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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 6
2000 2
2001 4
2002 1
2003 3
2004 2
2005 4
2006 4
2007 5
2008 5
2009 7
2010 4
2011 3
2012 4
2013 7
2014 6
2015 9
2016 8
2017 13
2018 14
2019 12
2020 5
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116 results
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The aliens inside us: HERV-W endogenous retroviruses and multiple sclerosis.
Dolei A. Dolei A. Mult Scler. 2018 Jan;24(1):42-47. doi: 10.1177/1352458517737370. Mult Scler. 2018. PMID: 29307292 Review.
Two human endogenous retroviruses of the HERV-W family are proposed as multiple sclerosis (MS) co-factors: MS-associated retrovirus (MSRV) and ERVWE1, whose env proteins showed several potentially neuropathogenic features, in vitro and in animal models …
Two human endogenous retroviruses of the HERV-W family are proposed as multiple sclerosis (MS) co-factors: MS-as …
Antibody response against HERV-W in patients with MOG-IgG associated disorders, multiple sclerosis and NMOSD.
Arru G, Sechi E, Mariotto S, Zarbo IR, Ferrari S, Gajofatto A, Monaco S, Deiana GA, Bo M, Sechi LA, Sechi GP. Arru G, et al. J Neuroimmunol. 2020 Jan 15;338:577110. doi: 10.1016/j.jneuroim.2019.577110. Epub 2019 Nov 6. J Neuroimmunol. 2020. PMID: 31715457
Increased expression of the retroviruses of HERV-W family has been linked to multiple sclerosis (MS) pathophysiology; nothing is known at the moment about MOG-IgG associated disorders. We compared antibody response against HERV-W peptides …
Increased expression of the retroviruses of HERV-W family has been linked to multiple sclerosis (MS) pathophysio …
On the origin of a pathogenic HERV-W envelope protein present in multiple sclerosis lesions.
Ruprecht K, Mayer J. Ruprecht K, et al. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19791-19792. doi: 10.1073/pnas.1911703116. Epub 2019 Aug 27. Proc Natl Acad Sci U S A. 2019. PMID: 31455746 Free PMC article. No abstract available.
Do Human Endogenous Retroviruses Contribute to Multiple Sclerosis, and if So, How?
Morris G, Maes M, Murdjeva M, Puri BK. Morris G, et al. Mol Neurobiol. 2019 Apr;56(4):2590-2605. doi: 10.1007/s12035-018-1255-x. Epub 2018 Jul 25. Mol Neurobiol. 2019. PMID: 30047100 Free PMC article. Review.
The gammaretroviral human endogenous retrovirus (HERV) families MRSV/HERV-W and HERV-H (including the closely related HERV-Fc1) are associated with an increased risk of multiple sclerosis (MS). ...Furthermore, some HERV-asso …
The gammaretroviral human endogenous retrovirus (HERV) families MRSV/HERV-W and HERV-H (including the closely re …
pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis.
Kremer D, Gruchot J, Weyers V, Oldemeier L, Göttle P, Healy L, Ho Jang J, Kang T Xu Y, Volsko C, Dutta R, Trapp BD, Perron H, Hartung HP, Küry P. Kremer D, et al. Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15216-15225. doi: 10.1073/pnas.1901283116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213545 Free PMC article.
Axonal degeneration is central to clinical disability and disease progression in multiple sclerosis (MS). Myeloid cells such as brain-resident microglia and blood-borne monocytes are thought to be critically involved in this degenerative process. ...We have previous …
Axonal degeneration is central to clinical disability and disease progression in multiple sclerosis (MS). Myeloid cells such a …
Humoral immunity response to human endogenous retroviruses K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases.
