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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1956 1
1957 4
1958 2
1959 4
1960 2
1961 1
1962 2
1963 1
1964 2
1965 2
1966 2
1968 1
1970 3
1971 2
1972 2
1975 2
1976 7
1977 3
1978 3
1979 3
1980 5
1981 6
1982 11
1983 8
1984 13
1985 19
1986 16
1987 13
1988 18
1989 25
1990 38
1991 32
1992 62
1993 54
1994 80
1995 75
1996 70
1997 65
1998 84
1999 69
2000 99
2001 105
2002 99
2003 89
2004 79
2005 105
2006 115
2007 119
2008 124
2009 104
2010 96
2011 98
2012 110
2013 95
2014 109
2015 95
2016 96
2017 73
2018 79
2019 77
2020 87
2021 87
2022 76
2023 62
2024 85
2025 79
2026 42

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Search Results

3,026 results

Results by year

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Page 1
Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury.
Lai K, Pritišanac I, Liu ZQ, Liu HW, Gong LN, Li MX, Lu JF, Qi X, Xu TL, Forman-Kay J, Shi HB, Wang LY, Yin SK. Lai K, et al. Nature. 2024 Jul;631(8022):826-834. doi: 10.1038/s41586-024-07684-7. Epub 2024 Jul 10. Nature. 2024. PMID: 38987597 Free PMC article.
Here we show that glutamate and its structural analogues, including NMDAR antagonist L-AP5 (also known as APV), robustly potentiate currents mediated by acid-sensing ion channels (ASICs) associated with acidosis-induced neurotoxicity in stroke(4). ...
Here we show that glutamate and its structural analogues, including NMDAR antagonist L-AP5 (also known as APV), robustly potentiate currents …
Bradykinin formation by mutant plasminogen.
Kaplan AP. Kaplan AP. Blood. 2022 May 5;139(18):2732-2733. doi: 10.1182/blood.2022015610. Blood. 2022. PMID: 35511189 Free article. No abstract available.
Manipulation of Glutamatergic Neuronal Activity in the Primary Motor Cortex Regulates Cardiac Function in Normal and Myocardial Infarction Mice.
Bo W, Cai M, Ma Y, Di L, Geng Y, Li H, Tang C, Tai F, He Z, Tian Z. Bo W, et al. Adv Sci (Weinh). 2024 May;11(20):e2305581. doi: 10.1002/advs.202305581. Epub 2024 Mar 15. Adv Sci (Weinh). 2024. PMID: 38488323 Free PMC article.
They also help the understanding of the neural mechanisms underlying cardiovascular regulation....
They also help the understanding of the neural mechanisms underlying cardiovascular regulation....
Dietary glutamic acid and aspartic acid as biomarkers for predicting diabetic retinopathy.
Park SY, Kim J, Son JI, Rhee SY, Kim DY, Chon S, Lim H, Woo JT. Park SY, et al. Sci Rep. 2021 Mar 31;11(1):7244. doi: 10.1038/s41598-021-83165-5. Sci Rep. 2021. PMID: 33790305 Free PMC article.
The 2067 patients with type 2 diabetes without DR were included. The baseline intakes of energy, glutamic acid and aspartic acid were assessed using a 3-day food records. The risk of DR incidence based on intake of glutamic acid and aspartic …
The 2067 patients with type 2 diabetes without DR were included. The baseline intakes of energy, glutamic acid and aspartic …
Low-frequency variants in genes involved in glutamic acid metabolism and gamma-glutamyl cycle and risk of coronary artery disease in type 2 diabetes.
Giuffrida FMA, Rai SK, Tang Y, Mendonça C, Frodsham SG, Shah HS, Pezzolesi MG, Sun Q, Doria A. Giuffrida FMA, et al. Cardiovasc Diabetol. 2024 Nov 13;23(1):406. doi: 10.1186/s12933-024-02442-5. Cardiovasc Diabetol. 2024. PMID: 39538235 Free PMC article.
BACKGROUND: A common genetic variant at the glutamate-ammonia ligase (GLUL) locus has been previously associated with an increased risk of coronary artery disease (CAD) as well as alterations of glutamic acid metabolism and the gamma-glutamyl cycle in individ …
BACKGROUND: A common genetic variant at the glutamate-ammonia ligase (GLUL) locus has been previously associated with an increased risk of c …
Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes.
Qi L, Qi Q, Prudente S, Mendonca C, Andreozzi F, di Pietro N, Sturma M, Novelli V, Mannino GC, Formoso G, Gervino EV, Hauser TH, Muehlschlegel JD, Niewczas MA, Krolewski AS, Biolo G, Pandolfi A, Rimm E, Sesti G, Trischitta V, Hu F, Doria A. Qi L, et al. JAMA. 2013 Aug 28;310(8):821-8. doi: 10.1001/jama.2013.276305. JAMA. 2013. PMID: 23982368 Free PMC article.
IMPORTANCE: Diabetes is associated with an elevated risk of coronary heart disease (CHD). Previous studies have suggested that the genetic factors predisposing to excess cardiovascular risk may be different in diabetic and nondiabetic individuals. ...A decreased rat …
IMPORTANCE: Diabetes is associated with an elevated risk of coronary heart disease (CHD). Previous studies have suggested that the ge …
Stroke.
Choi D. Choi D. Neurobiol Dis. 2000 Oct;7(5):552-8. doi: 10.1006/nbdi.2000.0354. Neurobiol Dis. 2000. PMID: 11042076 No abstract available.
Delayed neuronal death.
Kirino T. Kirino T. Neuropathology. 2000 Sep;20 Suppl:S95-7. doi: 10.1046/j.1440-1789.2000.00306.x. Neuropathology. 2000. PMID: 11037198 Review.
Stroke therapy.
Zivin JA, Choi DW. Zivin JA, et al. Sci Am. 1991 Jul;265(1):56-63. doi: 10.1038/scientificamerican0791-56. Sci Am. 1991. PMID: 1679258 Clinical Trial. No abstract available.
GLS2 links glutamine metabolism and atherosclerosis by remodeling artery walls.
Murcy F, Borowczyk C, Gourion-Arsiquaud S, Torrino S, Ouahrouche N, Barouillet T, Dussaud S, Couralet M, Vaillant N, Merlin J, Berquand A, Kaikkonen MU, McClelland RL, Tressel W, Stein J, Thorp EB, Bertero T, Barbry P, Bailly-Maitre B, Gautier EL, Karjalainen MK, Kettunen J, Duca L, Shea S, Yvan-Charvet L. Murcy F, et al. Nat Cardiovasc Res. 2024 Dec;3(12):1454-1467. doi: 10.1038/s44161-024-00566-1. Epub 2024 Nov 19. Nat Cardiovasc Res. 2024. PMID: 39562782
Metabolic dysregulation, including perturbed glutamine-glutamate homeostasis, is common among patients with cardiovascular diseases, but the underlying mechanisms remain largely unknown. Using the human MESA cohort, here we show that plasma glutamine-glutamate ratio …
Metabolic dysregulation, including perturbed glutamine-glutamate homeostasis, is common among patients with cardiovascular disease …
3,026 results