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Page 1
[Gluten Ataxia: Anti-Transglutaminase-6 Antibody as a New Biomarker].
Sato K, Nanri K. Sato K, et al. Brain Nerve. 2017 Aug;69(8):933-940. doi: 10.11477/mf.1416200845. Brain Nerve. 2017. PMID: 28819077 Review. Japanese.
Gluten ataxia is defined as an anti-gliadin antibody positive sporadic ataxia. Recently, it was reported that the presence of anti-transglutaminase-6 (TG6) antibody can be used to diagnose gluten ataxia. Herein, we will review evid …
Gluten ataxia is defined as an anti-gliadin antibody positive sporadic ataxia. Recently, it was reported that the prese …
Transglutaminase 6 antibodies in gluten neuropathy.
Zis P, Rao DG, Sarrigiannis PG, Aeschlimann P, Aeschlimann DP, Sanders D, Grünewald RA, Hadjivassiliou M. Zis P, et al. Dig Liver Dis. 2017 Nov;49(11):1196-1200. doi: 10.1016/j.dld.2017.08.019. Epub 2017 Aug 10. Dig Liver Dis. 2017. PMID: 28886934
BACKGROUND: TG6 antibodies have been shown to be a marker of gluten ataxia but their presence in the context of other neurological manifestations of gluten sensitivity has not been explored. We investigated the presence of TG6 antibodies in gluten neur …
BACKGROUND: TG6 antibodies have been shown to be a marker of gluten ataxia but their presence in the context of other neurolog …
Transglutaminase 6 antibodies in the diagnosis of gluten ataxia.
Hadjivassiliou M, Aeschlimann P, Sanders DS, Mäki M, Kaukinen K, Grünewald RA, Bandmann O, Woodroofe N, Haddock G, Aeschlimann DP. Hadjivassiliou M, et al. Neurology. 2013 May 7;80(19):1740-5. doi: 10.1212/WNL.0b013e3182919070. Epub 2013 Apr 10. Neurology. 2013. PMID: 23576621
OBJECTIVES: The previous finding of an immunologic response primarily directed against transglutaminase (TG)6 in patients with gluten ataxia (GA) led us to investigate the role of TG6 antibodies in diagnosing GA. ...In addition, biopsies from 15 consec …
OBJECTIVES: The previous finding of an immunologic response primarily directed against transglutaminase (TG)6 in patients with …
Autoantibodies in gluten ataxia recognize a novel neuronal transglutaminase.
Hadjivassiliou M, Aeschlimann P, Strigun A, Sanders DS, Woodroofe N, Aeschlimann D. Hadjivassiliou M, et al. Ann Neurol. 2008 Sep;64(3):332-43. doi: 10.1002/ana.21450. Ann Neurol. 2008. PMID: 18825674
RESULTS: Whereas the development of anti-transglutaminase 2 IgA is linked with gastrointestinal disease, an anti-transglutaminase 6 IgG and IgA response is prevalent in gluten ataxia, independent of intestinal involvement. ...Furthermore, postmo …
RESULTS: Whereas the development of anti-transglutaminase 2 IgA is linked with gastrointestinal disease, an anti-transglutaminase …
Serological analysis of gluten-related antibodies in idiopathic neuropathies and cerebellar ataxia.
Rouvroye MD, Warendorf J, Vrancken A, Eftimov F, Wieske L, Faber CG, Hoeijmakers JGJ, Damoiseaux J, van de Warrenburg B, van Gaalen J, van der Molen R, Bouma G, Bontkes H. Rouvroye MD, et al. J Neurol. 2025 Jun 7;272(7):447. doi: 10.1007/s00415-025-13187-w. J Neurol. 2025. PMID: 40481865 Free PMC article.
Immune reactivity to gluten in the development of peripheral neuropathies and cerebellar ataxia has been suggested for decades, but evidence is scarce. The aim of the current study was to test the prevalence of tissue transglutaminase 2 (anti-TG2), tissue …
Immune reactivity to gluten in the development of peripheral neuropathies and cerebellar ataxia has been suggested for decades …
CSF Markers of TG6 Autoimmunity in Gluten Ataxia.
