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Page 1
Recent progress of graphene oxide as a potential vaccine carrier and adjuvant.
Cao W, He L, Cao W, Huang X, Jia K, Dai J. Cao W, et al. Acta Biomater. 2020 Aug;112:14-28. doi: 10.1016/j.actbio.2020.06.009. Epub 2020 Jun 10. Acta Biomater. 2020. PMID: 32531395 Review.
Our work describes the surface modification of graphene oxide and for the first time summarizes that functionalized graphene oxide serves as a vaccine carrier and shows significant adjuvant activity in activating cellular and humoral immunity. I …
Our work describes the surface modification of graphene oxide and for the first time summarizes that functionalized graphen …
Graphene oxide as novel vaccine adjuvant.
Vakili B, Karami-Darehnaranji M, Mirzaei E, Hosseini F, Nezafat N. Vakili B, et al. Int Immunopharmacol. 2023 Dec;125(Pt A):111062. doi: 10.1016/j.intimp.2023.111062. Epub 2023 Oct 23. Int Immunopharmacol. 2023. PMID: 37866317 Review.
To improve antigen immunogenicity and promote long-lasting immunity, vaccine formulations have been appropriately supplemented with adjuvants. Graphene has been found to enhance the presentation of antigens to CD8+ T cells, as well as stimulating innate immune responses an …
To improve antigen immunogenicity and promote long-lasting immunity, vaccine formulations have been appropriately supplemented with a …
Graphene oxide nanoarchitectures in cancer therapy: Drug and gene delivery, phototherapy, immunotherapy, and vaccine development.
Sadeghi MS, Sangrizeh FH, Jahani N, Abedin MS, Chaleshgari S, Ardakan AK, Baeelashaki R, Ranjbarpazuki G, Rahmanian P, Zandieh MA, Nabavi N, Aref AR, Salimimoghadam S, Rashidi M, Rezaee A, Hushmandi K. Sadeghi MS, et al. Environ Res. 2023 Nov 15;237(Pt 2):117027. doi: 10.1016/j.envres.2023.117027. Epub 2023 Sep 1. Environ Res. 2023. PMID: 37659647 Review.
GO nanomaterials have the potential to trigger both cellular and innate immunity, making them promising contenders for vaccine development. Additionally, types of GO nanoparticles that respond to specific stimuli have been applied in cancer eradication, as well as for the …
GO nanomaterials have the potential to trigger both cellular and innate immunity, making them promising contenders for vaccine develo …
Chitosan-functionalized graphene oxide as adjuvant in HEV P239 vaccine.
Bai Q, Wang Z, An Y, Tian J, Li Z, Yang Y, Dong Y, Chen M, Liu T. Bai Q, et al. Vaccine. 2022 Dec 12;40(52):7613-7621. doi: 10.1016/j.vaccine.2022.11.005. Epub 2022 Nov 9. Vaccine. 2022. PMID: 36371365
Searching appropriate adjuvants for vaccine is a potent method to intense the immune efficacy. In the present study, we developed a novel Hepatitis E virus (HEV) vaccine by utilizing chitosan modified nano-graphene oxide (GO-CS) as an adjuvant to suppo …
Searching appropriate adjuvants for vaccine is a potent method to intense the immune efficacy. In the present study, we developed a n …
Encountering and Wrestling: Neutrophils Recognize and Defensively Degrade Graphene Oxide.
Huang S, Li S, Liu Y, Ghalandari B, Hao L, Huang C, Su W, Ke Y, Cui D, Zhi X, Ding X. Huang S, et al. Adv Healthc Mater. 2022 Apr;11(8):e2102439. doi: 10.1002/adhm.202102439. Epub 2021 Dec 10. Adv Healthc Mater. 2022. PMID: 34859964
The boosting exploitation of graphene oxide (GO) increases exposure risk to human beings. However, as primary defender in the first immune line, neutrophils' mechanism of defensive behavior toward GO remains unclear. ...This study provides fundamental evidence and p …
The boosting exploitation of graphene oxide (GO) increases exposure risk to human beings. However, as primary defender in the …
Graphene oxide in the fight against viruses: from biosensing and antiviral action to protective materials and vaccine delivery.
