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Year Number of Results
1977 1
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2013 5
2014 5
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2022 27
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131 results

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Page 1
Recent progress of graphene oxide as a potential vaccine carrier and adjuvant.
Cao W, He L, Cao W, Huang X, Jia K, Dai J. Cao W, et al. Acta Biomater. 2020 Aug;112:14-28. doi: 10.1016/j.actbio.2020.06.009. Epub 2020 Jun 10. Acta Biomater. 2020. PMID: 32531395 Review.
Our work describes the surface modification of graphene oxide and for the first time summarizes that functionalized graphene oxide serves as a vaccine carrier and shows significant adjuvant activity in activating cellular and humoral immunity. In the future, …
Our work describes the surface modification of graphene oxide and for the first time summarizes that functionalized graphene o …
Chitosan-functionalized graphene oxide as adjuvant in HEV P239 vaccine.
Bai Q, Wang Z, An Y, Tian J, Li Z, Yang Y, Dong Y, Chen M, Liu T. Bai Q, et al. Vaccine. 2022 Dec 12;40(52):7613-7621. doi: 10.1016/j.vaccine.2022.11.005. Epub 2022 Nov 9. Vaccine. 2022. PMID: 36371365
Searching appropriate adjuvants for vaccine is a potent method to intense the immune efficacy. In the present study, we developed a novel Hepatitis E virus (HEV) vaccine by utilizing chitosan modified nano-graphene oxide (GO-CS) as an adjuvant to support HEV …
Searching appropriate adjuvants for vaccine is a potent method to intense the immune efficacy. In the present study, we developed a n …
The Spike of SARS-CoV-2: Uniqueness and Applications.
Kumavath R, Barh D, Andrade BS, Imchen M, Aburjaile FF, Ch A, Rodrigues DLN, Tiwari S, Alzahrani KJ, Góes-Neto A, Weener ME, Ghosh P, Azevedo V. Kumavath R, et al. Front Immunol. 2021 Jul 8;12:663912. doi: 10.3389/fimmu.2021.663912. eCollection 2021. Front Immunol. 2021. PMID: 34305894 Free PMC article. Review.
Based on this outline, we have reviewed the structure, uniqueness, and origin of the S protein of SARS-CoV-2. Furthermore, the interactions of the Spike protein with host and its implications in COVID-19 pathogenesis, as well as drug and vaccine development, are dis …
Based on this outline, we have reviewed the structure, uniqueness, and origin of the S protein of SARS-CoV-2. Furthermore, the intera …
Engineered Nanoparticles for Cancer Vaccination and Immunotherapy.
Aikins ME, Xu C, Moon JJ. Aikins ME, et al. Acc Chem Res. 2020 Oct 20;53(10):2094-2105. doi: 10.1021/acs.accounts.0c00456. Epub 2020 Oct 5. Acc Chem Res. 2020. PMID: 33017150 Free PMC article.
Unfortunately, cancer is characterized by genetic alterations in the host's cells, leading to uncontrolled cellular proliferation and evasion of immune surveillance. Cancer immunotherapy aims to educate the host's immune system to not only recognize but also attack …
Unfortunately, cancer is characterized by genetic alterations in the host's cells, leading to uncontrolled cellular proliferation and …
In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy.
Yin Y, Li X, Ma H, Zhang J, Yu D, Zhao R, Yu S, Nie G, Wang H. Yin Y, et al. Nano Lett. 2021 Mar 10;21(5):2224-2231. doi: 10.1021/acs.nanolett.0c05039. Epub 2021 Feb 17. Nano Lett. 2021. PMID: 33594887
Messenger RNA (mRNA) vaccine is a promising candidate in cancer immunotherapy as it can encode tumor-associated antigens with an excellent safety profile. Unfortunately, the inherent instability of RNA and translational efficiency are major limitations of RNA vaccine
Messenger RNA (mRNA) vaccine is a promising candidate in cancer immunotherapy as it can encode tumor-associated antigens with an exce …
Functionalized graphene oxide serves as a novel vaccine nano-adjuvant for robust stimulation of cellular immunity.
