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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
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1964 4
1965 5
1966 2
1967 4
1968 6
1969 9
1970 7
1971 8
1972 13
1973 15
1974 4
1975 11
1976 10
1977 7
1978 4
1979 8
1980 5
1981 2
1982 5
1983 5
1984 7
1985 3
1986 4
1987 5
1988 5
1989 4
1990 3
1991 3
1992 8
1993 6
1994 1
1995 3
1996 5
1997 6
1998 3
1999 7
2000 5
2001 3
2002 2
2003 6
2004 5
2005 9
2006 10
2007 3
2008 10
2009 8
2010 8
2011 12
2012 5
2013 12
2014 11
2015 11
2016 8
2017 11
2018 10
2019 11
2020 4
2021 12
2022 10
2023 10
2024 20
2025 15
2026 11

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424 results

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Page 1
Roles of dietary glycine, proline, and hydroxyproline in collagen synthesis and animal growth.
Li P, Wu G. Li P, et al. Amino Acids. 2018 Jan;50(1):29-38. doi: 10.1007/s00726-017-2490-6. Epub 2017 Sep 20. Amino Acids. 2018. PMID: 28929384 Review.
Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen, which accounts for one-third of proteins in animals. ...Results of the recent studies indicate that endogenous synthesis of glycine, proline …
Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen, which accounts for …
Metabolic control of collagen synthesis.
Guillard J, Schwörer S. Guillard J, et al. Matrix Biol. 2024 Nov;133:43-56. doi: 10.1016/j.matbio.2024.07.003. Epub 2024 Jul 29. Matrix Biol. 2024. PMID: 39084474 Free PMC article. Review.
Previous efforts to target aberrant collagen synthesis in fibroblasts by inhibiting pro-fibrotic signaling cascades have been ineffective. More recently, metabolic rewiring downstream of pro-fibrotic signaling has emerged as a critical regulator of collagen …
Previous efforts to target aberrant collagen synthesis in fibroblasts by inhibiting pro-fibrotic signaling cascades have been …
Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis.
Shaw G, Lee-Barthel A, Ross ML, Wang B, Baar K. Shaw G, et al. Am J Clin Nutr. 2017 Jan;105(1):136-143. doi: 10.3945/ajcn.116.138594. Epub 2016 Nov 16. Am J Clin Nutr. 2017. PMID: 27852613 Free PMC article. Clinical Trial.
Nutritional and/or exercise interventions that increase collagen synthesis and strengthen these tissues could have an important effect on injury rates. ...Blood was drawn before and 4, 24, 48, and 72 h after the first exercise bout for determination of amino-termina …
Nutritional and/or exercise interventions that increase collagen synthesis and strengthen these tissues could have an importan …
Collagens.
Gordon MK, Hahn RA. Gordon MK, et al. Cell Tissue Res. 2010 Jan;339(1):247-57. doi: 10.1007/s00441-009-0844-4. Epub 2009 Aug 20. Cell Tissue Res. 2010. PMID: 19693541 Free PMC article. Review.
The three alpha chains that form the triple helical part of the molecule are composed of repeating peptide triplets of glycine-X-Y. X and Y can be any amino acid but are often proline and hydroxyproline, respectively. Flanking the triple helical regions (i.e., Col d …
The three alpha chains that form the triple helical part of the molecule are composed of repeating peptide triplets of glycine-X-Y. X …
Control analysis of collagen synthesis by glycine, proline and lysine in bovine chondrocytes in vitro - Its relevance for medicine and nutrition.
de Paz-Lugo P, Lupiáñez JA, Sicilia J, Meléndez-Hevia E. de Paz-Lugo P, et al. Biosystems. 2023 Oct;232:105004. doi: 10.1016/j.biosystems.2023.105004. Epub 2023 Aug 19. Biosystems. 2023. PMID: 37598999
We have applied the Metabolic Control Analysis approach to study the control of collagen synthesis flux by means of the response coefficients of the flux with respect to glycine, proline and lysine. Our results show that the main cause of the procollag …
We have applied the Metabolic Control Analysis approach to study the control of collagen synthesis flux by means of the respon …
The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling: a narrative review.
