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Year Number of Results
1932 2
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1935 3
1936 2
1939 4
1940 1
1941 1
1943 4
1944 1
1945 5
1946 9
1947 17
1948 16
1949 18
1950 14
1951 12
1952 11
1953 21
1954 27
1955 21
1956 32
1957 32
1958 31
1959 20
1960 22
1961 23
1962 48
1963 93
1964 145
1965 120
1966 130
1967 146
1968 194
1969 217
1970 258
1971 285
1972 344
1973 319
1974 352
1975 389
1976 375
1977 370
1978 354
1979 367
1980 418
1981 420
1982 479
1983 474
1984 506
1985 613
1986 576
1987 594
1988 627
1989 744
1990 908
1991 866
1992 894
1993 951
1994 1056
1995 1033
1996 1045
1997 1101
1998 1090
1999 1118
2000 1147
2001 1086
2002 1070
2003 1094
2004 1152
2005 1191
2006 1279
2007 1304
2008 1301
2009 1298
2010 1364
2011 1553
2012 1591
2013 1750
2014 1694
2015 1682
2016 1883
2017 1772
2018 1892
2019 1833
2020 2011
2021 2161
2022 2220
2023 2067
2024 2139
2025 1279

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56,481 results

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Page 1
Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation.
Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P. Cruzat V, et al. Nutrients. 2018 Oct 23;10(11):1564. doi: 10.3390/nu10111564. Nutrients. 2018. PMID: 30360490 Free PMC article. Review.
Glutamine is the most abundant and versatile amino acid in the body. In health and disease, the rate of glutamine consumption by immune cells is similar or greater than glucose. ...Therefore, this paper provides an integrated review of how glutamine metabolis …
Glutamine is the most abundant and versatile amino acid in the body. In health and disease, the rate of glutamine consumption …
Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition.
Coqueiro AY, Rogero MM, Tirapegui J. Coqueiro AY, et al. Nutrients. 2019 Apr 17;11(4):863. doi: 10.3390/nu11040863. Nutrients. 2019. PMID: 30999561 Free PMC article. Review.
Glutamine is a conditionally essential amino acid widely used in sports nutrition, especially because of its immunomodulatory role. ...Thus, despite improving some fatigue parameters, glutamine supplementation seems to have limited effects on performance....
Glutamine is a conditionally essential amino acid widely used in sports nutrition, especially because of its immunomodulatory role. . …
The effect of glutamine supplementation on athletic performance, body composition, and immune function: A systematic review and a meta-analysis of clinical trials.
Ramezani Ahmadi A, Rayyani E, Bahreini M, Mansoori A. Ramezani Ahmadi A, et al. Clin Nutr. 2019 Jun;38(3):1076-1091. doi: 10.1016/j.clnu.2018.05.001. Epub 2018 May 9. Clin Nutr. 2019. PMID: 29784526
There was no association between glutamine ingestion and other outcomes investigated. CONCLUSION: According to this meta-analysis, generally, glutamine supplementation has no effect on athletics immune system, aerobic performance, and body composition. However, the …
There was no association between glutamine ingestion and other outcomes investigated. CONCLUSION: According to this meta-analysis, ge …
Dosing and efficacy of glutamine supplementation in human exercise and sport training.
Gleeson M. Gleeson M. J Nutr. 2008 Oct;138(10):2045S-2049S. doi: 10.1093/jn/138.10.2045S. J Nutr. 2008. PMID: 18806122 Free article. Review.
However, several recent glutamine feeding intervention studies indicate that although the plasma glutamine concentration can be kept constant during and after prolonged strenuous exercise, the glutamine supplementation does not prevent the postexercise change …
However, several recent glutamine feeding intervention studies indicate that although the plasma glutamine concentration can b …
A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries.
Heyland DK, Wibbenmeyer L, Pollack J, Friedman B, Turgeon AF, Eshraghi N, Jeschke MG, Bélisle S, Grau D, Mandell S, Velamuri SR, Hundeshagen G, Moiemen N, Shokrollahi K, Foster K, Huss F, Collins D, Savetamal A, Gurney JM, Depetris N, Stoppe C, Ortiz-Reyes L, Garrel D, Day AG; RE-ENERGIZE Trial Team. Heyland DK, et al. N Engl J Med. 2022 Sep 15;387(11):1001-1010. doi: 10.1056/NEJMoa2203364. Epub 2022 Sep 9. N Engl J Med. 2022. PMID: 36082909 Free article. Clinical Trial.
