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Page 1
Comprehensive Evaluation of Push-Pull Osmotic Pump Tablets Using Biopredictive Dissolution Tests in Advanced Modular Platform, MRI Visualizations, and Pharmacokinetic Simulations.
Danielak D, Paszkowska J, Martin L, Gimbel J, Ferrizzi D, Dobosz J, Romański M, Baran E, Kulinowski P, Winiarski M, Smoleński M, Staniszewska M, Myslitska D, Rajabi-Siahboomi A, Garbacz G. Danielak D, et al. Among authors: garbacz g. Mol Pharm. 2025 Sep 1;22(9):5576-5591. doi: 10.1021/acs.molpharmaceut.5c00612. Epub 2025 Jul 30. Mol Pharm. 2025. PMID: 40739658
Hydrophilic and Amphiphilic Macromolecules as Modulators of the Physical Stability and Bioavailability of Piribedil: A Study on Binary Mixtures and Micellar Systems.
Orszulak L, Minecka A, Bernat R, Lamrani T, Jurkiewicz K, Hachuła B, Tarnacka M, Geppert-Rybczyńska M, Zubko M, Staniszewska M, Smoleński M, Dobosz J, Garbacz G, Kamiński K, Kamińska E. Orszulak L, et al. Among authors: garbacz g. Mol Pharm. 2025 Aug 4;22(8):4708-4730. doi: 10.1021/acs.molpharmaceut.5c00276. Epub 2025 Jun 30. Mol Pharm. 2025. PMID: 40586556 Free PMC article.
Gastric stress events impact the bioavailability of a poorly soluble weak base dabigatran from pellet-filled capsules: An outcome from pharmacokinetic simulations based on biorelevant dissolution testing, machine learning, and a novel timewise first-order dissolution model.
Romański M, Staniszewska M, Myslitska D, Paszkowska J, Banach G, Polak S, Garbacz G, Danielak D. Romański M, et al. Among authors: garbacz g. Int J Pharm. 2025 Apr 15;674:125464. doi: 10.1016/j.ijpharm.2025.125464. Epub 2025 Mar 12. Int J Pharm. 2025. PMID: 40086652
More Than a Gut Feeling─A Combination of Physiologically Driven Dissolution and Pharmacokinetic Modeling as a Tool for Understanding Human Gastric Motility.
Romański M, Staniszewska M, Dobosz J, Myslitska D, Paszkowska J, Kołodziej B, Romanova S, Banach G, Garbacz G, Sarcevica I, Huh Y, Purohit V, McAllister M, Wong SM, Danielak D. Romański M, et al. Among authors: garbacz g. Mol Pharm. 2024 Aug 5;21(8):3824-3837. doi: 10.1021/acs.molpharmaceut.4c00117. Epub 2024 Jul 3. Mol Pharm. 2024. PMID: 38958668 Free PMC article.
In Vitro Simulation of the Fasted Gastric Conditions and Their Variability to Elucidate Contrasting Properties of the Marketed Dabigatran Etexilate Pellet-Filled Capsules and Loose Pellets.
Staniszewska M, Myslitska D, Romański M, Polak S, Garbacz G, Dobosz J, Smoleński M, Paszkowska J, Danielak D. Staniszewska M, et al. Among authors: garbacz g. Mol Pharm. 2024 May 6;21(5):2456-2472. doi: 10.1021/acs.molpharmaceut.4c00025. Epub 2024 Apr 3. Mol Pharm. 2024. PMID: 38568423
An extension of biorelevant fed-state dissolution tests to clinical pharmacokinetics - A study on gastrointestinal factors influencing rivaroxaban exposure and efficacy in atrial fibrillation patients.
Romański M, Giebułtowicz J, Gniazdowska E, Piotrowski R, Żuk A, Kułakowski P, Paszkowska J, Myslitska D, Sczodrok J, Garbacz G, Danielak D. Romański M, et al. Among authors: garbacz g. Int J Pharm. 2024 Jan 5;649:123626. doi: 10.1016/j.ijpharm.2023.123626. Epub 2023 Nov 23. Int J Pharm. 2024. PMID: 38000647
A Rational Approach to Predicting Immediate Release Formulation Behavior in Multiple Gastric Motility Patterns: A Combination of a Biorelevant Apparatus, Design of Experiments, and Machine Learning.
Staniszewska M, Romański M, Polak S, Garbacz G, Dobosz J, Myslitska D, Romanova S, Paszkowska J, Danielak D. Staniszewska M, et al. Among authors: garbacz g. Pharmaceutics. 2023 Jul 31;15(8):2056. doi: 10.3390/pharmaceutics15082056. Pharmaceutics. 2023. PMID: 37631270 Free PMC article.
52 results