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Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany.
Wyss C, Gündling PW, Kostev K. Wyss C, et al. Sci Rep. 2024 Oct 3;14(1):22986. doi: 10.1038/s41598-024-74325-4. Sci Rep. 2024. PMID: 39362947 Free PMC article.
Hawthorn special extract WS 1442 has beneficial effects on the cardiovascular system. Experimental studies have shown an antiarrhythmic effect of the substance. ...The cumulative incidence of tachycardia was significantly lower in the WS 1442 gr …
Hawthorn special extract WS 1442 has beneficial effects on the cardiovascular system. Experimental studies have shown a …
Benefit-Risk Assessment of Crataegus Extract WS 1442: An Evidence-Based Review.
Holubarsch CJF, Colucci WS, Eha J. Holubarsch CJF, et al. Am J Cardiovasc Drugs. 2018 Feb;18(1):25-36. doi: 10.1007/s40256-017-0249-9. Am J Cardiovasc Drugs. 2018. PMID: 29080984 Free PMC article. Review.
Preparations from Crataegus (hawthorn) have a long history in the treatment of heart failure. WS 1442 is a dry extract from hawthorn leaves with flowers (4-6.6:1), extraction solvent of ethanol 45% (w/w), adjusted to 17.3-20.1% of oligomeric pro …
Preparations from Crataegus (hawthorn) have a long history in the treatment of heart failure. WS 1442 is a dry e …
Hawthorn special extract WS 1442 increases red blood cell NO-formation without altering red blood cell deformability.
Rieckeheer E, Schwinger RH, Bloch W, Brixius K. Rieckeheer E, et al. Phytomedicine. 2011 Dec 15;19(1):20-4. doi: 10.1016/j.phymed.2011.08.059. Epub 2011 Sep 6. Phytomedicine. 2011. PMID: 21899992
WS( ) 1442 is a special extract of hawthorn leaves with flowers used for the treatment of mild cardiac failure. ...CONCLUSION: WS( ) 1442 activates rbcNOS and causes NO-formation in RBCs. WS( ) 1442-dependent NO-formation however d …
WS( ) 1442 is a special extract of hawthorn leaves with flowers used for the treatment of mild cardiac failure. ...CONC …
Hawthorn revisited: time- and dose-dependent cardioprotective action of WS-1442 special extract in the reperfusion-induced arrhythmia model in rats in vivo.
Zorniak M, Porc MP, Krzeminski TF. Zorniak M, et al. J Physiol Pharmacol. 2019 Apr;70(2). doi: 10.26402/jpp.2019.2.14. Epub 2019 Aug 20. J Physiol Pharmacol. 2019. PMID: 31443093 Free article.
Standardized WS-1442 extract from Crataegus oxycantha (hawthorn) leaves and berries is one of the most widely studied preparations received from hawthorn. ...Analyzed data coming from a model of reperfusion-induced arrhythmias in rats suggests t …
Standardized WS-1442 extract from Crataegus oxycantha (hawthorn) leaves and berries is one of the most widely st …
Crataegus special extract WS 1442: up-to-date review of experimental and clinical experiences.
Zorniak M, Szydlo B, Krzeminski TF. Zorniak M, et al. J Physiol Pharmacol. 2017 Aug;68(4):521-526. J Physiol Pharmacol. 2017. PMID: 29151068 Free article. Review.
Extracts and tinctures made from Crataegus spp. (Hawthorn) have been used as cardioprotective remedies since ancient times. WS 1442 special extract, manufactured by Dr. W. Schwabe Pharmaceuticals , made from Crataegus spp. ...
Extracts and tinctures made from Crataegus spp. (Hawthorn) have been used as cardioprotective remedies since ancient times. …
Crataegus Extract WS 1442 Stimulates Cardiomyogenesis and Angiogenesis From Stem Cells: A Possible New Pharmacology for Hawthorn?
