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82 results

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Page 1
The history and promising future of phage therapy in the military service.
Gelman D, Eisenkraft A, Chanishvili N, Nachman D, Coppenhagem Glazer S, Hazan R. Gelman D, et al. Among authors: hazan r. J Trauma Acute Care Surg. 2018 Jul;85(1S Suppl 2):S18-S26. doi: 10.1097/TA.0000000000001809. J Trauma Acute Care Surg. 2018. PMID: 29370056 Review.
These strains, frequently isolated from military-associated environments, have created an urgent need to develop supplementary anti-infective modalities. One of the leading directions is phage therapy, which includes the administration of bacteriophages, viruses tha …
These strains, frequently isolated from military-associated environments, have created an urgent need to develop supplementary anti-infectiv …
Phage Therapy in Israel, Past, Present, and Future.
Rimon A, Gelman D, Yerushalmy O, Coppenhagen-Glazer S, Katvan E, Nir-Paz R, Hazan R. Rimon A, et al. Among authors: hazan r. Phage (New Rochelle). 2022 Jun 1;3(2):85-94. doi: 10.1089/phage.2022.0010. Epub 2022 Jun 16. Phage (New Rochelle). 2022. PMID: 36157284 Free PMC article. Review.
The fascinating scientific history of phage therapy has been documented in numerous publications. In this study, however, we focus on an angle of the story that hitherto has remained relatively neglected, namely, phage therapy treatments, and the protagonists that c …
The fascinating scientific history of phage therapy has been documented in numerous publications. In this study, however, we focus on …
Topical phage therapy in a mouse model of Cutibacterium acnes-induced acne-like lesions.
Rimon A, Rakov C, Lerer V, Sheffer-Levi S, Oren SA, Shlomov T, Shasha L, Lubin R, Zubeidat K, Jaber N, Mujahed M, Wilensky A, Coppenhagen-Glazer S, Molho-Pessach V, Hazan R. Rimon A, et al. Among authors: hazan r. Nat Commun. 2023 Feb 22;14(1):1005. doi: 10.1038/s41467-023-36694-8. Nat Commun. 2023. PMID: 36813793 Free PMC article.
For decades, antibiotics have been widely employed to treat acne vulgaris, inevitably resulting in increased bacterial antibiotic resistance. Phage therapy is a promising strategy to combat the growing challenge of antibiotic-resistant bacteria, utilizing viruses th …
For decades, antibiotics have been widely employed to treat acne vulgaris, inevitably resulting in increased bacterial antibiotic resistance …
Isolation and Characterization of Streptococcus mutans Phage as a Possible Treatment Agent for Caries.
Ben-Zaken H, Kraitman R, Coppenhagen-Glazer S, Khalifa L, Alkalay-Oren S, Gelman D, Ben-Gal G, Beyth N, Hazan R. Ben-Zaken H, et al. Among authors: hazan r. Viruses. 2021 May 2;13(5):825. doi: 10.3390/v13050825. Viruses. 2021. PMID: 34063251 Free PMC article.
Conventional treatment fails to specifically target the pathogenic bacteria, while tending to eradicate commensal bacteria. Thus, caries remains one of the most common and challenging diseases. ...Nevertheless, to date, only a few phages have been isolated ag …
Conventional treatment fails to specifically target the pathogenic bacteria, while tending to eradicate commensal bacteria. Th …
Phage therapy against Enterococcus faecalis in dental root canals.
Khalifa L, Shlezinger M, Beyth S, Houri-Haddad Y, Coppenhagen-Glazer S, Beyth N, Hazan R. Khalifa L, et al. Among authors: hazan r. J Oral Microbiol. 2016 Sep 16;8:32157. doi: 10.3402/jom.v8.32157. eCollection 2016. J Oral Microbiol. 2016. PMID: 27640530 Free PMC article. Review.
An effective response against such infections could be the use of bacteriophages (phages). Phage therapy was found to be highly effective against biofilm and multidrug-resistant bacteria and has other advantages like ease of isolation and possibilities …
An effective response against such infections could be the use of bacteriophages (phages). Phage therapy was found to b …
Evolthon: A community endeavor to evolve lab evolution.
