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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1986 1
1989 1
1990 1
1991 2
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1995 5
1996 2
1997 5
1998 5
1999 6
2000 11
2001 12
2002 8
2003 17
2004 10
2005 18
2006 8
2007 14
2008 9
2009 9
2010 17
2011 9
2012 9
2013 12
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317 results

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Page 1
QT Prolongation, Torsades de Pointes, and Psychotropic Medications: A 5-Year Update.
Beach SR, Celano CM, Sugrue AM, Adams C, Ackerman MJ, Noseworthy PA, Huffman JC. Beach SR, et al. Psychosomatics. 2018 Mar-Apr;59(2):105-122. doi: 10.1016/j.psym.2017.10.009. Epub 2017 Nov 3. Psychosomatics. 2018. PMID: 29275963 Review.
BACKGROUND: Some psychotropic medications have been associated with prolongation of the QT interval and QT prolongation, especially in those with medical illness, and are linked to lethal ventricular arrhythmias, such as Torsades de Pointes (TdP). ...Escitalo …
BACKGROUND: Some psychotropic medications have been associated with prolongation of the QT interval and QT prolongation, espec …
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.
Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P. Weibel S, et al. Cochrane Database Syst Rev. 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. Cochrane Database Syst Rev. 2020. PMID: 33075160 Free PMC article.
We performed pair-wise meta-analyses for drugs of direct interest (amisulpride, aprepitant, casopitant, dexamethasone, dimenhydrinate, dolasetron, droperidol, fosaprepitant, granisetron, haloperidol, meclizine, methylprednisolone, metoclopramide, ondansetron, palonosetron, …
We performed pair-wise meta-analyses for drugs of direct interest (amisulpride, aprepitant, casopitant, dexamethasone, dimenhydrinate, dolas …
Major adverse cardiac events with haloperidol: A meta-analysis.
Garcia MC, Anderson M, Li M, Zewdu M, Schneider T, Matos-Silva J, Ramnarine G, Rong K, Mbuagbaw L, Holbrook A. Garcia MC, et al. PLoS One. 2025 Jun 25;20(6):e0326804. doi: 10.1371/journal.pone.0326804. eCollection 2025. PLoS One. 2025. PMID: 40561150 Free PMC article.
BACKGROUND: Haloperidol is a commonly used antipsychotic drug and a frequent source of medication safety alerts because of its listing as a "known risk" QT interval-prolonging medication (QTPmed). ...There was no difference in MACE with exposure to haloperidol …
BACKGROUND: Haloperidol is a commonly used antipsychotic drug and a frequent source of medication safety alerts because of its listin …
Intravenous haloperidol: A systematic review of side effects and recommendations for clinical use.
Beach SR, Gross AF, Hartney KE, Taylor JB, Rundell JR. Beach SR, et al. Gen Hosp Psychiatry. 2020 Nov-Dec;67:42-50. doi: 10.1016/j.genhosppsych.2020.08.008. Epub 2020 Aug 22. Gen Hosp Psychiatry. 2020. PMID: 32979582
Over the years, concerns have emerged regarding side effects of IVH, particularly its potential to cause QT prolongation, torsades de pointes (TdP), extrapyramidal symptoms and catatonia. METHODS: We conducted a systematic review of literature of published literatur …
Over the years, concerns have emerged regarding side effects of IVH, particularly its potential to cause QT prolongation, torsades …
QT interval prolongation in acute antipsychotic poisoning: systematic review and recommendations.
Berling I, Yates C, Hoffman RS, Hatten BW, Roberts DM, Wong A, Hoegberg LCG, Lonati D, Ferrer Dufol AMA, Hayes BD, Isbister GK, Paasma R, Heyerdahl F, Mackenzie CA, Othong R, Stanton M, Smith A, Gosselin S. Berling I, et al. Clin Toxicol (Phila). 2025 Nov;63(11):810-837. doi: 10.1080/15563650.2025.2554950. Epub 2025 Nov 19. Clin Toxicol (Phila). 2025. PMID: 41255343 Free article.
INTRODUCTION: Antipsychotic medications are often associated with QT interval prolongation, which can lead to ventricular dysrhythmias, including torsade de pointes. ...The QT Interval Prolongation in Clinical Toxicology Workgroup suggests the same approach f …
INTRODUCTION: Antipsychotic medications are often associated with QT interval prolongation, which can lead to ventricular dysrhythmia …
Comparative physiological effects of antipsychotic drugs in children and young people: a network meta-analysis.