Kashfia N, Islam MS, Sekine Y, Hayami S. Kashfia N, et al. J Mater Chem B. 2026 Feb 4;14(5):1461-1473. doi: 10.1039/d5tb02528a. J Mater Chem B. 2026. PMID: 41532724 Review.
Graphene oxide (GO) has evolved from a laboratory curiosity into a practical and multifunctional material against viral threats. ...By connecting molecular mechanisms with real-world implementations, this review underscores how GO can serve as a platform technology …
Graphene oxide (GO) has evolved from a laboratory curiosity into a practical and multifunctional material against viral threat …
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine.
Huang S, Li Y, Zhang S, Chen Y, Su W, Sanchez DJ, Mai JDH, Zhi X, Chen H, Ding X. Huang S, et al. J Control Release. 2024 Jan;365:716-728. doi: 10.1016/j.jconrel.2023.11.047. Epub 2023 Dec 11. J Control Release. 2024. PMID: 38036004
Herein, self-assembled nanoparticles based on graphene oxide quantum dots with components of carnosine, resiquimod and Zn(2+) ions, namely ZnGC-R, are designed as a new adjuvant for influenza vaccine. ...Besides, ZnGC-R elicited 2.53-fold higher hemagglutinat …
Herein, self-assembled nanoparticles based on graphene oxide quantum dots with components of carnosine, resiquimod and Zn(2+) …
Preparation of graphene oxide-stabilized Pickering emulsion adjuvant for Pgp3 recombinant vaccine and enhanced immunoprotection against Chlamydia Trachomatis infection.
Zhao L, Shu M, Chen H, Shi K, Li Z. Zhao L, et al. Front Immunol. 2023 Apr 18;14:1148253. doi: 10.3389/fimmu.2023.1148253. eCollection 2023. Front Immunol. 2023. PMID: 37143655 Free PMC article.
BACKGROUND: Traditional emulsion adjuvants are limited in clinical application because of their surfactant dependence. Graphene oxide (GO) has unique amphiphilic properties and therefore has potential to be used as a surfactant substitute to stabilize Pickering emul …
BACKGROUND: Traditional emulsion adjuvants are limited in clinical application because of their surfactant dependence. Graphene ox …
Graphene oxide-ellagic acid nanocomposite as effective anticancer and antimicrobial agent.
Hussein-Al-Ali SH, Abudoleh SM, Hussein MZ, Bullo S, Palanisamy A. Hussein-Al-Ali SH, et al. IET Nanobiotechnol. 2021 Feb;15(1):79-89. doi: 10.1049/nbt2.12009. Epub 2021 Feb 2. IET Nanobiotechnol. 2021. PMID: 34694731 Free PMC article.
In this study, ellagic acid (ELA), a skin anticancer drug, is capped on the surface(s) of functionalised graphene oxide (GO) nano-sheets through electrostatic and pi-pi staking interactions. The prepared ELA-GO nanocomposite have been thoroughly characterised by usi …
In this study, ellagic acid (ELA), a skin anticancer drug, is capped on the surface(s) of functionalised graphene oxide (GO) n …
A dicoumarol-graphene oxide quantum dot polymer inhibits porcine reproductive and respiratory syndrome virus through the JAK-STAT signaling pathway.
Li Z, Wang J, Wang S, Zhao W, Hou X, Wang J, Dong H, Zhou S, Gao Y, Yao W, Li H, Liu X. Li Z, et al. Front Microbiol. 2024 Jun 19;15:1417404. doi: 10.3389/fmicb.2024.1417404. eCollection 2024. Front Microbiol. 2024. PMID: 38962129 Free PMC article.
INTRODUCTION: Porcine reproductive and respiratory syndrome virus (PRRSV) causes substantial economic losses in the global swine industry. The current vaccine options offer limited protection against PRRSV transmission, and there are no effective commercial antivirals avai …
INTRODUCTION: Porcine reproductive and respiratory syndrome virus (PRRSV) causes substantial economic losses in the global swine industry. T …
85 results