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Is there a 'gut-brain-skin axis'?
Arck P, Handjiski B, Hagen E, Pincus M, Bruenahl C, Bienenstock J, Paus R. Arck P, et al. Exp Dermatol. 2010 May;19(5):401-5. doi: 10.1111/j.1600-0625.2009.01060.x. Epub 2010 Jan 25. Exp Dermatol. 2010. PMID: 20113345
Emerging evidence arising from interdisciplinary research supports the occurrence of communication axes between organs, such as the brain-gut or brain-skin axis. The latter is employed in response to stress challenge, along which neurogen …
Emerging evidence arising from interdisciplinary research supports the occurrence of communication axes between organs, such as the brain …
Revisiting Rosacea Through the Skin-Gut-Brain Axis: A Neuroimmune Perspective.
Lazić Mosler E, Vekić Mužević M, Karlović D, Tarle M, Raguž M. Lazić Mosler E, et al. Life (Basel). 2026 Feb 18;16(2):347. doi: 10.3390/life16020347. Life (Basel). 2026. PMID: 41752982 Free PMC article. Review.
Rosacea is increasingly recognized as a complex inflammatory disorder extending beyond isolated cutaneous pathology, involving dysregulated interactions between the skin, gastrointestinal system, and central nervous system. The skin-gut-brain axis …
Rosacea is increasingly recognized as a complex inflammatory disorder extending beyond isolated cutaneous pathology, involving dysregulated …
Daily skin-to-skin contact alters microbiota development in healthy full-term infants.
Eckermann HA, Meijer J, Cooijmans K, Lahti L, de Weerth C. Eckermann HA, et al. Gut Microbes. 2024 Jan-Dec;16(1):2295403. doi: 10.1080/19490976.2023.2295403. Epub 2024 Jan 10. Gut Microbes. 2024. PMID: 38197254 Free PMC article. Clinical Trial.
In this randomized controlled trial, the gut microbiota was obtained as a secondary outcome measure in a study on the effects of one hour of daily skin-to-skin contact (SSC) for five weeks in healthy full-term infants. Specifically, we studied the effects on …
In this randomized controlled trial, the gut microbiota was obtained as a secondary outcome measure in a study on the effects of one …
The brain-gut-skin axis in inflammatory and disfiguring skin diseases: mechanistic insights, clinical correlations, and therapeutic strategies.
Guo Z, Yang J, Zang R, Yang Y, Wang Q, Xu C. Guo Z, et al. Front Immunol. 2026 Feb 27;17:1737303. doi: 10.3389/fimmu.2026.1737303. eCollection 2026. Front Immunol. 2026. PMID: 41836406 Free PMC article. Review.
Emerging evidence suggests that the brain-gut-skin axis (BGSA) plays a critical role in the pathogenesis of inflammatory and disfiguring skin diseases. Conditions such as acne, atopic dermatitis, psoriasis, rosacea, vitiligo, and alopecia areata …
Emerging evidence suggests that the brain-gut-skin axis (BGSA) plays a critical role in the pathogenesis of infl …
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, … See abstract for full author list ➔ Klionsky DJ, et al. Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Autophagy. 2016. PMID: 26799652 Free PMC article. No abstract available.
Acne vulgaris, probiotics and the gut-brain-skin axis: from anecdote to translational medicine.
Bowe W, Patel NB, Logan AC. Bowe W, et al. Benef Microbes. 2014 Jun 1;5(2):185-99. doi: 10.3920/BM2012.0060. Benef Microbes. 2014. PMID: 23886975 Review.
They were also among the first to propose the use of probiotic Lactobacillus acidophilus cultures. In recent years, aspects of this gut-brain-skin theory have been further validated via modern scientific investigations. ...Here we provide a historical backgro …
They were also among the first to propose the use of probiotic Lactobacillus acidophilus cultures. In recent years, aspects of this gut …
The Effect of a Probiotic Complex on the Gut-Brain Axis: A Translational Study.
Nobile V, Giardina S, Puoci F. Nobile V, et al. Neuropsychobiology. 2022;81(2):116-126. doi: 10.1159/000518385. Epub 2021 Aug 30. Neuropsychobiology. 2022. PMID: 34515196
BACKGROUND: The gut-brain axis refers to the network of connections that involve multiple biologic systems, allowing bidirectional communication between the gut and the brain. ...As such, keeping a balanced gut microbiota through probioti …
BACKGROUND: The gut-brain axis refers to the network of connections that involve multiple biologic systems, allowing bi …
Brain-organ axis: How does stress regulate peripheral immunity through neural signaling?
Yu X, Zhu H, Su Y, Zhou L, Chen Z, Li P, Wang Y. Yu X, et al. Phys Life Rev. 2026 Jul;57:164-179. doi: 10.1016/j.plrev.2026.04.001. Epub 2026 Apr 7. Phys Life Rev. 2026. PMID: 41967255 Free article. Review.
To better elucidate how the brain responds to external stressors, we propose the concept of the "brain-organ axis." ...This review integrates the recent findings on the brain-organ axis in the context of stress and psychological disorders …
To better elucidate how the brain responds to external stressors, we propose the concept of the "brain-organ axis." ... …
Nanoplastics and Neurodegeneration in ALS.
Eisen A, Pioro EP, Goutman SA, Kiernan MC. Eisen A, et al. Brain Sci. 2024 May 7;14(5):471. doi: 10.3390/brainsci14050471. Brain Sci. 2024. PMID: 38790450 Free PMC article. Review.
Within the brain, MNPLs initiate an inflammatory response with pro-inflammatory cytokine production, oxidative stress with generation of reactive oxygen species, and mitochondrial dysfunction. ...Water and many foods contain MNPLs and in humans, ingestion is the mai …
Within the brain, MNPLs initiate an inflammatory response with pro-inflammatory cytokine production, oxidative stress with gen …
Stress gets into the belly: Early life stress and the gut microbiome.
Hantsoo L, Zemel BS. Hantsoo L, et al. Behav Brain Res. 2021 Sep 24;414:113474. doi: 10.1016/j.bbr.2021.113474. Epub 2021 Jul 16. Behav Brain Res. 2021. PMID: 34280457 Free PMC article. Review.
We review animal and human research utilizing a variety of stress paradigms (acute laboratory stressors, chronic stress, stressful life events, perceived stress, ELS, in utero stress) and their impacts on the gut microbiota, with a partic …
We review animal and human research utilizing a variety of stress paradigms (acute laboratory stressors, chronic stress, st …
38 results