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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1975 1
1981 1
1982 1
1983 2
1984 1
1985 1
1986 1
1988 1
1989 4
1990 2
1991 2
1992 2
1993 3
1994 9
1995 4
1996 3
1997 4
1998 6
1999 5
2000 10
2001 7
2002 5
2003 9
2004 9
2005 17
2006 20
2007 24
2008 36
2009 41
2010 44
2011 46
2012 56
2013 56
2014 60
2015 76
2016 67
2017 84
2018 99
2019 78
2020 104
2021 92
2022 107
2023 124
2024 16

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1,200 results

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Page 1
Safety and Toxicology of Magnolol and Honokiol.
Sarrica A, Kirika N, Romeo M, Salmona M, Diomede L. Sarrica A, et al. Planta Med. 2018 Nov;84(16):1151-1164. doi: 10.1055/a-0642-1966. Epub 2018 Jun 20. Planta Med. 2018. PMID: 29925102 Free article. Review.
The biological and pharmacological activities of magnolol and honokiol have been extensively investigated. Here we review the safety and toxicological properties of magnolol and honokiol as pure substances or as components of concentrated MBE, including the potentia …
The biological and pharmacological activities of magnolol and honokiol have been extensively investigated. Here we review the safety …
Mitigation of honokiol on fluoride-induced mitochondrial oxidative stress, mitochondrial dysfunction, and cognitive deficits through activating AMPK/PGC-1alpha/Sirt3.
Wang D, Cao L, Zhou X, Wang G, Ma Y, Hao X, Fan H. Wang D, et al. J Hazard Mater. 2022 Sep 5;437:129381. doi: 10.1016/j.jhazmat.2022.129381. Epub 2022 Jun 16. J Hazard Mater. 2022. PMID: 35752048
The present study investigated the protective actions of honokiol on NaF-elicited cognitive deficits and elucidated the possible mechanism of honokiol-mediated protection. ...Further studies revealed that honokiol activated AMPK and upregulated the PGC-1alpha …
The present study investigated the protective actions of honokiol on NaF-elicited cognitive deficits and elucidated the possible mech …
Honokiol: An anticancer lignan.
Rauf A, Patel S, Imran M, Maalik A, Arshad MU, Saeed F, Mabkhot YN, Al-Showiman SS, Ahmad N, Elsharkawy E. Rauf A, et al. Biomed Pharmacother. 2018 Nov;107:555-562. doi: 10.1016/j.biopha.2018.08.054. Epub 2018 Aug 13. Biomed Pharmacother. 2018. PMID: 30114639 Review.
Honokiol has inhibitory role on the proliferation, invasion and survival of cancer cells in in vitro as well as in vivo studies. ...This review will shed light on the scopes and hurdles in the relevance of the bioactive lignan honokiol in cancer management....
Honokiol has inhibitory role on the proliferation, invasion and survival of cancer cells in in vitro as well as in vivo studies. ...T
Honokiol: A review of its pharmacological potential and therapeutic insights.
Rauf A, Olatunde A, Imran M, Alhumaydhi FA, Aljohani ASM, Khan SA, Uddin MS, Mitra S, Emran TB, Khayrullin M, Rebezov M, Kamal MA, Shariati MA. Rauf A, et al. Phytomedicine. 2021 Sep;90:153647. doi: 10.1016/j.phymed.2021.153647. Epub 2021 Jul 16. Phytomedicine. 2021. PMID: 34362632 Review.
BACKGROUND: Honokiol is a pleiotropic compound which been isolated from Magnolia species such as Magnolia grandiflora and Magnolia dealbata. ...PURPOSE: The objective of this review is to summarize the pharmacological potential and therapeutic insights of honokiol. …
BACKGROUND: Honokiol is a pleiotropic compound which been isolated from Magnolia species such as Magnolia grandiflora and Magnolia de …
The application prospects of honokiol in dermatology.
Li Y, Liang C, Zhou X. Li Y, et al. Dermatol Ther. 2022 Aug;35(8):e15658. doi: 10.1111/dth.15658. Epub 2022 Jun 28. Dermatol Ther. 2022. PMID: 35726011 Free PMC article. Review.
