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Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review.
Rady I, Bloch MB, Chamcheu RN, Banang Mbeumi S, Anwar MR, Mohamed H, Babatunde AS, Kuiate JR, Noubissi FK, El Sayed KA, Whitfield GK, Chamcheu JC. Rady I, et al. Oxid Med Cell Longev. 2018 Jul 30;2018:1826170. doi: 10.1155/2018/1826170. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30151067 Free PMC article. Review.
Graviola (Annona muricata) is a small deciduous tropical evergreen fruit tree, belonging to the Annonaceae family, and is widely grown and distributed in tropical and subtropical regions around the world. ...Over 212 phytochemical ingredients have been reported in gravi …
Graviola (Annona muricata) is a small deciduous tropical evergreen fruit tree, belonging to the Annonaceae family, and is widely grow …
Emerging therapeutic potential of graviola and its constituents in cancers.
Qazi AK, Siddiqui JA, Jahan R, Chaudhary S, Walker LA, Sayed Z, Jones DT, Batra SK, Macha MA. Qazi AK, et al. Carcinogenesis. 2018 Apr 5;39(4):522-533. doi: 10.1093/carcin/bgy024. Carcinogenesis. 2018. PMID: 29462271 Free PMC article. Review.
Among the best known of these is Annona muricata, also known as soursop, graviola or guanabana. Extracts from the fruit, bark, seeds, roots and leaves of graviola, along with several other Annonaceous species, have been extensively investigated for anticancer, anti- …
Among the best known of these is Annona muricata, also known as soursop, graviola or guanabana. Extracts from the fruit, bark, seeds, …
Graviola mitigates acetic acid-induced ulcerative colitis in rats: insight on apoptosis and Wnt/Hh signaling crosstalk.
Helal MG, Abd Elhameed AG. Helal MG, et al. Environ Sci Pollut Res Int. 2021 Jun;28(23):29615-29628. doi: 10.1007/s11356-021-12716-0. Epub 2021 Feb 9. Environ Sci Pollut Res Int. 2021. PMID: 33559079
Twenty-eight mature male rats were divided into four groups, Sham, Colitis, Colitis/Sulfa, and Colitis/Graviola, and were treated orally with either saline, saline, sulfasalazine (100 mg/kg/day), or graviola (100 mg/kg/day), respectively, for 7 days. ...Macroscopic …
Twenty-eight mature male rats were divided into four groups, Sham, Colitis, Colitis/Sulfa, and Colitis/Graviola, and were treated ora …
The Antioxidant Potential of Graviola and Its Potential Medicinal Application.
Olas B. Olas B. Nutrients. 2023 Jan 12;15(2):402. doi: 10.3390/nu15020402. Nutrients. 2023. PMID: 36678273 Free PMC article. Review.
Graviola (Annunona muricata L.), a plant growing in tropical regions, has many names and a range of ethnomedicinal uses. ...However, few findings have been obtained from clinical trials, and few in vitro and animal studies suggest that graviola preparations have ant …
Graviola (Annunona muricata L.), a plant growing in tropical regions, has many names and a range of ethnomedicinal uses. ...However, …
The graviola impact on human astroglioma cells: functional significance of MUDENG.
Gopal J, Lee YM, Shin J, Muthu M, Jung S, Jeong S, Oh J, Oh JW. Gopal J, et al. RSC Adv. 2019 Mar 18;9(16):8935-8942. doi: 10.1039/c8ra10039j. eCollection 2019 Mar 15. RSC Adv. 2019. PMID: 35517667 Free PMC article.
Graviola (Annona muricate) is a coveted tropical plant that has been found to be effective against many human cancers. ...Interestingly, graviola leaf extract-Korea (GLE-K), graviola leaf extract-Africa (GLE-A) and graviola fruit extract-Africa (GFE-A) …
Graviola (Annona muricate) is a coveted tropical plant that has been found to be effective against many human cancers. ...Interesting …
Evaluation of Annona muricata (Graviola) leaves activity against experimental trichinellosis: in vitro and in vivo studies.
El-Wakil ES, Abdelmaksoud HF, AbouShousha TS, Ghallab MMI. El-Wakil ES, et al. J Helminthol. 2021 Sep 13;95:e53. doi: 10.1017/S0022149X21000481. J Helminthol. 2021. PMID: 34515021
Our work aimed to evaluate the possible effect of Annona muricata (Graviola) leaf extract on Trichinella spiralis in in vitro and in vivo studies. ...In the in vivo study, mice were divided into five groups: GI (infected untreated), GII (prophylactically treated with Gr …
Our work aimed to evaluate the possible effect of Annona muricata (Graviola) leaf extract on Trichinella spiralis in in vitro and in …
Graviola attenuates DMBA-induced breast cancer possibly through augmenting apoptosis and antioxidant pathway and downregulating estrogen receptors.
Zeweil MM, Sadek KM, Taha NM, El-Sayed Y, Menshawy S. Zeweil MM, et al. Environ Sci Pollut Res Int. 2019 May;26(15):15209-15217. doi: 10.1007/s11356-019-04920-w. Epub 2019 Mar 29. Environ Sci Pollut Res Int. 2019. PMID: 30924043
Breast cancer is a global public health problem where it is the second most prevalent cancer. Historical cancer treatment with graviola has been reported. This study aimed to investigate the protective effects of graviola on 7,12-dimethylbenz[a]anthracene (DMBA)-ind …
Breast cancer is a global public health problem where it is the second most prevalent cancer. Historical cancer treatment with graviola …
Anticancer and Apoptogenic Effect of Graviola and Low-Dose Radiation in Tumor Xenograft in Mice.
El Tawiil GA, Noaman EA, Askar MA, El Fatih NM, Mohamed HE. El Tawiil GA, et al. Integr Cancer Ther. 2020 Jan-Dec;19:1534735419900930. doi: 10.1177/1534735419900930. Integr Cancer Ther. 2020. PMID: 32493124 Free PMC article.