Holwerda AM, van Loon LJC. Holwerda AM, et al. Nutr Rev. 2022 May 9;80(6):1497-1514. doi: 10.1093/nutrit/nuab083. Nutr Rev. 2022. PMID: 34605901 Free PMC article. Review.
In contrast, recent evidence demonstrates that protein ingestion does not increase muscle connective tissue protein synthesis. The absence of an increase in muscle connective tissue protein synthesis after protein ingestion may be explained by insufficient provision …
In contrast, recent evidence demonstrates that protein ingestion does not increase muscle connective tissue protein synthesis. The ab …
Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness.
Rachedi NS, Tang Y, Tai YY, Zhao J, Chauvet C, Grynblat J, Akoumia KKF, Estephan L, Torrino S, Sbai C, Ait-Mouffok A, Latoche JD, Al Aaraj Y, Brau F, Abélanet S, Clavel S, Zhang Y, Guillermier C, Kumar NVG, Tavakoli S, Mercier O, Risbano MG, Yao ZK, Yang G, Ouerfelli O, Lewis JS, Montani D, Humbert M, Steinhauser ML, Anderson CJ, Oldham WM, Perros F, Bertero T, Chan SY. Rachedi NS, et al. Cell Metab. 2024 Jun 4;36(6):1335-1350.e8. doi: 10.1016/j.cmet.2024.04.010. Epub 2024 May 2. Cell Metab. 2024. PMID: 38701775 Free PMC article.
Whether and how vascular fibroblasts rewire their metabolism to sustain collagen biosynthesis remains unknown. Here, we found that inflammation, hypoxia, and mechanical stress converge on activating the transcriptional coactivators YAP and TAZ (WWTR1) in pulmonary a …
Whether and how vascular fibroblasts rewire their metabolism to sustain collagen biosynthesis remains unknown. Here, we found …
Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging.
Rahman A, Rehmani R, Pirvu DG, Huang SM, Puri S, Arcos M. Rahman A, et al. Mar Drugs. 2024 Mar 30;22(4):159. doi: 10.3390/md22040159. Mar Drugs. 2024. PMID: 38667776 Free PMC article. Review.
Notably, collagen supplements enriched with essential amino acids such as proline and glycine, along with marine fish collagen, have become popular for their safety and effectiveness in mitigating the aging process. ...Furthermore, the topical applicat …
Notably, collagen supplements enriched with essential amino acids such as proline and glycine, along with marine fish …
MMP generated matrikines.
Wells JM, Gaggar A, Blalock JE. Wells JM, et al. Matrix Biol. 2015 May-Jul;44-46:122-9. doi: 10.1016/j.matbio.2015.01.016. Epub 2015 Jan 28. Matrix Biol. 2015. PMID: 25636538 Free PMC article. Review.
Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP). Elastin peptide fragments are generated by elastolytic enzymes and …
Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly …
Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts.
Hamanaka RB, O'Leary EM, Witt LJ, Tian Y, Gökalp GA, Meliton AY, Dulin NO, Mutlu GM. Hamanaka RB, et al. Am J Respir Cell Mol Biol. 2019 Nov;61(5):597-606. doi: 10.1165/rcmb.2019-0008OC. Am J Respir Cell Mol Biol. 2019. PMID: 30973753 Free PMC article.
Instead, we discovered that the glutamate-consuming enzymes phosphoserine aminotransferase 1 (PSAT1) and aldehyde dehydrogenase 18A1 (ALDH18A1)/delta(1)-pyrroline-5-carboxylate synthetase (P5CS) are required for collagen protein production by lung fibroblasts. PSAT1 is req …
Instead, we discovered that the glutamate-consuming enzymes phosphoserine aminotransferase 1 (PSAT1) and aldehyde dehydrogenase 18A1 (ALDH18 …
424 results