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Connecting homocysteine and obesity through pyroptosis, gut microbiome, epigenetics, peroxisome proliferator-activated receptor γ, and zinc finger protein 407.
Laha A, Majumder A, Singh M, Tyagi SC. Laha A, et al. Can J Physiol Pharmacol. 2018 Oct;96(10):971-976. doi: 10.1139/cjpp-2018-0037. Epub 2018 Jun 11. Can J Physiol Pharmacol. 2018. PMID: 29890083 Review.
Although homocysteine (Hcy), a part of the epigenome, contributes to cell death by pyroptosis and decreases peroxisome proliferator-activated receptor γ (PPARγ) levels, the mechanisms are unclear. ...This review suggests that Hcy contributes to pyroptosis, changes gut m
Although homocysteine (Hcy), a part of the epigenome, contributes to cell death by pyroptosis and decreases peroxisome proliferator-a …
Nutrition and Risk of Stroke.
Spence JD. Spence JD. Nutrients. 2019 Mar 17;11(3):647. doi: 10.3390/nu11030647. Nutrients. 2019. PMID: 30884883 Free PMC article. Review.
The role of the intestinal microbiome in cardiovascular risk is emerging; high levels of toxic metabolites produced by intestinal bacteria from meat (particularly red meat) and egg yolk are renally excreted. ...It now clear that B vitamins to lower homocysteine redu …
The role of the intestinal microbiome in cardiovascular risk is emerging; high levels of toxic metabolites produced by intestinal bac …
Nutritional Risk Factors, Microbiota and Parkinson's Disease: What Is the Current Evidence?
Boulos C, Yaghi N, El Hayeck R, Heraoui GN, Fakhoury-Sayegh N. Boulos C, et al. Nutrients. 2019 Aug 14;11(8):1896. doi: 10.3390/nu11081896. Nutrients. 2019. PMID: 31416163 Free PMC article. Review.
Parkinson's disease (PD) is a frequent neurodegenerative disease among elderly people. Genetic and underlying environmental factors seem to be involved in the pathogenesis of PD related to degeneration of dopaminergic neurons in the striatum. In previous experimental resea …
Parkinson's disease (PD) is a frequent neurodegenerative disease among elderly people. Genetic and underlying environmental factors s …
Homocysteine and hydrogen sulfide in epigenetic, metabolic and microbiota related renovascular hypertension.
Weber GJ, Pushpakumar S, Tyagi SC, Sen U. Weber GJ, et al. Pharmacol Res. 2016 Nov;113(Pt A):300-312. doi: 10.1016/j.phrs.2016.09.002. Epub 2016 Sep 4. Pharmacol Res. 2016. PMID: 27602985 Free PMC article. Review.
H(2)S is synthesized primarily through metabolic processes from the amino acid cysteine and homocysteine in various organ systems including neuronal, cardiovascular, gastrointestinal, and kidney. ...In addition, new research into the role of gut microbiota in …
H(2)S is synthesized primarily through metabolic processes from the amino acid cysteine and homocysteine in various organ syst …
Gut microbiota: an overlooked factor that plays a significant role in osteoporosis.
Hao ML, Wang GY, Zuo XQ, Qu CJ, Yao BC, Wang DL. Hao ML, et al. J Int Med Res. 2019 Sep;47(9):4095-4103. doi: 10.1177/0300060519860027. Epub 2019 Aug 22. J Int Med Res. 2019. PMID: 31436117 Free PMC article. Review.
Study of the relationship between intestinal microbiota and osteoporosis is important for maintaining bone health and minimizing osteoporosis....
Study of the relationship between intestinal microbiota and osteoporosis is important for maintaining bone health and minimizing oste …
Nutrition in Stroke Prevention.
Spence JD. Spence JD. Semin Neurol. 2017 Jun;37(3):259-266. doi: 10.1055/s-0037-1603470. Epub 2017 Jul 31. Semin Neurol. 2017. PMID: 28759907 Review. No abstract available.
Advances in Stroke Prevention.
David Spence J. David Spence J. J Transl Int Med. 2018 Oct 9;6(3):105-114. doi: 10.2478/jtim-2018-0024. eCollection 2018 Sep. J Transl Int Med. 2018. PMID: 30425946 Free PMC article.
There is evidence that the Mediterranean diet significantly reduces the risk of stroke and that B vitamins lower homocysteine, thus preventing stroke. ..."Treating arteries instead of treating risk factors," and recent findings related to the intestinal microbiome a …
There is evidence that the Mediterranean diet significantly reduces the risk of stroke and that B vitamins lower homocysteine, thus p …
Gut microbiota in obstructive sleep apnea-hypopnea syndrome: disease-related dysbiosis and metabolic comorbidities.
Ko CY, Liu QQ, Su HZ, Zhang HP, Fan JM, Yang JH, Hu AK, Liu YQ, Chou D, Zeng YM. Ko CY, et al. Clin Sci (Lond). 2019 Apr 12;133(7):905-917. doi: 10.1042/CS20180891. Print 2019 Apr 15. Clin Sci (Lond). 2019. PMID: 30957778 Free PMC article.
Gut microbiota alterations manifest as intermittent hypoxia and fragmented sleep, thereby mimicking obstructive sleep apnea-hypopnea syndrome (OSAHS). ...Functional analysis in the microbiomes of patients revealed alterations; additionally, decreased in short-chain …
Gut microbiota alterations manifest as intermittent hypoxia and fragmented sleep, thereby mimicking obstructive sleep apnea-hypopnea …
A Review of Plant-based Diets to Prevent and Treat Heart Failure.
Kerley CP. Kerley CP. Card Fail Rev. 2018 May;4(1):54-61. doi: 10.15420/cfr.2018:1:1. Card Fail Rev. 2018. PMID: 29892479 Free PMC article. Review.
Potential mechanisms for this include decreased oxidative stress, homocysteine and inflammation levels, as well as higher antioxidant defence and nitric oxide bioavailability with gut microbiome modulation. ...
Potential mechanisms for this include decreased oxidative stress, homocysteine and inflammation levels, as well as higher antioxidant …
Analysis of oral microbiota in patients with obstructive sleep apnea-associated hypertension.
Ko CY, Hu AK, Chou D, Huang LM, Su HZ, Yan FR, Zhang XB, Zhang HP, Zeng YM. Ko CY, et al. Hypertens Res. 2019 Nov;42(11):1692-1700. doi: 10.1038/s41440-019-0260-4. Epub 2019 Apr 11. Hypertens Res. 2019. PMID: 30976074
We examined the fasting levels of cytokines and homocysteine in all participants and analyzed the correlations between the oral microbiota and homocysteine levels. ...Elucidating the differences in the oral microbiome will help us understand the pathog …
We examined the fasting levels of cytokines and homocysteine in all participants and analyzed the correlations between the oral mi
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