Results: The result obtained showed a significant decrease (P < .05) of tumor size in 28 graviola-treated EST-bearing mice group (EG) or graviola-treated and irradiated EST-30-bearing mice (EGR) groups versus the EST group. ...The combined treatment of graviol

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Results: The result obtained showed a significant decrease (P < .05) of tumor size in 28 graviola-treated EST-bearing mice group (

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Ameliorative Effect of Graviola (Annona muricata) on Mono Sodium Glutamate-Induced Hepatic Injury in Rats: Antioxidant, Apoptotic, Anti-inflammatory, Lipogenesis Markers, and Histopathological Studies.
Shukry M, El-Shehawi AM, El-Kholy WM, Elsisy RA, Hamoda HS, Tohamy HG, Abumandour MM, Farrag FA. Shukry M, et al. Animals (Basel). 2020 Oct 30;10(11):1996. doi: 10.3390/ani10111996. Animals (Basel). 2020. PMID: 33143024 Free PMC article.
Fifty Wistar rats were randomly allocated into five groups: control (received normal saline), Graviola (received 200 mg/kg body weight), MSG (received 2.4 gm MSG/kg, 15% of Lethal dose (LD(50)) of MSG), Graviola + monosodium glutamate (MSG + GE; received GE, 200 mg/ …
Fifty Wistar rats were randomly allocated into five groups: control (received normal saline), Graviola (received 200 mg/kg body weigh …
Efficacy of Annona muricata (graviola) in experimental spinal cord injury: biochemical and histopathological analysis.
Keskin E, Elmas Ö, Keser Şahin HH, Güven B. Keskin E, et al. Ulus Travma Acil Cerrahi Derg. 2022 Mar;28(3):233-241. doi: 10.14744/tjtes.2021.70728. Ulus Travma Acil Cerrahi Derg. 2022. PMID: 35485570 Free article. English.
BACKGROUND: Annona muricata (AM) (graviola) is a plant that grows in tropical regions and is thought to be good for many diseases by local people. ...
BACKGROUND: Annona muricata (AM) (graviola) is a plant that grows in tropical regions and is thought to be good for many diseases by …
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