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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1971 1
1972 1
1973 1
1974 4
1975 4
1976 2
1977 2
1978 6
1979 7
1980 5
1981 9
1982 10
1983 12
1984 17
1985 10
1986 15
1987 11
1988 9
1989 20
1990 31
1991 20
1992 36
1993 27
1994 41
1995 28
1996 29
1997 46
1998 32
1999 39
2000 38
2001 49
2002 36
2003 45
2004 53
2005 50
2006 57
2007 52
2008 56
2009 52
2010 42
2011 44
2012 56
2013 52
2014 32
2015 46
2016 42
2017 27
2018 35
2019 33
2020 37
2021 27
2022 19
2023 11
2024 24
2025 25
2026 7

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1,381 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Haloperidol in treating delirium, reducing mortality, and preventing delirium occurrence: Bayesian and frequentist meta-analyses.
Cheng SL, Hsu TW, Kao YC, Yu CL, Thompson T, Carvalho AF, Stubbs B, Tseng PT, Hsu CW, Yang FC, Tu YK, Liang CS. Cheng SL, et al. Crit Care. 2025 Mar 20;29(1):126. doi: 10.1186/s13054-025-05342-6. Crit Care. 2025. PMID: 40114217 Free PMC article. Review.
BACKGROUND: Although haloperidol is commonly used to treat or prevent delirium in intensive care unit (ICU) patients, the evidence remains inconclusive. ...The probabilities of haloperidol causing CIH (RD > 0.02) across all other safety outcomes were low (all &lt …
BACKGROUND: Although haloperidol is commonly used to treat or prevent delirium in intensive care unit (ICU) patients, the evidence re …
Intravenous Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC): A Randomized, Controlled Trial.
Ruberto AJ, Sivilotti MLA, Forrester S, Hall AK, Crawford FM, Day AG. Ruberto AJ, et al. Ann Emerg Med. 2021 Jun;77(6):613-619. doi: 10.1016/j.annemergmed.2020.08.021. Epub 2020 Nov 5. Ann Emerg Med. 2021. PMID: 33160719 Clinical Trial.
Anecdotal evidence supports the use of haloperidol over traditional antiemetics for this newly recognized disorder. We compare haloperidol with ondansetron for cannabis hyperemesis syndrome. ...There were 2 return visits for acute dystonia, both in the higher-dose …
Anecdotal evidence supports the use of haloperidol over traditional antiemetics for this newly recognized disorder. We compare hal …
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial.
Hui D, Frisbee-Hume S, Wilson A, Dibaj SS, Nguyen T, De La Cruz M, Walker P, Zhukovsky DS, Delgado-Guay M, Vidal M, Epner D, Reddy A, Tanco K, Williams J, Hall S, Liu D, Hess K, Amin S, Breitbart W, Bruera E. Hui D, et al. JAMA. 2017 Sep 19;318(11):1047-1056. doi: 10.1001/jama.2017.11468. JAMA. 2017. PMID: 28975307 Free PMC article. Clinical Trial.
The lorazepam + haloperidol group required less median rescue neuroleptics (2.0 mg) than the placebo + haloperidol group (4.0 mg) (median difference, -1.0 mg [95% CI, -2.0 to 0]; P = .009) and was perceived to be more comfortable by both blinded caregivers and nurse …
The lorazepam + haloperidol group required less median rescue neuroleptics (2.0 mg) than the placebo + haloperidol group (4.0 …
Haloperidol Versus Atypical Antipsychotics for Delirium in Hospitalized and ICU Patients: A Systematic Review and Meta-analysis.
Cruccioli MM, Carneiro PHT, Pitanga JFJ, Ferreira CC, Leão RC, Loures ML, Lima CR, Fraiman P, Sarmento FP. Cruccioli MM, et al. Clin Neuropharmacol. 2025 Sep-Oct 01;48(5):145-150. doi: 10.1097/WNF.0000000000000650. Epub 2025 Aug 27. Clin Neuropharmacol. 2025. PMID: 40939180
However, despite increasing access to atypical antipsychotics in hospital settings, robust analyses of studies comparing the effectiveness of haloperidol and atypical antipsychotics are lacking. OBJECTIVES: To conduct a systematic review and meta-analysis of randomized con …
However, despite increasing access to atypical antipsychotics in hospital settings, robust analyses of studies comparing the effectiveness o …
Haloperidol (oral) versus olanzapine (oral) for people with schizophrenia and schizophrenia-spectrum disorders.
