Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1975 1
1979 1
1980 1
1981 1
1983 1
1984 2
1985 1
1986 7
1988 1
1989 3
1990 1
1991 5
1992 5
1993 4
1994 7
1995 11
1996 6
1997 10
1998 9
1999 6
2000 8
2001 13
2002 9
2003 7
2004 17
2005 15
2006 10
2007 22
2008 12
2009 18
2010 24
2011 20
2012 27
2013 26
2014 16
2015 26
2016 28
2017 23
2018 27
2019 14
2020 9
Text availability
Article attribute
Article type
Publication date

Search Results

410 results
Results by year
Filters applied: . Clear all
Page 1
Antiviral and immunomodulatory properties of new pro-glutathione (GSH) molecules.
Fraternale A, Paoletti MF, Casabianca A, Oiry J, Clayette P, Vogel JU, Cinatl J Jr, Palamara AT, Sgarbanti R, Garaci E, Millo E, Benatti U, Magnani M. Fraternale A, et al. Curr Med Chem. 2006;13(15):1749-55. doi: 10.2174/092986706777452542. Curr Med Chem. 2006. PMID: 16787218 Review.
Decreased glutathione levels have been found in numerous diseases such as cancer, viral infections, and immune dysfunctions. ...The observations reported herein show that pro-GSH molecules represent new therapeutic agents to treat antiviral infections and Th2 …
Decreased glutathione levels have been found in numerous diseases such as cancer, viral infections, and immune dysfunctions. ...The o …
Boosting GSH Using the Co-Drug Approach: I-152, a Conjugate of N-acetyl-cysteine and β-mercaptoethylamine.
Crinelli R, Zara C, Smietana M, Retini M, Magnani M, Fraternale A. Crinelli R, et al. Nutrients. 2019 Jun 7;11(6):1291. doi: 10.3390/nu11061291. Nutrients. 2019. PMID: 31181621 Free PMC article. Review.
Glutathione (GSH) has poor pharmacokinetic properties; thus, several derivatives and biosynthetic precursors have been proposed as GSH-boosting drugs. ...In this review, the in-vitro and in-vivo metabolism, pro-GSH activity and antiviral and immunomodulatory
Glutathione (GSH) has poor pharmacokinetic properties; thus, several derivatives and biosynthetic precursors have been propose
Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells.
Adedoyin O, Boddu R, Traylor A, Lever JM, Bolisetty S, George JF, Agarwal A. Adedoyin O, et al. Am J Physiol Renal Physiol. 2018 May 1;314(5):F702-F714. doi: 10.1152/ajprenal.00044.2017. Epub 2017 May 17. Am J Physiol Renal Physiol. 2018. PMID: 28515173 Free PMC article.
Heme oxygenase-1 (HO-1) is a cytoprotective enzyme induced in response to cellular stress, and is protective against AKI because of its antiapoptotic and anti-inflammatory properties. ...Cotreatment with ferrostatin-1 (ferroptosis inhibitor), deferoxamine (iron chelator), …
Heme oxygenase-1 (HO-1) is a cytoprotective enzyme induced in response to cellular stress, and is protective against AKI because of its anti …
Antioxidants can increase melanoma metastasis in mice.
Le Gal K, Ibrahim MX, Wiel C, Sayin VI, Akula MK, Karlsson C, Dalin MG, Akyürek LM, Lindahl P, Nilsson J, Bergo MO. Le Gal K, et al. Sci Transl Med. 2015 Oct 7;7(308):308re8. doi: 10.1126/scitranslmed.aad3740. Sci Transl Med. 2015. PMID: 26446958
Similarly, NAC and the soluble vitamin E analog Trolox markedly increased the migration and invasive properties of human malignant melanoma cells but did not affect their proliferation. Both antioxidants increased the ratio between reduced and oxidized glutathione i …
Similarly, NAC and the soluble vitamin E analog Trolox markedly increased the migration and invasive properties of human malignant me …
Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties.
Diotallevi M, Checconi P, Palamara AT, Celestino I, Coppo L, Holmgren A, Abbas K, Peyrot F, Mengozzi M, Ghezzi P. Diotallevi M, et al. Front Immunol. 2017 Sep 29;8:1239. doi: 10.3389/fimmu.2017.01239. eCollection 2017. Front Immunol. 2017. PMID: 29033950 Free PMC article.
