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Year Number of Results
1982 1
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1,072 results

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Page 1
Amyotrophic Lateral Sclerosis: Pathophysiological Mechanisms and Treatment Strategies (Part 2).
Tolochko C, Shiryaeva O, Alekseeva T, Dyachuk V. Tolochko C, et al. Int J Mol Sci. 2025 May 29;26(11):5240. doi: 10.3390/ijms26115240. Int J Mol Sci. 2025. PMID: 40508048 Free PMC article. Review.
Over the past decade, understanding of the key pathogenetic links of ALS, including glutamate-mediated excitotoxicity and oxidative stress, has significantly advanced. This review considers the recent evidence on molecular mechanisms of these processes, as well as t …
Over the past decade, understanding of the key pathogenetic links of ALS, including glutamate-mediated excitotoxicity and oxidative …
Cancer metabolism: a therapeutic perspective.
Martinez-Outschoorn UE, Peiris-Pagés M, Pestell RG, Sotgia F, Lisanti MP. Martinez-Outschoorn UE, et al. Nat Rev Clin Oncol. 2017 Jan;14(1):11-31. doi: 10.1038/nrclinonc.2016.60. Epub 2016 May 4. Nat Rev Clin Oncol. 2017. PMID: 27141887 Review.
Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage.
Sun ZW, Zhang L, Zhu SJ, Chen WC, Mei B. Sun ZW, et al. Neurosci Bull. 2010 Feb;26(1):8-16. doi: 10.1007/s12264-010-0813-7. Neurosci Bull. 2010. PMID: 20101268 Free PMC article.
The cytosolic calcium concentration was tested by calcium influx assay. The glutamate-induced oxidative stress was analyzed by cytosolic glutathione assay, superoxide dismutase (SOD) assay and extracellular malondialdehyde (MDA) assay. ...CONCLUSION: Glutamate exert …
The cytosolic calcium concentration was tested by calcium influx assay. The glutamate-induced oxidative stress was analyzed by …
L-glutamic acid modulates antioxidant defense systems and nutrient homeostasis in lentil (Lens culinaris Medik.) under copper toxicity.
Fardus J, Hossain S, Rob MM, Fujita M. Fardus J, et al. Environ Sci Pollut Res Int. 2023 Jul;30(32):78507-78520. doi: 10.1007/s11356-023-27993-0. Epub 2023 Jun 4. Environ Sci Pollut Res Int. 2023. PMID: 37270757
Copper (Cu), an essential micronutrient, can generate reactive oxygen species (ROS) at its supra-optimal level in living cells as a transition metal, thus producing oxidative stress in plants. Therefore, protecting plants from Cu-induced oxidative stress …
Copper (Cu), an essential micronutrient, can generate reactive oxygen species (ROS) at its supra-optimal level in living cells as a transiti …
Antioxidant and gastrointestinal cytoprotective effect of edible polypeptide poly-gamma-glutamic acid.
Lee JM, Jang WJ, Park SH, Kong IS. Lee JM, et al. Int J Biol Macromol. 2020 Jun 15;153:616-624. doi: 10.1016/j.ijbiomac.2020.03.050. Epub 2020 Mar 9. Int J Biol Macromol. 2020. PMID: 32165198
The antioxidant effects and cytoprotection of the poly-gamma-glutamic acid (gamma-PGA) were investigated. gamma-PGA with a molecular weight of ~400 kDa showed hydroxyl radical (OH( )) averting capacity (HORAC), 85.2% at 1 mg/mL, which was caused by the chelat …
The antioxidant effects and cytoprotection of the poly-gamma-glutamic acid (gamma-PGA) were investigated. gamma-PGA wit …
Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats.
Salyha N, Salyha Y. Salyha N, et al. Environ Toxicol Pharmacol. 2018 Dec;64:155-163. doi: 10.1016/j.etap.2018.10.010. Epub 2018 Nov 2. Environ Toxicol Pharmacol. 2018. PMID: 30412861
Exposure to the organophosphorus insecticide chlorpyrifos (CPF) can lead to oxidative stress. The aim of this work was to investigate and compare the protective effects of amino acids (l-glutamic acid (l-Glu) and l-cysteine (L-Cys) alone or in combinat …
Exposure to the organophosphorus insecticide chlorpyrifos (CPF) can lead to oxidative stress. The aim of this work was to inve …
l-glycine and l-glutamic acid protect Pediococcus pentosaceus R1 against oxidative damage induced by hydrogen peroxide.
Zhang H, Wang Z, Li Z, Wang K, Kong B, Chen Q. Zhang H, et al. Food Microbiol. 2022 Feb;101:103897. doi: 10.1016/j.fm.2021.103897. Epub 2021 Sep 3. Food Microbiol. 2022. PMID: 34579850
The effects of l-glycine (Gly) and l-glutamic acid (Glu) on oxidative damage induced by hydrogen peroxide (H(2)O(2)) in Pediococcus pentosaceus R1 were investigated. ...Gly and Glu significantly enhance the activities of superoxide dismutase and glutathione p …
The effects of l-glycine (Gly) and l-glutamic acid (Glu) on oxidative damage induced by hydrogen peroxide (H(2)O(2)) in …
Hydrogen sulfide releasing poly(gamma-glutamic acid) biocomposite hydrogel with monitoring, antioxidant, and antibacterial properties for diabetic wound healing.
Liu X, Han X, Shang Y, Wang L, Shen J, Yuan J. Liu X, et al. Int J Biol Macromol. 2023 Dec 31;253(Pt 6):127053. doi: 10.1016/j.ijbiomac.2023.127053. Epub 2023 Sep 28. Int J Biol Macromol. 2023. PMID: 37774813
Adverse factors such as high levels of glucose, oxidative stress, inflammation, and bacterial infection impede diabetic wound healing and even worsen wounds. ...In this work, a multifunctional poly(gamma-glutamic acid)(PGA) hydrogel encapsulated with k …
Adverse factors such as high levels of glucose, oxidative stress, inflammation, and bacterial infection impede diabetic wound …
Involvement of Oxidative Stress and Nutrition in the Anatomy of Orofacial Pain.
Gianò M, Franco C, Castrezzati S, Rezzani R. Gianò M, et al. Int J Mol Sci. 2023 Aug 23;24(17):13128. doi: 10.3390/ijms241713128. Int J Mol Sci. 2023. PMID: 37685933 Free PMC article. Review.
Moreover, we describe the important role of oxidative stress and its association with inflammation in the etiogenesis and modulation of pain in orofacial regions. We also explore the warning and protective function of orofacial pain and the possible action of ant …
Moreover, we describe the important role of oxidative stress and its association with inflammation in the etiogenesis and modu …
Application of glutamic acid improved As tolerance in aromatic rice at early growth stage.
Huang S, Yang X, Chen G, Wang X. Huang S, et al. Chemosphere. 2023 May;322:138173. doi: 10.1016/j.chemosphere.2023.138173. Epub 2023 Feb 18. Chemosphere. 2023. PMID: 36806810
To alleviate the arsenic (As) toxicity in aromatic rice, a hydroponic experiment of two As concentrations (0 and 100 muM sodium arsenite: A0, A1), three glutamic acid (Glu) concentrations (0, 100, and 500 muM l-glutamic acid: G0, G1, and G2) with Xiang …
To alleviate the arsenic (As) toxicity in aromatic rice, a hydroponic experiment of two As concentrations (0 and 100 muM sodium arsenite: A0 …
1,072 results