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Year Number of Results
1872 2
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1987 1
1988 1
1991 1
1992 2
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1994 5
1995 1
1996 3
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1998 5
1999 2
2000 2
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2002 10
2003 5
2004 5
2005 17
2006 15
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2008 7
2009 5
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2018 32
2019 33
2020 29
2021 2
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Safety of Guarana Seed as a Dietary Ingredient: A Review.
Patrick M, Kim HA, Oketch-Rabah H, Marles RJ, Roe AL, Calderón AI. Patrick M, et al. J Agric Food Chem. 2019 Oct 16;67(41):11281-11287. doi: 10.1021/acs.jafc.9b03781. Epub 2019 Oct 3. J Agric Food Chem. 2019. PMID: 31539257
The seeds of the guarana plant (Paullinia cupana Kunth, family Sapindaceae) are well-known to many cultures as a stimulant, aphrodisiac, and astringent. ...Overall, guarana is generally recognized as safe as a dietary ingredient marketed for its flavor and ca …
The seeds of the guarana plant (Paullinia cupana Kunth, family Sapindaceae) are well-known to many cultures as a stimulant, ap …
Modulatory Effects of Guarana (Paullinia cupana) on Adipogenesis.
Lima NDS, Numata EP, Mesquita LMS, Dias PH, Vilegas W, Gambero A, Ribeiro ML. Lima NDS, et al. Nutrients. 2017 Jun 20;9(6):635. doi: 10.3390/nu9060635. Nutrients. 2017. PMID: 28632199 Free PMC article.
Guarana (Paullinia cupana) is a plant originated in Brazil that presents a beneficial effect on body weight control and metabolic alterations. ...Together our data demonstrate the important role of guarana as a putative therapeutic agent....
Guarana (Paullinia cupana) is a plant originated in Brazil that presents a beneficial effect on body weight control and metabo …
Guarana provides additional stimulation over caffeine alone in the planarian model.
Moustakas D, Mezzio M, Rodriguez BR, Constable MA, Mulligan ME, Voura EB. Moustakas D, et al. PLoS One. 2015 Apr 16;10(4):e0123310. doi: 10.1371/journal.pone.0123310. eCollection 2015. PLoS One. 2015. PMID: 25880065 Free PMC article.
The mix of other natural chemicals contained in guarana seeds is thought to heighten the stimulant effects of guarana over caffeine alone. Yet, despite the growing use of guarana as an additive in energy drinks, and a burgeoning market for it as a nutritional …
The mix of other natural chemicals contained in guarana seeds is thought to heighten the stimulant effects of guarana over caf …
Guarana supplementation attenuated obesity, insulin resistance, and adipokines dysregulation induced by a standardized human Western diet via brown adipose tissue activation.
Bortolin RC, Vargas AR, de Miranda Ramos V, Gasparotto J, Chaves PR, Schnorr CE, da Boit Martinello K, Silveira AK, Gomes HM, Rabelo TK, Grunwald MS, Ligabue-Braun R, Gelain DP, Moreira JCF. Bortolin RC, et al. Phytother Res. 2019 May;33(5):1394-1403. doi: 10.1002/ptr.6330. Epub 2019 Mar 13. Phytother Res. 2019. PMID: 30868680
Molecular docking suggested a direct activation of AMPK by four guarana compounds tested here. We propose that brown adipose tissue activation is one of the action mechanisms involved in guarana supplementation-induced weight loss and that direct AMPK activation may …
Molecular docking suggested a direct activation of AMPK by four guarana compounds tested here. We propose that brown adipose tissue a …
Protective effect of guarana-loaded liposomes on hemolytic activity.
Roggia I, Dalcin AJF, Ourique AF, da Cruz IBM, Ribeiro EE, Mitjans M, Vinardell MP, Gomes P. Roggia I, et al. Colloids Surf B Biointerfaces. 2020 Mar;187:110636. doi: 10.1016/j.colsurfb.2019.110636. Epub 2019 Nov 11. Colloids Surf B Biointerfaces. 2020. PMID: 31757446 Free article.
Paullinia cupana var. sorbilis (Mart.) Ducke, popularly known as guarana, is one of the most promising plants in Brazilian flora and has attracted considerable interest from the scientific community owing to its numerous therapeutic activities and less side effects. …
Paullinia cupana var. sorbilis (Mart.) Ducke, popularly known as guarana, is one of the most promising plants in Brazilian flo …
Guarana: revisiting a highly caffeinated plant from the Amazon.