Xu L, Xiang J, Liu Y, Xu J, Luo Y, Feng L, Liu Z, Peng R. Xu L, et al. Nanoscale. 2016 Feb 14;8(6):3785-95. doi: 10.1039/c5nr09208f. Epub 2016 Jan 27. Nanoscale. 2016. PMID: 26814441
Benefiting from their unique physicochemical properties, graphene derivatives have attracted great attention in biomedicine. In this study, we carefully engineered graphene oxide (GO) as a vaccine adjuvant for immunotherapy using urease B (Ure B) as the model …
Benefiting from their unique physicochemical properties, graphene derivatives have attracted great attention in biomedicine. In this …
Potential of graphene-based materials to combat COVID-19: properties, perspectives, and prospects.
Srivastava AK, Dwivedi N, Dhand C, Khan R, Sathish N, Gupta MK, Kumar R, Kumar S. Srivastava AK, et al. Mater Today Chem. 2020 Dec;18:100385. doi: 10.1016/j.mtchem.2020.100385. Epub 2020 Oct 21. Mater Today Chem. 2020. PMID: 33106780 Free PMC article. Review.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new virus in the coronavirus family that causes coronavirus disease (COVID-19), emerges as a big threat to the human race. To date, there is no medicine and vaccine available for COVID-19 treatment. While the …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new virus in the coronavirus family that causes coronavirus disease (COVID-1 …
Indirect voltammetric determination of thiomersal in influenza vaccine using photo-degradation and graphene quantum dots modified glassy carbon electrode.
Pedrozo-Penafiel MJ, Miranda-Andrades JR, Gutierrez-Beleño LM, Larrudé DG, Aucelio RQ. Pedrozo-Penafiel MJ, et al. Talanta. 2020 Aug 1;215:120938. doi: 10.1016/j.talanta.2020.120938. Epub 2020 Mar 19. Talanta. 2020. PMID: 32312472 Free article.
It is widely used in topical pharmaceutical preparations and as preservative in vaccines and cosmetics. In this work, an electro-analytical method for thiomersal was developed using graphene quantum dots (GQDs) as a surface modifier of a glassy carbon electrode. ... …
It is widely used in topical pharmaceutical preparations and as preservative in vaccines and cosmetics. In this work, an electro-anal …
Nano dimensions/adjuvants in COVID-19 vaccines.
Alphandéry E. Alphandéry E. J Mater Chem B. 2022 Mar 9;10(10):1520-1552. doi: 10.1039/d1tb02408f. J Mater Chem B. 2022. PMID: 35166754 Review.
A favorable outcome of the COVID-19 crisis might be achieved with massive vaccination. The proposed vaccines contain several different vaccine active principles (VAP), such as inactivated virus, antigen, mRNA, and DNA, which are associated with either standar …
A favorable outcome of the COVID-19 crisis might be achieved with massive vaccination. The proposed vaccines contain several d …
Graphene Sheets with Defined Dual Functionalities for the Strong SARS-CoV-2 Interactions.
Donskyi IS, Nie C, Ludwig K, Trimpert J, Ahmed R, Quaas E, Achazi K, Radnik J, Adeli M, Haag R, Osterrieder K. Donskyi IS, et al. Small. 2021 Mar;17(11):e2007091. doi: 10.1002/smll.202007091. Epub 2021 Feb 2. Small. 2021. PMID: 33533178 Free PMC article.
In this work, inhibition of SARS-CoV-2 by graphene platforms with precise dual sulfate/alkyl functionalities is investigated. ...Graphene derivatives with long alkyl chains (>C9) inhibit coronavirus replication by virtue of disrupting viral envelope. ...
In this work, inhibition of SARS-CoV-2 by graphene platforms with precise dual sulfate/alkyl functionalities is investigated. ...G
131 results