Gut-microbiota-derived indole sulfate promotes heart failure in chronic kidney disease.
Zhang Y, Han X, Feng T, Li Z, Yu H, Chen Y, Gao Y, Gao Q, Zhang L, Li S, Shi L, Zhang X, Li Z, Li Y, Zhou H.
Zhang Y, et al.
Cell Host Microbe. 2025 Oct 8;33(10):1715-1730.e5. doi: 10.1016/j.chom.2025.08.014. Epub 2025 Sep 16.
Cell Host Microbe. 2025.
PMID: 40961933
Free article.
Heart failure (HF) is highly prevalent in chronic kidney disease (CKD) and associates with alterations in gut microbiota, although the underlying mechanisms remain unclear, complicating diagnosis and treatment. ...Mechanistically, IS disrupts cardiac m …
Heart failure (HF) is highly prevalent in chronic kidney disease (CKD) and associates with alterations in gut mi …