Inhibition of glutamine metabolism accelerates resolution of acute lung injury.
Vigeland CL, Beggs HS, Collins SL, Chan-Li Y, Powell JD, Doerschuk CM, Horton MR.
Vigeland CL, et al.
Physiol Rep. 2019 Mar;7(5):e14019. doi: 10.14814/phy2.14019.
Physiol Rep. 2019.
PMID: 30821123
Free PMC article.
Due to their high metabolic needs, neutrophils, macrophages, and lymphocytes rely upon glutamine metabolism to support activation and function. Additionally, during times of physiologic stress, nearly all cells, including fibroblasts and epithelial cells, require …
Due to their high metabolic needs, neutrophils, macrophages, and lymphocytes rely upon glutamine metabolism to support activation and …