Honokiol is one of the natural extracts of Magnolia officinalis. It is a small molecule, lipophilic compound with extensive biological effects. ...These improvements include physical and chemical penetration enhancers, drug carriers, and chemical derivatives. In conclusion
Honokiol is one of the natural extracts of Magnolia officinalis. It is a small molecule, lipophilic compound with extensive biologica
Honokiol and its analogues as anticancer compounds: Current mechanistic insights and structure-activity relationship.
Prasher P, Fatima R, Sharma M, Tynybekov B, Alshahrani AM, Ateşşahin DA, Sharifi-Rad J, Calina D. Prasher P, et al. Chem Biol Interact. 2023 Dec 1;386:110747. doi: 10.1016/j.cbi.2023.110747. Epub 2023 Oct 8. Chem Biol Interact. 2023. PMID: 37816447 Review.
These factors contribute towards the high bioavailability of honokiol which further support its candidature in medicinal research. ...In this review, we discuss the anticancer properties of honokiol....
These factors contribute towards the high bioavailability of honokiol which further support its candidature in medicinal research. .. …
Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model.
Zhang B, Wang PP, Hu KL, Li LN, Yu X, Lu Y, Chang HS. Zhang B, et al. Molecules. 2019 May 28;24(11):2035. doi: 10.3390/molecules24112035. Molecules. 2019. PMID: 31141940 Free PMC article.
In this study, the lipopolysaccharide (LPS) mouse model was used to study the effect of honokiol on depression-like behavior induced by LPS in mice and its potential mechanism. ...In summary, our results indicate that the anti-depressant-like effects of honokiol are …
In this study, the lipopolysaccharide (LPS) mouse model was used to study the effect of honokiol on depression-like behavior induced …
Honokiol suppresses 2,6-dinitrochlorobenzene-induced atopic dermatitis in mice.
Lee JH, Im DS. Lee JH, et al. J Ethnopharmacol. 2022 May 10;289:115023. doi: 10.1016/j.jep.2022.115023. Epub 2022 Jan 21. J Ethnopharmacol. 2022. PMID: 35074454
Furthermore, the increase in lymph nodes sizes induced by DNCB treatment was reduced by honokiol administration. CONCLUSION: DNCB-induced atopic responses in the ears and lymph nodes were significantly suppressed by honokiol treatment. These results suggested that …
Furthermore, the increase in lymph nodes sizes induced by DNCB treatment was reduced by honokiol administration. CONCLUSION: DNCB-ind …
Honokiol: a novel natural agent for cancer prevention and therapy.
Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP. Arora S, et al. Curr Mol Med. 2012 Dec;12(10):1244-52. doi: 10.2174/156652412803833508. Curr Mol Med. 2012. PMID: 22834827 Free PMC article. Review.
Honokiol (3',5-di-(2-propenyl)-1,1'-biphenyl-2,4'-diol) is a bioactive natural product derived from Magnolia spp. ...Evaluation of honokiol in clinical trials will be the next step towards its possible human applications....
Honokiol (3',5-di-(2-propenyl)-1,1'-biphenyl-2,4'-diol) is a bioactive natural product derived from Magnolia spp. ...Evaluation of
Honokiol attenuates high glucose-induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC-1alpha pathway in Schwann cells.
Hu M, Jiang W, Ye C, Hu T, Yu Q, Meng M, Sun L, Liang J, Chen Y. Hu M, et al. Phytother Res. 2023 Dec;37(12):5787-5802. doi: 10.1002/ptr.7984. Epub 2023 Aug 14. Phytother Res. 2023. PMID: 37580045
This study aimed to investigate the role of AMPK/SIRT1/PGC-1alpha axis in the protective effects of honokiol on DPN. The biochemical assay and JC-1 staining results demonstrated that honokiol reduced HG-induced oxidative stress and ferroptosis as well as mitochondri …
This study aimed to investigate the role of AMPK/SIRT1/PGC-1alpha axis in the protective effects of honokiol on DPN. The biochemical …
1,200 results