Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1986 1
1988 1
1989 1
1991 6
1992 1
1993 2
1994 2
1995 5
1996 1
1997 2
1998 2
1999 7
2000 2
2001 3
2002 8
2003 6
2004 15
2005 18
2006 8
2007 12
2008 14
2009 14
2010 18
2011 24
2012 17
2013 19
2014 17
2015 15
2016 10
2017 15
2018 7
2019 10
2020 10
2021 17
2022 13
2023 9
2024 11
2025 8
2026 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

306 results

Results by year

Filters applied: . Clear all
Page 1
Biotin: From Nutrition to Therapeutics.
Mock DM. Mock DM. J Nutr. 2017 Aug;147(8):1487-1492. doi: 10.3945/jn.116.238956. Epub 2017 Jul 12. J Nutr. 2017. PMID: 28701385 Free PMC article. Review.
Herein I review 1) advances in assessing biotin status, including the relation between acylcarnitine excretion and biotin status; 2) recent studies of biotin status in pregnancy; 3) advances in understanding the role of biotin in gene expression and the potential roles of biot …
Herein I review 1) advances in assessing biotin status, including the relation between acylcarnitine excretion and biotin status; 2) recent …
A novel, enigmatic histone modification: biotinylation of histones by holocarboxylase synthetase.
Hassan YI, Zempleni J. Hassan YI, et al. Nutr Rev. 2008 Dec;66(12):721-5. doi: 10.1111/j.1753-4887.2008.00127.x. Nutr Rev. 2008. PMID: 19019041 Review.
About 30% of the histone H4 molecules are biotinylated at K12 in histone H4 in human fibroblast telomeres. The abundance of biotinylated histones at distinct genomic loci depends on biotin availability. Decreased histone biotinylation …
About 30% of the histone H4 molecules are biotinylated at K12 in histone H4 in human fibroblast telomeres. The abundanc …
Histone biotinylation in Candida albicans.
Hasim S, Tati S, Madayiputhiya N, Nandakumar R, Nickerson KW. Hasim S, et al. FEMS Yeast Res. 2013 Sep;13(6):529-39. doi: 10.1111/1567-1364.12056. Epub 2013 Jun 25. FEMS Yeast Res. 2013. PMID: 23718707 Free article.
Roughly, equivalent levels of acetylation, methylation, and phosphorylation were found in histones from biotin-replete and biotin-starved cells, but histone biotinylation was only observed for cells grown in excess biotin. ...Techniques used to detect hist …
Roughly, equivalent levels of acetylation, methylation, and phosphorylation were found in histones from biotin-replete and biotin-sta …
Nonenzymatic biotinylation of histone H2A.
Healy S, Heightman TD, Hohmann L, Schriemer D, Gravel RA. Healy S, et al. Protein Sci. 2009 Feb;18(2):314-28. doi: 10.1002/pro.37. Protein Sci. 2009. PMID: 19160459 Free PMC article.
The specific attachment sites of nonenzymatically biotinylated recombinant H2A at different time points were identified using mass spectrometry, and were found to consist of a similar pattern of biotin attachment as seen in the presence of HCS, with preference for lysines …
The specific attachment sites of nonenzymatically biotinylated recombinant H2A at different time points were identified using mass sp …
Biotinylation of lysine 16 in histone H4 contributes toward nucleosome condensation.
Singh MP, Wijeratne SS, Zempleni J. Singh MP, et al. Arch Biochem Biophys. 2013 Jan 15;529(2):105-11. doi: 10.1016/j.abb.2012.11.005. Epub 2012 Dec 5. Arch Biochem Biophys. 2013. PMID: 23219734 Free PMC article.
Holocarboxylase synthetase (HLCS) is part of a multiprotein gene repression complex and catalyzes the covalent binding of biotin to lysines (K) in histones H3 and H4, thereby creating rare gene repression marks such as K16-biotinylated histone H4 (H4K16bio). …
