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1947 1
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1961 4
1962 7
1963 11
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1965 6
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1967 12
1968 24
1969 16
1970 16
1971 7
1972 23
1973 13
1974 10
1975 10
1976 8
1977 10
1978 11
1979 12
1980 10
1981 10
1982 10
1983 10
1984 22
1985 21
1986 20
1987 30
1988 29
1989 45
1990 38
1991 38
1992 59
1993 41
1994 57
1995 49
1996 66
1997 66
1998 57
1999 81
2000 100
2001 132
2002 147
2003 182
2004 190
2005 238
2006 233
2007 282
2008 285
2009 325
2010 335
2011 392
2012 408
2013 439
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2015 548
2016 509
2017 509
2018 540
2019 539
2020 580
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11,041 results

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Page 1
Heterocyclic Hemipiperazines: Water-Compatible Peptide-Derived Photoswitches.
Gödtel P, Starrett J, Pianowski ZL. Gödtel P, et al. Chemistry. 2023 May 8;29(26):e202204009. doi: 10.1002/chem.202204009. Epub 2023 Mar 23. Chemistry. 2023. PMID: 36790823
Here, for the first time we describe photochromism of heterocyclic hemipiperazines. They demonstrate long thermal lifetimes, and enlarged band separation between photoisomers. ...
Here, for the first time we describe photochromism of heterocyclic hemipiperazines. They demonstrate long thermal lifetimes, and enla …
Heterocyclic NO prodrugs.
Schönafinger K. Schönafinger K. Farmaco. 1999 May 30;54(5):316-20. doi: 10.1016/s0014-827x(99)00031-2. Farmaco. 1999. PMID: 10418124 Review.
An overview of the different heterocyclic NO-releasing compounds is given. Mesoionic heterocycles like sydnone imines are one example. ...Furthermore, 1,2,3,4 oxatriazolium olates and imidates are presented in an example of the synthesis of GEA-3175. Heterocyclic …
An overview of the different heterocyclic NO-releasing compounds is given. Mesoionic heterocycles like sydnone imines are one …
Hydride-Abstraction-Initiated Catalytic Stereoselective Intermolecular Bond-Forming Processes.
Liu L. Liu L. Acc Chem Res. 2022 Dec 6;55(23):3537-3550. doi: 10.1021/acs.accounts.2c00638. Epub 2022 Nov 17. Acc Chem Res. 2022. PMID: 36384272
In particular, developing such a stereoselective bimolecular transformation involving carbocation intermediates generated via site-selective hydride abstraction or formal hydride abstraction by organic oxidants would avoid the preinstallation of directing groups and is the …
In particular, developing such a stereoselective bimolecular transformation involving carbocation intermediates generated via site-selective …
2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potentiates nitrosation of a heterocyclic amine carcinogen by nitric oxide.
Lakshmi VM, Zenser TV. Lakshmi VM, et al. Life Sci. 2007 Jan 23;80(7):644-9. doi: 10.1016/j.lfs.2006.10.010. Epub 2006 Nov 28. Life Sci. 2007. PMID: 17129590
Although nitrosation plays an important role in initiation of carcinogenesis, the reactive nitrogen oxygen species (RNOS) mediating this reaction by multiple pathways have not been determined. The heterocyclic amine carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) w …
Although nitrosation plays an important role in initiation of carcinogenesis, the reactive nitrogen oxygen species (RNOS) mediating this rea …
Click and Bio-Orthogonal Reactions with Mesoionic Compounds.
Porte K, Riomet M, Figliola C, Audisio D, Taran F. Porte K, et al. Chem Rev. 2021 Jun 23;121(12):6718-6743. doi: 10.1021/acs.chemrev.0c00806. Epub 2020 Nov 25. Chem Rev. 2021. PMID: 33238101 Review.
Among the dipoles routinely used for click chemistry, azides, nitrones, isonitriles, and nitrile oxides are the most popular. This review is focused on the emerging click chemistry that uses mesoionic compounds as dipole partners. ...This review covers the synthetic access …
Among the dipoles routinely used for click chemistry, azides, nitrones, isonitriles, and nitrile oxides are the most popular. This re …
Synthesis of Lactones and Other Heterocycles.
Liu X, He LN. Liu X, et al. Top Curr Chem (Cham). 2017 Apr;375(2):21. doi: 10.1007/s41061-017-0108-9. Epub 2017 Feb 6. Top Curr Chem (Cham). 2017. PMID: 28168646 Review.
In this aspect, the construction of heterocyclic compounds from CO(2) and readily available starting materials is particularly appealing in both organic and pharmaceutical fields since CO(2) can be regarded as carbon and oxygen resource with advantages of abundance, renewa …
In this aspect, the construction of heterocyclic compounds from CO(2) and readily available starting materials is particularly appeal …
[3-Methylpyridazine N-oxide].
NAKAGOME T. NAKAGOME T. Yakugaku Zasshi. 1961 Dec;81:1817. doi: 10.1248/yakushi1947.81.12_1817. Yakugaku Zasshi. 1961. PMID: 14478092 Japanese. No abstract available.
Phosphine Oxide Indenoquinoline Derivatives: Synthesis and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative Agents.
Rodriguez-Paniagua A, Tesauro C, Knudsen BR, Fuertes M, Alonso C. Rodriguez-Paniagua A, et al. Molecules. 2024 Dec 19;29(24):5992. doi: 10.3390/molecules29245992. Molecules. 2024. PMID: 39770084 Free PMC article.
Subsequent oxidation of the methylene present in the structure resulted in the corresponding indeno[2,1-c]quinolin-7-one phosphine oxides 10. ...These results represent a very interesting advance since the heterocyclic phosphine oxide derivatives have …
Subsequent oxidation of the methylene present in the structure resulted in the corresponding indeno[2,1-c]quinolin-7-one phosphine …
11,041 results
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