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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1975 2
1976 1
1980 4
1981 1
1982 8
1983 4
1984 3
1985 1
1986 3
1987 3
1988 2
1989 5
1990 11
1991 5
1992 9
1993 4
1994 13
1995 6
1996 8
1997 10
1998 10
1999 12
2000 9
2001 11
2002 12
2003 9
2004 11
2005 15
2006 24
2007 24
2008 12
2009 18
2010 13
2011 29
2012 24
2013 12
2014 16
2015 16
2016 23
2017 14
2018 8
2019 6
2020 14
2021 15
2022 8
2023 10
2024 5
2025 7
2026 2

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447 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Pharmacotherapy and immunotherapy of allergic rhinitis induced by house dust mite, grass, and birch pollen allergens: a meta-analysis of randomized clinical trials.
Marko M, Pawliczak R. Marko M, et al. Expert Rev Respir Med. 2023 Jul-Dec;17(7):607-621. doi: 10.1080/17476348.2023.2241364. Epub 2023 Jul 28. Expert Rev Respir Med. 2023. PMID: 37489655 Review.
The authors focused on the division into selected AR's triggers: house dust mites (HDMs), grass pollen, and birch pollen. METHODS: For each drug and allergen class, a meta-analysis of the efficacy and adverse events (AEs) was performed. ...The best tot …
The authors focused on the division into selected AR's triggers: house dust mites (HDMs), grass pollen, and birch pollen …
Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response.
Golebski K, Layhadi JA, Sahiner U, Steveling-Klein EH, Lenormand MM, Li RCY, Bal SM, Heesters BA, Vilà-Nadal G, Hunewald O, Montamat G, HeFeng FQ, Ollert M, Fedina O, Lao-Araya M, Vijverberg SJH, Maitland-van der Zee AH, van Drunen CM, Fokkens WJ, Durham SR, Spits H, Shamji MH. Golebski K, et al. Immunity. 2021 Feb 9;54(2):291-307.e7. doi: 10.1016/j.immuni.2020.12.013. Epub 2021 Jan 14. Immunity. 2021. PMID: 33450188 Free article. Clinical Trial.
The role of innate immune cells in allergen immunotherapy that confers immune tolerance to the sensitizing allergen is unclear. ...IL-10(+) KLRG1(+) ILC2s were lower in patients with grass-pollen allergy when compared to healthy subjects. In a prospect …
The role of innate immune cells in allergen immunotherapy that confers immune tolerance to the sensitizing allergen is unclear …
Intralymphatic immunotherapy with one or two allergens renders similar clinical response in patients with allergic rhinitis due to birch and grass pollen.
Ahlbeck L, Ahlberg E, Björkander J, Aldén C, Papapavlou G, Palmberg L, Nyström U, Retsas P, Nordenfelt P, Togö T, Johansen P, Rolander B, Duchén K, Jenmalm MC. Ahlbeck L, et al. Clin Exp Allergy. 2022 Jun;52(6):747-759. doi: 10.1111/cea.14138. Epub 2022 Apr 1. Clin Exp Allergy. 2022. PMID: 35332591 Free PMC article. Clinical Trial.
RESULTS: The three groups reported fewer symptoms, lower use of medication and improved quality of life during the birch and grass pollen seasons each year after treatment at an almost similar rate independently of treatment with one or two allergens. ...CONC …
RESULTS: The three groups reported fewer symptoms, lower use of medication and improved quality of life during the birch and grass …
Efficacy and safety of sublingual versus subcutaneous immunotherapy in children with allergic rhinitis: a systematic review and meta-analysis.
Yang J, Lei S. Yang J, et al. Front Immunol. 2023 Dec 15;14:1274241. doi: 10.3389/fimmu.2023.1274241. eCollection 2023. Front Immunol. 2023. PMID: 38162647 Free PMC article.

Subgroup analysis was further conducted in terms of study design [randomized controlled trials (RCTs), cohort studies], allergen [house dust mites (HDMs), grass pollen], treatment duration ( 24, 12-23 or < 12 months), allergen immunotherapy (AIT) mo

