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Year Number of Results
1944 1
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1947 8
1948 8
1949 14
1950 7
1951 10
1952 9
1953 8
1954 14
1955 13
1956 10
1957 16
1958 15
1959 18
1960 21
1961 26
1962 18
1963 43
1964 49
1965 13
1966 10
1967 25
1968 50
1969 64
1970 93
1971 131
1972 152
1973 113
1974 133
1975 117
1976 63
1977 78
1978 79
1979 74
1980 71
1981 84
1982 83
1983 79
1984 122
1985 175
1986 166
1987 159
1988 184
1989 216
1990 221
1991 268
1992 260
1993 282
1994 322
1995 335
1996 329
1997 368
1998 361
1999 416
2000 470
2001 413
2002 455
2003 478
2004 492
2005 524
2006 615
2007 549
2008 624
2009 681
2010 692
2011 727
2012 762
2013 794
2014 831
2015 890
2016 1019
2017 905
2018 957
2019 969
2020 887
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2024 661
2025 790
2026 379

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22,276 results

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Page 1
Engineering Heart Morphogenesis.
Mandrycky CJ, Williams NP, Batalov I, El-Nachef D, de Bakker BS, Davis J, Kim DH, DeForest CA, Zheng Y, Stevens KR, Sniadecki NJ. Mandrycky CJ, et al. Trends Biotechnol. 2020 Aug;38(8):835-845. doi: 10.1016/j.tibtech.2020.01.006. Epub 2020 Mar 5. Trends Biotechnol. 2020. PMID: 32673587 Free PMC article. Review.
We propose that these technologies are ready for a new challenge: recapitulating cardiac morphogenesis in vitro. In development, the heart transforms from a simple linear tube to a four-chambered organ through a complex process called looping. Here, we re-examine …
We propose that these technologies are ready for a new challenge: recapitulating cardiac morphogenesis in vitro. In development, the …
Cardiac Morphogenesis: Specification of the Four-Chambered Heart.
Christoffels V, Jensen B. Christoffels V, et al. Cold Spring Harb Perspect Biol. 2020 Oct 1;12(10):a037143. doi: 10.1101/cshperspect.a037143. Cold Spring Harb Perspect Biol. 2020. PMID: 31932321 Free PMC article. Review.
Early heart morphogenesis involves a process in which embryonic precursor cells are instructed to form a cyclic contracting muscle tube connected to blood vessels, pumping fluid. ...Heart morphogenesis, thus, involves the interplay between progressivel …
Early heart morphogenesis involves a process in which embryonic precursor cells are instructed to form a cyclic contracting mu …
Heart fields and cardiac morphogenesis.
Kelly RG, Buckingham ME, Moorman AF. Kelly RG, et al. Cold Spring Harb Perspect Med. 2014 Oct 1;4(10):a015750. doi: 10.1101/cshperspect.a015750. Cold Spring Harb Perspect Med. 2014. PMID: 25274757 Free PMC article. Review.
In this review, we focus on two important steps in the formation of the embryonic heart: (i) the progressive addition of late differentiating progenitor cells from the second heart field that drives heart tube extension during looping morphogenesis, an …
In this review, we focus on two important steps in the formation of the embryonic heart: (i) the progressive addition of late differe …
Cardiac Development and Factors Influencing the Development of Congenital Heart Defects (CHDs): Part I.
Zubrzycki M, Schramm R, Costard-Jäckle A, Grohmann J, Gummert JF, Zubrzycka M. Zubrzycki M, et al. Int J Mol Sci. 2024 Jun 28;25(13):7117. doi: 10.3390/ijms25137117. Int J Mol Sci. 2024. PMID: 39000221 Free PMC article. Review.
Cardiac morphogenesis involves numerous types of cells originating outside the initial cardiac crescent, including neural crest cells, cells of the second heart field origin, and epicardial progenitor cells. ...New techniques for studying heart development ha …
Cardiac morphogenesis involves numerous types of cells originating outside the initial cardiac crescent, including neural crest cells …
Seeking a regulatory roadmap for heart morphogenesis.
