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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 1
1975 2
1976 3
1978 4
1979 3
1980 4
1981 2
1982 3
1983 1
1984 4
1985 5
1986 7
1987 3
1988 4
1989 6
1990 5
1991 11
1992 10
1993 13
1994 24
1995 34
1996 72
1997 132
1998 213
1999 277
2000 335
2001 389
2002 402
2003 425
2004 460
2005 509
2006 589
2007 610
2008 598
2009 577
2010 565
2011 594
2012 582
2013 590
2014 569
2015 518
2016 558
2017 553
2018 515
2019 512
2020 538
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2022 364
2023 331
2024 377
2025 480
2026 300

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12,793 results

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Page 1
The histone acetyltransferase GCN5 regulates floral meristem activity and flower development in Arabidopsis.
Hawar A, Chen W, Zhu T, Wang X, Liu J, Xiong S, Ito T, Chen D, Sun B. Hawar A, et al. Plant Cell. 2025 Jun 4;37(6):koaf135. doi: 10.1093/plcell/koaf135. Plant Cell. 2025. PMID: 40413778 Free article.
The histone acetyltransferase (HAT) GENERAL CONTROL NON DEREPRESSIBLE5 (GCN5) participates in various developmental processes in Arabidopsis (Arabidopsis thaliana). ...Here, we show that during early flower development, GCN5 catalyzes histone acetylation at W …
The histone acetyltransferase (HAT) GENERAL CONTROL NON DEREPRESSIBLE5 (GCN5) participates in various developmental processes …
Histone acetyltransferase inhibitors: An overview in synthesis, structure-activity relationship and molecular mechanism.
Huang M, Huang J, Zheng Y, Sun Q. Huang M, et al. Eur J Med Chem. 2019 Sep 15;178:259-286. doi: 10.1016/j.ejmech.2019.05.078. Epub 2019 May 31. Eur J Med Chem. 2019. PMID: 31195169 Review.
Here, we summarized three classes of HAT inhibitors based on their sources and structural scaffolds, emphasizing on their synthetic methods and structure-activity relationships and molecular mechanisms, hoping to facilitate the development and further application of HAT in …
Here, we summarized three classes of HAT inhibitors based on their sources and structural scaffolds, emphasizing on their synthetic methods …
Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.
Yang G, Yuan Y, Yuan H, Wang J, Yun H, Geng Y, Zhao M, Li L, Weng Y, Liu Z, Feng J, Bu Y, Liu L, Wang B, Zhang X. Yang G, et al. EMBO Rep. 2021 Feb 3;22(2):e50967. doi: 10.15252/embr.202050967. Epub 2020 Dec 29. EMBO Rep. 2021. PMID: 33372411 Free PMC article.
Lysine succinylation (Ksucc) is an evolutionarily conserved and widespread post-translational modification. Histone acetyltransferase 1 (HAT1) is a type B histone acetyltransferase, regulating the acetylation of both histone and non-histone
Lysine succinylation (Ksucc) is an evolutionarily conserved and widespread post-translational modification. Histone acetyltransfer
Histone acetyltransferase 1 promotes postinfarction inflammatory response by regulation of monocyte histone succinylation.
Guo Y, Xiong J, Li Z, Bai L, Wang B, Guo B, Tang H, Li G, Qiu Y, Lv L, Dong Z, Tu Y. Guo Y, et al. Nat Commun. 2025 Nov 28;16(1):11718. doi: 10.1038/s41467-025-66721-9. Nat Commun. 2025. PMID: 41315268 Free PMC article.
Early activation and phenotypic transformation of monocytes and macrophages are essential for inflammatory activities and tissue repair following myocardial infarction (MI). ...We further reveal that histone acetyltransferase 1 (Hat1) acts as a succiny …
Early activation and phenotypic transformation of monocytes and macrophages are essential for inflammatory activities and tiss …
Gcn5: The quintessential histone acetyltransferase.