Kaminski Strauss S, Schirman D, Jona G, Brooks AN, Kunjapur AM, Nguyen Ba AN, Flint A, Solt A, Mershin A, Dixit A, Yona AH, Csörgő B, Busby BP, Hennig BP, Pál C, Schraivogel D, Schultz D, Wernick DG, Agashe D, Levi D, Zabezhinsky D, Russ D, Sass E, Tamar E, Herz E, Levy ED, Church GM, Yelin I, Nachman I, Gerst JE, Georgeson JM, Adamala KP, Steinmetz LM, Rübsam M, Ralser M, Klutstein M, Desai MM, Walunjkar N, Yin N, Aharon Hefetz N, Jakimo N, Snitser O, Adini O, Kumar P, Soo Hoo Smith R, Zeidan R, Hazan R, Rak R, Kishony R, Johnson S, Nouriel S, Vonesch SC, Foster S, Dagan T, Wein T, Karydis T, Wannier TM, Stiles T, Olin-Sandoval V, Mueller WF, Bar-On YM, Dahan O, Pilpel Y. Kaminski Strauss S, et al. Among authors: hazan r. PLoS Biol. 2019 Mar 29;17(3):e3000182. doi: 10.1371/journal.pbio.3000182. eCollection 2019 Mar. PLoS Biol. 2019. PMID: 30925180 Free PMC article.
In yeast, the most successful strategies were those that used mating, underscoring the importance of sex in evolution. In bacteria, the fittest strain used a strategy based on exploration of different mutation rates. ...
In yeast, the most successful strategies were those that used mating, underscoring the importance of sex in evolution. In bacteria, t …
Alternative antimicrobial approach: nano-antimicrobial materials.
Beyth N, Houri-Haddad Y, Domb A, Khan W, Hazan R. Beyth N, et al. Among authors: hazan r. Evid Based Complement Alternat Med. 2015;2015:246012. doi: 10.1155/2015/246012. Epub 2015 Mar 16. Evid Based Complement Alternat Med. 2015. PMID: 25861355 Free PMC article. Review.
The present review discusses the activities of nanoparticles as an antimicrobial means, their mode of action, nanoparticle effect on drug-resistant bacteria, and the risks attendant on their use as antibacterial agents. Factors contributing to nanoparticle performance in t …
The present review discusses the activities of nanoparticles as an antimicrobial means, their mode of action, nanoparticle effect on drug-re …
Targeting Biofilm of MDR Providencia stuartii by Phages Using a Catheter Model.
Rakov C, Ben Porat S, Alkalay-Oren S, Yerushalmy O, Abdalrhman M, Gronovich N, Huang L, Pride D, Coppenhagen-Glazer S, Nir-Paz R, Hazan R. Rakov C, et al. Among authors: hazan r. Antibiotics (Basel). 2021 Apr 2;10(4):375. doi: 10.3390/antibiotics10040375. Antibiotics (Basel). 2021. PMID: 33918377 Free PMC article.
However, the number of available phages targeting Providencia spp. is extremely limited, restricting the use of phage therapy in such cases. In the present study, we describe the isolation and characterization of 17 lytic and temperate bacteriophages targetin …
However, the number of available phages targeting Providencia spp. is extremely limited, restricting the use of phage therapy …
Eukaryotic Adaptation to Years-Long Starvation Resembles that of Bacteria.
Aouizerat T, Gelman D, Szitenberg A, Gutman I, Glazer S, Reich E, Schoemann M, Kaplan R, Saragovi A, Hazan R, Klutstein M. Aouizerat T, et al. Among authors: hazan r. iScience. 2019 Sep 27;19:545-558. doi: 10.1016/j.isci.2019.08.002. Epub 2019 Aug 8. iScience. 2019. PMID: 31470363 Free PMC article.
The Growth Advantage in Stationary Phase (GASP) phenomenon, described in bacteria, reflects the genetic adaptation of bacteria to stress, including starvation, for a long time. ...
The Growth Advantage in Stationary Phase (GASP) phenomenon, described in bacteria, reflects the genetic adaptation of bacteria …
82 results