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10,942 results

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Page 1
Heterocyclic NO prodrugs.
Schönafinger K. Schönafinger K. Farmaco. 1999 May 30;54(5):316-20. doi: 10.1016/s0014-827x(99)00031-2. Farmaco. 1999. PMID: 10418124 Review.
An overview of the different heterocyclic NO-releasing compounds is given. Mesoionic heterocycles like sydnone imines are one example. ...Furthermore, 1,2,3,4 oxatriazolium olates and imidates are presented in an example of the synthesis of GEA-3175. Heterocyclic …
An overview of the different heterocyclic NO-releasing compounds is given. Mesoionic heterocycles like sydnone imines are one …
Heterocyclic Hemipiperazines: Water-Compatible Peptide-Derived Photoswitches.
Gödtel P, Starrett J, Pianowski ZL. Gödtel P, et al. Chemistry. 2023 May 8;29(26):e202204009. doi: 10.1002/chem.202204009. Epub 2023 Mar 23. Chemistry. 2023. PMID: 36790823
Here, for the first time we describe photochromism of heterocyclic hemipiperazines. They demonstrate long thermal lifetimes, and enlarged band separation between photoisomers. ...
Here, for the first time we describe photochromism of heterocyclic hemipiperazines. They demonstrate long thermal lifetimes, and enla …
2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potentiates nitrosation of a heterocyclic amine carcinogen by nitric oxide.
Lakshmi VM, Zenser TV. Lakshmi VM, et al. Life Sci. 2007 Jan 23;80(7):644-9. doi: 10.1016/j.lfs.2006.10.010. Epub 2006 Nov 28. Life Sci. 2007. PMID: 17129590
Although nitrosation plays an important role in initiation of carcinogenesis, the reactive nitrogen oxygen species (RNOS) mediating this reaction by multiple pathways have not been determined. The heterocyclic amine carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) w …
Although nitrosation plays an important role in initiation of carcinogenesis, the reactive nitrogen oxygen species (RNOS) mediating this rea …
Heterocyclic effect boosted peroxidase-like activity of MIL(Fe) metal-organic framework for colorimetric assay and dye removal.
Ma D, Li N, Zhu D, Li F. Ma D, et al. J Hazard Mater. 2024 Dec 5;480:136148. doi: 10.1016/j.jhazmat.2024.136148. Epub 2024 Oct 11. J Hazard Mater. 2024. PMID: 39405683
Accordingly, FeTDC can facilitate the oxidation of the benzidine substrate in the presence of H(2)O(2), thereby exhibiting remarkable peroxidase-like activity. ...This work presents a novel perspective of heterocyclic effect on the design of MOF nanozymes, thereby e …
Accordingly, FeTDC can facilitate the oxidation of the benzidine substrate in the presence of H(2)O(2), thereby exhibiting remarkable …
Hydride-Abstraction-Initiated Catalytic Stereoselective Intermolecular Bond-Forming Processes.
Liu L. Liu L. Acc Chem Res. 2022 Dec 6;55(23):3537-3550. doi: 10.1021/acs.accounts.2c00638. Epub 2022 Nov 17. Acc Chem Res. 2022. PMID: 36384272
In particular, developing such a stereoselective bimolecular transformation involving carbocation intermediates generated via site-selective hydride abstraction or formal hydride abstraction by organic oxidants would avoid the preinstallation of directing groups and is the …
In particular, developing such a stereoselective bimolecular transformation involving carbocation intermediates generated via site-selective …
Phosphine Oxide Indenoquinoline Derivatives: Synthesis and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative Agents.
Rodriguez-Paniagua A, Tesauro C, Knudsen BR, Fuertes M, Alonso C. Rodriguez-Paniagua A, et al. Molecules. 2024 Dec 19;29(24):5992. doi: 10.3390/molecules29245992. Molecules. 2024. PMID: 39770084 Free PMC article.
Subsequent oxidation of the methylene present in the structure resulted in the corresponding indeno[2,1-c]quinolin-7-one phosphine oxides 10. ...These results represent a very interesting advance since the heterocyclic phosphine oxide derivatives have …
Subsequent oxidation of the methylene present in the structure resulted in the corresponding indeno[2,1-c]quinolin-7-one phosphine …
Click and Bio-Orthogonal Reactions with Mesoionic Compounds.
Porte K, Riomet M, Figliola C, Audisio D, Taran F. Porte K, et al. Chem Rev. 2021 Jun 23;121(12):6718-6743. doi: 10.1021/acs.chemrev.0c00806. Epub 2020 Nov 25. Chem Rev. 2021. PMID: 33238101 Review.
Among the dipoles routinely used for click chemistry, azides, nitrones, isonitriles, and nitrile oxides are the most popular. This review is focused on the emerging click chemistry that uses mesoionic compounds as dipole partners. ...This review covers the synthetic access …
Among the dipoles routinely used for click chemistry, azides, nitrones, isonitriles, and nitrile oxides are the most popular. This re …
Polymerization of Ethylene Oxide, Propylene Oxide, and Other Alkylene Oxides: Synthesis, Novel Polymer Architectures, and Bioconjugation.
Herzberger J, Niederer K, Pohlit H, Seiwert J, Worm M, Wurm FR, Frey H. Herzberger J, et al. Chem Rev. 2016 Feb 24;116(4):2170-243. doi: 10.1021/acs.chemrev.5b00441. Epub 2015 Dec 29. Chem Rev. 2016. PMID: 26713458 Free article. Review.
The review summarizes current trends and developments in the polymerization of alkylene oxides in the last two decades since 1995, with a particular focus on the most important epoxide monomers ethylene oxide (EO), propylene oxide (PO), and butylene oxide …
The review summarizes current trends and developments in the polymerization of alkylene oxides in the last two decades since 1995, wi …
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