Glutathione (GSH), a major cellular antioxidant, is considered an inhibitor of the inflammatory response involving reactive oxygen species (ROS). ...Consequently, GSH depletion prevented the LPS-induced activation of antiviral response and its inhibition of influenz
Glutathione (GSH), a major cellular antioxidant, is considered an inhibitor of the inflammatory response involving reactive oxygen sp
N-Acetyl Cysteine and Vitamin D Supplementation in Treatment Resistant Obsessive-compulsive Disorder Patients: A General Review.
di Michele F, Siracusano A, Talamo A, Niolu C. di Michele F, et al. Curr Pharm Des. 2018;24(17):1832-1838. doi: 10.2174/1381612824666180417124919. Curr Pharm Des. 2018. PMID: 29663874 Review.
RESULTS: The possible benefit mechanisms of NAC for this disorder will be discussed, as well as the role of vitamin D supplementation, given its specific property of stimulating the formation of glutathione in the brain. ...
RESULTS: The possible benefit mechanisms of NAC for this disorder will be discussed, as well as the role of vitamin D supplementation, given …
The effect of N-acetylcysteine (NAC) on human cognition - A systematic review.
Skvarc DR, Dean OM, Byrne LK, Gray L, Lane S, Lewis M, Fernandes BS, Berk M, Marriott A. Skvarc DR, et al. Neurosci Biobehav Rev. 2017 Jul;78:44-56. doi: 10.1016/j.neubiorev.2017.04.013. Epub 2017 Apr 21. Neurosci Biobehav Rev. 2017. PMID: 28438466 Review.
N-acetylcysteine (NAC) is a glutathione precursor with potent antioxidant, pro-neurogenesis and anti-inflammatory properties and a favourable safety profile. ...
N-acetylcysteine (NAC) is a glutathione precursor with potent antioxidant, pro-neurogenesis and anti-inflammatory properties a …
New synthetic glutathione derivatives with increased antiviral activities.
Palamara AT, Brandi G, Rossi L, Millo E, Benatti U, Nencioni L, Iuvara A, Garaci E, Magnani M. Palamara AT, et al. Antivir Chem Chemother. 2004 Mar;15(2):83-91. doi: 10.1177/095632020401500204. Antivir Chem Chemother. 2004. PMID: 15185726 Free article.
A series of glutathione (GSH) derivatives with aliphatic chains of different lengths, coupled by peptides bound to the alpha-NH2 group of Glu, were synthesized. ...Thus, GSH derivatives with increased hydrophobic properties are more effective antiviral age
A series of glutathione (GSH) derivatives with aliphatic chains of different lengths, coupled by peptides bound to the alpha-NH2 grou …
Antiviral and Antioxidant Activity of a Hydroalcoholic Extract from Humulus lupulus L.
Di Sotto A, Checconi P, Celestino I, Locatelli M, Carissimi S, De Angelis M, Rossi V, Limongi D, Toniolo C, Martinoli L, Di Giacomo S, Palamara AT, Nencioni L. Di Sotto A, et al. Oxid Med Cell Longev. 2018 Jul 24;2018:5919237. doi: 10.1155/2018/5919237. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30140367 Free PMC article.
Since HOP extract was able to restore the reducing conditions of infected cells, by increasing glutathione content, its antiviral activity might be also due to an interference with redox-sensitive pathways required for viral replication. ...At phytochemical analysis …
Since HOP extract was able to restore the reducing conditions of infected cells, by increasing glutathione content, its antiviral
A minireview on N-acetylcysteine: An old drug with new approaches.
Elbini Dhouib I, Jallouli M, Annabi A, Gharbi N, Elfazaa S, Lasram MM. Elbini Dhouib I, et al. Life Sci. 2016 Apr 15;151:359-363. doi: 10.1016/j.lfs.2016.03.003. Epub 2016 Mar 2. Life Sci. 2016. PMID: 26946308 Review.
N-acetylcysteine (NAC), a cysteine pro-drug and glutathione precursor has been used in therapeutic practices for several decades, as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication. ...The possible mechanisms of action may b …
N-acetylcysteine (NAC), a cysteine pro-drug and glutathione precursor has been used in therapeutic practices for several decades, as …
410 results
Jump to page
Feedback