Harvey RP. Harvey RP. Semin Cell Dev Biol. 1999 Feb;10(1):99-107. doi: 10.1006/scdb.1998.0277. Semin Cell Dev Biol. 1999. PMID: 10355034 Review.
Despite descriptive studies spanning centuries, we are still lacking an integrated concept of how molecular patterning information is developed in the heart, and how this information guides morphogenesis. With an increasing number of regionally-expressed cardiac gen …
Despite descriptive studies spanning centuries, we are still lacking an integrated concept of how molecular patterning information is develo …
Heart development: molecular insights into cardiac specification and early morphogenesis.
Brand T. Brand T. Dev Biol. 2003 Jun 1;258(1):1-19. doi: 10.1016/s0012-1606(03)00112-x. Dev Biol. 2003. PMID: 12781678 Free article. Review.
The heart develops from two bilateral heart fields that are formed during early gastrulation. ...At the anterior pole, a secondary heart field is formed, which in its molecular make-up, appears to be similar to the primary heart field. ...
The heart develops from two bilateral heart fields that are formed during early gastrulation. ...At the anterior pole, a secon …
Mechanics and function in heart morphogenesis.
Bartman T, Hove J. Bartman T, et al. Dev Dyn. 2005 Jun;233(2):373-81. doi: 10.1002/dvdy.20367. Dev Dyn. 2005. PMID: 15830382 Free article. Review.
For years, biomechanical engineers have studied the physical forces involved in morphogenesis of the heart. In a parallel stream of research, molecular and developmental biologists have sought to identify the molecular pathways responsible for embryonic heart …
For years, biomechanical engineers have studied the physical forces involved in morphogenesis of the heart. In a parallel stre …
Genetics in Congenital Heart Diseases: Unraveling the Link Between Cardiac Morphogenesis, Heart Muscle Disease, and Electrical Disorders.
Baban A, Lodato V, Parlapiano G, Drago F. Baban A, et al. Heart Fail Clin. 2022 Jan;18(1):139-153. doi: 10.1016/j.hfc.2021.07.016. Epub 2021 Oct 26. Heart Fail Clin. 2022. PMID: 34776075 Review.
The genetic background of congenital heart diseases (CHDs) is extremely complex, heterogenous, and still majorly to be determined. ...
The genetic background of congenital heart diseases (CHDs) is extremely complex, heterogenous, and still majorly to be determined. .. …
Heavy and light roles: myosin in the morphogenesis of the heart.
England J, Loughna S. England J, et al. Cell Mol Life Sci. 2013 Apr;70(7):1221-39. doi: 10.1007/s00018-012-1131-1. Epub 2012 Sep 6. Cell Mol Life Sci. 2013. PMID: 22955375 Free PMC article. Review.
Myosins are structural proteins that are not only expressed from early stages of heart development, but when mutated in humans they may give rise to congenital heart defects. This review will discuss the roles of myosin, specifically with regards to the developing …
Myosins are structural proteins that are not only expressed from early stages of heart development, but when mutated in humans they m …
Shape of my heart: Cell-cell adhesion and cytoskeletal dynamics during Drosophila cardiac morphogenesis.
McFaul CMJ, Fernandez-Gonzalez R. McFaul CMJ, et al. Exp Cell Res. 2017 Sep 1;358(1):65-70. doi: 10.1016/j.yexcr.2017.03.057. Epub 2017 Apr 5. Exp Cell Res. 2017. PMID: 28389210 Review.
In addition, the Drosophila embryo is transparent, and thus amenable to time-lapse fluorescence microscopy, as well as biophysical and pharmacological manipulations. One of the conserved aspects of heart development from Drosophila to humans is the initial assembly of a tu …
In addition, the Drosophila embryo is transparent, and thus amenable to time-lapse fluorescence microscopy, as well as biophysical and pharm …
22,276 results
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