Arru G, Mameli G, Deiana GA, Rassu AL, Piredda R, Sechi E, Caggiu E, Bo M, Nako E, Urso D, Mariotto S, Ferrari S, Zanusso G, Monaco S, Sechi G, Sechi LA. Arru G, et al. Eur J Neurol. 2018 Aug;25(8):1076-e84. doi: 10.1111/ene.13648. Epub 2018 May 14. Eur J Neurol. 2018. PMID: 29603839
BACKGROUND AND PURPOSE: Human endogenous retroviruses (HERV) K/W seem to play a role in fostering and exacerbation of some neurological diseases, including amyotrophic lateral sclerosis (ALS). Given these findings, the immunity response against HERV-K …
BACKGROUND AND PURPOSE: Human endogenous retroviruses (HERV) K/W seem to play a role in fostering and exacerbation of some neu …
Antibody response against HERV-W env surface peptides differentiates multiple sclerosis and neuromyelitis optica spectrum disorder.
Arru G, Sechi E, Mariotto S, Farinazzo A, Mancinelli C, Alberti D, Ferrari S, Gajofatto A, Capra R, Monaco S, Deiana GA, Caggiu E, Mameli G, Sechi LA, Sechi GP. Arru G, et al. Mult Scler J Exp Transl Clin. 2017 Nov 22;3(4):2055217317742425. doi: 10.1177/2055217317742425. eCollection 2017 Oct-Dec. Mult Scler J Exp Transl Clin. 2017. PMID: 29204291 Free PMC article.
BACKGROUND: A specific humoral immune response against HERV-W envelope surface (env-su) glycoprotein antigens has been reported in serum of patients with multiple sclerosis (MS). ...Thus, the specific humoral immune response against HERV-W
BACKGROUND: A specific humoral immune response against HERV-W envelope surface (env-su) glycoprotein antigens has been reporte …
Human Endogenous Retroviruses in Neurological Diseases.
Küry P, Nath A, Créange A, Dolei A, Marche P, Gold J, Giovannoni G, Hartung HP, Perron H. Küry P, et al. Trends Mol Med. 2018 Apr;24(4):379-394. doi: 10.1016/j.molmed.2018.02.007. Epub 2018 Mar 15. Trends Mol Med. 2018. PMID: 29551251 Free PMC article. Review.
The causes of multiple sclerosis and amyotrophic lateral sclerosis have long remained elusive. A new category of pathogenic components, normally dormant within human genomes, has been identified: human endogenous retroviruses (HERVs). ...The resulting product …
The causes of multiple sclerosis and amyotrophic lateral sclerosis have long remained elusive. A new category of pathog …
Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement.
Charvet B, Reynaud JM, Gourru-Lesimple G, Perron H, Marche PN, Horvat B. Charvet B, et al. Front Immunol. 2018 Dec 6;9:2803. doi: 10.3389/fimmu.2018.02803. eCollection 2018. Front Immunol. 2018. PMID: 30574140 Free PMC article.
The aberrant expression of human endogenous retrovirus (HERV) elements of the HERV-W family has been associated with different diseases, including multiple sclerosis (MS). In particular, the expression of the envelope protein (Env) from the m
The aberrant expression of human endogenous retrovirus (HERV) elements of the HERV-W family has been associated with di …
Do Antiretroviral Drugs Protect From Multiple Sclerosis by Inhibiting Expression of MS-Associated Retrovirus?
Morandi E, Tanasescu R, Tarlinton RE, Constantin-Teodosiu D, Gran B. Morandi E, et al. Front Immunol. 2019 Jan 22;9:3092. doi: 10.3389/fimmu.2018.03092. eCollection 2018. Front Immunol. 2019. PMID: 30740110 Free PMC article. Clinical Trial.
The expression of human endogenous retroviruses (HERVs) has been associated with Multiple Sclerosis (MS). The MS-related retrovirus (MSRV/HERV-W) has the potential to activate inflammatory immunity, which could promote both susceptibility and progressi …
The expression of human endogenous retroviruses (HERVs) has been associated with Multiple Sclerosis (MS). The MS-related retro …
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