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Year Number of Results
2013 1
2015 1
2016 2
2017 1
2018 1
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2020 2
2021 4
2022 5
2023 2
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2026 1

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22 results

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Page 1
Functionally characterizing the renal cell carcinoma tumor immune microenvironment via patient-derived ex vivo models.
Sirc N, Smolander J, Kumari AN, Liu J, Lee MH, Lahdensuo K, Järvinen R, Tornberg SV, Lin L, Laitinen HK, Theodoropoulos J, Klievink J, Mirtti T, Kreutzman AS, Haikala HM, Järvinen P, Mustjoki S, Peltonen K. Sirc N, et al. Among authors: haikala hm. Cancer Res Commun. 2026 Feb 4. doi: 10.1158/2767-9764.CRC-25-0447. Online ahead of print. Cancer Res Commun. 2026. PMID: 41637441 Free article.
Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment.
Alsaed B, Lin L, Son J, Li J, Smolander J, Lopez T, Eser PÖ, Ogino A, Ambrogio C, Eum Y, Thai T, Wang H, Sutinen E, Mutanen H, Duàn H, Bobik N, Borenius K, Feng WW, Nabet B, Mustjoki S, Laaksonen S, Eschle BK, Poitras MJ, Barbie D, Ilonen I, Gokhale P, Jänne PA, Haikala HM. Alsaed B, et al. Among authors: haikala hm. Nat Commun. 2025 Jan 2;16(1):28. doi: 10.1038/s41467-024-55378-5. Nat Commun. 2025. PMID: 39747003 Free PMC article.
Ex vivo modeling of precision immuno-oncology responses in lung cancer.
Alsaed B, Smolander J, Laitinen H, Lin L, Bobik N, Lahtinen L, Räsänen M, Jansouz S, Peltonen K, Jokinen E, Klievink J, Ganesh K, Ainola M, Sutinen E, Rönty M, Narvi E, Thotakura A, Saharinen P, Mustjoki S, Ilonen I, Haikala HM. Alsaed B, et al. Among authors: haikala hm. Sci Adv. 2024 Nov;10(44):eadq6830. doi: 10.1126/sciadv.adq6830. Epub 2024 Oct 30. Sci Adv. 2024. PMID: 39475596 Free PMC article.
An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer.
To C, Beyett TS, Jang J, Feng WW, Bahcall M, Haikala HM, Shin BH, Heppner DE, Rana JK, Leeper BA, Soroko KM, Poitras MJ, Gokhale PC, Kobayashi Y, Wahid K, Kurppa KJ, Gero TW, Cameron MD, Ogino A, Mushajiang M, Xu C, Zhang Y, Scott DA, Eck MJ, Gray NS, Jänne PA. To C, et al. Among authors: haikala hm. Nat Cancer. 2022 Apr;3(4):402-417. doi: 10.1038/s43018-022-00351-8. Epub 2022 Apr 14. Nat Cancer. 2022. PMID: 35422503 Free PMC article.
Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non-Small Cell Lung Cancer.
Ricciuti B, Son J, Okoro JJ, Mira A, Patrucco E, Eum Y, Wang X, Paranal R, Wang H, Lin M, Haikala HM, Li J, Xu Y, Alessi JV, Chhoeu C, Redig AJ, Köhler J, Dholakia KH, Chen Y, Richard E, Nokin MJ, Santamaria D, Gokhale PC, Awad MM, Jänne PA, Ambrogio C. Ricciuti B, et al. Among authors: haikala hm. Clin Cancer Res. 2022 Apr 14;28(8):1640-1650. doi: 10.1158/1078-0432.CCR-21-2719. Clin Cancer Res. 2022. PMID: 35091439 Free PMC article.
Sortilin-related receptor is a druggable therapeutic target in breast cancer.
Al-Akhrass H, Pietilä M, Lilja J, Vesilahti EM, Anttila JM, Haikala HM, Munne PM, Klefström J, Peuhu E, Ivaska J. Al-Akhrass H, et al. Among authors: haikala hm. Mol Oncol. 2022 Jan;16(1):116-129. doi: 10.1002/1878-0261.13106. Epub 2021 Oct 10. Mol Oncol. 2022. PMID: 34564954 Free PMC article.
22 results