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Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice.
Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM. Gregorius J, et al. Among authors: gunzer m. Basic Res Cardiol. 2021 Jun 8;116(1):40. doi: 10.1007/s00395-021-00881-9. Basic Res Cardiol. 2021. PMID: 34105014 Free PMC article.
Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model.
Metzger P, Kirchleitner SV, Boehmer DFR, Hörth C, Eisele A, Ormanns S, Gunzer M, Lech M, Lauber K, Endres S, Duewell P, Schnurr M, König LM. Metzger P, et al. Among authors: gunzer m. Cancer Immunol Immunother. 2020 Oct;69(10):2101-2112. doi: 10.1007/s00262-020-02605-9. Epub 2020 May 24. Cancer Immunol Immunother. 2020. PMID: 32448983 Free PMC article.
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin.
Männ L, Kochupurakkal N, Martin C, Verjans E, Klingberg A, Sody S, Kraus A, Dalimot J, Bergmüller E, Jung S, Voortman S, Winterhager E, Brandau S, Garbi N, Kurrer M, Eriksson U, Gunzer M, Hasenberg M. Männ L, et al. Among authors: gunzer m. Eur J Immunol. 2016 Aug;46(8):2028-42. doi: 10.1002/eji.201546245. Epub 2016 Jun 8. Eur J Immunol. 2016. PMID: 27184067 Free article.
ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo.
Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S. Rolle AM, et al. Among authors: gunzer m. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1026-33. doi: 10.1073/pnas.1518836113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787852 Free PMC article.