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Comparing urine and stool gluten immunogenic peptides for detecting compliance to gluten-free diets.
Gkikas K, Gianolio L, Kavanagh M, White B, Kerbiriou C, Lima M, Svolos V, Hansen R, Russell RK, Gerasimidis K. Gkikas K, et al. Pediatr Res. 2026 Feb;99(3):1181-1186. doi: 10.1038/s41390-025-04266-9. Epub 2025 Jul 24. Pediatr Res. 2026. PMID: 40707834 Free PMC article.
BACKGROUND: Detection of gluten immunogenic peptides (GIP) is a potential objective biomarker of adherence to gluten-free diet (GFD). ...CONCLUSIONS: The S-POC kit is a suitable alternative for GIP detection, demonstrating high sensitivity and specific …
BACKGROUND: Detection of gluten immunogenic peptides (GIP) is a potential objective biomarker of adherence to gluten
AGA Clinical Practice Update on Management of Refractory Celiac Disease: Expert Review.
Green PHR, Paski S, Ko CW, Rubio-Tapia A. Green PHR, et al. Gastroenterology. 2022 Nov;163(5):1461-1469. doi: 10.1053/j.gastro.2022.07.086. Epub 2022 Sep 19. Gastroenterology. 2022. PMID: 36137844 Review.
BEST PRACTICE ADVICE 2: In patients with confirmed celiac disease with persistent or recurrent symptoms or signs (nonresponsive celiac disease), ongoing gluten ingestion should be excluded as a cause of these symptoms with serologic testing, dietitian review, and detection …
BEST PRACTICE ADVICE 2: In patients with confirmed celiac disease with persistent or recurrent symptoms or signs (nonresponsive celiac disea …
Gluten immunogenic peptide excretion detects dietary transgressions in treated celiac disease patients.
Costa AF, Sugai E, Temprano MP, Niveloni SI, Vázquez H, Moreno ML, Domínguez-Flores MR, Muñoz-Suano A, Smecuol E, Stefanolo JP, González AF, Cebolla-Ramirez A, Mauriño E, Verdú EF, Bai JC. Costa AF, et al. World J Gastroenterol. 2019 Mar 21;25(11):1409-1420. doi: 10.3748/wjg.v25.i11.1409. World J Gastroenterol. 2019. PMID: 30918433 Free PMC article.
Recently, tests that determine consumption of gluten by assessing excretion of gluten immunogenic peptides (GIP) in stool and urine have been developed. ...Using the Gastrointestinal Symptom Rating Scale questionnaire, patients were class …
Recently, tests that determine consumption of gluten by assessing excretion of gluten immunogenic peptides (GIP) …
Comparative Effectiveness of Urine vs. Stool Gluten Immunogenic Peptides Testing for Monitoring Gluten Intake in Coeliac Patients: A Systematic Review and Meta-Analysis.
Moghal SS, Soldera J. Moghal SS, et al. Life (Basel). 2025 Oct 2;15(10):1548. doi: 10.3390/life15101548. Life (Basel). 2025. PMID: 41157221 Free PMC article. Review.
This systematic review and meta-analysis aimed to compare the effectiveness of urine versus stool GIPS testing for monitoring gluten intake in coeliac patients, providing evidence-based recommendations for clinical practice. A comprehensive literature search …
This systematic review and meta-analysis aimed to compare the effectiveness of urine versus stool GIPS testing for monitoring …
Stool Gluten Peptide Detection Is Superior to Urinary Analysis, Coeliac Serology, Dietary Adherence Scores and Symptoms in the Detection of Intermittent Gluten Exposure in Coeliac Disease: A Randomised, Placebo-Controlled, Low-Dose Gluten Challenge Study.
Russell AK, Lucas EC, Henneken LM, Pizzey CJ, Clarke D, Myleus A, Tye-Din JA. Russell AK, et al. Nutrients. 2024 Jan 17;16(2):279. doi: 10.3390/nu16020279. Nutrients. 2024. PMID: 38257173 Free PMC article. Clinical Trial.
Monitoring adherence to a gluten-free diet is an important goal of coeliac disease management. Urine and stool gluten immunogenic peptide (GIP) assays provide an objective readout of gluten ingestion, with the former favoured due t …
Monitoring adherence to a gluten-free diet is an important goal of coeliac disease management. Urine and stool glute
Low Levels of Detectable Urine and Stool GIPs in Children with Celiac Disease on a Gluten-Free Diet.
