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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1972 2
1973 2
1974 7
1975 10
1976 16
1977 15
1978 23
1979 30
1980 59
1981 72
1982 89
1983 93
1984 123
1985 120
1986 120
1987 113
1988 142
1989 131
1990 129
1991 139
1992 157
1993 145
1994 178
1995 184
1996 158
1997 202
1998 214
1999 223
2000 240
2001 225
2002 244
2003 285
2004 273
2005 300
2006 314
2007 293
2008 310
2009 285
2010 310
2011 272
2012 304
2013 337
2014 315
2015 265
2016 268
2017 282
2018 298
2019 276
2020 299
2021 280
2022 251
2023 213
2024 246
2025 268
2026 133

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9,393 results

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Page 1
Gonadotropin-releasing-hormone-receptor antagonists.
Huirne JA, Lambalk CB. Huirne JA, et al. Lancet. 2001 Nov 24;358(9295):1793-803. doi: 10.1016/S0140-6736(01)06797-6. Lancet. 2001. PMID: 11734258 Review.
Pulsatile gonadotropin-releasing hormone (GnRH) stimulates the pituitary secretion of both luteinising hormone (LH) and follicle-stimulating hormone (FSH) and thus controls the hormonal and reproductive function of the gonads. ...Selectiv …
Pulsatile gonadotropin-releasing hormone (GnRH) stimulates the pituitary secretion of both luteinising hormon …
Gonadotropin-Releasing Hormone and GnRH Receptor: Structure, Function and Drug Development.
Tzoupis H, Nteli A, Androutsou ME, Tselios T. Tzoupis H, et al. Curr Med Chem. 2020;27(36):6136-6158. doi: 10.2174/0929867326666190712165444. Curr Med Chem. 2020. PMID: 31309882 Review.
BACKGROUND: Gonadotropin-Releasing Hormone (GnRH) is a key element in sexual maturation and regulation of the reproductive cycle in the human organism. GnRH interacts with the pituitary cells through the activation of the Gonadotropin …
BACKGROUND: Gonadotropin-Releasing Hormone (GnRH) is a key element in sexual maturation and regulation of the re …
Gonadotropin-releasing hormone: GnRH receptor signaling in extrapituitary tissues.
Cheung LW, Wong AS. Cheung LW, et al. FEBS J. 2008 Nov;275(22):5479-95. doi: 10.1111/j.1742-4658.2008.06677.x. FEBS J. 2008. PMID: 18959738 Free article. Review.
Gonadotropin-releasing hormone (GnRH) has historically been known as a pituitary hormone; however, in the past few years, interest has been raised in locally produced, extrapituitary GnRH. GnRH receptor (GnRHR) was found to …
Gonadotropin-releasing hormone (GnRH) has historically been known as a pituitary hormone; however, in the …
Linzagolix: First Approval.
Keam SJ. Keam SJ. Drugs. 2022 Aug;82(12):1317-1325. doi: 10.1007/s40265-022-01753-9. Drugs. 2022. PMID: 35997940 Free PMC article. Review.
Linzagolix (Yselty( )) is an orally administered, selective, non-peptide small molecule gonadotrophin releasing hormone (GnRH) receptor antagonist that is being developed by Kissei Pharmaceutical for the treatment of uterine fibroids and endometriosis …
Linzagolix (Yselty( )) is an orally administered, selective, non-peptide small molecule gonadotrophin releasing hormone (Gn …
Mammalian gonadotropin-releasing hormone (GnRH) receptor subtypes.
Neill JD. Neill JD. Arch Physiol Biochem. 2002 Apr;110(1-2):129-36. doi: 10.1076/apab.110.1.129.900. Arch Physiol Biochem. 2002. PMID: 11935410
Mammalian gonadotropin-releasing hormone (GnRH I) is a hypothalamic decapeptide that governs gonadotropin secretion through interaction with its seven transmembrane (7TM), G protein-coupled receptor (GPCR) expressed by anterior pituitary …
Mammalian gonadotropin-releasing hormone (GnRH I) is a hypothalamic decapeptide that governs gonadotropin …
AXL receptor tyrosine kinase modulates gonadotropin-releasing hormone receptor signaling.
Mohammadzadeh P, Roueinfar M, Amberg GC. Mohammadzadeh P, et al. Cell Commun Signal. 2023 Oct 12;21(1):284. doi: 10.1186/s12964-023-01313-y. Cell Commun Signal. 2023. PMID: 37828510 Free PMC article.
BACKGROUND: Gonadotropin-releasing hormone (GnRH) receptors are essential for reproduction and are expressed in numerous urogenital, reproductive, and non-reproductive cancers. In addition to canonical G protein-coupled receptor signaling …
BACKGROUND: Gonadotropin-releasing hormone (GnRH) receptors are essential for reproduction and are expres …
Gonadotropin-releasing hormone receptor inhibits triple-negative breast cancer proliferation and metastasis.
Chen CP, Lu X. Chen CP, et al. J Int Med Res. 2022 Mar;50(3):3000605221082895. doi: 10.1177/03000605221082895. J Int Med Res. 2022. PMID: 35264044 Free PMC article.
BACKGROUND: Gonadotropin-releasing hormone receptor (GnRHR) is expressed in several malignant tumors and inhibits the proliferation and metastasis of cancer cells, but its role in triple-negative breast cancers (TNBCs) is unclear. ...RESULTS: GnRHR mRN …
BACKGROUND: Gonadotropin-releasing hormone receptor (GnRHR) is expressed in several malignant tumors and inhibit …
Gonadotropin-releasing hormone receptor system: modulatory role in aging and neurodegeneration.
Wang L, Chadwick W, Park SS, Zhou Y, Silver N, Martin B, Maudsley S. Wang L, et al. CNS Neurol Disord Drug Targets. 2010 Nov;9(5):651-60. doi: 10.2174/187152710793361559. CNS Neurol Disord Drug Targets. 2010. PMID: 20632963 Free PMC article. Review.
Age-related decline in gonadal reproductive hormones cause imbalances of this axis and many hormones in this axis have been functionally linked to neurodegenerative pathophysiology. Gonadotropin-releasing hormone (GnRH) plays a vital role in both centr …
Age-related decline in gonadal reproductive hormones cause imbalances of this axis and many hormones in this axis have been functionally lin …
Gonadotropin-releasing hormone/gonadotropin-releasing hormone receptor signaling in the placenta.
Sasaki K, Norwitz ER. Sasaki K, et al. Curr Opin Endocrinol Diabetes Obes. 2011 Dec;18(6):401-8. doi: 10.1097/MED.0b013e32834cd3b0. Curr Opin Endocrinol Diabetes Obes. 2011. PMID: 22024993 Review.
PURPOSE OF REVIEW: This review summarizes our current understanding of the role of gonadotropin-releasing hormone (GnRH)/GnRH receptor (GnRHR) signaling at the maternal-fetal interface. ...Although several putative isoforms of GnRHR have …
PURPOSE OF REVIEW: This review summarizes our current understanding of the role of gonadotropin-releasing hormone (G …
9,393 results