …
MATERIALS AND METHODS: We evaluated preclinical studies to comprehensively discuss the antidepressant mechanism of ginsenoside Rg1 …
Hepataprotective effects of ginsenoside Rg1 - A review.
Gao Y, Chu S, Zhang Z, Chen N. Gao Y, et al. J Ethnopharmacol. 2017 Jul 12;206:178-183. doi: 10.1016/j.jep.2017.04.012. Epub 2017 Apr 17. J Ethnopharmacol. 2017. PMID: 28427912 Review.
Ginseng saponins, also known as ginsenosides, are principal constituents and have been treated to be responsible for disparate ginseng health benefits. The current review mainly focuses on ginsenoside Rg1, a compound isolated from traditional Chinese herbal m …
Ginseng saponins, also known as ginsenosides, are principal constituents and have been treated to be responsible for disparate ginseng he …
Ginsenoside-Rg1 mitigates cardiac arrest-induced cognitive damage by modulating neuroinflammation and hippocampal plasticity.
Wu Z, Huang J, Bai X, Wang Q, Wang F, Xu J, Tang H, Yin C, Wang Y, Yu F, Zhang H. Wu Z, et al. Eur J Pharmacol. 2023 Jan 5;938:175431. doi: 10.1016/j.ejphar.2022.175431. Epub 2022 Dec 1. Eur J Pharmacol. 2023. PMID: 36463944 Free article.
Ginsenoside-Rg1 can effectively ameliorate mental disorders, but whether ginsenoside-Rg1 plays a neuroprotective role in cardiac arrest and cardiopulmonary resuscitation (CA/CPR)-induced cognitive impairment remains unclear. ...In addition, ginsenos …
Ginsenoside-Rg1 can effectively ameliorate mental disorders, but whether ginsenoside-Rg1 plays a neuroprotective …
Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury through inhibiting the inflammatory activation of microglia.
Guan Y, Cao YL, Liu JW, Liu LT, Zheng YJ, Ma XF, Zhai FG. Guan Y, et al. Exp Cell Res. 2023 May 1;426(1):113552. doi: 10.1016/j.yexcr.2023.113552. Epub 2023 Mar 11. Exp Cell Res. 2023. PMID: 36914061
Our previous studies have shown that ginsenoside Rg1 had a significant protective effect on focal cerebral I/R injury in middle cerebral artery occlusion (MCAO) rats. ...The mechanism study showed that the effect of ginsenoside Rg1 depends on the suppr …
Our previous studies have shown that ginsenoside Rg1 had a significant protective effect on focal cerebral I/R injury in middl …
138 results