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Page 1
Graphene oxide as novel vaccine adjuvant.
Vakili B, Karami-Darehnaranji M, Mirzaei E, Hosseini F, Nezafat N. Vakili B, et al. Int Immunopharmacol. 2023 Dec;125(Pt A):111062. doi: 10.1016/j.intimp.2023.111062. Epub 2023 Oct 23. Int Immunopharmacol. 2023. PMID: 37866317 Review.
To improve antigen immunogenicity and promote long-lasting immunity, vaccine formulations have been appropriately supplemented with adjuvants. Graphene has been found to enhance the presentation of antigens to CD8+ T cells, as well as stimulating innate immune responses an …
To improve antigen immunogenicity and promote long-lasting immunity, vaccine formulations have been appropriately supplemented with a …
Recent progress of graphene oxide as a potential vaccine carrier and adjuvant.
Cao W, He L, Cao W, Huang X, Jia K, Dai J. Cao W, et al. Acta Biomater. 2020 Aug;112:14-28. doi: 10.1016/j.actbio.2020.06.009. Epub 2020 Jun 10. Acta Biomater. 2020. PMID: 32531395 Review.
Our work describes the surface modification of graphene oxide and for the first time summarizes that functionalized graphene oxide serves as a vaccine carrier and shows significant adjuvant activity in activating cellular and humoral immunity. I …
Our work describes the surface modification of graphene oxide and for the first time summarizes that functionalized graphen …
Chitosan-functionalized graphene oxide as adjuvant in HEV P239 vaccine.
Bai Q, Wang Z, An Y, Tian J, Li Z, Yang Y, Dong Y, Chen M, Liu T. Bai Q, et al. Vaccine. 2022 Dec 12;40(52):7613-7621. doi: 10.1016/j.vaccine.2022.11.005. Epub 2022 Nov 9. Vaccine. 2022. PMID: 36371365
Searching appropriate adjuvants for vaccine is a potent method to intense the immune efficacy. In the present study, we developed a novel Hepatitis E virus (HEV) vaccine by utilizing chitosan modified nano-graphene oxide (GO-CS) as an adjuvant to suppo …
Searching appropriate adjuvants for vaccine is a potent method to intense the immune efficacy. In the present study, we developed a n …
Graphene oxide nanoarchitectures in cancer therapy: Drug and gene delivery, phototherapy, immunotherapy, and vaccine development.
Sadeghi MS, Sangrizeh FH, Jahani N, Abedin MS, Chaleshgari S, Ardakan AK, Baeelashaki R, Ranjbarpazuki G, Rahmanian P, Zandieh MA, Nabavi N, Aref AR, Salimimoghadam S, Rashidi M, Rezaee A, Hushmandi K. Sadeghi MS, et al. Environ Res. 2023 Nov 15;237(Pt 2):117027. doi: 10.1016/j.envres.2023.117027. Epub 2023 Sep 1. Environ Res. 2023. PMID: 37659647 Review.
GO nanomaterials have the potential to trigger both cellular and innate immunity, making them promising contenders for vaccine development. Additionally, types of GO nanoparticles that respond to specific stimuli have been applied in cancer eradication, as well as for the …
GO nanomaterials have the potential to trigger both cellular and innate immunity, making them promising contenders for vaccine develo …
Preparation of graphene oxide-stabilized Pickering emulsion adjuvant for Pgp3 recombinant vaccine and enhanced immunoprotection against Chlamydia Trachomatis infection.
Zhao L, Shu M, Chen H, Shi K, Li Z. Zhao L, et al. Front Immunol. 2023 Apr 18;14:1148253. doi: 10.3389/fimmu.2023.1148253. eCollection 2023. Front Immunol. 2023. PMID: 37143655 Free PMC article.
BACKGROUND: Traditional emulsion adjuvants are limited in clinical application because of their surfactant dependence. Graphene oxide (GO) has unique amphiphilic properties and therefore has potential to be used as a surfactant substitute to stabilize Pickering emul …
BACKGROUND: Traditional emulsion adjuvants are limited in clinical application because of their surfactant dependence. Graphene ox …
Functionalized graphene oxide serves as a novel vaccine nano-adjuvant for robust stimulation of cellular immunity.
