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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2004 1
2005 1
2006 2
2007 2
2008 4
2009 1
2010 2
2011 3
2012 2
2013 4
2014 1
2015 2
2016 7
2017 5
2018 3
2019 3
2021 4
2022 1
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Page 1
Pathophysiological Role of HERV-W in Schizophrenia.
Aftab A, Shah AA, Hashmi AM. Aftab A, et al. J Neuropsychiatry Clin Neurosci. 2016 Winter;28(1):17-25. doi: 10.1176/appi.neuropsych.15030059. Epub 2015 Sep 25. J Neuropsychiatry Clin Neurosci. 2016. PMID: 26404170 Review.
Studies have identified retroviral nucleotide sequences, envelope and capsid proteins, and elevated transcription of HERV-W elements in CSF, blood, and brain samples from individuals with schizophrenia. The HERV-W elements can trigger the immune …
Studies have identified retroviral nucleotide sequences, envelope and capsid proteins, and elevated transcription of HERV-W el …
Human endogenous retrovirus type W (HERV-W) in schizophrenia: a new avenue of research at the gene-environment interface.
Leboyer M, Tamouza R, Charron D, Faucard R, Perron H. Leboyer M, et al. World J Biol Psychiatry. 2013 Mar;14(2):80-90. doi: 10.3109/15622975.2010.601760. Epub 2011 Sep 22. World J Biol Psychiatry. 2013. PMID: 21936762 Review.
OBJECTIVES: Provide a synthetic review of recent studies evidencing an association between human endogenous retrovirus-W (HERV-W) and schizophrenia. METHODS: Bibliography analysis and contextual synthesis. ...Elevated transcription of HERV-W
OBJECTIVES: Provide a synthetic review of recent studies evidencing an association between human endogenous retrovirus-W (HERV
Identification of inflammatory subgroups of schizophrenia and bipolar disorder patients with HERV-W ENV antigenemia by unsupervised cluster analysis.
Tamouza R, Meyer U, Foiselle M, Richard JR, Wu CL, Boukouaci W, Le Corvoisier P, Barrau C, Lucas A, Perron H, Leboyer M. Tamouza R, et al. Transl Psychiatry. 2021 Jul 6;11(1):377. doi: 10.1038/s41398-021-01499-0. Transl Psychiatry. 2021. PMID: 34230451 Free PMC article.
Human endogenous retroviruses (HERVs) are remnants of infections that took place several million years ago and represent around 8% of the human genome. Despite evidence implicating increased expression of HERV type W envelope (HERV-W ENV) in schizop
Human endogenous retroviruses (HERVs) are remnants of infections that took place several million years ago and represent around 8% of the hu …
HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk.
Yan Q, Wu X, Zhou P, Zhou Y, Li X, Liu Z, Tan H, Yao W, Xia Y, Zhu F. Yan Q, et al. Viruses. 2022 Jan 14;14(1):145. doi: 10.3390/v14010145. Viruses. 2022. PMID: 35062349 Free PMC article.
An increasing number of studies have begun considering human endogenous retroviruses (HERVs) as potential pathogenic phenomena. Our previous research suggests that HERV-W Envelope (HERV-W ENV), a HERV-W family envelope protein, is elevate …
An increasing number of studies have begun considering human endogenous retroviruses (HERVs) as potential pathogenic phenomena. Our previous …
Human endogenous retrovirus W family envelope protein (HERV-W env) facilitates the production of TNF-α and IL-10 by inhibiting MyD88s in glial cells.
Wang X, Wu X, Huang J, Li H, Yan Q, Zhu F. Wang X, et al. Arch Virol. 2021 Apr;166(4):1035-1045. doi: 10.1007/s00705-020-04933-8. Epub 2021 Jan 12. Arch Virol. 2021. PMID: 33438105
Human endogenous retrovirus W family envelope protein (HERV-W env) is associated with several neurological and psychiatric disorders, including multiple sclerosis (MS) and schizophrenia. ...HERV-W env also induced a notable increase in To …
Human endogenous retrovirus W family envelope protein (HERV-W env) is associated with several neurological and psychiat …
HERV-W env regulates calcium influx via activating TRPC3 channel together with depressing DISC1 in human neuroblastoma cells.
Chen Y, Yan Q, Zhou P, Li S, Zhu F. Chen Y, et al. J Neurovirol. 2019 Feb;25(1):101-113. doi: 10.1007/s13365-018-0692-7. Epub 2018 Nov 5. J Neurovirol. 2019. PMID: 30397826
In the present study, we aimed to elucidate the relationship between HERV-W env and calcium signaling in schizophrenia. Our results showed that HERV-W env could induce Ca(2+) influx in two human neuroblastoma cell lines and upregulate the expres …
In the present study, we aimed to elucidate the relationship between HERV-W env and calcium signaling in schizophrenia. …
GABBR1 has a HERV-W LTR in its regulatory region--a possible implication for schizophrenia.
Hegyi H. Hegyi H. Biol Direct. 2013 Feb 7;8:5. doi: 10.1186/1745-6150-8-5. Biol Direct. 2013. PMID: 23391219 Free PMC article.
Schizophrenia is a complex disease with uncertain aetiology. We suggest GABBR1, GABA receptor B1 implicated in schizophrenia based on a HERV-W LTR in the regulatory region of GABBR1. Our hypothesis is supported by: (i) GABBR1 is in the 6p22 genomic reg
Schizophrenia is a complex disease with uncertain aetiology. We suggest GABBR1, GABA receptor B1 implicated in schizophrenia b
HERVs in neuropathogenesis.
Christensen T. Christensen T. J Neuroimmune Pharmacol. 2010 Sep;5(3):326-35. doi: 10.1007/s11481-010-9214-y. Epub 2010 Apr 27. J Neuroimmune Pharmacol. 2010. PMID: 20422298 Review.
New reports show that IFN-beta also mediate down-regulation of HERV-H/F and HERV-W in MS patients. HERV-W and HERV-K transcription (gag and pol) appears, to some extent, to be up-regulated in the circulation and the CNS of patients with …
New reports show that IFN-beta also mediate down-regulation of HERV-H/F and HERV-W in MS patients. HERV-W
Activation of elements in HERV-W family by caffeine and aspirin.
Liu C, Chen Y, Li S, Yu H, Zeng J, Wang X, Zhu F. Liu C, et al. Virus Genes. 2013 Oct;47(2):219-27. doi: 10.1007/s11262-013-0939-6. Epub 2013 Jun 28. Virus Genes. 2013. PMID: 23813246
Western blotting was used to detect the protein of HERV-W env. Luciferase activity assay was employed to detect the activity of HERV-W env promoter. It was found that both caffeine and aspirin could increase the expression of HERV-W env a …
Western blotting was used to detect the protein of HERV-W env. Luciferase activity assay was employed to detect the activity o …
40 results