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Towards Personalized Management of Sarcopenia in COPD.

van Bakel SIJ, Gosker HR, Langen RC, Schols AMWJ. van Bakel SIJ, et al. Among authors: gosker hr. Int J Chron Obstruct Pulmon Dis. 2021 Jan 7;16:25-40. doi: 10.2147/COPD.S280540. eCollection 2021. Int J Chron Obstruct Pulmon Dis. 2021. PMID: 33442246 Free PMC article. Review.

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Role of acute exacerbations in skeletal muscle impairment in COPD.

Gosker HR, Langen RC, Simons SO. Gosker HR, et al. Expert Rev Respir Med. 2021 Jan;15(1):103-115. doi: 10.1080/17476348.2021.1843429. Epub 2020 Nov 10. Expert Rev Respir Med. 2021. PMID: 33131350

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Cognitive performance in relation to metabolic disturbances in patients with COPD.

van Beers M, Gosker HR, Janssen DJA, Cleutjens FAHM, Franssen FME, van Boxtel MPJ, Wouters EF, Ponds RWHM, Schols AMWJ. van Beers M, et al. Among authors: gosker hr. Clin Nutr. 2020 Oct 1:S0261-5614(20)30501-X. doi: 10.1016/j.clnu.2020.09.029. Online ahead of print. Clin Nutr. 2020. PMID: 33041090 Free article.

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Iron deficiency-induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria-containing vesicles.

Leermakers PA, Remels AHV, Zonneveld MI, Rouschop KMA, Schols AMWJ, Gosker HR. Leermakers PA, et al. Among authors: gosker hr. FASEB J. 2020 May;34(5):6703-6717. doi: 10.1096/fj.201901815R. Epub 2020 Mar 23. FASEB J. 2020. PMID: 32202346

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Recovery of muscle mass and muscle oxidative phenotype following disuse does not require GSK-3 inactivation.

Theeuwes WF, Pansters NAM, Gosker HR, Schols AMWJ, Verhees KJP, de Theije CC, van Gorp RHP, Kelders MCJM, Ronda O, Haegens A, Remels AHV, Langen RCJ. Theeuwes WF, et al. Among authors: gosker hr. Biochim Biophys Acta Mol Basis Dis. 2020 Jun 1;1866(6):165740. doi: 10.1016/j.bbadis.2020.165740. Epub 2020 Feb 19. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32087280 Free article.

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Resveratrol and metabolic health in COPD: A proof-of-concept randomized controlled trial.

Beijers RJ, Gosker HR, Sanders KJ, de Theije C, Kelders M, Clarke G, Cryan JF, van den Borst B, Schols AM. Beijers RJ, et al. Among authors: gosker hr. Clin Nutr. 2020 Oct;39(10):2989-2997. doi: 10.1016/j.clnu.2020.01.002. Epub 2020 Jan 13. Clin Nutr. 2020. PMID: 31996311

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Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle.

Leermakers PA, Remels AHV, Langen RCJ, Schols AMWJ, Gosker HR. Leermakers PA, et al. Among authors: gosker hr. BMC Pulm Med. 2020 Jan 21;20(1):20. doi: 10.1186/s12890-020-1047-8. BMC Pulm Med. 2020. PMID: 31964384 Free PMC article.

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Regulation of PGC-1α expression by a GSK-3β-TFEB signaling axis in skeletal muscle.

Theeuwes WF, Gosker HR, Schols AMWJ, Langen RCJ, Remels AHV. Theeuwes WF, et al. Among authors: gosker hr. Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118610. doi: 10.1016/j.bbamcr.2019.118610. Epub 2019 Nov 16. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 31738957 Free article.

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Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation.

Leermakers PA, Kneppers AEM, Schols AMWJ, Kelders MCJM, de Theije CC, Verdijk LB, van Loon LJC, Langen RCJ, Gosker HR. Leermakers PA, et al. Among authors: gosker hr. Muscle Nerve. 2019 Dec;60(6):769-778. doi: 10.1002/mus.26702. Epub 2019 Oct 23. Muscle Nerve. 2019. PMID: 31495926 Free PMC article.

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Impaired Skeletal Muscle Kynurenine Metabolism in Patients with Chronic Obstructive Pulmonary Disease.

Gosker HR, Clarke G, de Theije CC, Cryan JF, Schols AMWJ. Gosker HR, et al. J Clin Med. 2019 Jun 26;8(7):915. doi: 10.3390/jcm8070915. J Clin Med. 2019. PMID: 31247950 Free PMC article.

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