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5,550 results

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Page 1
Ginsenosides Rg1, Rb1 and rare ginsenosides: Promising candidate agents for Parkinson's disease and Alzheimer's disease and network pharmacology analysis.
Jiang M, Chi J, Qiao Y, Wang J, Zhang Z, Liu J, Sheng X, Yuan L. Jiang M, et al. Pharmacol Res. 2025 Feb;212:107578. doi: 10.1016/j.phrs.2025.107578. Epub 2025 Jan 3. Pharmacol Res. 2025. PMID: 39756554 Free article.
In particular, we used network pharmacology to identify the potential targets of ginsenosides Rg1 and Rb1 in PD and AD. By analysing the existing research advances and network pharmacology results, we found that the neuroprotective effects of ginsenosides
In particular, we used network pharmacology to identify the potential targets of ginsenosides Rg1 and Rb1 in PD and AD. By ana …
Mechanism of Ginsenosides in the Treatment of Diabetes Mellitus Based on Network Pharmacology and Molecular Docking.
Huang S, Li F, Xue D, Shi X, Fang X, Li J, Fu Y, Zhao Y, Jin D. Huang S, et al. Int J Mol Sci. 2025 May 30;26(11):5300. doi: 10.3390/ijms26115300. Int J Mol Sci. 2025. PMID: 40508108 Free PMC article.
Unlike previous studies focusing solely on crude extracts or individual ginsenosides, this study integrates network pharmacology, molecular docking, and molecular dynamics (MD) simulations to systematically elucidate the multi-target mechanisms of ginsenosides
Unlike previous studies focusing solely on crude extracts or individual ginsenosides, this study integrates network pharmacology
Pharmacological mechanisms and drug delivery systems of ginsenoside Rg3: A comprehensive review.
Yao ZW, Zhu H. Yao ZW, et al. Pharmacol Res. 2025 Jun;216:107799. doi: 10.1016/j.phrs.2025.107799. Epub 2025 May 23. Pharmacol Res. 2025. PMID: 40414584 Free article. Review.
Ginsenoside Rg3, as one of the major active components of Panax ginseng, exhibits significant anti-tumor, anti-inflammatory, antioxidant, antidiabetic, hepatoprotective, wound healing and immunomodulatory pharmacological effects and has been developed as an adjuvant therap
Ginsenoside Rg3, as one of the major active components of Panax ginseng, exhibits significant anti-tumor, anti-inflammatory, antioxid
Imeglimin: A Clinical Pharmacology Review.
Chevalier C, Fouqueray P, Bolze S. Chevalier C, et al. Clin Pharmacokinet. 2023 Oct;62(10):1393-1411. doi: 10.1007/s40262-023-01301-y. Epub 2023 Sep 15. Clin Pharmacokinet. 2023. PMID: 37713097 Review.
Integration of network pharmacology and proteomics analysis to identify key target pathways of Ginsenoside Re for myocardial ischemia.
Cai J, Zhan Y, Huang K, Han S, Lin Z, Chen R, Luo Q, Li Z, Chen B, Li S. Cai J, et al. Phytomedicine. 2024 Sep;132:155728. doi: 10.1016/j.phymed.2024.155728. Epub 2024 May 10. Phytomedicine. 2024. PMID: 38853122
BACKGROUND: Clinically, various diseases cause myocardial ischemia (MI), which further induces severe cardiac injury and leads to high mortality in patients. Ginsenoside Re, one of the major ginsenosides in ginseng, can regulate the level of oxidative stress in the …
BACKGROUND: Clinically, various diseases cause myocardial ischemia (MI), which further induces severe cardiac injury and leads to high morta …
Ginsenosides in cancer: Proliferation, metastasis, and drug resistance.
Yang Y, Nan Y, Du Y, Liu W, Ning N, Chen G, Gu Q, Yuan L. Yang Y, et al. Biomed Pharmacother. 2024 Aug;177:117049. doi: 10.1016/j.biopha.2024.117049. Epub 2024 Jun 29. Biomed Pharmacother. 2024. PMID: 38945081 Free article. Review.
Mey., is widely used in Chinese herbal medicine. Ginsenosides, the primary active components of ginseng, exhibit diverse anticancer functions through various mechanisms, such as inhibiting tumor cell proliferation, promoting apoptosis, and suppressing cell invasion and mig …
Mey., is widely used in Chinese herbal medicine. Ginsenosides, the primary active components of ginseng, exhibit diverse anticancer f …
Ginsenoside Rg1: A Neuroprotective Natural Dammarane-Type Triterpenoid Saponin With Anti-Depressive Properties.
Han D, Zhao Z, Mao T, Gao M, Yang X, Gao Y. Han D, et al. CNS Neurosci Ther. 2024 Dec;30(12):e70150. doi: 10.1111/cns.70150. CNS Neurosci Ther. 2024. PMID: 39639753 Free PMC article. Review.
Currently, single-target antidepressants typically alleviate depressive symptoms or delay the progression of depression rather than cure it. Ginsenoside Rg1 is one of the main ginsenosides found in Panax ginseng roots. It improves depressive symptoms through various …
Currently, single-target antidepressants typically alleviate depressive symptoms or delay the progression of depression rather than cure it. …
Ginsenosides in vascular remodeling: Cellular and molecular mechanisms of their therapeutic action.
Zhu GX, Zuo JL, Xu L, Li SQ. Zhu GX, et al. Pharmacol Res. 2021 Jul;169:105647. doi: 10.1016/j.phrs.2021.105647. Epub 2021 May 6. Pharmacol Res. 2021. PMID: 33964471 Review.
This review is intended to discuss the therapeutic effects and mechanisms of ginsenosides in some diseases involved in VR. Besides, we herein also give a new and contradictory insight into intracellular and molecular signaling of ginsenosides in all kinds of vascula …
This review is intended to discuss the therapeutic effects and mechanisms of ginsenosides in some diseases involved in VR. Besides, w …
Anti-Angiogenic Properties of Ginsenoside Rg3.
Nakhjavani M, Smith E, Townsend AR, Price TJ, Hardingham JE. Nakhjavani M, et al. Molecules. 2020 Oct 23;25(21):4905. doi: 10.3390/molecules25214905. Molecules. 2020. PMID: 33113992 Free PMC article. Review.
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3). ...
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosi
Insights into the antitumor mechanism of ginsenosides Rg3.
Liu Z, Liu T, Li W, Li J, Wang C, Zhang K. Liu Z, et al. Mol Biol Rep. 2021 Mar;48(3):2639-2652. doi: 10.1007/s11033-021-06187-2. Epub 2021 Mar 4. Mol Biol Rep. 2021. PMID: 33661439 Review.
Panax ginseng, an ancient herb, belonging to Chinese traditional medicine, is an important herb that has a remarkable impact on various diseases. Ginsenoside Rg3, one of the most abundant ginsenosides, exerts significant functions in the prevention of various types …
Panax ginseng, an ancient herb, belonging to Chinese traditional medicine, is an important herb that has a remarkable impact on various dise …
5,550 results