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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1923 1
1924 2
1925 5
1926 3
1927 4
1928 1
1929 3
1930 7
1931 3
1932 5
1933 7
1934 4
1935 6
1936 5
1937 2
1938 3
1939 4
1941 2
1943 4
1945 6
1946 8
1947 18
1948 12
1949 16
1950 28
1951 50
1952 50
1953 61
1954 42
1955 45
1956 54
1957 47
1958 72
1959 62
1960 56
1961 75
1962 91
1963 151
1964 264
1965 226
1966 213
1967 226
1968 281
1969 305
1970 324
1971 333
1972 312
1973 347
1974 370
1975 441
1976 471
1977 437
1978 502
1979 562
1980 699
1981 726
1982 835
1983 944
1984 1159
1985 1143
1986 1289
1987 1354
1988 1539
1989 1602
1990 1778
1991 2019
1992 2250
1993 2436
1994 2671
1995 2960
1996 3147
1997 3257
1998 3293
1999 3371
2000 3844
2001 3968
2002 4216
2003 4558
2004 4871
2005 5397
2006 5261
2007 5397
2008 5418
2009 5625
2010 6152
2011 6539
2012 6964
2013 7270
2014 7353
2015 7317
2016 7136
2017 7250
2018 7674
2019 7992
2020 8840
2021 9064
2022 9252
2023 8688
2024 9590
2025 9207
2026 82

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198,132 results

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Page 1
The antioxidant glutathione.
Averill-Bates DA. Averill-Bates DA. Vitam Horm. 2023;121:109-141. doi: 10.1016/bs.vh.2022.09.002. Epub 2023 Jan 13. Vitam Horm. 2023. PMID: 36707132
Reduced glutathione (GSH) is an essential non-enzymatic antioxidant in mammalian cells. GSH can act directly as an antioxidant to protect cells against free radicals and pro-oxidants, and as a cofactor for antioxidant and detoxification enzymes such as glutathione p …
Reduced glutathione (GSH) is an essential non-enzymatic antioxidant in mammalian cells. GSH can act directly as an antioxidant to pro …
Glutathione: subcellular distribution and membrane transport (1).
Oestreicher J, Morgan B. Oestreicher J, et al. Biochem Cell Biol. 2019 Jun;97(3):270-289. doi: 10.1139/bcb-2018-0189. Epub 2018 Nov 14. Biochem Cell Biol. 2019. PMID: 30427707 Review.
Whilst glutathione transport is essential for the supply and replenishment of subcellular glutathione pools, recent evidence supports a more active role for glutathione transport in the regulation of subcellular glutathione redox homeostasis. ...In thi …
Whilst glutathione transport is essential for the supply and replenishment of subcellular glutathione pools, recent evidence s …
Glutathione-dependent bioactivation of xenobiotics.
Dekant W, Vamvakas S. Dekant W, et al. Xenobiotica. 1993 Aug;23(8):873-87. doi: 10.3109/00498259309059415. Xenobiotica. 1993. PMID: 8284943 Review.
Glutathione conjugation has been identified as an important detoxication reaction. However, in recent years several glutathione-dependent bioactivation reactions have been identified. ...Vicinal dihaloalkanes are transformed by glutathione S-transferase-catal
Glutathione conjugation has been identified as an important detoxication reaction. However, in recent years several glutathione
A Review of Dietary (Phyto)Nutrients for Glutathione Support.
Minich DM, Brown BI. Minich DM, et al. Nutrients. 2019 Sep 3;11(9):2073. doi: 10.3390/nu11092073. Nutrients. 2019. PMID: 31484368 Free PMC article. Review.
The diverse roles of glutathione in physiology are relevant to a considerable body of evidence suggesting that glutathione status may be an important biomarker and treatment target in various chronic, age-related diseases. ...Nonetheless, human clinical research sug …
The diverse roles of glutathione in physiology are relevant to a considerable body of evidence suggesting that glutathione sta …
Glutathione analogues in cancer treatment.
Hamilton D, Batist G. Hamilton D, et al. Curr Oncol Rep. 2004 Mar;6(2):116-22. doi: 10.1007/s11912-004-0023-4. Curr Oncol Rep. 2004. PMID: 14751089 Review.
Several glutathione analogues that target this system have been developed and used experimentally and clinically in an attempt to improve cancer chemotherapy. These compounds include glutathione-S-transferase inhibitors and prodrugs, glyoxalase I inhibitors, and S-n …
Several glutathione analogues that target this system have been developed and used experimentally and clinically in an attempt to imp …
Glutathione in defense and signaling: lessons from a small thiol.
Dickinson DA, Forman HJ. Dickinson DA, et al. Ann N Y Acad Sci. 2002 Nov;973:488-504. doi: 10.1111/j.1749-6632.2002.tb04690.x. Ann N Y Acad Sci. 2002. PMID: 12485918 Review.
The major pathways for GSH metabolism in defense of the cell are reduction of hydroperoxides by glutathione peroxidases (GSHPx) and some peroxiredoxins, which yield glutathione disulfide (GSSG), and conjugation reactions catalyzed by glutathione-S-transferase …
The major pathways for GSH metabolism in defense of the cell are reduction of hydroperoxides by glutathione peroxidases (GSHPx) and s …
Cisplatin chemotherapy and renal function.
Zhang J, Ye ZW, Tew KD, Townsend DM. Zhang J, et al. Adv Cancer Res. 2021;152:305-327. doi: 10.1016/bs.acr.2021.03.008. Epub 2021 Apr 28. Adv Cancer Res. 2021. PMID: 34353441 Free PMC article. Review.
Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.
Hayes JD, McLellan LI. Hayes JD, et al. Free Radic Res. 1999 Oct;31(4):273-300. doi: 10.1080/10715769900300851. Free Radic Res. 1999. PMID: 10517533 Review.
Thus, glutathione provides the cell with multiple defences not only against ROS but also against their toxic products. This article discusses how glutathione biosynthesis, glutathione peroxidases, glutathione S-transferases and glutathione S-con …
Thus, glutathione provides the cell with multiple defences not only against ROS but also against their toxic products. This article d …
Glutathione and glutathione analogues; therapeutic potentials.
Wu JH, Batist G. Wu JH, et al. Biochim Biophys Acta. 2013 May;1830(5):3350-3. doi: 10.1016/j.bbagen.2012.11.016. Epub 2012 Nov 28. Biochim Biophys Acta. 2013. PMID: 23201199 Review.
BACKGROUND: Glutathione (GSH) and related enzymes are critical to cell protection from toxins, both endogenous and environmental, including a number of anti-cancer cytotoxic agents. ...This article is part of a Special Issue entitled Cellular functions of glutathione
BACKGROUND: Glutathione (GSH) and related enzymes are critical to cell protection from toxins, both endogenous and environmental, inc …
Cellular glutathione and thiols metabolism.
Dickinson DA, Forman HJ. Dickinson DA, et al. Biochem Pharmacol. 2002 Sep;64(5-6):1019-26. doi: 10.1016/s0006-2952(02)01172-3. Biochem Pharmacol. 2002. PMID: 12213601 Review.
Low molecular weight thiol-containing compounds have an essential role in many biochemical and pharmacological reactions due to the ease with each they are oxidized, and the rapidity with which they can be regenerated. Thioredoxin and glutathione (GSH) are two of the major …
Low molecular weight thiol-containing compounds have an essential role in many biochemical and pharmacological reactions due to the ease wit …
198,132 results
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