Floare ML, Wharton SB, Simpson JE, Aeschlimann D, Hadjivassiliou M. Floare ML, et al. Cerebellum. 2025 Apr 2;24(3):79. doi: 10.1007/s12311-025-01832-z. Cerebellum. 2025. PMID: 40172737 Free PMC article.
Gluten ataxia (GA) is the primary neurological manifestation of gluten sensitivity, characterised by loss of Purkinje cells throughout the cerebellar cortex and rooted in autoimmunity to transglutaminase 6 (TG6). ...In this observational study w …
Gluten ataxia (GA) is the primary neurological manifestation of gluten sensitivity, characterised by loss of Purkinje c …
Autoantibodies related to ataxia and other central nervous system manifestations of gluten enteropathy.
Velikova T, Vasilev G, Shumnalieva R, Chervenkov L, Miteva DG, Gulinac M, Priftis S, Lazova S. Velikova T, et al. World J Clin Cases. 2024 Apr 26;12(12):2031-2039. doi: 10.12998/wjcc.v12.i12.2031. World J Clin Cases. 2024. PMID: 38680259 Free PMC article. Review.
Gluten ataxia and other central nervous system disorders could be linked to gluten enteropathy and related autoantibodies. In this narrative review, we focus on the various neuro-logical manifestations in patients with gluten sensitivity/celiac disease …
Gluten ataxia and other central nervous system disorders could be linked to gluten enteropathy and related autoantibodi …
Gluten ataxia of sporadic and hereditary cerebellar ataxia in patients from mainland China.
Guan WJ, Liu XJ, Tang BS, Liu YT, Zhou Y, Jiang H, Shen L, Xia K, Wang JL. Guan WJ, et al. Neurol India. 2013 May-Jun;61(3):226-30. doi: 10.4103/0028-3886.115056. Neurol India. 2013. PMID: 23860139 Free article.
AIM: To investigate the prevalence of gluten ataxia among patients with ataxia in China. MATERIALS AND METHODS: Serum levels of anti-gliadin, anti-transglutaminase 2 (TG2), and anti-transglutaminase 6 (TG6) antibodies measured in 125 pati …
AIM: To investigate the prevalence of gluten ataxia among patients with ataxia in China. MATERIALS AND METHODS: Serum l …
Epilepsy, cerebral calcifications, and gluten-related disorders: Are anti-transglutaminase 6 antibodies the missing link?
Ferlazzo E, Polidoro S, Gobbi G, Gasparini S, Sueri C, Cianci V, Sofia V, Giuliano L, Giallonardo AT, Di Bonaventura C, Casciato S, Messana T, Coppola A, Striano S, Bilo L, Monoriti M, Genovese G, Sarica P, Arcudi L, Aguglia U. Ferlazzo E, et al. Seizure. 2019 Dec;73:17-20. doi: 10.1016/j.seizure.2019.10.012. Epub 2019 Oct 16. Seizure. 2019. PMID: 31698178 Free article.
PURPOSE: Gluten-related disorders (GRDs) are a group of immune-mediated diseases often associated to neurologic manifestations. Epilepsies with cerebral calcifications, with or without coeliac disease (CD), are rare neurological disorders characterized by childhood-onset f …
PURPOSE: Gluten-related disorders (GRDs) are a group of immune-mediated diseases often associated to neurologic manifestations. Epile …
Transglutaminase 6 Antibodies in the Serum of Patients With Amyotrophic Lateral Sclerosis.
Gadoth A, Nefussy B, Bleiberg M, Klein T, Artman I, Drory VE. Gadoth A, et al. JAMA Neurol. 2015 Jun;72(6):676-81. doi: 10.1001/jamaneurol.2015.48. JAMA Neurol. 2015. PMID: 25867286
IMPORTANCE: Celiac disease is an autoimmune disorder triggered by gluten in genetically predisposed individuals. Gluten sensitivity can cause neurologic manifestations, such as ataxia or neuropathy, with or without gastrointestinal symptoms. Many patients wit …
IMPORTANCE: Celiac disease is an autoimmune disorder triggered by gluten in genetically predisposed individuals. Gluten sensit …
30 results