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In vitro antimicrobial potential of extracts and phytoconstituents from Gymnema sylvestre R.Br. leaves and their biosafety evaluation.
Arora DS, Sood H. Arora DS, et al. AMB Express. 2017 Dec;7(1):115. doi: 10.1186/s13568-017-0416-z. Epub 2017 Jun 5. AMB Express. 2017. PMID: 28587443 Free PMC article.
The in vitro antimicrobial screening of Gymnema sylvestre leaves against 13 test pathogens established its broad spectrum activity with average inhibition zone ranging from 14 to 23 mm. ...The MIC and time kill study was also compared to that of standard antibiotics …
The in vitro antimicrobial screening of Gymnema sylvestre leaves against 13 test pathogens established its broad spectrum acti …
Separation of Bioactive Small Molecules, Peptides from Natural Sources and Proteins from Microbes by Preparative Isoelectric Focusing (IEF) Method.
Veerapandian R, Paudyal A, Chang A, Vediyappan G. Veerapandian R, et al. J Vis Exp. 2020 Jun 14;(160). doi: 10.3791/61101. J Vis Exp. 2020. PMID: 32597857
We have used the method for complex biological sample fractionation and characterization. As a proof of concept, we fractionated a Gymnema sylvestre plant extract, isolating a family of terpenoid saponin small molecules and a peptide. We also demonstrated effective …
We have used the method for complex biological sample fractionation and characterization. As a proof of concept, we fractionated a Gymnem
Gymnemic acids inhibit hyphal growth and virulence in Candida albicans.
Vediyappan G, Dumontet V, Pelissier F, d'Enfert C. Vediyappan G, et al. PLoS One. 2013 Sep 11;8(9):e74189. doi: 10.1371/journal.pone.0074189. eCollection 2013. PLoS One. 2013. PMID: 24040201 Free PMC article.
Candida albicans is an opportunistic and polymorphic fungal pathogen that causes mucosal, disseminated and invasive infections in humans. ...Here, we have identified the triterpenoid saponin family of gymnemic acids (GAs) as inhibitor of C. albicans morphogenesis. GAs were
Candida albicans is an opportunistic and polymorphic fungal pathogen that causes mucosal, disseminated and invasive infections in hum