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1982 2
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64 results

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Page 1
Glutathione S-transferase is a good biomarker in acrylamide induced neurotoxicity and genotoxicity.
Dasari S, Ganjayi MS, Meriga B. Dasari S, et al. Interdiscip Toxicol. 2018 Aug;11(2):115-121. doi: 10.2478/intox-2018-0007. Epub 2019 Mar 2. Interdiscip Toxicol. 2018. PMID: 31719782 Free PMC article. Review.
Glutathione S-transferases (GSTs) are major defence enzymes of the antioxidant enzymatic system. ...AC can interact with DNA and therefore generate mutations. In rats, low level expression of glutathione S-trasferase (GST) decreases both memory and life span. The ma …
Glutathione S-transferases (GSTs) are major defence enzymes of the antioxidant enzymatic system. ...AC can interact with DNA and ther …
Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk.
Huber WW, Parzefall W. Huber WW, et al. Methods Enzymol. 2005;401:307-41. doi: 10.1016/S0076-6879(05)01020-7. Methods Enzymol. 2005. PMID: 16399395 Review.
Whereas the data on a potential procarcinogenic effect in some organs remained inconclusive, epidemiology has clearly revealed coffee drinkers to be at a lower risk of developing cancers of the colon and the liver and possibly of several other organs. ...This chapter discu …
Whereas the data on a potential procarcinogenic effect in some organs remained inconclusive, epidemiology has clearly revealed coffee …
Anti-genotoxicity and glutathione S-transferase activity in mice pretreated with caffeinated and decaffeinated coffee.
Abraham SK, Singh SP. Abraham SK, et al. Food Chem Toxicol. 1999 Jul;37(7):733-9. doi: 10.1016/s0278-6915(99)00053-8. Food Chem Toxicol. 1999. PMID: 10496374
Changes in hepatic sulfhydryl (-SH) content and glutathione S-transferase (GST) activity were evaluated in pretreated animals. Both caffeinated and decaffeinated instant coffee induced a moderate increase in -SH content and GST activity following pretr …
Changes in hepatic sulfhydryl (-SH) content and glutathione S-transferase (GST) activity were evaluated in pretreated a …
Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse.
Lam LK, Sparnins VL, Wattenberg LW. Lam LK, et al. Cancer Res. 1982 Apr;42(4):1193-8. Cancer Res. 1982. PMID: 7059995
Green coffee beans fed in the diet induced increased GSH S-transferase activity in the mucosa of the small intestine and in the liver of mice. A potent compound that induces increased GSH S-transferase activity was isolated from green coffee beans and …
Green coffee beans fed in the diet induced increased GSH S-transferase activity in the mucosa of the small intestine and in th …
Glutathione S-transferase activity: enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents.
Sparnins VL, Venegas PL, Wattenberg LW. Sparnins VL, et al. J Natl Cancer Inst. 1982 Mar;68(3):493-6. J Natl Cancer Inst. 1982. PMID: 6278195
Benzyl isothiocyanate, beta-naphthoflavone, coumarin, alpha-angelicalactone, disulfiram, indole-3-carbinol and indole-3-acetonitrile induced increased glutathione (GSH) S-transferase activity in the liver and small intestine in female ICR/Ha mice. ...In additional w …
Benzyl isothiocyanate, beta-naphthoflavone, coumarin, alpha-angelicalactone, disulfiram, indole-3-carbinol and indole-3-acetonitrile induced …
Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice.
Lam LK, Sparnins VL, Wattenberg LW. Lam LK, et al. J Med Chem. 1987 Aug;30(8):1399-403. doi: 10.1021/jm00391a022. J Med Chem. 1987. PMID: 3612687
The coffee constituents cafestol and kahweol are inducers of the activity of the detoxifying enzyme, glutathione S-transferase in laboratory animals. ...These findings indicate that the furan moiety of cafestol and kahweol is vital to their biological …
The coffee constituents cafestol and kahweol are inducers of the activity of the detoxifying enzyme, glutathione S-t …
Diet, glutathione S-transferases M1 and T1 gene polymorphisms and cancer risk: a systematic review of observational studies.
Karimi E, Abbasnezhad S, Zeraattalab-Motlagh S, Amiri Khosroshahi R, Beh-Afarin SR, Mohammadi H, Yaghmaie M. Karimi E, et al. Br J Nutr. 2025 Mar 14;133(5):623-636. doi: 10.1017/S0007114525000327. Epub 2025 Feb 21. Br J Nutr. 2025. PMID: 39980344
Consequently, a thorough examination is undertaken to clarify the interplay between varying nutrient intake, glutathione S-transferases Mu1 and Theta 1 (GSTM1 & T1) gene variants and susceptibility to cancer development. ...In contrast, heightened levels of protective …
Consequently, a thorough examination is undertaken to clarify the interplay between varying nutrient intake, glutathione S-transferas …
Coffee and liver diseases.
Muriel P, Arauz J. Muriel P, et al. Fitoterapia. 2010 Jul;81(5):297-305. doi: 10.1016/j.fitote.2009.10.003. Epub 2009 Oct 13. Fitoterapia. 2010. PMID: 19825397 Review.
In addition, epidemiological results, taken together, indicate that coffee consumption is inversely related with hepatic cirrhosis; however, they cannot demonstrate a causative role of coffee with prevention of liver injury. Animal models and cell culture studies in …
In addition, epidemiological results, taken together, indicate that coffee consumption is inversely related with hepatic cirrhosis; h …
Placental glutathione S-transferase (GST-P) induction as a potential mechanism for the anti-carcinogenic effect of the coffee-specific components cafestol and kahweol.
Schilter B, Perrin I, Cavin C, Huggett AC. Schilter B, et al. Carcinogenesis. 1996 Nov;17(11):2377-84. doi: 10.1093/carcin/17.11.2377. Carcinogenesis. 1996. PMID: 8968051
The coffee specific diterpenes cafestol and kahweol (C + K) have been reported to be anti-carcinogenic in several animal models. ...The most striking observation was a dose-dependent induction of placental glutathione S-transferase (GST-P) which could …
The coffee specific diterpenes cafestol and kahweol (C + K) have been reported to be anti-carcinogenic in several animal models. ...T …
Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
Huber WW, Teitel CH, Coles BF, King RS, Wiese FW, Kaderlik KR, Casciano DA, Shaddock JG, Mulder GJ, Ilett KF, Kadlubar FF. Huber WW, et al. Environ Mol Mutagen. 2004;44(4):265-76. doi: 10.1002/em.20052. Environ Mol Mutagen. 2004. PMID: 15468054
Coffee drinking has been associated with reduced incidence of colorectal cancer, possibly via chemoprotection/modification of the metabolism of dietary heterocyclic amine carcinogens such as 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) by kahweol and cafestol pa …
Coffee drinking has been associated with reduced incidence of colorectal cancer, possibly via chemoprotection/modification of the met …
64 results