Weake VM. Weake VM. Biochim Biophys Acta Gene Regul Mech. 2021 Feb;1864(2):194658. doi: 10.1016/j.bbagrm.2020.194658. Epub 2020 Nov 21. Biochim Biophys Acta Gene Regul Mech. 2021. PMID: 33248929 No abstract available.
The Ada2/Ada3/Gcn5/Sgf29 histone acetyltransferase module.
Espinola-Lopez JM, Tan S. Espinola-Lopez JM, et al. Biochim Biophys Acta Gene Regul Mech. 2021 Feb;1864(2):194629. doi: 10.1016/j.bbagrm.2020.194629. Epub 2020 Sep 2. Biochim Biophys Acta Gene Regul Mech. 2021. PMID: 32890768 Free PMC article. Review.
Gcn5 (KAT2A) is a histone acetyltransferase that catalyzes the post-translational modification at multiple positions of histone H3 through the transfer of acetyl groups to the free amino group of lysine residues. ...Biochemical and structural studies have elu …
Gcn5 (KAT2A) is a histone acetyltransferase that catalyzes the post-translational modification at multiple positions of his
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents.
Chen Q, Yang B, Liu X, Zhang XD, Zhang L, Liu T. Chen Q, et al. Theranostics. 2022 Jun 21;12(11):4935-4948. doi: 10.7150/thno.73223. eCollection 2022. Theranostics. 2022. PMID: 35836809 Free PMC article. Review.
The histone acetyltransferases CBP and p300, often referred to as CBP/p300 due to their sequence homology and functional overlap and co-operation, are emerging as critical drivers of oncogenesis in the past several years. ...Small molecule CBP/p300 histone
The histone acetyltransferases CBP and p300, often referred to as CBP/p300 due to their sequence homology and functional overl …
Structure of the NuA4 histone acetyltransferase complex.
Ji L, Zhao L, Xu K, Gao H, Zhou Y, Kornberg RD, Zhang H. Ji L, et al. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2214313119. doi: 10.1073/pnas.2214313119. Epub 2022 Nov 22. Proc Natl Acad Sci U S A. 2022. PMID: 36417436 Free PMC article.
Nucleosome acetyltransferase of H4 (NuA4), one of two major histone acetyltransferase complexes in Saccharomyces cerevisiae specifically acetylates histone H2A and H4, resulting in increased transcriptional activity. ...Biochemical studies showe …
Nucleosome acetyltransferase of H4 (NuA4), one of two major histone acetyltransferase complexes in Saccharomyces cerevi …
Histone acetyltransferase 1: more than just an enzyme?
Parthun MR. Parthun MR. Biochim Biophys Acta. 2012 Mar-Apr;1819(3-4):256-63. doi: 10.1016/j.bbagrm.2011.07.006. Epub 2011 Jul 18. Biochim Biophys Acta. 2012. PMID: 24459728 Free PMC article. Review.
Histone acetyltransferase 1 (HAT1) is an enzyme that is likely to be responsible for the acetylation that occurs on lysines 5 and 12 of the NH2-terminal tail of newly synthesized histone H4. ...Surprisingly, the function of HAT1 in chromatin assembly may exte
Histone acetyltransferase 1 (HAT1) is an enzyme that is likely to be responsible for the acetylation that occurs on lysines 5
Intrinsic ubiquitin E3 ligase activity of histone acetyltransferase Hbo1 for estrogen receptor alpha.
Iizuka M, Susa T, Tamamori-Adachi M, Okinaga H, Okazaki T. Iizuka M, et al. Proc Jpn Acad Ser B Phys Biol Sci. 2017;93(7):498-510. doi: 10.2183/pjab.93.030. Proc Jpn Acad Ser B Phys Biol Sci. 2017. PMID: 28769019 Free PMC article.
Indeed, several transcriptional coactivators for ER-dependent transcription ubiquitinate ER. Histone acetyltransferase (HAT) Hbo1/KAT7/MYST2, involved in global histone acetylation, DNA replication, transcription, and cellular proliferation, promotes proteaso …
Indeed, several transcriptional coactivators for ER-dependent transcription ubiquitinate ER. Histone acetyltransferase (HAT) H …
12,793 results
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