Horton M, Olshan KL, Gleeson E, Regis S, Morson T, Hintze ZJ, Leonard MM, Silvester JA. Horton M, et al. JPGN Rep. 2023 Jun 9;4(3):e323. doi: 10.1097/PG9.0000000000000323. eCollection 2023 Aug. JPGN Rep. 2023. PMID: 37600614 Free PMC article. Clinical Trial.
OBJECTIVES: This study examines the prevalence of detectable gluten immunogenic peptides (GIPs) as a proxy for gluten exposure in children with celiac disease on a gluten-free diet in the United States, as estimated by gluten breakdown pr …
OBJECTIVES: This study examines the prevalence of detectable gluten immunogenic peptides (GIPs) as a proxy for glute
Real-World Gluten Exposure in Patients With Celiac Disease on Gluten-Free Diets, Determined From Gliadin Immunogenic Peptides in Urine and Fecal Samples.
Stefanolo JP, Tálamo M, Dodds S, de la Paz Temprano M, Costa AF, Moreno ML, Pinto-Sánchez MI, Smecuol E, Vázquez H, Gonzalez A, Niveloni SI, Mauriño E, Verdu EF, Bai JC. Stefanolo JP, et al. Clin Gastroenterol Hepatol. 2021 Mar;19(3):484-491.e1. doi: 10.1016/j.cgh.2020.03.038. Epub 2020 Mar 23. Clin Gastroenterol Hepatol. 2021. PMID: 32217152
BACKGROUND & AIMS: It is not clear how often patients who are on gluten-free diets (GFDs) for treatment of celiac disease still are exposed to gluten. We studied levels of gluten immunogenic peptides (GIP) in fecal and urine samples, …
BACKGROUND & AIMS: It is not clear how often patients who are on gluten-free diets (GFDs) for treatment of celiac disease still a …
Biomarkers to Monitor Adherence to Gluten-Free Diet by Celiac Disease Patients: Gluten Immunogenic Peptides and Urinary miRNAs.
Paolini A, Sarshar M, Felli C, Bruno SP, Rostami-Nejad M, Ferretti F, Masotti A, Baldassarre A. Paolini A, et al. Foods. 2022 May 10;11(10):1380. doi: 10.3390/foods11101380. Foods. 2022. PMID: 35626950 Free PMC article. Review.
To this aim, small gluten immunogenic peptides (GIPs) obtained by the hydrolysis of gluten and present in urine and feces have been studied as biomarkers of gluten intake and to monitor adherence to GFD by CD patients. ...Moreover, …
To this aim, small gluten immunogenic peptides (GIPs) obtained by the hydrolysis of gluten and present in uri
Determination of gluten immunogenic peptides for the management of the treatment adherence of celiac disease: A systematic review.
Coto L, Mendia I, Sousa C, Bai JC, Cebolla A. Coto L, et al. World J Gastroenterol. 2021 Oct 7;27(37):6306-6321. doi: 10.3748/wjg.v27.i37.6306. World J Gastroenterol. 2021. PMID: 34712034 Free PMC article.
Gluten immunogenic peptides (GIP) are resistant to gastrointestinal digestion and are then excreted via the stool and urine. ...METHODS: PubMed and Web of Science searches were performed using the keywords "gluten immunogenic pe
Gluten immunogenic peptides (GIP) are resistant to gastrointestinal digestion and are then excreted via the stool
Gluten Immunogenic Peptides Are Not Correlated With Reported Adherence to Gluten-Free Diet in Children With Celiac Disease.
Guz-Mark A, Perets TT, Biran N, Jack Y, Zevit N, Silbermintz A, Matar M, Nachmias-Friedler V, Waisbourd-Zinman O, Bar-Lev MR, Huta Y, Ashorov O, Gingold-Belfer R, Shamir R. Guz-Mark A, et al. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):244-248. doi: 10.1097/MPG.0000000000003835. Epub 2023 May 19. J Pediatr Gastroenterol Nutr. 2023. PMID: 37204826
OBJECTIVE: There is no gold standard to assess adherence to gluten-free diet (GFD) among patients with celiac disease (CeD). Gluten immunogenic peptides (GIPs) in urine and stool were suggested as novel markers for evaluating adherence to …
OBJECTIVE: There is no gold standard to assess adherence to gluten-free diet (GFD) among patients with celiac disease (CeD). Glute
21 results