Holocarboxylase synthetase (HLCS) is part of a multiprotein gene repression complex and catalyzes the covalent binding of biotin to lysines …
ChromID identifies the protein interactome at chromatin marks.
Villaseñor R, Pfaendler R, Ambrosi C, Butz S, Giuliani S, Bryan E, Sheahan TW, Gable AL, Schmolka N, Manzo M, Wirz J, Feller C, von Mering C, Aebersold R, Voigt P, Baubec T. Villaseñor R, et al. Nat Biotechnol. 2020 Jun;38(6):728-736. doi: 10.1038/s41587-020-0434-2. Epub 2020 Mar 2. Nat Biotechnol. 2020. PMID: 32123383 Free PMC article.
In this study, we used natural protein domains as modular building blocks to develop engineered chromatin readers (eCRs) selective for DNA methylation and histone tri-methylation at H3K4, H3K9 and H3K27 residues. We first demonstrated their utility as selective chromatin b …
In this study, we used natural protein domains as modular building blocks to develop engineered chromatin readers (eCRs) selective for DNA m …
Biotinylation of K12 in histone H4 decreases in response to DNA double-strand breaks in human JAr choriocarcinoma cells.
Kothapalli N, Sarath G, Zempleni J. Kothapalli N, et al. J Nutr. 2005 Oct;135(10):2337-42. doi: 10.1093/jn/135.10.2337. J Nutr. 2005. PMID: 16177192 Free PMC article.
Temporal patterns of K12-biotinylation were similar for human lymphoma cells. Phosphorylation of S14 of histone H2B and poly(ADP-ribosylation) of glutamate residues on histone H2A are known markers of DSB in DNA; these modifications increased 10-40 min after …
Temporal patterns of K12-biotinylation were similar for human lymphoma cells. Phosphorylation of S14 of histone H2B and poly(A …
The role of histone H4 biotinylation in the structure of nucleosomes.
Filenko NA, Kolar C, West JT, Smith SA, Hassan YI, Borgstahl GE, Zempleni J, Lyubchenko YL. Filenko NA, et al. PLoS One. 2011 Jan 27;6(1):e16299. doi: 10.1371/journal.pone.0016299. PLoS One. 2011. PMID: 21298003 Free PMC article.
It has been shown that biotinylation of histone H4 at lysine-12 in histone H4 (K12Bio-H4) is associated with repression of a number of genes. We hypothesized that biotinylation modifies the physical structure of nucleosomes, and that biotin-induced con …
It has been shown that biotinylation of histone H4 at lysine-12 in histone H4 (K12Bio-H4) is associated with repression …
Posttranslational modifications of human histone H3: an update.
Xu YM, Du JY, Lau AT. Xu YM, et al. Proteomics. 2014 Sep;14(17-18):2047-60. doi: 10.1002/pmic.201300435. Epub 2014 Aug 8. Proteomics. 2014. PMID: 25044606 Review.
With the advancement of proteomic technology, a growing number of histone PTMs have been identified, including ADP-ribosylation, biotinylation, citrullination, crotonylation, O-GlcNAcylation, glutathionylation, succinylation, and so on. Because of the fast growing l …
With the advancement of proteomic technology, a growing number of histone PTMs have been identified, including ADP-ribosylation, b …
Off-the-shelf proximity biotinylation for interaction proteomics.
Santos-Barriopedro I, van Mierlo G, Vermeulen M. Santos-Barriopedro I, et al. Nat Commun. 2021 Aug 18;12(1):5015. doi: 10.1038/s41467-021-25338-4. Nat Commun. 2021. PMID: 34408139 Free PMC article.
Proximity biotinylation workflows typically require CRISPR-based genetic manipulation of target cells. ...Addition of biotin then triggers bait-proximal protein biotinylation. Biotinylated proteins can subsequently be enriched from crude lysates and identifie …
Proximity biotinylation workflows typically require CRISPR-based genetic manipulation of target cells. ...Addition of biotin then tri …
306 results