BACKGROUND: Glutamine is thought to have beneficial effects on the metabolic and stress response to severe injury. ...Mortality at 6 months was 17.2% in the glutamine group and 16.2% in the placebo group (hazard ratio for death, 1.06; 95% CI, 0.80 to 1.41). ...
BACKGROUND: Glutamine is thought to have beneficial effects on the metabolic and stress response to severe injury. ...Mortality at 6 …
Glutamine.
Labow BI, Souba WW. Labow BI, et al. World J Surg. 2000 Dec;24(12):1503-13. doi: 10.1007/s002680010269. World J Surg. 2000. PMID: 11193715 Review.
Relatively little was known about glutamine metabolism until the 1930s, when Sir Hans Krebs first demonstrated glutamine hydrolysis and biosynthesis in the kidney. ...In contrast to this usual dietary availability, studies in stressed patients indicate that consider …
Relatively little was known about glutamine metabolism until the 1930s, when Sir Hans Krebs first demonstrated glutamine hydro …
Targeting Glutamine Metabolism as an Attractive Therapeutic Strategy for Acute Myeloid Leukemia.
Xiao Y, Hu B, Guo Y, Zhang D, Zhao Y, Chen Y, Li N, Yu L. Xiao Y, et al. Curr Treat Options Oncol. 2023 Aug;24(8):1021-1035. doi: 10.1007/s11864-023-01104-0. Epub 2023 May 30. Curr Treat Options Oncol. 2023. PMID: 37249801 Free PMC article. Review.
Glutamine-target strategies including depletion of systemic glutamine and application of glutamine uptake inhibitors, glutamine antagonists/analogues, and glutaminase inhibitors. Because glutamine metabolism involved in multiple pathways in cell …
Glutamine-target strategies including depletion of systemic glutamine and application of glutamine uptake inhibitors, …
L-glutamine for sickle cell disease: Knight or pawn?
Sadaf A, Quinn CT. Sadaf A, et al. Exp Biol Med (Maywood). 2020 Jan;245(2):146-154. doi: 10.1177/1535370219900637. Epub 2020 Jan 27. Exp Biol Med (Maywood). 2020. PMID: 31985279 Free PMC article. Review.
IMPACT STATEMENT: L-glutamine has been recently approved by the FDA for the prevention of acute complications in sickle cell disease (SCD). However, there are many gaps in our understanding of the biologic role of glutamine and its therapeutic implications in SCD. T …
IMPACT STATEMENT: L-glutamine has been recently approved by the FDA for the prevention of acute complications in sickle cell disease …
Glutamine Metabolism in Cancer Stem Cells: A Complex Liaison in the Tumor Microenvironment.
Pacifico F, Leonardi A, Crescenzi E. Pacifico F, et al. Int J Mol Sci. 2023 Jan 25;24(3):2337. doi: 10.3390/ijms24032337. Int J Mol Sci. 2023. PMID: 36768660 Free PMC article. Review.
In this review we focus on the role of glutamine in control of cancer stem cell (CSC) fate. We first provide an overview of glutamine metabolism, and then summarize relevant studies investigating how glutamine metabolism modulates the CSC compartment, concent …
In this review we focus on the role of glutamine in control of cancer stem cell (CSC) fate. We first provide an overview of glutam …
Glucose- and glutamine-dependent bioenergetics sensitize bone mechanoresponse after unloading by modulating osteocyte calcium dynamics.
Liu X, Yan Z, Cai J, Wang D, Yang Y, Ding Y, Shao X, Hao X, Luo E, Guo XE, Luo P, Shen L, Jing D. Liu X, et al. J Clin Invest. 2023 Feb 1;133(3):e164508. doi: 10.1172/JCI164508. J Clin Invest. 2023. PMID: 36512405 Free PMC article.
HIF-1alpha also transcriptionally induced substantial glutaminase 2 expression and thereby glutamine addiction in osteocytes. Inhibition of glycolysis by blockade of PDK1 or glutamine supplementation restored the mechanosensitivity in those skeletons with previous u …
HIF-1alpha also transcriptionally induced substantial glutaminase 2 expression and thereby glutamine addiction in osteocytes. Inhibit …
56,481 results
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