Halver J, Wenzel K, Sendker J, Carrillo García C, Erdelmeier CAJ, Willems E, Mercola M, Symma N, Könemann S, Koch E, Hensel A, Schade D. Halver J, et al. Front Pharmacol. 2019 Nov 27;10:1357. doi: 10.3389/fphar.2019.01357. eCollection 2019. Front Pharmacol. 2019. PMID: 31849643 Free PMC article.
Extracts from the leaves and flowers of Crataegus spp. (i.e., hawthorn species) have been traditionally used with documented preclinical and clinical activities in cardiovascular medicine. Based on reported positive effects on heart muscle after ischemic injury and …
Extracts from the leaves and flowers of Crataegus spp. (i.e., hawthorn species) have been traditionally used with documented p …
Crataegus Special Extract WS 1442 Effects on eNOS and microRNA 155.
Wang X, Liang Y, Shi J, Zhu HJ, Bleske BE. Wang X, et al. Planta Med. 2018 Oct;84(15):1094-1100. doi: 10.1055/a-0601-7083. Epub 2018 Apr 16. Planta Med. 2018. PMID: 29660753
Factors that have been shown to increase expression of miR-155 may be mitigated by WS 1442, an extract of hawthorn leaves and flowers (Crataegus special extract) that contains a range of pharmacologically active substances including oligomeric proantho …
Factors that have been shown to increase expression of miR-155 may be mitigated by WS 1442, an extract of hawthorn leav …
Prospective, comparative cohort studies and their contribution to the benefit assessments of therapeutic options: heart failure treatment with and without Hawthorn special extract WS 1442.
Habs M. Habs M. Forsch Komplementarmed Klass Naturheilkd. 2004 Aug;11 Suppl 1:36-9. doi: 10.1159/000080574. Forsch Komplementarmed Klass Naturheilkd. 2004. PMID: 15353901
OBJECTIVE: One of the trials which addresses this task is the WISO cohort study (Efficacy and socio-economic relevance of treatment of chronic heart failure stage NYHA II with Crataegus extract WS 1442). It compares two different therapeutic strategies …
OBJECTIVE: One of the trials which addresses this task is the WISO cohort study (Efficacy and socio-economic relevance of treatment of chron …
The vascular barrier-protecting hawthorn extract WS 1442 raises endothelial calcium levels by inhibition of SERCA and activation of the IP3 pathway.
Willer EA, Malli R, Bondarenko AI, Zahler S, Vollmar AM, Graier WF, Fürst R. Willer EA, et al. J Mol Cell Cardiol. 2012 Oct;53(4):567-77. doi: 10.1016/j.yjmcc.2012.07.002. Epub 2012 Jul 16. J Mol Cell Cardiol. 2012. PMID: 22814436
WS 1442 has been proven as an effective and safe therapeutical to treat mild forms of congestive heart failure. ...WS 1442 interfered with SERCA and the IP(3) pathway without inducing SOCE. The elucidation of this intriguing mechanism helps to unders …
WS 1442 has been proven as an effective and safe therapeutical to treat mild forms of congestive heart failure. ...WS …
Nanomechanics and sodium permeability of endothelial surface layer modulated by hawthorn extract WS 1442.
Peters W, Drüppel V, Kusche-Vihrog K, Schubert C, Oberleithner H. Peters W, et al. PLoS One. 2012;7(1):e29972. doi: 10.1371/journal.pone.0029972. Epub 2012 Jan 10. PLoS One. 2012. PMID: 22253842 Free PMC article.
By means of combined atomic force-epifluorescence microscopy we studied the impact of the hawthorn (Crataegus spp.) extract WS 1442, a herbal therapeutic with unknown mechanism of action, on the mechanics of the ESL of ex vivo murine aortae. Furthermor …
By means of combined atomic force-epifluorescence microscopy we studied the impact of the hawthorn (Crataegus spp.) extract …
39 results