…
Subgroup analysis was further conducted in terms of study design [randomized controlled trials (RCTs), cohort studies], allergen [hou …
Grass pollen allergoids conjugated with mannan for subcutaneous and sublingual immunotherapy: a dose-finding study.
Ojeda P, Barjau MC, Subiza J, Moreno A, Ojeda I, Solano E, Alonso A, Caballero R, Del Pozo S, Gómez-Perosanz M, Sánchez-Trincado JL, Benito-Villalvilla C, Angelina A, Soria I, Reche PA, Palomares O, Subiza JL, Casanovas M. Ojeda P, et al. Front Immunol. 2024 Jun 26;15:1431351. doi: 10.3389/fimmu.2024.1431351. eCollection 2024. Front Immunol. 2024. PMID: 38989287 Free PMC article. Clinical Trial.
BACKGROUND: Polymerized allergoids conjugated with mannan represent a novel approach of allergen immunotherapy targeting dendritic cells. In this study, we aimed to determine the optimal dose of mannan-allergoid conjugates derived from grass pollen (Phleum pr …
BACKGROUND: Polymerized allergoids conjugated with mannan represent a novel approach of allergen immunotherapy targeting dendritic ce …
Immunotherapy with grass pollen major allergens.
Osterballe O. Osterballe O. Allergy. 1982 Aug;37(6):379-88. doi: 10.1111/j.1398-9995.1982.tb02316.x. Allergy. 1982. PMID: 7137533 Clinical Trial.
Perennial hyposensitization with a partially purified timothy extract resulted in a statistically significantly higher degree of clinical protection than treatment with the two timothy major allergens (Nos. 19 and 25) and protected better from the second--than during the f …
Perennial hyposensitization with a partially purified timothy extract resulted in a statistically significantly higher degree of clinical pr …
Effect of immunostimulation with bacterial lysate on the clinical course of allergic rhinitis and the level of gammadeltaT, iNKT and cytotoxic T cells in children sensitized to grass pollen allergens: A randomized controlled trial.
Janeczek K, Kowalska W, Zarobkiewicz M, Suszczyk D, Mikołajczyk M, Markut-Miotła E, Morawska-Michalska I, Bakiera A, Tomczak A, Kaczyńska A, Emeryk A, Roliński J, Piotrowska-Weryszko K. Janeczek K, et al. Front Immunol. 2023 Jan 17;14:1073788. doi: 10.3389/fimmu.2023.1073788. eCollection 2023. Front Immunol. 2023. PMID: 36733480 Free PMC article. Clinical Trial.
OBJECTIVES: The objectives of this study were to evaluate the efficacy of polyvalent mechanical bacterial lysate (PMBL) therapy in improving the clinical course of grass pollen-induced AR (seasonal AR, SAR) in children and its effect on changes in the blood level of …
OBJECTIVES: The objectives of this study were to evaluate the efficacy of polyvalent mechanical bacterial lysate (PMBL) therapy in improving …
Is exposure to pollen a risk factor for moderate and severe asthma exacerbations?
Annesi-Maesano I, Cecchi L, Biagioni B, Chung KF, Clot B, Collaud Coen M, D'Amato G, Damialis A, Dominguez-Ortega J, Galàn C, Gilles S, Holgate S, Jeebhay M, Kazadzis S, Papadopoulos NG, Quirce S, Sastre J, Tummon F, Traidl-Hoffmann C, Walusiak-Skorupa J, Alonso-Coello P, Canelo-Aybar C, Cantero-Fortiz Y, Rigau D, Salazar J, Verdugo-Paiva F, Jutel M, Akdis CA, Agache I. Annesi-Maesano I, et al. Allergy. 2023 Aug;78(8):2121-2147. doi: 10.1111/all.15724. Epub 2023 Apr 10. Allergy. 2023. PMID: 36961370 Review.
The strongest associations were found between asthma attacks, asthma-related ED admissions or hospitalizations, and an increase in grass pollen concentration in the previous 2-day overall in children aged less than 18 years of age. ...Rare data show that among subje …
The strongest associations were found between asthma attacks, asthma-related ED admissions or hospitalizations, and an increase in grass …
Allergen-specific immunotherapy with recombinant grass pollen allergens.
Jutel M, Jaeger L, Suck R, Meyer H, Fiebig H, Cromwell O. Jutel M, et al. J Allergy Clin Immunol. 2005 Sep;116(3):608-13. doi: 10.1016/j.jaci.2005.06.004. J Allergy Clin Immunol. 2005. PMID: 16159631 Clinical Trial.
OBJECTIVE: To determine the effectiveness of a mixture of 5 recombinant grass pollen allergens in reducing symptoms and need for symptomatic medication in patients allergic to grass pollen. ...All treated subjects developed strong allergen …
OBJECTIVE: To determine the effectiveness of a mixture of 5 recombinant grass pollen allergens in reducing symptoms and …
Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy.
Altman MC, Segnitz RM, Larson D, Jayavelu ND, Smith MT, Patel S, Scadding GW, Qin T, Sanda S, Steveling E, Eifan AO, Penagos M, Jacobson MR, Parkin RV, Shamji MH, Togias A, Durham SR. Altman MC, et al. J Allergy Clin Immunol. 2023 Nov;152(5):1247-1260. doi: 10.1016/j.jaci.2023.06.025. Epub 2023 Jul 15. J Allergy Clin Immunol. 2023. PMID: 37460024 Free PMC article. Clinical Trial.
BACKGROUND: Allergen immunotherapy (AIT) is a well-established disease-modifying therapy for allergic rhinitis, yet the fundamental mechanisms underlying its clinical effect remain inadequately understood. ...METHODS: We used longitudinal transcriptomic profiling of nasal …
BACKGROUND: Allergen immunotherapy (AIT) is a well-established disease-modifying therapy for allergic rhinitis, yet the fundamental m …
447 results