Ibragimov K, Keane GP, Carreño Glaría C, Cheng J, Llosa AE. Ibragimov K, et al. Cochrane Database Syst Rev. 2024 Jul 3;7(7):CD013425. doi: 10.1002/14651858.CD013425.pub2. Cochrane Database Syst Rev. 2024. PMID: 38958149 Free PMC article.
SELECTION CRITERIA: Randomised clinical trials comparing haloperidol with olanzapine for people with schizophrenia and schizophrenia-spectrum disorders. ...For every three people treated with haloperidol instead of olanzapine, one additional person would experience …
SELECTION CRITERIA: Randomised clinical trials comparing haloperidol with olanzapine for people with schizophrenia and schizophrenia- …
Haloperidol for preventing delirium in ICU patients: a systematic review and meta-analysis.
Marra A, Vargas M, Buonanno P, Iacovazzo C, Kotfis K, Servillo G. Marra A, et al. Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1582-1591. doi: 10.26355/eurrev_202102_24868. Eur Rev Med Pharmacol Sci. 2021. PMID: 33629327 Free article.
Therefore, we conducted a systematic review of the benefits of haloperidol for the prevention of delirium in ICU patients. MATERIALS AND METHODS: We made a systematic review and meta-analysis. ...Haloperidol did not increase the sedation level (RR: 1.88, 95% CI: 0.7 …
Therefore, we conducted a systematic review of the benefits of haloperidol for the prevention of delirium in ICU patients. MATERIALS …
Haloperidol alone or in combination for acute mania.
Cipriani A, Rendell JM, Geddes JR. Cipriani A, et al. Cochrane Database Syst Rev. 2006 Jul 19;2006(3):CD004362. doi: 10.1002/14651858.CD004362.pub2. Cochrane Database Syst Rev. 2006. PMID: 16856043 Free PMC article.
No significant differences between haloperidol and risperidone, olanzapine, carbamazepine or valproate were found. Compared with placebo, a statistically significant difference in favour of haloperidol in failure to complete treatment (RR 0.74, 95% Cl 0.57 to 0.96) …
No significant differences between haloperidol and risperidone, olanzapine, carbamazepine or valproate were found. Compared with plac …
Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation).
Ostinelli EG, Brooke-Powney MJ, Li X, Adams CE. Ostinelli EG, et al. Cochrane Database Syst Rev. 2017 Jul 31;7(7):CD009377. doi: 10.1002/14651858.CD009377.pub3. Cochrane Database Syst Rev. 2017. PMID: 28758203 Free PMC article.
More people in the haloperidol group experienced dystonia (2 RCTs, n=477, RR 6.63, 95%CI 1.52 to 28.86, very low-quality evidence).Four trials (n=207) compared haloperidol with lorazepam with no significant differences with regard to number of participants asleep at …
More people in the haloperidol group experienced dystonia (2 RCTs, n=477, RR 6.63, 95%CI 1.52 to 28.86, very low-quality evidence).Fo …
Haloperidol for the treatment of delirium in critically ill patients: A systematic review with meta-analysis and Trial Sequential Analysis.
Barbateskovic M, Krauss SR, Collet MO, Andersen-Ranberg NC, Mathiesen O, Jakobsen JC, Perner A, Wetterslev J. Barbateskovic M, et al. Acta Anaesthesiol Scand. 2020 Feb;64(2):254-266. doi: 10.1111/aas.13501. Epub 2019 Nov 23. Acta Anaesthesiol Scand. 2020. PMID: 31663112
BACKGROUND: Haloperidol is the most frequently used drug to treat delirium in the critically ill patients. ...Sensitivity analyses, including trials using rescue haloperidol, did not change the results. CONCLUSIONS: The evidence for the use of haloperidol to …
BACKGROUND: Haloperidol is the most frequently used drug to treat delirium in the critically ill patients. ...Sensitivity analyses, i …
Haloperidol versus chlorpromazine for schizophrenia.
Leucht C, Kitzmantel M, Chua L, Kane J, Leucht S. Leucht C, et al. Cochrane Database Syst Rev. 2008 Jan 23;2008(1):CD004278. doi: 10.1002/14651858.CD004278.pub2. Cochrane Database Syst Rev. 2008. PMID: 18254045 Free PMC article.
OBJECTIVES: To compare the effects of haloperidol and chlorpromazine for people with schizophrenia and schizophrenia-like psychoses. ...However, it seems that haloperidol causes more movement disorders than chlorpromazine, while chlorpromazine is significantly more …
OBJECTIVES: To compare the effects of haloperidol and chlorpromazine for people with schizophrenia and schizophrenia-like psychoses. …
1,381 results