Xu L, Xiang J, Liu Y, Xu J, Luo Y, Feng L, Liu Z, Peng R. Xu L, et al. Nanoscale. 2016 Feb 14;8(6):3785-95. doi: 10.1039/c5nr09208f. Epub 2016 Jan 27. Nanoscale. 2016. PMID: 26814441
In this study, we carefully engineered graphene oxide (GO) as a vaccine adjuvant for immunotherapy using urease B (Ure B) as the model antigen. ...These two advantages enable GO-PEG-PEI to serve as a novel vaccine adjuvant. In the subsequent in vivo ex …
In this study, we carefully engineered graphene oxide (GO) as a vaccine adjuvant for immunotherapy using urease B (Ure …
Novel use of graphene oxide quantum dots in a pickering emulsion as a Chlamydia trachomatis vaccine adjuvant.
Zhao L, Shu M, Shi K, Tang S, Li Z. Zhao L, et al. Int Immunopharmacol. 2023 May;118:110035. doi: 10.1016/j.intimp.2023.110035. Epub 2023 Mar 21. Int Immunopharmacol. 2023. PMID: 36958212
Graphene oxide quantum dots (GOQDs), which are graphene-based nanoparticles, are potential surfactant substitutes for stabilizing Pickering emulsions, due to their high surface area, biodegradability, and reasonable biocompatibility. ...This study provides evidence …
Graphene oxide quantum dots (GOQDs), which are graphene-based nanoparticles, are potential surfactant substitutes for stabiliz …
Lentinan-functionalized graphene oxide hydrogel as a sustained antigen delivery system for vaccines.
Jiao L, Wang Z, Song Z, Zhang T, Yu L, Yu R, Gao Q, Peng S, Jin H, Wang D, Liu Z. Jiao L, et al. Int J Biol Macromol. 2023 Dec 31;253(Pt 1):126629. doi: 10.1016/j.ijbiomac.2023.126629. Epub 2023 Aug 30. Int J Biol Macromol. 2023. PMID: 37657564
Meanwhile, graphene oxide (GO) has garnered significant attention due to its good biosafety, excellent surface area and easy modification. ...Collectively, these results demonstrate the adjuvant potential of the lentinan-functionalized graphene oxide h …
Meanwhile, graphene oxide (GO) has garnered significant attention due to its good biosafety, excellent surface area and easy m …
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine.
Huang S, Li Y, Zhang S, Chen Y, Su W, Sanchez DJ, Mai JDH, Zhi X, Chen H, Ding X. Huang S, et al. J Control Release. 2024 Jan;365:716-728. doi: 10.1016/j.jconrel.2023.11.047. Epub 2023 Dec 11. J Control Release. 2024. PMID: 38036004
Herein, self-assembled nanoparticles based on graphene oxide quantum dots with components of carnosine, resiquimod and Zn(2+) ions, namely ZnGC-R, are designed as a new adjuvant for influenza vaccine. ...Besides, ZnGC-R elicited 2.53-fold higher hemagglutinat …
Herein, self-assembled nanoparticles based on graphene oxide quantum dots with components of carnosine, resiquimod and Zn(2+) …
Chitosan-Functionalized Graphene Oxide as a Potential Immunoadjuvant.
Yan T, Zhang H, Huang D, Feng S, Fujita M, Gao XD. Yan T, et al. Nanomaterials (Basel). 2017 Mar 8;7(3):59. doi: 10.3390/nano7030059. Nanomaterials (Basel). 2017. PMID: 28336893 Free PMC article.
The application of graphene oxide (GO) as a potential vaccine adjuvant has recently attracted considerable attention. ...GO-CS exhibits strong potential as a safe nanoadjuvant for vaccines and immunotherapy....
The application of graphene oxide (GO) as a potential vaccine adjuvant has recently attracted considerable attention. . …
78 results