Rogdaki M, McCutcheon RA, D'Ambrosio E, Mancini V, Watson CJ, Fanshawe JB, Carr R, Telesia L, Martini MG, Philip A, Gilbert BJ, Salazar-de-Pablo G, Kyriakopoulos M, Siskind D, Correll CU, Cipriani A, Efthimiou O, Howes OD, Pillinger T. Rogdaki M, et al. Lancet Child Adolesc Health. 2024 Jul;8(7):510-521. doi: 10.1016/S2352-4642(24)00098-1. Lancet Child Adolesc Health. 2024. PMID: 38897716 Free PMC article.
Primary outcomes were mean change from baseline to end of acute treatment in bodyweight, BMI, fasting glucose, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, prolactin, heart rate, systolic blood pressure (SBP), and QT interval corrected for heart rate …
Primary outcomes were mean change from baseline to end of acute treatment in bodyweight, BMI, fasting glucose, total cholesterol, LDL choles …
Risk Stratification of QTc Prolongation in Critically Ill Patients Receiving Antipsychotics for the Management of Delirium Symptoms.
Sadlonova M, Beach SR, Funk MC, Rosen JH, Ramirez Gamero AF, Karlson RA, Huffman JC, Celano CM. Sadlonova M, et al. J Intensive Care Med. 2025 Apr;40(4):355-371. doi: 10.1177/08850666231222470. Epub 2023 Dec 21. J Intensive Care Med. 2025. PMID: 38130132 Review.
In this targeted review, we describe the evidence regarding the relationships between antipsychotic medications and QTc prolongation and practical methods for monitoring the QTc interval and mitigating arrhythmia risk.MethodsSearches of PubMed and Cochrane Library were performed …
In this targeted review, we describe the evidence regarding the relationships between antipsychotic medications and QTc prolongation and pra …
Intramuscular haloperidol or lorazepam and QT intervals in schizophrenia.
Harvey AT, Flockhart D, Gorski JC, Greenblatt DJ, Burke M, Werder S, Preskorn SH. Harvey AT, et al. J Clin Pharmacol. 2004 Oct;44(10):1173-84. doi: 10.1177/0091270004267807. J Clin Pharmacol. 2004. PMID: 15342619 Clinical Trial.
Although prolongation of the QT interval and sequelae, including torsade de pointes and death, have been reported for haloperidol (but not lorazepam), formal studies have been lacking. ...An association between QT prolongation and occurrence of extrapy …
Although prolongation of the QT interval and sequelae, including torsade de pointes and death, have been reported for halop …
Incidences, risk factors, and clinical correlates of severe QT prolongation after the use of quetiapine or haloperidol.
Wang CL, Wu VC, Lee CH, Wu CL, Chen HM, Huang YT, Chang SH. Wang CL, et al. Heart Rhythm. 2024 Mar;21(3):321-328. doi: 10.1016/j.hrthm.2023.10.027. Epub 2024 Jan 15. Heart Rhythm. 2024. PMID: 38231170
BACKGROUND: Case reports suggest that quetiapine or haloperidol use is associated with severe QT prolongation (SQTP) and torsades de pointes. ...SQTP was defined as a posttreatment corrected QT (QTc) interval exceeding 500 ms or an increase in QTc inte …
BACKGROUND: Case reports suggest that quetiapine or haloperidol use is associated with severe QT prolongation (SQTP) and to …
Agitated Psychiatric Patient.
Pabst BM, Leung C, Frey JA, Yee J. Pabst BM, et al. J Educ Teach Emerg Med. 2020 Oct 15;5(4):S59-S83. doi: 10.21980/J85352. eCollection 2020 Oct. J Educ Teach Emerg Med. 2020. PMID: 37465334 Free PMC article.
Chemical and/or physical restraints are sometimes necessary to ensure patient and staff safety when verbal de-escalation is ineffective, particularly since agitation is the leading cause of hospital staff injuries.2 Chemical restraints have been shown to be less physically trauma …
Chemical and/or physical restraints are sometimes necessary to ensure patient and staff safety when verbal de-escalation is ineffective, par …
317 results