Schimpl FC, da Silva JF, Gonçalves JF, Mazzafera P. Schimpl FC, et al. J Ethnopharmacol. 2013 Oct 28;150(1):14-31. doi: 10.1016/j.jep.2013.08.023. Epub 2013 Aug 24. J Ethnopharmacol. 2013. PMID: 23981847 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Guarana (Paullinia cupana Kunth var. sorbilis (Mart.) Ducke) has been traditionally consumed by indigenous communities of the Amazon region. ...However, guarana has other components and there is great interest in studies design …
ETHNOPHARMACOLOGICAL RELEVANCE: Guarana (Paullinia cupana Kunth var. sorbilis (Mart.) Ducke) has been traditionally consumed b …
Lipotoxicity-associated inflammation is prevented by guarana (Paullinia cupana) in a model of hyperlipidemia.
Ruchel JB, Bernardes VM, Braun JBS, Manzoni AG, Passos DF, Castilhos LG, Abdalla FH, de Oliveira JS, de Andrade CM, Casali EA, da Cruz IBM, Leal DBR. Ruchel JB, et al. Drug Chem Toxicol. 2019 Jun 14:1-9. doi: 10.1080/01480545.2019.1624767. Online ahead of print. Drug Chem Toxicol. 2019. PMID: 31195840
Thus, this study aims to evaluate the effect of guarana powder (Paullinia cupana) in the purine metabolism and inflammatory profile in lymphocytes and serum of rats with Poloxamer-407-induced hyperlipidemia. ...The effects of guarana were more pronounced, sug …
Thus, this study aims to evaluate the effect of guarana powder (Paullinia cupana) in the purine metabolism and inflammatory pr …
Guarana (Paullinia cupana) consumption improves hepatic and renal parameters in alloxan-induced diabetic rats.
Abboud RS, Ribeiro ICA, Pereira VA, Corrêa LBN, Boaventura GT, Chagas MA. Abboud RS, et al. Nutr Hosp. 2020 Apr 16;37(2):343-348. doi: 10.20960/nh.02759. Nutr Hosp. 2020. PMID: 31746621 Free article. English.
Objective: this study aims to evaluate the protective action of the guarana compound on the biochemical profile of alloxan-induced diabetes in rats. Method: twenty-eight male Wistar Furth rats were divided into four groups of seven animals each: the control group (CG) was …
Objective: this study aims to evaluate the protective action of the guarana compound on the biochemical profile of alloxan-induced di …
Neuroprotective Effects of Guarana (Paullinia cupana Mart.) against Vincristine in Vitro Exposure.
Veloso CF, Machado AK, Cadoná FC, Azzolin VF, Cruz IBM, Silveira AF. Veloso CF, et al. J Prev Alzheimers Dis. 2018;5(1):65-70. doi: 10.14283/jpad.2017.45. J Prev Alzheimers Dis. 2018. PMID: 29405235
After that, cells were exposed to VCR and guarana extract to evaluate the neuroprotective effect of guarana. ...CONCLUSIONS: In this sense, guarana is a remarkable antioxidant fruit that could be a target in new therapies development to reduce VCR neurotoxici …
After that, cells were exposed to VCR and guarana extract to evaluate the neuroprotective effect of guarana. ...CONCLUSIONS: I …
Effects of Carbohydrate, Caffeine, and Guarana on Cognitive Performance, Perceived Exertion, and Shooting Performance in High-Level Athletes.
Pomportes L, Brisswalter J, Hays A, Davranche K. Pomportes L, et al. Int J Sports Physiol Perform. 2019 May 1;14(5):576-582. doi: 10.1123/ijspp.2017-0865. Epub 2019 Apr 11. Int J Sports Physiol Perform. 2019. PMID: 30300016
Purpose: To investigate the effect of ingesting carbohydrate (CHO), caffeine (CAF), and a guarana complex (GUAc) during a running exercise on cognitive performance, rating of perceived exertion (RPE), and shooting performance in high-level modern pentathlon athletes. ...
Purpose: To investigate the effect of ingesting carbohydrate (CHO), caffeine (CAF), and a guarana complex (GUAc) during a running exe …
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