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Anti-Atherogenic Protection by Oligomeric Proanthocyanidins via Regulating Collagen Crosslinking Against CC Diet-Induced Atherosclerosis in Rats.
Jamuna S, Ashokkumar R, Raja IS, Devaraj SN. Jamuna S, et al. Appl Biochem Biotechnol. 2023 Aug;195(8):4881-4892. doi: 10.1007/s12010-023-04487-w. Epub 2023 Apr 25. Appl Biochem Biotechnol. 2023. PMID: 37097399
Growing evidences demonstrated that consumption of antioxidant rich diet is highly associated with a reduced risk of atherosclerosis. Oligomeric proanthocyanidins (OPC) have been proved to possess promising antioxidant, anti-inflammatory and cardioprotective activit …
Growing evidences demonstrated that consumption of antioxidant rich diet is highly associated with a reduced risk of atherosclerosis. Oligom …
Inhibition of differentiation of monocyte to macrophages in atherosclerosis by oligomeric proanthocyanidins -In-vivo and in-vitro study.
Mohana T, Navin AV, Jamuna S, Sakeena Sadullah MS, Niranjali Devaraj S. Mohana T, et al. Food Chem Toxicol. 2015 Aug;82:96-105. doi: 10.1016/j.fct.2015.04.028. Epub 2015 May 14. Food Chem Toxicol. 2015. PMID: 25981678
In the current study we explored hypercholesterolemia induced monocyte to macrophage differentiation in-vivo (Wistar rats) leading to atherosclerosis and OxyLDL, M-CSF induced monocyte differentiation in-vitro (U937 cells). Oligomeric proanthocyanidin (OPC) isolated …
In the current study we explored hypercholesterolemia induced monocyte to macrophage differentiation in-vivo (Wistar rats) leading to athero …
Phenylpropanoid-substituted procyanidins and tentatively identified procyanidin glycosides from hawthorn (Crataegus spp.).
Sendker J, Petereit F, Lautenschläger M, Hellenbrand N, Hensel A. Sendker J, et al. Planta Med. 2013 Jan;79(1):45-51. doi: 10.1055/s-0032-1327926. Epub 2012 Nov 15. Planta Med. 2013. PMID: 23154843
The rational use of hawthorn leafs and flowers from Crataegus spp. for declining cardiac performance is mainly due to flavon-C-glycosides and oligomeric procyanidins (OPC). From OPC-enriched extracts from different batches, a dimeric phenylpropanoid-su …
The rational use of hawthorn leafs and flowers from Crataegus spp. for declining cardiac performance is mainly due to flavon-C …
In vitro intestinal transport of oligomeric procyanidins (DP 2 to 4) across monolayers of Caco-2 cells.
Zumdick S, Deters A, Hensel A. Zumdick S, et al. Fitoterapia. 2012 Oct;83(7):1210-7. doi: 10.1016/j.fitote.2012.06.013. Epub 2012 Jul 6. Fitoterapia. 2012. PMID: 22776719
Extracts from hawthorn leafs and flowers (Crataegus sp., Rosaceae) are widely used as a rational based phytomedicine for declining cardiac performance. ...Mixtures of the different OPCs did not have an increased permeation. Transport experiments of complex OPC …
Extracts from hawthorn leafs and flowers (Crataegus sp., Rosaceae) are widely used as a rational based phytomedicine for decli …
[In vitro and in vivo studies on the cardioprotective action of oligomeric procyanidins in a Crataegus extract of leaves and blooms].
Chatterjee SS, Koch E, Jaggy H, Krzeminski T. Chatterjee SS, et al. Arzneimittelforschung. 1997 Jul;47(7):821-5. Arzneimittelforschung. 1997. PMID: 9324931 German.
Cardioprotective effects of a standardized extract from leaves with flowers of Crataegus (WS-1442; content of oligomeric procyandins [OPC]: 18.75%) have recently been demonstrated in an ischemia-reperfusion model in rats. ...The RS and HNE inhibitory activities of t …
Cardioprotective effects of a standardized extract from leaves with flowers of Crataegus (WS-1442; content of oligomeric procyandins …
Preparative isolation of oligomeric procyanidins from Hawthorn (Crataegus spp.).
Zumdick S, Petereit F, Luftmann H, Hensel A. Zumdick S, et al. Pharmazie. 2009 Apr;64(4):286-8. Pharmazie. 2009. PMID: 19435150
The oligomeric procyanidins (OPC) from Hawthorn leaves and flowers (Crataegi folium cum flore) are considered to be in part responsible for the cardiotonic clinical activity of the herbal material. ...Therefore the water soluble fraction of an acetone/water (7 + 3) …
The oligomeric procyanidins (OPC) from Hawthorn leaves and flowers (Crataegi folium cum flore) are considered to be in part re …